MGE detailed information
MGE type: Conjugative plasmid MGE length: 142200 bp
Accession: NZ_CP072323 Location: 1..142200 Organism: Escherichia coli strain EC-JS426 Replicon: plasmid unnamed1
Accession: NZ_CP072323 Location: 1..142200 Organism: Escherichia coli strain EC-JS426 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J6247_RS23030 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| J6247_RS23035 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| J6247_RS23040 (2124) | 2124..2312 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| J6247_RS23045 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| J6247_RS23050 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| J6247_RS23055 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| J6247_RS23060 (7449) | 7449..7628 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| J6247_RS23065 (7767) | 7767..8980 | + | 1214 | WP_172600320.1 | IS3 family transposase IS629 | Transposase |
| J6247_RS23070 (9128) | 9128..9396 | - | 269 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| J6247_RS23075 (9453) | 9453..10150 | + | 698 | WP_224158172.1 | IS1 family transposase IS1S | Transposase |
| J6247_RS23080 (10228) | 10228..11617 | - | 1390 | Protein_10 | ISNCY family transposase ISKpn21 | Transposase |
| J6247_RS23085 (11927) | 11927..12076 | - | 150 | Protein_11 | IS3 family transposase IS2 | Transposase |
| J6247_RS23090 (12254) | 12254..13448 | - | 1195 | Protein_12 | GTP-binding protein | - |
| J6247_RS23095 (14671) | 14671..15907 | - | 1237 | Protein_13 | IS3 family transposase IS2 | Transposase |
| J6247_RS23100 (16534) | 16534..16827 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| J6247_RS23105 (16885) | 16885..17084 | - | 200 | Protein_15 | lysis protein | - |
| J6247_RS23110 (17638) | 17638..18665 | + | 1028 | Protein_16 | integrase core domain-containing protein | - |
| J6247_RS23115 (19976) | 19976..21091 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| J6247_RS23120 (21231) | 21231..24890 | + | 3660 | WP_042047930.1 | Multidrug efflux ATP-binding/permease protein | VF |
| J6247_RS23125 (24994) | 24994..26223 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| J6247_RS23130 (26308) | 26308..27264 | + | 957 | WP_000271276.1 | Ferri-bacillibactin esterase BesA | VF |
| J6247_RS23135 (27309) | 27309..29486 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| J6247_RS24525 (30782) | 30782..31082 | + | 301 | Protein_23 | hypothetical protein | - |
| J6247_RS23145 (31160) | 31160..31507 | - | 348 | WP_000142437.1 | DUF6404 family protein | - |
| J6247_RS23150 (31809) | 31809..32290 | - | 482 | Protein_25 | hypothetical protein | - |
| J6247_RS23155 (32407) | 32407..33255 | - | 849 | WP_054444119.1 | 3'-5' exonuclease | - |
| J6247_RS23160 (33301) | 33301..33579 | - | 279 | WP_244449879.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| J6247_RS23165 (33579) | 33579..33848 | - | 270 | WP_032072813.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| J6247_RS23170 (34763) | 34763..35620 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| J6247_RS24530 (35613) | 35613..35660 | - | 48 | WP_077822033.1 | hypothetical protein | - |
| J6247_RS24535 (35651) | 35651..35887 | + | 237 | WP_223368648.1 | replication protein RepA | - |
| J6247_RS23180 (35913) | 35913..36173 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| J6247_RS23185 (36412) | 36412..36726 | - | 315 | Protein_33 | DUF2726 domain-containing protein | - |
| J6247_RS23190 (36759) | 36759..38510 | - | 1752 | Protein_34 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| J6247_RS23195 (38514) | 38514..38906 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| J6247_RS23200 (39044) | 39044..39928 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| J6247_RS23205 (39960) | 39960..41159 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| J6247_RS23210 (41265) | 41265..41915 | + | 651 | WP_062896472.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| J6247_RS23215 (41947) | 41947..42204 | - | 258 | WP_062896471.1 | hypothetical protein | - |
| J6247_RS23220 (42409) | 42409..43113 | - | 705 | WP_001067856.1 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| J6247_RS23225 (43174) | 43174..45012 | + | 1839 | Protein_41 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| J6247_RS23230 (45046) | 45046..45603 | - | 558 | Protein_42 | IS91 family transposase ISPps1 | Transposase |
| J6247_RS23235 (45715) | 45715..46020 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| J6247_RS23240 (46048) | 46048..47262 | - | 1215 | WP_062896568.1 | Bicyclomycin resistance protein | ARG |
| J6247_RS24540 (47479) | 47479..48363 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| J6247_RS23250 (48394) | 48394..49335 | - | 942 | Protein_46 | IS91 family transposase ISVsa3 | Transposase |
| J6247_RS23255 (49441) | 49441..50277 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| J6247_RS23260 (50277) | 50277..51080 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| J6247_RS23265 (51212) | 51212..52143 | - | 932 | Protein_49 | IS3 family transposase IS1133 | Transposase |
| J6247_RS23270 (52176) | 52176..53144 | + | 969 | WP_000654804.1 | IS5 family transposase IS903B | Transposase |
| J6247_RS23275 (53306) | 53306..54121 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| J6247_RS23280 (54272) | 54272..54976 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| J6247_RS23285 (55031) | 55031..56032 | + | 1002 | Protein_53 | Bcr/CflA family efflux MFS transporter | - |
| J6247_RS23290 (56125) | 56125..56963 | + | 839 | Protein_54 | Streptomycin 3''-adenylyltransferase | ARG |
| J6247_RS23295 (57086) | 57086..57418 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| J6247_RS23300 (57665) | 57665..58297 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| J6247_RS23305 (58320) | 58320..58595 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| J6247_RS23310 (58598) | 58598..59389 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| J6247_RS23315 (59858) | 59858..60103 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| J6247_RS23320 (60141) | 60141..61004 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| J6247_RS23325 (61150) | 61150..61407 | - | 258 | Protein_61 | hypothetical protein | - |
| J6247_RS23330 (61462) | 61462..62166 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| J6247_RS23335 (62230) | 62230..62493 | - | 264 | Protein_63 | MFS transporter | - |
| J6247_RS23340 (62708) | 62708..63546 | - | 839 | Protein_64 | Streptomycin 3''-adenylyltransferase | ARG |
| J6247_RS23345 (63604) | 63604..64212 | - | 609 | WP_000050382.1 | HAD family hydrolase | - |
| J6247_RS23350 (64308) | 64308..65360 | - | 1053 | WP_223714319.1 | alpha/beta fold putative hydrolase EstX | - |
| J6247_RS23355 (65437) | 65437..65619 | - | 183 | Protein_67 | IS6 family transposase IS15DI | Transposase |
| J6247_RS23360 (65767) | 65767..66627 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| J6247_RS23365 (66810) | 66810..67148 | - | 339 | Protein_69 | Tn3 family transposase TnpR_Tn3 | Transposase |
| J6247_RS23370 (67212) | 67212..67916 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| J6247_RS23375 (68038) | 68038..68943 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| J6247_RS23380 (68940) | 68940..70178 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| J6247_RS23385 (70178) | 70178..70762 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| J6247_RS23390 (71255) | 71255..72019 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| J6247_RS24545 (72137) | 72137..72202 | - | 66 | Protein_75 | EAL domain-containing protein | - |
| J6247_RS24550 (72312) | 72312..72428 | - | 117 | Protein_76 | plasmid mobilization relaxosome protein MobC | - |
| J6247_RS23400 (72649) | 72649..73122 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| J6247_RS23405 (73278) | 73278..74291 | + | 1014 | WP_095866698.1 | IS91 family transposase ISAzo26 | Transposase |
| J6247_RS23410 (74494) | 74494..74844 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| J6247_RS23415 (74987) | 74987..76564 | + | 1578 | WP_001323889.1 | Aerotaxis receptor | VF |
| J6247_RS23420 (76754) | 76754..77018 | - | 265 | Protein_81 | hypothetical protein | - |
| J6247_RS23425 (77056) | 77056..77265 | - | 210 | WP_054444114.1 | hemolysin expression modulator Hha | - |
| J6247_RS23430 (77311) | 77311..77772 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| J6247_RS23435 (78015) | 78015..78227 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| J6247_RS23440 (78365) | 78365..78925 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| J6247_RS23445 (78980) | 78980..79726 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| J6247_RS23450 (79746) | 79746..85016 | - | 5271 | WP_011117356.1 | Multifunctional conjugation protein TraI | Relaxase |
| J6247_RS23455 (85098) | 85098..85325 | + | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| J6247_RS23460 (85325) | 85325..85723 | + | 399 | WP_000911324.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| J6247_RS23465 (85732) | 85732..87885 | - | 2154 | WP_000009350.1 | type IV conjugative transfer system coupling protein TraD | - |
| J6247_RS23470 (88138) | 88138..88869 | - | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| J6247_RS23475 (88894) | 88894..89415 | - | 522 | WP_000632670.1 | conjugal transfer entry exclusion protein TraS | - |
| J6247_RS23480 (89448) | 89448..92264 | - | 2817 | WP_001007054.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| J6247_RS23485 (92261) | 92261..93634 | - | 1374 | WP_021553026.1 | conjugal transfer pilus assembly protein TraH | - |
| J6247_RS23490 (93634) | 93634..94014 | - | 381 | WP_042047871.1 | F-type conjugal transfer protein TrbF | - |
| J6247_RS23495 (94001) | 94001..94342 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| J6247_RS23500 (94272) | 94272..94817 | - | 546 | WP_000059850.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| J6247_RS23505 (94804) | 94804..95088 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| J6247_RS23510 (95169) | 95169..95483 | + | 315 | WP_000415567.1 | hypothetical protein | - |
| J6247_RS23515 (95485) | 95485..95832 | - | 348 | WP_001287913.1 | conjugal transfer protein TrbA | - |
| J6247_RS23520 (95848) | 95848..96591 | - | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| J6247_RS23525 (96584) | 96584..96841 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| J6247_RS23530 (96868) | 96868..98676 | - | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| J6247_RS23535 (98673) | 98673..99311 | - | 639 | WP_000777688.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| J6247_RS23540 (99320) | 99320..100312 | - | 993 | WP_000830187.1 | conjugal transfer pilus assembly protein TraU | - |
| J6247_RS23545 (100309) | 100309..100941 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| J6247_RS23550 (100938) | 100938..101324 | - | 387 | WP_000097319.1 | type-F conjugative transfer system protein TrbI | - |
| J6247_RS23555 (101321) | 101321..103948 | - | 2628 | WP_134159231.1 | type IV secretion system protein TraC | - |
| J6247_RS23560 (104108) | 104108..104329 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| J6247_RS23565 (104464) | 104464..104979 | - | 516 | WP_000809841.1 | type IV conjugative transfer system lipoprotein TraV | - |
| J6247_RS23570 (104976) | 104976..105227 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| J6247_RS23575 (105239) | 105239..105436 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| J6247_RS23580 (105423) | 105423..106013 | - | 591 | WP_000002792.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| J6247_RS23585 (106003) | 106003..107430 | - | 1428 | WP_000146692.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| J6247_RS23590 (107430) | 107430..108158 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| J6247_RS23595 (108145) | 108145..108711 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| J6247_RS23600 (108733) | 108733..109044 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| J6247_RS23605 (109059) | 109059..109424 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| J6247_RS23610 (109457) | 109457..109858 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| J6247_RS23615 (109951) | 109951..110640 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| J6247_RS23620 (110827) | 110827..111210 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| J6247_RS23625 (111543) | 111543..112133 | + | 591 | WP_000252680.1 | hypothetical protein | VF |
| J6247_RS23630 (112430) | 112430..113251 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| J6247_RS23635 (113372) | 113372..113659 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| J6247_RS23640 (113684) | 113684..113890 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| J6247_RS24555 (113960) | 113960..114133 | + | 174 | Protein_126 | hypothetical protein | - |
| J6247_RS24560 (114131) | 114131..114361 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| J6247_RS23645 (114581) | 114581..114706 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| J6247_RS24565 (114648) | 114648..114797 | - | 150 | Protein_129 | plasmid maintenance protein Mok | - |
| - (114783) | 114783..115007 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (114783) | 114783..115007 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (114783) | 114783..115007 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (114783) | 114783..115007 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| J6247_RS23650 (114819) | 114819..115007 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| J6247_RS23655 (114976) | 114976..115738 | - | 763 | Protein_131 | plasmid SOS inhibition protein A | - |
| J6247_RS23660 (115735) | 115735..116169 | - | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| J6247_RS23665 (116224) | 116224..118182 | - | 1959 | WP_054444128.1 | ParB/RepB/Spo0J family partition protein | - |
| J6247_RS23670 (118241) | 118241..118474 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| J6247_RS23675 (118530) | 118530..119057 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| J6247_RS24680 (119700) | 119700..119831 | - | 132 | WP_283570452.1 | hypothetical protein | - |
| J6247_RS23680 (119996) | 119996..120559 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| J6247_RS23685 (120605) | 120605..121966 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| J6247_RS23690 (122018) | 122018..122248 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| J6247_RS24570 (122765) | 122765..123018 | + | 254 | Protein_140 | hypothetical protein | - |
| J6247_RS23700 (123242) | 123242..123424 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| J6247_RS23705 (123424) | 123424..123885 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| J6247_RS23710 (123885) | 123885..124310 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| J6247_RS23715 (124712) | 124712..125683 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| J6247_RS23725 (126484) | 126484..126819 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| J6247_RS23730 (126888) | 126888..127235 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| J6247_RS24575 (127232) | 127232..127401 | - | 170 | Protein_148 | hypothetical protein | - |
| J6247_RS23735 (128038) | 128038..129009 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| J6247_RS23740 (129009) | 129009..130175 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| J6247_RS23750 (131328) | 131328..132830 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| J6247_RS23755 (133439) | 133439..133864 | - | 426 | WP_012300440.1 | hypothetical protein | - |
| J6247_RS23760 (134006) | 134006..134485 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| J6247_RS23765 (134925) | 134925..135176 | + | 252 | WP_000163248.1 | hypothetical protein | - |
| J6247_RS23770 (135149) | 135149..135280 | - | 132 | Protein_156 | phosphopyruvate hydratase | - |
| J6247_RS23775 (135278) | 135278..135535 | + | 258 | Protein_157 | Tn3 family transposase | - |
| J6247_RS23780 (135770) | 135770..136627 | - | 858 | WP_000968140.1 | Manganese transport system membrane protein MntB | ARG |
| J6247_RS23785 (136624) | 136624..137481 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| J6247_RS23790 (137478) | 137478..138305 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| J6247_RS23795 (138305) | 138305..139219 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| J6247_RS23800 (139575) | 139575..140272 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| J6247_RS23805 (140452) | 140452..140965 | - | 514 | Protein_163 | DUF4113 domain-containing protein | - |
| J6247_RS23810 (141026) | 141026..141130 | - | 105 | Protein_164 | AAA family ATPase | - |
| J6247_RS23815 (141132) | 141132..141455 | - | 324 | Protein_165 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|