MGE detailed information
MGE type: Mobilizable plasmid MGE length: 122076 bp
Accession: NZ_CP066251 Location: 1..122076 Organism: Klebsiella pneumoniae strain CRKP52R Replicon: plasmid p3
Accession: NZ_CP066251 Location: 1..122076 Organism: Klebsiella pneumoniae strain CRKP52R Replicon: plasmid p3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JCR34_RS28035 () | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| JCR34_RS28040 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JCR34_RS28045 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JCR34_RS28050 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JCR34_RS28055 () | 3383..3798 | + | 416 | Protein_5 | IS1 family transposase IS1R | Transposase |
| JCR34_RS28060 () | 3834..4379 | - | 546 | Protein_6 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JCR34_RS28065 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JCR34_RS28070 () | 5219..5410 | + | 192 | Protein_8 | transposase | - |
| JCR34_RS28075 () | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| JCR34_RS28080 () | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| JCR34_RS28085 () | 7595..8692 | + | 1098 | Protein_11 | TonB-dependent receptor | - |
| JCR34_RS28090 () | 8760..9209 | - | 450 | Protein_12 | PAS domain-containing protein | - |
| JCR34_RS28095 () | 9289..9993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JCR34_RS28100 () | 10058..10648 | + | 591 | Protein_14 | IS91 family transposase ISSbo1 | Transposase |
| JCR34_RS28105 () | 11104..11808 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JCR34_RS28110 () | 11859..12476 | - | 618 | Protein_16 | IS91 family transposase ISSbo1 | Transposase |
| JCR34_RS28115 () | 12486..12674 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| JCR34_RS28120 () | 12766..13302 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| JCR34_RS28125 () | 13485..14345 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| JCR34_RS28130 () | 14515..15270 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| JCR34_RS28135 () | 15351..15632 | - | 282 | WP_015059004.1 | sodium/hydrogen exchanger | - |
| JCR34_RS28140 () | 15720..16424 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| JCR34_RS28145 () | 16475..17611 | + | 1137 | WP_198809478.1 | DUF3560 domain-containing protein | - |
| JCR34_RS28150 () | 17658..18221 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| JCR34_RS28155 () | 19064..19591 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| JCR34_RS28160 () | 19649..19882 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| JCR34_RS28165 () | 19943..21966 | + | 2024 | Protein_27 | ParB/RepB/Spo0J family partition protein | - |
| JCR34_RS28170 () | 22035..22469 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| JCR34_RS28175 () | 22466..23185 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 23197..23421 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 23197..23421 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 23197..23421 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 23197..23421 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| JCR34_RS28180 () | 23465..23623 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JCR34_RS28185 () | 23861..24238 | - | 378 | Protein_31 | hypothetical protein | - |
| JCR34_RS28190 () | 24538..24834 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| JCR34_RS28195 () | 24945..25766 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| JCR34_RS28200 () | 26063..26710 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| JCR34_RS28205 () | 26987..27370 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| JCR34_RS28210 () | 27651..28355 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JCR34_RS28215 () | 28409..28732 | - | 324 | Protein_37 | class II aldolase/adducin family protein | - |
| JCR34_RS28220 () | 28725..29977 | - | 1253 | Protein_38 | four-carbon acid sugar kinase family protein | - |
| JCR34_RS28225 () | 29989..30891 | - | 903 | WP_004151610.1 | NAD(P)-dependent oxidoreductase | - |
| JCR34_RS28230 () | 31152..31913 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| JCR34_RS28235 () | 31934..32794 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| JCR34_RS28240 () | 32931..32999 | + | 69 | Protein_42 | IS6 family transposase | - |
| JCR34_RS28245 () | 33035..36001 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| JCR34_RS28250 () | 36005..36565 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| JCR34_RS28255 () | 36957..37574 | + | 618 | Protein_45 | replication protein | - |
| JCR34_RS28260 () | 38108..38386 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| JCR34_RS28265 () | 38497..38922 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| JCR34_RS28270 () | 39050..39205 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| JCR34_RS28275 () | 39251..39547 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| JCR34_RS28280 () | 39651..40532 | + | 882 | Protein_50 | IS1182 family transposase ISKpn6 | Transposase |
| JCR34_RS28285 () | 40782..41663 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| JCR34_RS28290 () | 41939..42919 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| JCR34_RS28295 () | 43042..43503 | - | 462 | Protein_53 | Tn3 family transposase TnpR_Tn3 | Transposase |
| JCR34_RS28300 () | 43555..44259 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JCR34_RS28305 () | 44324..45496 | - | 1173 | Protein_55 | transposase | - |
| JCR34_RS28310 () | 45571..46239 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| JCR34_RS28315 () | 46275..46511 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| JCR34_RS28320 () | 46508..46870 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| JCR34_RS28325 () | 46888..48582 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| JCR34_RS28330 () | 48634..49056 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| JCR34_RS28335 () | 49092..49367 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| JCR34_RS28340 () | 49381..49731 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| JCR34_RS28345 () | 49803..50237 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| JCR34_RS28350 () | 50316..51320 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| JCR34_RS28355 () | 51848..53248 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| JCR34_RS28360 () | 53245..53925 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| JCR34_RS28365 () | 53980..54909 | - | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| JCR34_RS28370 () | 54914..55294 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| JCR34_RS28375 () | 55334..56224 | - | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| JCR34_RS28380 () | 56230..58047 | - | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| JCR34_RS28385 () | 58281..58748 | + | 468 | WP_048336866.1 | hypothetical protein | - |
| JCR34_RS28390 () | 59015..59752 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| JCR34_RS28395 () | 59786..59983 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| JCR34_RS28400 () | 60024..62471 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| JCR34_RS28405 () | 62598..63038 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| JCR34_RS28410 () | 63125..66271 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| JCR34_RS28415 () | 66282..67574 | - | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| JCR34_RS28420 () | 67688..68050 | - | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| JCR34_RS28425 () | 68079..69464 | - | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| JCR34_RS28430 () | 69654..70334 | + | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| JCR34_RS28435 () | 70327..71802 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| JCR34_RS28440 () | 72053..72484 | + | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| JCR34_RS28445 () | 72628..72978 | + | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| JCR34_RS28450 () | 73365..74273 | - | 909 | WP_023302803.1 | HNH endonuclease | - |
| JCR34_RS28455 () | 74910..75884 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| JCR34_RS28460 () | 76063..76308 | + | 246 | Protein_86 | hypothetical protein | - |
| JCR34_RS28465 () | 76469..77413 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| JCR34_RS28470 () | 77450..77842 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| JCR34_RS28475 () | 77900..78421 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| JCR34_RS28480 () | 78467..78670 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| JCR34_RS28485 () | 78700..79704 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| JCR34_RS28490 () | 79888..80667 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| JCR34_RS28495 () | 80713..80970 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| JCR34_RS28500 () | 81099..81212 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| JCR34_RS28505 () | 81748..82614 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| JCR34_RS28510 () | 83724..84929 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| JCR34_RS28515 () | 84929..85903 | + | 975 | WP_011977819.1 | ParB/RepB/Spo0J family partition protein | - |
| JCR34_RS28520 () | 85985..87256 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| JCR34_RS28525 () | 87256..87687 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| JCR34_RS28530 () | 88094..89581 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| JCR34_RS28535 () | 89830..90801 | + | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| JCR34_RS28540 () | 90804..91475 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| JCR34_RS28545 () | 91538..91768 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| JCR34_RS28550 () | 92205..92906 | + | 702 | WP_001568041.1 | DNA methylase | - |
| JCR34_RS28555 () | 92906..93127 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| JCR34_RS28560 () | 93137..93556 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| JCR34_RS28565 () | 93610..94377 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| JCR34_RS28570 () | 95058..95486 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| JCR34_RS28575 () | 95529..96035 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| JCR34_RS28580 () | 96078..96269 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| JCR34_RS28585 () | 96457..96711 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| JCR34_RS28590 () | 96746..97066 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| JCR34_RS28595 () | 97746..97973 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| JCR34_RS28600 () | 98065..98295 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| JCR34_RS28605 () | 98347..99702 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| JCR34_RS28610 () | 99750..100313 | + | 564 | WP_014343514.1 | methyltransferase | - |
| JCR34_RS28615 () | 101146..101688 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| JCR34_RS28620 () | 101737..101985 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| JCR34_RS28625 () | 102055..104112 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| JCR34_RS28630 () | 104157..104588 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| JCR34_RS28635 () | 104585..105313 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| JCR34_RS28640 () | 105310..105636 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| JCR34_RS28645 () | 105692..106066 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| JCR34_RS28650 () | 106294..106452 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| JCR34_RS28655 () | 107145..107417 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| JCR34_RS28660 () | 107414..107764 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| JCR34_RS28665 () | 107779..108096 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| JCR34_RS28670 () | 108937..109293 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| JCR34_RS28675 () | 109354..109566 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| JCR34_RS28680 () | 109577..109801 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| JCR34_RS28685 () | 109882..110202 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JCR34_RS28690 () | 110192..110470 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| JCR34_RS28695 () | 111407..112228 | + | 822 | WP_004152492.1 | DUF945 domain-containing protein | - |
| JCR34_RS28700 () | 112261..112590 | + | 330 | WP_013214015.1 | hypothetical protein | - |
| JCR34_RS28705 () | 112623..113108 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| JCR34_RS28710 () | 113499..113915 | + | 417 | WP_014343494.1 | relaxosome protein TraM | - |
| JCR34_RS28715 () | 114115..114852 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| JCR34_RS28720 () | 114967..115173 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| JCR34_RS28725 () | 115235..115603 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| JCR34_RS28730 () | 115617..115922 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| JCR34_RS28735 () | 115942..116307 | + | 366 | Protein_141 | type IV conjugative transfer system protein TraE | - |
| JCR34_RS28740 () | 116362..116706 | - | 345 | Protein_142 | IS6 family transposase IS26 | Transposase |
| JCR34_RS28745 () | 116758..117462 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JCR34_RS28750 () | 117526..117687 | + | 162 | Protein_144 | DNA helicase | - |
| JCR34_RS28755 () | 117707..118453 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| JCR34_RS28760 () | 118508..119068 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| JCR34_RS28765 () | 119200..119400 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| JCR34_RS28770 () | 119786..120385 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| JCR34_RS28775 () | 120549..120779 | + | 231 | WP_001736714.1 | hypothetical protein | - |
| - () | 120980..121039 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 120980..121039 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 120980..121039 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 120980..121039 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| JCR34_RS28780 () | 121084..121233 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JCR34_RS28785 () | 121517..121765 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|