MGE detailed information
MGE type: Conjugative plasmid MGE length: 144098 bp
Accession: NZ_CP069561 Location: 1..144098 Organism: Escherichia coli strain FDAARGOS_1259 Replicon: plasmid unnamed2
Accession: NZ_CP069561 Location: 1..144098 Organism: Escherichia coli strain FDAARGOS_1259 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6J89_RS24585 () | 160..381 | - | 222 | WP_001104892.1 | hypothetical protein | - |
| I6J89_RS24590 () | 382..1065 | - | 684 | WP_000086171.1 | DNA methylase | - |
| I6J89_RS24595 () | 1141..1452 | - | 312 | WP_001309256.1 | hypothetical protein | - |
| I6J89_RS24600 () | 1516..1875 | - | 360 | WP_001336695.1 | DUF1281 domain-containing protein | - |
| I6J89_RS24605 () | 1882..2025 | - | 144 | WP_000270807.1 | DUF1281 domain-containing protein | - |
| I6J89_RS24610 () | 2192..2968 | - | 777 | Protein_6 | hypothetical protein | - |
| I6J89_RS24615 () | 3202..4164 | - | 963 | WP_000756328.1 | ParB/RepB/Spo0J family partition protein | - |
| I6J89_RS24620 () | 4161..5366 | - | 1206 | WP_000817635.1 | Plasmid partition protein A | VF |
| I6J89_RS24625 () | 6124..6375 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| I6J89_RS24630 () | 6372..6659 | + | 288 | WP_001270422.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| I6J89_RS24635 () | 6661..7072 | + | 412 | Protein_11 | DDE-type integrase/transposase/recombinase | - |
| I6J89_RS24640 () | 7716..8693 | + | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| I6J89_RS24645 () | 8936..9676 | - | 741 | WP_001066947.1 | IS91 family transposase ISMno23 | Transposase |
| I6J89_RS24650 () | 9797..9985 | - | 189 | WP_001332784.1 | hypothetical protein | - |
| I6J89_RS24655 () | 10352..11521 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| I6J89_RS24660 () | 11747..11922 | - | 176 | Protein_16 | IS3 family transposase | - |
| I6J89_RS24665 () | 12368..12640 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| I6J89_RS24670 () | 13165..13601 | - | 437 | Protein_18 | IS3 family transposase IS2 | Transposase |
| I6J89_RS24675 () | 13691..14170 | - | 480 | Protein_19 | IS3 family transposase IS629 | Transposase |
| I6J89_RS24680 () | 14254..15762 | - | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| I6J89_RS24685 () | 16435..17174 | - | 740 | Protein_21 | IS3 family transposase IS629 | Transposase |
| I6J89_RS24690 () | 17229..17477 | - | 249 | Protein_22 | IS21 family transposase IS21 | Transposase |
| I6J89_RS24695 () | 17960..18712 | + | 753 | WP_000471454.1 | Chaperone protein caf1M | VF |
| I6J89_RS24700 () | 18775..21291 | + | 2517 | WP_162929852.1 | F1 capsule-anchoring protein | VF |
| I6J89_RS24705 () | 21307..21729 | + | 423 | WP_000243157.1 | Protein AfaD | VF |
| I6J89_RS24710 () | 21837..22322 | + | 486 | WP_204156800.1 | hypothetical protein | - |
| I6J89_RS24715 () | 22726..23142 | + | 417 | WP_000466682.1 | SdiA-regulated domain-containing protein | - |
| I6J89_RS24720 () | 23347..24138 | - | 792 | WP_000456855.1 | Virulence regulon transcriptional activator VirF | VF |
| I6J89_RS24725 () | 24463..24968 | + | 506 | Protein_29 | IS3 family transposase IS3H | Transposase |
| I6J89_RS24730 () | 24961..25074 | + | 114 | Protein_30 | transposase | - |
| I6J89_RS24735 () | 25224..26222 | + | 999 | WP_000756334.1 | ABC transporter substrate-binding protein | - |
| I6J89_RS24740 () | 26222..27259 | + | 1038 | WP_001545318.1 | Hemin transport system permease protein HmuU | VF |
| I6J89_RS24745 () | 27259..28020 | + | 762 | WP_000020504.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| I6J89_RS24750 () | 28077..29264 | + | 1188 | WP_025999368.1 | MFS transporter | - |
| I6J89_RS24755 () | 29342..29617 | - | 276 | WP_000877662.1 | bacteriocin immunity protein | - |
| I6J89_RS24760 () | 29975..30274 | - | 300 | WP_000119542.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| I6J89_RS24765 () | 30264..30527 | - | 264 | WP_001089474.1 | hypothetical protein | - |
| I6J89_RS24770 () | 30634..30894 | - | 261 | WP_001545316.1 | hypothetical protein | - |
| I6J89_RS24775 () | 31104..31586 | - | 483 | WP_001337004.1 | hypothetical protein | - |
| I6J89_RS24780 () | 31703..32551 | - | 849 | WP_001057995.1 | 3'-5' exonuclease | - |
| I6J89_RS24785 () | 32667..32816 | - | 150 | Protein_41 | IS3 family transposase | - |
| I6J89_RS24790 () | 32855..34393 | - | 1539 | WP_000099150.1 | IS66 family transposase ISEc22 | Transposase |
| I6J89_RS24795 () | 34442..34789 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| I6J89_RS24800 () | 34786..35190 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| I6J89_RS24805 () | 35306..36340 | + | 1035 | Protein_45 | IS3 family transposase IS3 | Transposase |
| I6J89_RS24810 () | 36569..38077 | - | 1509 | WP_204147730.1 | group II intron reverse transcriptase/maturase | - |
| I6J89_RS24815 () | 38750..39100 | - | 351 | Protein_47 | IS3 family transposase IS629 | Transposase |
| I6J89_RS24820 () | 39186..40685 | + | 1500 | WP_000143800.1 | IS21 family transposase ISEc10 | Transposase |
| I6J89_RS24825 () | 40682..41437 | + | 756 | WP_000065240.1 | IS21 family transposase ISEc10 | Transposase |
| I6J89_RS24830 () | 41328..41905 | - | 578 | Protein_50 | IS3 family transposase IS629 | Transposase |
| I6J89_RS24835 () | 41931..42236 | + | 306 | Protein_51 | IS91 family transposase ISSbo1 | Transposase |
| I6J89_RS24840 () | 42759..43934 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| I6J89_RS24845 () | 44003..46264 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| I6J89_RS24850 () | 46433..47209 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| I6J89_RS24855 () | 47217..48092 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| I6J89_RS24860 () | 48424..49110 | - | 687 | Protein_56 | replication initiation protein | - |
| I6J89_RS24865 () | 50680..50898 | - | 219 | WP_001336934.1 | hypothetical protein | - |
| I6J89_RS24870 () | 51027..51374 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| I6J89_RS24875 () | 51394..51903 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| I6J89_RS24880 () | 51900..52160 | - | 261 | WP_000371883.1 | hypothetical protein | - |
| I6J89_RS24885 () | 52262..53001 | + | 740 | Protein_61 | IS3 family transposase IS629 | Transposase |
| I6J89_RS24890 () | 53674..55182 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| I6J89_RS24895 () | 55272..55745 | + | 474 | Protein_63 | IS3 family transposase IS629 | Transposase |
| I6J89_RS24900 () | 55748..56317 | - | 570 | WP_001336919.1 | Serine protease EspC | VF |
| I6J89_RS24905 () | 56419..57398 | + | 980 | Protein_65 | IS5 family transposase ISKpn26 | Transposase |
| I6J89_RS24910 () | 57548..58180 | - | 633 | Protein_66 | histidine-type phosphatase | - |
| I6J89_RS24915 () | 58302..58787 | - | 486 | WP_023910483.1 | hypothetical protein | - |
| I6J89_RS24920 () | 58812..59297 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| I6J89_RS24925 () | 59284..59979 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| I6J89_RS24930 () | 59984..61114 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| I6J89_RS24935 () | 61104..62387 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| I6J89_RS24940 () | 62390..63769 | - | 1380 | WP_059342161.1 | DUF2318 domain-containing protein | - |
| I6J89_RS24945 () | 63873..64400 | - | 528 | WP_000178050.1 | iron transporter | - |
| I6J89_RS24950 () | 64441..66327 | - | 1887 | WP_122998458.1 | FTR1 family iron permease | - |
| I6J89_RS24955 () | 66674..67489 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| I6J89_RS24960 () | 67589..68293 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6J89_RS24965 () | 68345..68437 | - | 93 | Protein_77 | EAL domain-containing protein | - |
| I6J89_RS24970 () | 68640..69653 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| I6J89_RS24975 () | 69811..70284 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| I6J89_RS24980 () | 70415..71203 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| I6J89_RS24985 () | 71409..71756 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| I6J89_RS24990 () | 71750..72589 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| I6J89_RS24995 () | 72717..72920 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| I6J89_RS25000 () | 73076..74281 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| I6J89_RS25005 () | 74292..74597 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| I6J89_RS25010 () | 74641..74706 | + | 66 | Protein_86 | EAL domain-containing protein | - |
| I6J89_RS25015 () | 74824..75588 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| I6J89_RS25020 () | 76081..76665 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| I6J89_RS25025 () | 76665..77903 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| I6J89_RS25030 () | 77900..78805 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| I6J89_RS25035 () | 78927..79631 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6J89_RS25040 () | 79696..80781 | - | 1086 | Protein_92 | transposase | - |
| I6J89_RS25045 () | 80856..81524 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| I6J89_RS25050 () | 81560..81796 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| I6J89_RS25055 () | 81793..82155 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| I6J89_RS25060 () | 82173..83867 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| I6J89_RS25065 () | 83919..84341 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| I6J89_RS25070 () | 84377..84652 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| I6J89_RS25075 () | 84666..85016 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| I6J89_RS25080 () | 85088..85522 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| I6J89_RS25085 () | 85629..86326 | - | 698 | Protein_101 | IS1 family transposase IS1R | Transposase |
| I6J89_RS25090 () | 86575..86976 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| I6J89_RS25095 () | 86909..87166 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| I6J89_RS25100 () | 87259..87912 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| I6J89_RS25105 () | 88010..88150 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| I6J89_RS25110 () | 88851..89708 | - | 858 | WP_001537577.1 | incFII family plasmid replication initiator RepA | - |
| I6J89_RS25115 () | 89701..89775 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| I6J89_RS25120 () | 90009..90266 | - | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| I6J89_RS25125 () | 90551..90700 | - | 150 | WP_001336447.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 90748..90804 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 90748..90804 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 90748..90804 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 90748..90804 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| I6J89_RS25130 () | 90899..91336 | - | 438 | WP_000872609.1 | hypothetical protein | - |
| I6J89_RS25135 () | 91489..91872 | - | 384 | WP_001109264.1 | hypothetical protein | - |
| I6J89_RS25140 () | 91975..92436 | - | 462 | WP_000760080.1 | thermonuclease family protein | - |
| I6J89_RS25145 () | 93189..93392 | - | 204 | WP_001336517.1 | hypothetical protein | - |
| I6J89_RS25150 () | 93544..94101 | - | 558 | WP_000139329.1 | fertility inhibition protein FinO | - |
| I6J89_RS25155 () | 94156..94902 | - | 747 | WP_000205709.1 | conjugal transfer pilus acetylase TraX | - |
| I6J89_RS25160 () | 94922..100192 | - | 5271 | WP_001545323.1 | Multifunctional conjugation protein TraI | Relaxase |
| I6J89_RS25165 () | 100192..102534 | - | 2343 | WP_125133978.1 | Coupling protein TraD | VF |
| I6J89_RS25170 () | 102585..103322 | - | 738 | WP_000199901.1 | hypothetical protein | - |
| I6J89_RS25175 () | 103525..104256 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| I6J89_RS25180 () | 104288..104785 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| I6J89_RS25185 () | 104804..107623 | - | 2820 | WP_001537571.1 | conjugal transfer mating pair stabilization protein TraG | - |
| I6J89_RS25190 () | 107620..108993 | - | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| I6J89_RS25195 () | 108980..109405 | - | 426 | WP_001336804.1 | F-type conjugal transfer protein TrbF | - |
| I6J89_RS25200 () | 109326..109700 | - | 375 | WP_071586940.1 | P-type conjugative transfer protein TrbJ | - |
| I6J89_RS25205 () | 109630..110175 | - | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| I6J89_RS25210 () | 110162..110446 | - | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| I6J89_RS25215 () | 110527..110787 | + | 261 | WP_000736412.1 | hypothetical protein | - |
| I6J89_RS25220 () | 110843..111184 | - | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| I6J89_RS25225 () | 111198..111941 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| I6J89_RS25230 () | 111934..112191 | - | 258 | WP_000864310.1 | conjugal transfer protein TrbE | - |
| I6J89_RS25235 () | 112218..114068 | - | 1851 | WP_125118040.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| I6J89_RS25240 () | 114065..114487 | - | 423 | WP_001229309.1 | HNH endonuclease | - |
| I6J89_RS25245 () | 114512..114883 | - | 372 | WP_000174465.1 | hypothetical protein | - |
| I6J89_RS25250 () | 114880..115518 | - | 639 | WP_000087539.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| I6J89_RS25255 () | 115545..116063 | - | 519 | WP_000009088.1 | hypothetical protein | - |
| I6J89_RS25260 () | 116126..116434 | - | 309 | WP_000412445.1 | hypothetical protein | - |
| I6J89_RS25265 () | 116461..117453 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| I6J89_RS25270 () | 117450..118082 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| I6J89_RS25275 () | 118079..118465 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| I6J89_RS25280 () | 118462..121092 | - | 2631 | WP_000069771.1 | type IV secretion system protein TraC | - |
| I6J89_RS25285 () | 121757..122230 | - | 474 | WP_000549566.1 | hypothetical protein | - |
| I6J89_RS25290 () | 122223..122636 | - | 414 | WP_000549574.1 | hypothetical protein | - |
| I6J89_RS25295 () | 122629..122850 | - | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| I6J89_RS25300 () | 122985..123500 | - | 516 | WP_000809872.1 | type IV conjugative transfer system lipoprotein TraV | - |
| I6J89_RS25305 () | 123500..123850 | - | 351 | WP_071586941.1 | conjugal transfer protein TrbD | - |
| I6J89_RS25310 () | 123804..124391 | - | 588 | WP_001309238.1 | conjugal transfer protein TraP | - |
| I6J89_RS25315 () | 124360..125811 | - | 1452 | WP_000146663.1 | conjugal transfer protein TraB | - |
| I6J89_RS25320 () | 125811..126515 | - | 705 | WP_149013885.1 | type-F conjugative transfer system secretin TraK | - |
| I6J89_RS25325 () | 126526..127092 | - | 567 | Protein_149 | type IV conjugative transfer system protein TraE | - |
| I6J89_RS25330 () | 127114..127425 | - | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| I6J89_RS25335 () | 127440..127799 | - | 360 | WP_001099001.1 | type IV conjugative transfer system pilin TraA | - |
| I6J89_RS25340 () | 127832..128227 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| I6J89_RS25345 () | 128326..129015 | - | 690 | WP_000283387.1 | conjugal transfer transcriptional regulator TraJ | - |
| I6J89_RS25350 () | 129202..129585 | - | 384 | WP_001151538.1 | relaxosome protein TraM | - |
| I6J89_RS25355 () | 129906..130508 | + | 603 | Protein_155 | hypothetical protein | VF |
| I6J89_RS25360 () | 130805..131626 | - | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| I6J89_RS25365 () | 131736..132032 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| I6J89_RS25370 () | 132424..132628 | + | 205 | Protein_158 | pilus protein | - |
| I6J89_RS25375 () | 132929..133087 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 133131..133355 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 133131..133355 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 133131..133355 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 133131..133355 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| I6J89_RS25380 () | 133167..133346 | + | 180 | WP_001309233.1 | hypothetical protein | - |
| I6J89_RS25385 () | 133367..134086 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| I6J89_RS25390 () | 134083..134517 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| I6J89_RS25395 () | 134586..136550 | - | 1965 | WP_059342185.1 | ParB/RepB/Spo0J family partition protein | - |
| I6J89_RS25400 () | 136611..136844 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| I6J89_RS25405 () | 136902..137429 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| I6J89_RS25410 () | 137731..138192 | + | 462 | WP_106426744.1 | hypothetical protein | - |
| I6J89_RS25415 () | 138278..138841 | - | 564 | WP_001309257.1 | class I SAM-dependent methyltransferase | - |
| I6J89_RS25420 () | 138888..140249 | - | 1362 | WP_000170705.1 | DUF3560 domain-containing protein | - |
| I6J89_RS25425 () | 140301..140531 | - | 231 | WP_001537563.1 | hypothetical protein | - |
| I6J89_RS25430 () | 141212..141520 | + | 309 | WP_050576143.1 | hypothetical protein | - |
| I6J89_RS25435 () | 141499..141690 | - | 192 | WP_001027049.1 | hypothetical protein | - |
| I6J89_RS25440 () | 141690..142109 | - | 420 | WP_000271761.1 | DUF1380 family protein | - |
| I6J89_RS25445 () | 142156..142458 | - | 303 | WP_001364029.1 | antirestriction protein | - |
| I6J89_RS25450 () | 142995..143765 | - | 771 | WP_001044390.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|