MGE detailed information
MGE type: Mobilizable plasmid MGE length: 134972 bp
Accession: NZ_CP069172 Location: 1..134972 Organism: Klebsiella pneumoniae strain KPWX136 Replicon: plasmid pB
Accession: NZ_CP069172 Location: 1..134972 Organism: Klebsiella pneumoniae strain KPWX136 Replicon: plasmid pB
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JLH18_RS28065 () | 472..702 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| JLH18_RS28070 () | 2102..3769 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| JLH18_RS28075 () | 4083..4274 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| JLH18_RS28080 () | 4271..4693 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| JLH18_RS28085 () | 4740..5165 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| JLH18_RS28090 () | 5583..6359 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| JLH18_RS28095 () | 6410..6844 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| JLH18_RS28100 () | 6858..7079 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| JLH18_RS28105 () | 7080..7763 | - | 684 | WP_000085883.1 | DNA methylase | - |
| JLH18_RS28110 () | 7840..8133 | - | 294 | WP_032146011.1 | hypothetical protein | - |
| JLH18_RS28115 () | 8280..9242 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| JLH18_RS28120 () | 9245..9595 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| JLH18_RS28125 () | 9718..9999 | - | 282 | WP_001333089.1 | hypothetical protein | - |
| JLH18_RS28130 () | 10127..10361 | - | 235 | Protein_14 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JLH18_RS28135 () | 11810..11875 | - | 66 | Protein_15 | IS1 family transposase | - |
| JLH18_RS28140 () | 11941..12645 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| JLH18_RS28145 () | 12733..13014 | + | 282 | WP_015059004.1 | sodium/hydrogen exchanger | - |
| JLH18_RS28150 () | 13095..13850 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| JLH18_RS28155 () | 14020..14880 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| JLH18_RS28160 () | 15063..15599 | - | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| JLH18_RS28165 () | 15691..15879 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| JLH18_RS28170 () | 15889..16506 | + | 618 | Protein_22 | IS91 family transposase ISSbo1 | Transposase |
| JLH18_RS28175 () | 16557..17261 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLH18_RS28180 () | 17717..18307 | - | 591 | Protein_24 | IS91 family transposase ISSbo1 | Transposase |
| JLH18_RS28185 () | 18372..19076 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLH18_RS28190 () | 19156..19605 | + | 450 | Protein_26 | PAS domain-containing protein | - |
| JLH18_RS28195 () | 19673..20770 | - | 1098 | Protein_27 | TonB-dependent receptor | - |
| JLH18_RS28200 () | 20827..21795 | - | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| JLH18_RS28205 () | 21830..22705 | - | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| JLH18_RS28210 () | 22955..23146 | - | 192 | Protein_30 | transposase | - |
| JLH18_RS28215 () | 23216..23920 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLH18_RS28220 () | 23986..24531 | + | 546 | Protein_32 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JLH18_RS28225 () | 24567..24982 | - | 416 | Protein_33 | IS1 family transposase | - |
| JLH18_RS28230 () | 25231..25632 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JLH18_RS28235 () | 25565..25822 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JLH18_RS28240 () | 25915..26568 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JLH18_RS28245 () | 27507..28364 | - | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| JLH18_RS28250 () | 28357..28431 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| JLH18_RS28255 () | 28676..28924 | - | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| JLH18_RS28260 () | 29208..29357 | - | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 29402..29461 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 29402..29461 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 29402..29461 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 29402..29461 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| JLH18_RS28265 () | 29662..29892 | - | 231 | WP_001736714.1 | hypothetical protein | - |
| JLH18_RS28270 () | 30056..30655 | - | 600 | WP_032083981.1 | hypothetical protein | - |
| JLH18_RS28275 () | 31041..31241 | - | 201 | WP_015059022.1 | hypothetical protein | - |
| JLH18_RS28280 () | 31373..31933 | - | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| JLH18_RS28285 () | 31988..32734 | - | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| JLH18_RS28290 () | 32754..32915 | - | 162 | Protein_46 | DNA helicase | - |
| JLH18_RS28295 () | 32979..33683 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLH18_RS28300 () | 33735..34079 | + | 345 | Protein_48 | IS6 family transposase IS26 | Transposase |
| JLH18_RS28305 () | 34134..34499 | - | 366 | Protein_49 | type IV conjugative transfer system protein TraE | - |
| JLH18_RS28310 () | 34519..34824 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| JLH18_RS28315 () | 34838..35206 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| JLH18_RS28320 () | 35268..35474 | - | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| JLH18_RS28325 () | 35589..36326 | - | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| JLH18_RS28330 () | 36526..36942 | - | 417 | WP_014343494.1 | relaxosome protein TraM | - |
| JLH18_RS28335 () | 37333..37818 | + | 486 | WP_014343495.1 | hypothetical protein | VF |
| JLH18_RS28340 () | 37851..38180 | - | 330 | WP_013214015.1 | hypothetical protein | - |
| JLH18_RS28345 () | 38213..39034 | - | 822 | WP_004152492.1 | DUF945 domain-containing protein | - |
| JLH18_RS28350 () | 39971..40249 | - | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| JLH18_RS28355 () | 40239..40559 | - | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JLH18_RS28360 () | 40640..40864 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| JLH18_RS28365 () | 40875..41087 | - | 213 | WP_014343500.1 | hypothetical protein | - |
| JLH18_RS28370 () | 41148..41504 | - | 357 | WP_014343501.1 | hypothetical protein | - |
| JLH18_RS28375 () | 42345..42662 | - | 318 | WP_014343505.1 | hypothetical protein | - |
| JLH18_RS28380 () | 42677..43027 | - | 351 | WP_040245917.1 | hypothetical protein | - |
| JLH18_RS28385 () | 43024..43296 | - | 273 | WP_040245921.1 | hypothetical protein | - |
| JLH18_RS28390 () | 43989..44147 | - | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| JLH18_RS28395 () | 44375..44749 | - | 375 | WP_014343510.1 | hypothetical protein | - |
| JLH18_RS28400 () | 44805..45131 | - | 327 | WP_013023807.1 | hypothetical protein | - |
| JLH18_RS28405 () | 45128..45856 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| JLH18_RS28410 () | 45853..46284 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| JLH18_RS28415 () | 46329..48386 | - | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| JLH18_RS28420 () | 48456..48704 | - | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| JLH18_RS28425 () | 48753..49295 | - | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| JLH18_RS28430 () | 50128..50691 | - | 564 | WP_014343514.1 | methyltransferase | - |
| JLH18_RS28435 () | 50739..52094 | - | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| JLH18_RS28440 () | 52146..52376 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| JLH18_RS28445 () | 52468..52695 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| JLH18_RS28450 () | 53375..53695 | - | 321 | WP_001568049.1 | hypothetical protein | - |
| JLH18_RS28455 () | 53730..53984 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| JLH18_RS28460 () | 54172..54363 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| JLH18_RS28465 () | 54406..54912 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| JLH18_RS28470 () | 54955..55383 | - | 429 | WP_001568045.1 | antirestriction protein | - |
| JLH18_RS28475 () | 56064..56831 | - | 768 | WP_013214013.1 | hypothetical protein | - |
| JLH18_RS28480 () | 56885..57304 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| JLH18_RS28485 () | 57314..57535 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| JLH18_RS28490 () | 57535..58236 | - | 702 | WP_001568041.1 | DNA methylase | - |
| JLH18_RS28495 () | 58673..58903 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| JLH18_RS28500 () | 58966..59637 | - | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| JLH18_RS28505 () | 59640..60611 | - | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| JLH18_RS28510 () | 60860..62347 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| JLH18_RS28515 () | 62754..63185 | + | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| JLH18_RS28520 () | 63185..64456 | + | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| JLH18_RS28525 () | 64538..65512 | - | 975 | WP_011977819.1 | ParB/RepB/Spo0J family partition protein | - |
| JLH18_RS28530 () | 65512..66717 | - | 1206 | WP_011977818.1 | AAA family ATPase | - |
| JLH18_RS28535 () | 67827..68693 | - | 867 | WP_004118283.1 | replication initiation protein | - |
| JLH18_RS28540 () | 69229..69342 | + | 114 | WP_014343462.1 | hypothetical protein | - |
| JLH18_RS28545 () | 69471..69728 | + | 258 | WP_013214010.1 | hypothetical protein | - |
| JLH18_RS28550 () | 69774..70553 | - | 780 | WP_013214009.1 | site-specific integrase | - |
| JLH18_RS28555 () | 70737..71741 | - | 1005 | WP_011977814.1 | hypothetical protein | - |
| JLH18_RS28560 () | 71771..71974 | - | 204 | WP_011977813.1 | hypothetical protein | - |
| JLH18_RS28565 () | 72020..72541 | - | 522 | WP_013214008.1 | hypothetical protein | - |
| JLH18_RS28570 () | 72599..72991 | - | 393 | WP_011977811.1 | hypothetical protein | - |
| JLH18_RS28575 () | 73028..73972 | - | 945 | WP_011977810.1 | hypothetical protein | - |
| JLH18_RS28580 () | 74133..74378 | - | 246 | Protein_104 | hypothetical protein | - |
| JLH18_RS28585 () | 74557..75531 | - | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| JLH18_RS28590 () | 76168..77076 | + | 909 | WP_023302803.1 | HNH endonuclease | - |
| JLH18_RS28595 () | 77463..77813 | - | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| JLH18_RS28600 () | 77957..78388 | - | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| JLH18_RS28605 () | 78639..80114 | - | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| JLH18_RS28610 () | 80107..80787 | - | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| JLH18_RS28615 () | 80977..82362 | + | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| JLH18_RS28620 () | 82391..82753 | + | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| JLH18_RS28625 () | 82867..84159 | + | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| JLH18_RS28630 () | 84170..87316 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| JLH18_RS28635 () | 87403..87843 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| JLH18_RS28640 () | 87970..90417 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| JLH18_RS28645 () | 90458..90655 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| JLH18_RS28650 () | 90689..91426 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| JLH18_RS28655 () | 91693..92160 | - | 468 | WP_048336866.1 | hypothetical protein | - |
| JLH18_RS28660 () | 92449..93429 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| JLH18_RS28665 () | 93594..95411 | + | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| JLH18_RS28670 () | 95417..96307 | + | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| JLH18_RS28675 () | 96347..96727 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| JLH18_RS28680 () | 96732..97661 | + | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| JLH18_RS28685 () | 97716..98396 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| JLH18_RS28690 () | 98393..99793 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| JLH18_RS28695 () | 100321..101325 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| JLH18_RS28700 () | 101404..101838 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| JLH18_RS28705 () | 101910..102260 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| JLH18_RS28710 () | 102274..102549 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| JLH18_RS28715 () | 102585..103007 | + | 423 | WP_001447540.1 | organomercurial transporter MerC | - |
| JLH18_RS28720 () | 103059..104753 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| JLH18_RS28725 () | 104771..105133 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| JLH18_RS28730 () | 105130..105366 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| JLH18_RS28735 () | 105402..106070 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| JLH18_RS28740 () | 106145..107317 | + | 1173 | Protein_136 | transposase | - |
| JLH18_RS28745 () | 107382..108086 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLH18_RS28750 () | 108138..108599 | + | 462 | Protein_138 | Tn3 family transposase TnpR_Tn3 | Transposase |
| JLH18_RS28755 () | 108722..109702 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| JLH18_RS28760 () | 109978..110859 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| JLH18_RS28765 () | 111109..111990 | - | 882 | Protein_141 | IS1182 family transposase ISKpn6 | Transposase |
| JLH18_RS28770 () | 112094..112390 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
| JLH18_RS28775 () | 112436..112591 | - | 156 | WP_013213988.1 | hypothetical protein | - |
| JLH18_RS28780 () | 112719..113144 | - | 426 | WP_013213989.1 | antirestriction protein | - |
| JLH18_RS28785 () | 113255..113533 | - | 279 | WP_013213990.1 | hypothetical protein | - |
| JLH18_RS28790 () | 114067..114684 | - | 618 | Protein_146 | replication protein | - |
| JLH18_RS28795 () | 115076..115636 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| JLH18_RS28800 () | 115640..118606 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| JLH18_RS28805 () | 118642..118710 | - | 69 | Protein_149 | IS6 family transposase | - |
| JLH18_RS28810 () | 118847..119707 | + | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| JLH18_RS28815 () | 119728..120489 | - | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| JLH18_RS28820 () | 120751..121653 | + | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| JLH18_RS28825 () | 121665..122917 | + | 1253 | Protein_153 | four-carbon acid sugar kinase family protein | - |
| JLH18_RS28830 () | 122910..123233 | + | 324 | Protein_154 | class II aldolase/adducin family protein | - |
| JLH18_RS28835 () | 123287..123991 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLH18_RS28840 () | 124272..124655 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| JLH18_RS28845 () | 124932..125579 | + | 648 | WP_015059008.1 | hypothetical protein | VF |
| JLH18_RS28850 () | 125876..126697 | - | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| JLH18_RS28855 () | 126808..127104 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| JLH18_RS28860 () | 127404..127781 | + | 378 | Protein_160 | hypothetical protein | - |
| JLH18_RS28865 () | 128019..128177 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 128221..128445 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 128221..128445 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 128221..128445 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 128221..128445 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| JLH18_RS28870 () | 128457..129176 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| JLH18_RS28875 () | 129173..129607 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| JLH18_RS28880 () | 129676..131699 | - | 2024 | Protein_164 | ParB/RepB/Spo0J family partition protein | - |
| JLH18_RS28885 () | 131760..131993 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| JLH18_RS28890 () | 132051..132578 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| JLH18_RS28895 () | 133421..133984 | - | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|