MGE detailed information
MGE type: Conjugative plasmid MGE length: 147528 bp
Accession: NZ_CP065437 Location: 1..147528 Organism: Klebsiella pneumoniae strain Dirty Dan Replicon: plasmid pDirtyDan_01
Accession: NZ_CP065437 Location: 1..147528 Organism: Klebsiella pneumoniae strain Dirty Dan Replicon: plasmid pDirtyDan_01
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6Z21_RS25470 () | 1..103 | + | 103 | WP_194428931.1 | IS3 family transposase | - |
| I6Z21_RS25475 () | 321..671 | + | 351 | WP_012540252.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| I6Z21_RS25480 () | 719..1081 | + | 363 | WP_012540111.1 | arsenite efflux transporter metallochaperone ArsD | - |
| I6Z21_RS25485 () | 1099..2850 | + | 1752 | WP_094716535.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| I6Z21_RS25490 () | 2898..4187 | + | 1290 | WP_012540054.1 | arsenite efflux transporter membrane subunit ArsB | - |
| I6Z21_RS25495 () | 4200..4625 | + | 426 | WP_012540118.1 | glutaredoxin-dependent arsenate reductase | - |
| I6Z21_RS25500 () | 4660..5196 | - | 537 | WP_012540238.1 | hypothetical protein | VF |
| I6Z21_RS25505 () | 5321..7072 | - | 1752 | WP_162866166.1 | Arsenical pump-driving ATPase | VF |
| I6Z21_RS25510 () | 7099..7461 | - | 363 | WP_094716534.1 | arsenic metallochaperone ArsD family protein | - |
| I6Z21_RS25515 () | 7537..8082 | - | 546 | WP_012540227.1 | sigma-70 family RNA polymerase sigma factor | - |
| I6Z21_RS25520 () | 8091..8804 | - | 714 | WP_012540184.1 | arsenical resistance protein ArsH | - |
| I6Z21_RS25525 () | 8806..9129 | - | 324 | WP_012540250.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| I6Z21_RS25530 () | 9428..9694 | + | 267 | WP_012540086.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| I6Z21_RS25535 () | 9682..10167 | + | 486 | WP_013087172.1 | GNAT family N-acetyltransferase | Toxin Detail |
| I6Z21_RS25540 () | 10507..10668 | + | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| I6Z21_RS25545 () | 11363..11635 | + | 273 | WP_004182067.1 | hypothetical protein | - |
| I6Z21_RS25550 () | 11632..11982 | + | 351 | WP_023320095.1 | hypothetical protein | - |
| I6Z21_RS25555 () | 12618..12974 | + | 357 | WP_004152717.1 | hypothetical protein | - |
| I6Z21_RS25560 () | 13035..13247 | + | 213 | WP_004152718.1 | hypothetical protein | - |
| I6Z21_RS25565 () | 13258..13482 | + | 225 | WP_004152719.1 | hypothetical protein | - |
| I6Z21_RS25570 () | 13563..13883 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| I6Z21_RS25575 () | 13873..14151 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| I6Z21_RS25580 () | 14152..14565 | + | 414 | WP_004182074.1 | helix-turn-helix domain-containing protein | - |
| I6Z21_RS25585 () | 15399..16210 | + | 812 | Protein_23 | DUF945 domain-containing protein | - |
| I6Z21_RS25590 () | 16243..16572 | + | 330 | WP_094716524.1 | hypothetical protein | - |
| I6Z21_RS25595 () | 16605..17090 | - | 486 | WP_004178063.1 | hypothetical protein | VF |
| I6Z21_RS25600 () | 17525..17917 | + | 393 | WP_004206766.1 | relaxosome protein TraM | - |
| I6Z21_RS25605 () | 18124..18819 | + | 696 | WP_015065624.1 | transcriptional regulator TraJ family protein | - |
| I6Z21_RS25610 () | 18903..19274 | + | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| I6Z21_RS25615 () | 19328..19696 | + | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| I6Z21_RS25620 () | 19710..20015 | + | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| I6Z21_RS25625 () | 20035..20601 | + | 567 | WP_004152602.1 | type IV conjugative transfer system protein TraE | - |
| I6Z21_RS25630 () | 20588..21328 | + | 741 | WP_004152497.1 | type-F conjugative transfer system secretin TraK | - |
| I6Z21_RS25635 () | 21328..22753 | + | 1426 | Protein_33 | conjugal transfer protein TraB | - |
| I6Z21_RS25640 () | 22746..23171 | + | 426 | WP_094716525.1 | conjugal transfer protein TraP | - |
| I6Z21_RS25645 () | 23371..23940 | + | 570 | WP_015065628.1 | type IV conjugative transfer system lipoprotein TraV | - |
| I6Z21_RS25650 () | 24315..24494 | + | 180 | WP_071609111.1 | hypothetical protein | - |
| I6Z21_RS25655 () | 24523..24813 | + | 291 | WP_032426790.1 | hypothetical protein | - |
| I6Z21_RS25660 () | 24837..25055 | + | 219 | WP_004171484.1 | hypothetical protein | - |
| I6Z21_RS25665 () | 25056..25373 | + | 318 | WP_094716526.1 | hypothetical protein | - |
| I6Z21_RS25670 () | 25440..25844 | + | 405 | WP_023320104.1 | hypothetical protein | - |
| I6Z21_RS25675 () | 25869..26267 | + | 399 | WP_015065631.1 | hypothetical protein | - |
| I6Z21_RS25680 () | 26339..28979 | + | 2641 | Protein_42 | type IV secretion system protein TraC | - |
| I6Z21_RS25685 () | 28979..29368 | + | 390 | WP_004152591.1 | type-F conjugative transfer system protein TrbI | - |
| I6Z21_RS25690 () | 29368..29994 | + | 627 | WP_065810625.1 | type-F conjugative transfer system protein TraW | - |
| I6Z21_RS25695 () | 30005..30997 | + | 993 | WP_094716527.1 | conjugal transfer pilus assembly protein TraU | - |
| I6Z21_RS25700 () | 31010..31648 | + | 639 | WP_015065635.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| I6Z21_RS25705 () | 31707..33662 | + | 1956 | WP_046041928.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| I6Z21_RS25710 () | 33694..33930 | + | 237 | WP_016529263.1 | conjugal transfer protein TrbE | - |
| I6Z21_RS25715 () | 34158..34484 | + | 327 | WP_016529362.1 | hypothetical protein | - |
| I6Z21_RS25720 () | 34505..35257 | + | 753 | WP_015065637.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| I6Z21_RS25725 () | 35268..35507 | + | 240 | WP_094716528.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| I6Z21_RS25730 () | 35479..36036 | + | 558 | WP_194428932.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| I6Z21_RS25735 () | 36081..36524 | + | 444 | WP_015065638.1 | F-type conjugal transfer protein TrbF | - |
| I6Z21_RS25740 () | 36502..37881 | + | 1380 | WP_011977731.1 | conjugal transfer protein TraH | - |
| I6Z21_RS25745 () | 37881..40730 | + | 2850 | WP_129073754.1 | conjugal transfer mating pair stabilization protein TraG | - |
| I6Z21_RS25750 () | 40736..41263 | + | 528 | WP_016528837.1 | conjugal transfer entry exclusion protein TraS | - |
| I6Z21_RS25755 () | 41453..42184 | + | 732 | WP_004152629.1 | complement resistance protein TraT | - |
| I6Z21_RS25760 () | 42543..44854 | + | 2312 | Protein_58 | type IV conjugative transfer system coupling protein TraD | - |
| I6Z21_RS25765 () | 44854..50115 | + | 5262 | WP_194428933.1 | Multifunctional conjugation protein TraI | Relaxase |
| I6Z21_RS25770 () | 50195..50920 | + | 726 | WP_023284651.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| I6Z21_RS25775 () | 51076..51672 | + | 597 | WP_023307531.1 | fertility inhibition protein FinO | - |
| I6Z21_RS25780 () | 51692..52039 | + | 348 | WP_015065646.1 | hypothetical protein | - |
| I6Z21_RS25785 () | 52254..52799 | - | 546 | WP_015065647.1 | hypothetical protein | - |
| I6Z21_RS25790 () | 53155..55476 | + | 2322 | WP_116440810.1 | klebicin B-related nuclease bacteriocin | - |
| I6Z21_RS25795 () | 55478..55757 | + | 280 | Protein_65 | bacteriocin immunity protein | - |
| I6Z21_RS25800 () | 56098..56576 | + | 479 | Protein_66 | phospholipase D family protein | - |
| I6Z21_RS25805 () | 56897..57175 | + | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| I6Z21_RS25810 () | 57392..57469 | + | 78 | WP_004171457.1 | RepA leader peptide Tap | - |
| I6Z21_RS25815 () | 57462..58319 | + | 858 | WP_094716533.1 | incFII family plasmid replication initiator RepA | - |
| I6Z21_RS25820 () | 59505..59570 | + | 66 | Protein_70 | hypothetical protein | - |
| I6Z21_RS25825 () | 59636..60340 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| I6Z21_RS25830 () | 60392..60526 | - | 135 | Protein_72 | dihydropteroate synthase | - |
| I6Z21_RS25835 () | 60520..60855 | - | 336 | WP_052238321.1 | ethidium bromide resistance protein | - |
| I6Z21_RS25840 () | 60748..61113 | + | 366 | WP_025999322.1 | hydrogenase maturation nickel metallochaperone HypA | - |
| I6Z21_RS25845 () | 61117..61992 | - | 876 | WP_004193231.1 | LysR family transcriptional regulator AmpR | - |
| I6Z21_RS25850 () | 61967..62206 | - | 240 | WP_162270619.1 | hypothetical protein | - |
| I6Z21_RS25855 () | 62103..63242 | + | 1140 | WP_004236386.1 | Beta-lactamase | ARG |
| I6Z21_RS25860 () | 63437..64231 | + | 795 | Protein_78 | alpha-2-macroglobulin family protein | - |
| I6Z21_RS25865 () | 64593..64823 | - | 231 | WP_004193241.1 | phage shock protein PspD | - |
| I6Z21_RS25870 () | 64832..65191 | - | 360 | WP_004193243.1 | envelope stress response membrane protein PspC | - |
| I6Z21_RS25875 () | 65191..65415 | - | 225 | WP_004193245.1 | envelope stress response membrane protein PspB | - |
| I6Z21_RS25880 () | 65470..66138 | - | 669 | WP_003020532.1 | phage shock protein PspA | - |
| I6Z21_RS25885 () | 66294..67283 | + | 990 | WP_017900991.1 | Psp operon transcriptional activator | VF |
| I6Z21_RS25890 () | 67366..68010 | + | 645 | WP_017900990.1 | Pentapeptide repeat protein | ARG |
| I6Z21_RS25895 () | 68109..68813 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6Z21_RS25900 () | 68888..69220 | + | 333 | Protein_86 | phosphotransferase | - |
| I6Z21_RS25905 () | 69220..70056 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| I6Z21_RS25910 () | 70159..70356 | - | 198 | Protein_88 | histidinol-phosphate aminotransferase | - |
| I6Z21_RS25915 () | 70504..71364 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| I6Z21_RS25920 () | 71547..72008 | - | 462 | Protein_90 | Tn3 family transposase TnpR_Tn3 | Transposase |
| I6Z21_RS25925 () | 72080..72763 | - | 684 | WP_151292568.1 | IS6 family transposase IS15DI | Transposase |
| I6Z21_RS25930 () | 72824..74518 | + | 1695 | Protein_92 | Tn3 family transposase ISKox2 | Transposase |
| I6Z21_RS25935 () | 74624..75484 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| I6Z21_RS25940 () | 75497..76039 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| I6Z21_RS25945 () | 76828..77274 | + | 447 | Protein_95 | DUF3363 domain-containing protein | - |
| I6Z21_RS25950 () | 77491..78705 | + | 1215 | WP_000214121.1 | Bicyclomycin resistance protein | ARG |
| I6Z21_RS25955 () | 78733..79038 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| I6Z21_RS25960 () | 79150..80643 | + | 1494 | WP_194428934.1 | IS91 family transposase ISVsa3 | Transposase |
| I6Z21_RS25965 () | 80879..81121 | - | 243 | Protein_99 | phosphoglucosamine mutase | - |
| I6Z21_RS25970 () | 81208..82023 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| I6Z21_RS25975 () | 82353..82529 | + | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| I6Z21_RS25980 () | 82711..83538 | - | 828 | Protein_102 | IS110 family transposase IS5075 | Transposase |
| I6Z21_RS25985 () | 83603..84307 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6Z21_RS25990 () | 84497..85312 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| I6Z21_RS25995 () | 85463..86167 | + | 705 | WP_156664158.1 | IS6 family transposase IS26 | Transposase |
| I6Z21_RS26000 () | 86289..87194 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| I6Z21_RS26005 () | 87191..88429 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| I6Z21_RS26010 () | 88429..89013 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| I6Z21_RS26015 () | 89506..90270 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| I6Z21_RS26020 () | 90388..90453 | - | 66 | Protein_110 | EAL domain-containing protein | - |
| I6Z21_RS26025 () | 90497..90801 | - | 305 | Protein_111 | helix-turn-helix transcriptional regulator | - |
| I6Z21_RS26030 () | 90812..92017 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| I6Z21_RS26035 () | 92173..92376 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| I6Z21_RS26040 () | 92504..93343 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| I6Z21_RS26045 () | 93337..93684 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| I6Z21_RS26050 () | 93848..94639 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| I6Z21_RS26055 () | 94645..94935 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| I6Z21_RS26060 () | 95047..95544 | - | 498 | WP_194428935.1 | Dihydrofolate reductase | ARG |
| I6Z21_RS26065 () | 95689..96702 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| I6Z21_RS26070 () | 96905..97255 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| I6Z21_RS26075 () | 97431..97991 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| I6Z21_RS26080 () | 97995..100772 | + | 2778 | WP_194428936.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| I6Z21_RS26085 () | 100830..101072 | + | 243 | WP_000844627.1 | transposase | - |
| I6Z21_RS26090 () | 101104..101754 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| I6Z21_RS26095 () | 101860..103059 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| I6Z21_RS26100 () | 103091..103975 | - | 885 | WP_194428937.1 | EamA family transporter | - |
| I6Z21_RS26105 () | 104113..104520 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| I6Z21_RS26110 () | 104509..106260 | + | 1752 | Protein_128 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| I6Z21_RS26115 () | 106296..106823 | - | 528 | Protein_129 | IS110 family transposase IS1663 | Transposase |
| I6Z21_RS26120 () | 107639..108946 | + | 1308 | WP_124847134.1 | hypothetical protein | - |
| I6Z21_RS26125 () | 110194..110289 | - | 96 | Protein_131 | IS3 family transposase | - |
| I6Z21_RS26130 () | 110379..110645 | - | 267 | Protein_132 | ISNCY family transposase | - |
| I6Z21_RS26135 () | 110935..111801 | + | 867 | WP_052264179.1 | hypothetical protein | - |
| I6Z21_RS26140 () | 111956..112243 | + | 288 | WP_042938777.1 | chorismate mutase | - |
| I6Z21_RS26145 () | 112345..112839 | - | 495 | WP_065808010.1 | DNA-binding protein | - |
| I6Z21_RS26150 () | 112870..113445 | - | 576 | WP_065808008.1 | hypothetical protein | - |
| I6Z21_RS26155 () | 113486..113701 | - | 216 | WP_065808007.1 | hypothetical protein | - |
| I6Z21_RS26160 () | 113940..114266 | - | 327 | WP_124989605.1 | hypothetical protein | - |
| I6Z21_RS26165 () | 114345..114563 | - | 219 | WP_021312527.1 | hypothetical protein | - |
| I6Z21_RS26170 () | 114627..114872 | - | 246 | WP_065905238.1 | hypothetical protein | - |
| I6Z21_RS26175 () | 114907..115323 | - | 417 | WP_021312475.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| I6Z21_RS26180 () | 115320..115550 | - | 231 | WP_021312476.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| I6Z21_RS26185 () | 115870..117435 | + | 1566 | WP_094716520.1 | ATP-binding protein | - |
| I6Z21_RS26190 () | 117492..118361 | - | 870 | WP_094716519.1 | hypothetical protein | - |
| I6Z21_RS26195 () | 118363..119451 | - | 1089 | WP_094716522.1 | transcriptional regulator | - |
| I6Z21_RS26200 () | 120067..122070 | - | 2004 | WP_094716518.1 | AAA-like domain-containing protein | - |
| I6Z21_RS26205 () | 123210..123950 | + | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| I6Z21_RS26210 () | 124655..125665 | - | 1011 | WP_094716517.1 | RepB family plasmid replication initiator protein | - |
| I6Z21_RS26215 () | 126417..127583 | + | 1167 | WP_000523812.1 | Sporulation initiation inhibitor protein Soj | VF |
| I6Z21_RS26220 () | 127583..128554 | + | 972 | WP_094716516.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| I6Z21_RS26225 () | 129923..130228 | - | 306 | WP_094716521.1 | hypothetical protein | - |
| I6Z21_RS26230 () | 130282..130533 | - | 252 | WP_004118488.1 | plasmid stabilization protein | - |
| I6Z21_RS26235 () | 130612..131883 | - | 1272 | WP_004118485.1 | Y-family DNA polymerase | - |
| I6Z21_RS26240 () | 131883..132308 | - | 426 | WP_047062069.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| I6Z21_RS26245 () | 132521..132751 | + | 231 | WP_004118481.1 | hypothetical protein | - |
| I6Z21_RS26250 () | 133274..133699 | + | 426 | WP_004118478.1 | antirestriction protein | - |
| I6Z21_RS26255 () | 133936..134190 | + | 255 | WP_094716515.1 | DNA polymerase III subunit theta | - |
| I6Z21_RS26260 () | 134225..134542 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| I6Z21_RS26265 () | 135326..135553 | + | 228 | WP_004118469.1 | hypothetical protein | - |
| I6Z21_RS26270 () | 135645..135875 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| I6Z21_RS26275 () | 135927..137282 | + | 1356 | WP_094716542.1 | DUF3560 domain-containing protein | - |
| I6Z21_RS26280 () | 137330..137893 | + | 564 | WP_004152756.1 | methyltransferase | - |
| I6Z21_RS26285 () | 138727..139269 | + | 543 | WP_094716539.1 | single-stranded DNA-binding protein | - |
| I6Z21_RS26290 () | 139318..139566 | + | 249 | WP_094716538.1 | DUF905 domain-containing protein | - |
| I6Z21_RS26295 () | 139636..141693 | + | 2058 | WP_094716537.1 | ParB/RepB/Spo0J family partition protein | - |
| I6Z21_RS26300 () | 141738..142169 | + | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| I6Z21_RS26305 () | 142166..142894 | + | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| I6Z21_RS26310 () | 142891..143217 | + | 327 | WP_004152639.1 | hypothetical protein | - |
| I6Z21_RS26315 () | 143273..143647 | + | 375 | WP_023320094.1 | hypothetical protein | - |
| I6Z21_RS26320 () | 143847..144356 | + | 510 | WP_047727560.1 | IS3 family transposase ISKpn8 | Transposase |
| I6Z21_RS26325 () | 144486..145250 | - | 765 | WP_094716536.1 | IS21 family transposase ISEc10 | Transposase |
| I6Z21_RS26330 () | 145247..146745 | - | 1499 | Protein_172 | IS21 family transposase ISEc10 | Transposase |
| I6Z21_RS26335 () | 146840..147528 | + | 689 | Protein_173 | IS3 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|