MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 159421 bp
Accession: NZ_CP065431 Location: 812559..971979 Organism: Streptococcus suis strain YP20190405 Replicon: chromosome
Accession: NZ_CP065431 Location: 812559..971979 Organism: Streptococcus suis strain YP20190405 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I5W22_RS03930 () | 808289..810157 | + | 1869 | WP_012775435.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| I5W22_RS03935 () | 810158..810493 | + | 336 | WP_002934966.1 | hypothetical protein | - |
| I5W22_RS03940 () | 810589..811548 | + | 960 | WP_012775086.1 | ROK family glucokinase | - |
| I5W22_RS03945 () | 811674..811952 | + | 279 | WP_012775087.1 | hypothetical protein | - |
| I5W22_RS03950 () | 811964..812266 | + | 303 | WP_012775088.1 | hypothetical protein | - |
| I5W22_RS03955 () | 812319..813158 | + | 840 | WP_011922359.1 | thymidylate synthase | - |
| I5W22_RS03960 () | 813444..813956 | + | 513 | WP_011922360.1 | dihydrofolate reductase | - |
| I5W22_RS03965 () | 813959..814132 | + | 174 | WP_002934972.1 | hypothetical protein | - |
| I5W22_RS03970 () | 814154..815380 | + | 1227 | WP_002934974.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | - |
| I5W22_RS03975 () | 815436..816023 | + | 588 | WP_012775089.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| I5W22_RS03980 () | 816046..816459 | + | 414 | WP_012028095.1 | nucleoside-diphosphate kinase | - |
| I5W22_RS03985 () | 816563..817234 | + | 672 | WP_011922364.1 | HIRAN domain-containing protein | - |
| I5W22_RS03990 () | 817516..819348 | + | 1833 | WP_002943192.1 | translation elongation factor 4 | - |
| I5W22_RS03995 () | 819398..819580 | - | 183 | WP_002934978.1 | 4-oxalocrotonate tautomerase | - |
| I5W22_RS04000 () | 819715..821022 | + | 1308 | WP_012028097.1 | excalibur calcium-binding domain-containing protein | - |
| I5W22_RS04005 () | 821407..821988 | + | 582 | WP_012028098.1 | thymidine kinase | - |
| I5W22_RS04010 () | 822439..823518 | + | 1080 | WP_012775090.1 | peptide chain release factor 1 | - |
| I5W22_RS04015 () | 823518..824351 | + | 834 | WP_011922371.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| I5W22_RS04020 () | 824338..824946 | + | 609 | WP_011922372.1 | threonylcarbamoyl-AMP synthase | - |
| I5W22_RS04025 () | 824943..825374 | + | 432 | WP_011922373.1 | GNAT family N-acetyltransferase | - |
| I5W22_RS04030 () | 825398..826657 | + | 1260 | WP_011922374.1 | serine hydroxymethyltransferase | - |
| I5W22_RS04035 () | 826657..827631 | + | 975 | WP_002943200.1 | nucleoid-associated protein | - |
| I5W22_RS04040 () | 827632..828231 | + | 600 | WP_011922375.1 | lysozyme family protein | - |
| I5W22_RS04045 () | 828332..829090 | + | 759 | WP_002943202.1 | 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase | VF |
| I5W22_RS04050 () | 829107..829856 | + | 750 | WP_011922377.1 | translation initiation factor 1 | - |
| I5W22_RS04055 () | 829878..830231 | + | 354 | WP_002943204.1 | HIRAN domain-containing protein | - |
| I5W22_RS04060 () | 830252..831199 | - | 948 | WP_011922378.1 | hypothetical protein | - |
| I5W22_RS04065 () | 831227..832015 | - | 789 | WP_012775093.1 | hypothetical protein | - |
| I5W22_RS04070 () | 832211..833908 | + | 1698 | WP_012775094.1 | AAA family ATPase | - |
| I5W22_RS04075 () | 833905..834954 | + | 1050 | WP_011922381.1 | 5-methylcytosine-specific restriction endonuclease system specificity protein McrC | - |
| I5W22_RS04080 () | 835160..836470 | - | 1311 | WP_011922382.1 | Tyrosine recombinase XerC ; Integrase | Integrase |
| I5W22_RS04085 () | 836442..836675 | - | 234 | WP_011922383.1 | DUF3173 domain-containing protein | - |
| I5W22_RS04090 () | 836653..837891 | - | 1239 | WP_014636592.1 | replication initiation protein | - |
| I5W22_RS04095 () | 838401..838925 | - | 525 | WP_011922385.1 | hypothetical protein | - |
| I5W22_RS04100 () | 838953..839258 | - | 306 | WP_012775097.1 | hypothetical protein | - |
| I5W22_RS04105 () | 839511..840812 | + | 1302 | WP_012775098.1 | hypothetical protein | - |
| I5W22_RS04110 () | 840837..841043 | - | 207 | WP_012775099.1 | helix-turn-helix domain-containing protein | - |
| I5W22_RS04115 () | 841160..842137 | + | 978 | WP_011922387.1 | membrane protein | - |
| I5W22_RS04120 () | 842153..842992 | + | 840 | WP_011922388.1 | hypothetical protein | - |
| I5W22_RS04125 () | 843009..843413 | + | 405 | WP_012028114.1 | hypothetical protein | - |
| I5W22_RS04130 () | 843568..844590 | + | 1023 | WP_012775100.1 | hypothetical protein | - |
| I5W22_RS04135 () | 844580..846196 | + | 1617 | WP_011922392.1 | hypothetical protein | - |
| I5W22_RS04140 () | 846408..847958 | - | 1551 | WP_002934999.1 | glutamine-hydrolyzing GMP synthase | - |
| I5W22_RS04145 () | 848234..848932 | + | 699 | WP_002943214.1 | GntR family transcriptional regulator | - |
| I5W22_RS04150 () | 849035..849367 | + | 333 | WP_002935001.1 | putative DNA-binding protein | - |
| I5W22_RS04155 () | 849380..850918 | + | 1539 | WP_011922394.1 | signal recognition particle protein | - |
| I5W22_RS04160 () | 851112..851780 | + | 669 | WP_011922395.1 | SatD family protein | - |
| I5W22_RS04165 () | 851784..852524 | + | 741 | WP_011922396.1 | DUF3307 domain-containing protein | - |
| I5W22_RS04170 () | 852589..853026 | + | 438 | WP_011922397.1 | AAA family ATPase | - |
| I5W22_RS04175 () | 853677..853982 | + | 306 | WP_015445217.1 | Abi family protein | - |
| I5W22_RS04180 () | 854030..854638 | + | 609 | Protein_775 | Abi family protein | - |
| I5W22_RS04185 () | 854997..856067 | + | 1071 | WP_012775436.1 | Tyrosine recombinase XerS ; Integrase | Integrase |
| I5W22_RS04190 () | 856137..857645 | - | 1509 | WP_011922400.1 | hypothetical protein | VF |
| I5W22_RS04195 () | 857721..858662 | - | 942 | WP_012775102.1 | sensor histidine kinase | - |
| I5W22_RS04200 () | 858659..859324 | - | 666 | WP_012775103.1 | Chemotaxis response regulator protein-glutamate methylesterase | VF |
| I5W22_RS04205 () | 859363..859620 | - | 258 | WP_011922404.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| I5W22_RS04210 () | 859604..859855 | - | 252 | WP_012775104.1 | hypothetical protein | Antitoxin Detail |
| I5W22_RS04215 () | 859947..861917 | - | 1971 | WP_012775105.1 | FtsX-like permease family protein | - |
| I5W22_RS04220 () | 861918..862670 | - | 753 | WP_011922409.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| I5W22_RS04225 () | 862806..863540 | - | 735 | WP_011922410.1 | ABC transporter permease | - |
| I5W22_RS04230 () | 863542..864288 | - | 747 | WP_011922411.1 | ABC transporter permease | - |
| I5W22_RS04235 () | 864290..865192 | - | 903 | WP_011922412.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| I5W22_RS04240 () | 865213..865590 | - | 378 | WP_011922413.1 | NisI/SpaI family lantibiotic immunity lipoprotein | - |
| I5W22_RS04245 () | 865603..865743 | - | 141 | WP_012775106.1 | hypothetical protein | - |
| I5W22_RS04250 () | 865883..867049 | - | 1167 | WP_011922414.1 | carbamoyl phosphate synthase large subunit | - |
| I5W22_RS04255 () | 867067..867813 | - | 747 | WP_011922415.1 | esterase family protein | - |
| I5W22_RS04260 () | 867844..868671 | - | 828 | WP_011922416.1 | alpha/beta hydrolase | - |
| I5W22_RS04265 () | 868785..869789 | - | 1005 | WP_012775107.1 | winged helix DNA-binding domain-containing protein | - |
| I5W22_RS04270 () | 869854..870690 | - | 837 | WP_014636394.1 | AraC family transcriptional regulator | - |
| I5W22_RS04275 () | 870767..872101 | - | 1335 | WP_011922419.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| I5W22_RS04280 () | 872297..873046 | - | 750 | WP_011922420.1 | HAD family hydrolase | - |
| I5W22_RS04285 () | 873171..873536 | - | 366 | WP_002936483.1 | 50S ribosomal protein L7/L12 | - |
| I5W22_RS04290 () | 873602..874096 | - | 495 | WP_002936486.1 | 50S ribosomal protein L10 | - |
| I5W22_RS04295 () | 874673..876766 | - | 2094 | WP_012775128.1 | type I DNA topoisomerase | - |
| I5W22_RS04300 () | 876859..877701 | - | 843 | WP_012775129.1 | DNA-processing protein DprA | - |
| I5W22_RS04305 () | 877760..878317 | - | 558 | WP_011922479.1 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase | VF |
| I5W22_RS04310 () | 878328..878588 | - | 261 | WP_009909865.1 | metal-sensitive transcriptional regulator | - |
| I5W22_RS04315 () | 878695..879018 | + | 324 | WP_012775130.1 | rhodanese-like domain-containing protein | - |
| I5W22_RS04320 () | 879015..880673 | + | 1659 | WP_011922481.1 | FAD-dependent oxidoreductase | - |
| I5W22_RS04325 () | 880781..881332 | + | 552 | WP_011922482.1 | DUF1836 domain-containing protein | - |
| I5W22_RS04330 () | 881322..881972 | + | 651 | WP_002936498.1 | hypothetical protein | VF |
| I5W22_RS04335 () | 882005..883015 | - | 1011 | WP_011922483.1 | YdcF family protein | - |
| I5W22_RS04340 () | 883018..883791 | - | 774 | WP_011922484.1 | ribonuclease HII | - |
| I5W22_RS04345 () | 883778..884629 | - | 852 | WP_011922485.1 | GTPase Der | VF |
| I5W22_RS04350 () | 884729..885217 | - | 489 | WP_012775131.1 | YkgJ family cysteine cluster protein | - |
| I5W22_RS04355 () | 885269..885916 | - | 648 | WP_012775132.1 | Maf family protein | - |
| I5W22_RS04360 () | 885968..888112 | - | 2145 | WP_032498873.1 | hypothetical protein | VF |
| I5W22_RS04365 () | 888243..889514 | - | 1272 | WP_011922490.1 | dihydroorotase | - |
| I5W22_RS04370 () | 889554..890207 | - | 654 | WP_002939547.1 | uracil-DNA glycosylase | - |
| I5W22_RS04375 () | 890217..891143 | - | 927 | WP_012775134.1 | Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase | VF |
| I5W22_RS04380 () | 891252..891884 | - | 633 | WP_012775135.1 | orotate phosphoribosyltransferase | - |
| I5W22_RS04385 () | 892022..892348 | - | 327 | WP_011922495.1 | inorganic diphosphatase | - |
| I5W22_RS04390 () | 892341..893036 | - | 696 | WP_011922496.1 | orotidine-5'-phosphate decarboxylase | - |
| I5W22_RS04395 () | 893201..894142 | - | 942 | WP_012028173.1 | dihydroorotate dehydrogenase | - |
| I5W22_RS04400 () | 894152..895042 | - | 891 | WP_074390303.1 | dihydroorotate dehydrogenase electron transfer subunit | - |
| I5W22_RS04405 () | 895139..896050 | + | 912 | WP_012775137.1 | HTH-type transcriptional regulator HdfR | VF |
| I5W22_RS04410 () | 896214..897341 | + | 1128 | WP_011922500.1 | glucose-1-phosphate adenylyltransferase | - |
| I5W22_RS04415 () | 897354..898469 | + | 1116 | Protein_822 | glucose-1-phosphate adenylyltransferase subunit GlgD | - |
| I5W22_RS04420 () | 898478..899923 | + | 1446 | WP_011922502.1 | glycogen synthase GlgA | - |
| I5W22_RS04425 () | 899996..901834 | + | 1839 | WP_012775138.1 | 1,4-alpha-glucan branching protein GlgB | - |
| I5W22_RS04430 () | 901962..902762 | - | 801 | WP_011922504.1 | transporter substrate-binding domain-containing protein | - |
| I5W22_RS04435 () | 902934..903746 | - | 813 | WP_014636396.1 | transporter substrate-binding domain-containing protein | - |
| I5W22_RS04440 () | 903943..904287 | - | 345 | Protein_827 | 8-oxo-dGTP diphosphatase | - |
| I5W22_RS04445 () | 904397..905833 | - | 1437 | WP_044680665.1 | hypothetical protein ; Integrase | Integrase |
| I5W22_RS04450 () | 905826..907442 | - | 1617 | WP_044680666.1 | hypothetical protein ; Integrase | Integrase |
| I5W22_RS04455 () | 907442..909016 | - | 1575 | WP_044680668.1 | IS607 family transposase ISCbt3 | Transposase |
| I5W22_RS04460 () | 909115..909255 | - | 141 | WP_044680669.1 | hypothetical protein | - |
| I5W22_RS04465 () | 909531..909746 | - | 216 | WP_044680671.1 | helix-turn-helix domain-containing protein | - |
| I5W22_RS04470 () | 909825..910421 | - | 597 | WP_024394052.1 | response regulator transcription factor | - |
| I5W22_RS04475 () | 910402..911976 | - | 1575 | WP_024394053.1 | ATP-binding protein | - |
| I5W22_RS04480 () | 912063..914084 | - | 2022 | WP_104929696.1 | ABC transporter permease | - |
| I5W22_RS04485 () | 914096..914830 | - | 735 | WP_024394055.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| I5W22_RS04490 () | 915094..915270 | - | 177 | WP_024394056.1 | hypothetical protein | - |
| I5W22_RS04495 () | 915364..915546 | - | 183 | WP_024394057.1 | hypothetical protein | - |
| I5W22_RS04500 () | 915627..915812 | - | 186 | WP_024395819.1 | hypothetical protein | - |
| I5W22_RS04505 () | 917470..919587 | - | 2118 | WP_024394060.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| I5W22_RS04510 () | 919929..921157 | + | 1229 | Protein_841 | IS110 family transposase ISSpn10 | Transposase |
| I5W22_RS04515 () | 921281..924224 | - | 2944 | Protein_842 | type 2 lantipeptide synthetase LanM | - |
| I5W22_RS04520 () | 924356..926220 | - | 1865 | Protein_843 | relaxase/mobilization nuclease domain-containing protein | - |
| I5W22_RS04525 () | 926207..926572 | - | 366 | WP_044680677.1 | MobC family plasmid mobilization relaxosome protein | - |
| I5W22_RS04530 () | 926582..926941 | - | 360 | WP_044680678.1 | hypothetical protein | - |
| I5W22_RS04535 () | 927356..927568 | - | 213 | WP_162890955.1 | hypothetical protein | - |
| I5W22_RS04540 () | 927580..927759 | - | 180 | WP_012775540.1 | Blp family class II bacteriocin | - |
| I5W22_RS04545 () | 927957..928160 | - | 204 | Protein_848 | hypothetical protein | - |
| I5W22_RS04550 () | 928575..929267 | + | 693 | WP_197308483.1 | XRE family transcriptional regulator | - |
| I5W22_RS04555 () | 929410..930825 | + | 1416 | WP_197308484.1 | Y-family DNA polymerase | - |
| I5W22_RS04560 () | 930822..931172 | + | 351 | WP_197308503.1 | hypothetical protein | - |
| I5W22_RS04565 () | 931159..931467 | + | 309 | WP_197308485.1 | hypothetical protein | - |
| I5W22_RS04570 () | 931476..931772 | - | 297 | WP_044758818.1 | hypothetical protein | - |
| I5W22_RS04575 () | 931822..932211 | - | 390 | WP_002943340.1 | hypothetical protein | - |
| I5W22_RS04580 () | 932208..932435 | - | 228 | WP_002943342.1 | hypothetical protein | - |
| I5W22_RS04585 () | 932489..933565 | - | 1077 | WP_044758819.1 | toprim domain-containing protein | - |
| I5W22_RS04590 () | 933605..934243 | - | 639 | WP_050887020.1 | hypothetical protein | - |
| I5W22_RS04595 () | 934339..934629 | - | 291 | WP_105152240.1 | hypothetical protein | - |
| I5W22_RS04600 () | 934643..934942 | - | 300 | WP_002943350.1 | hypothetical protein | - |
| I5W22_RS04605 () | 935013..935972 | - | 960 | Protein_860 | hypothetical protein | - |
| I5W22_RS04610 () | 935965..936286 | - | 322 | Protein_861 | DUF4368 domain-containing protein | - |
| I5W22_RS04615 () | 936384..936653 | - | 270 | WP_002943355.1 | zeta toxin family protein | Toxin Detail |
| I5W22_RS04620 () | 936655..936927 | - | 273 | WP_002326825.1 | antitoxin | Antitoxin Detail |
| I5W22_RS04625 () | 936945..937154 | - | 210 | WP_000527318.1 | peptide-binding protein | - |
| I5W22_RS04630 () | 937238..938134 | - | 897 | WP_002326827.1 | ParA family protein | - |
| I5W22_RS04635 () | 938237..938497 | - | 261 | Protein_866 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
| I5W22_RS04640 () | 938667..939404 | - | 738 | WP_001038795.1 | Ribosomal RNA small subunit methyltransferase A | ARG |
| I5W22_RS04645 () | 939529..939612 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| I5W22_RS04650 () | 939661..939900 | - | 240 | WP_000635249.1 | peptide-binding protein | - |
| I5W22_RS04655 () | 939992..941092 | - | 1101 | Protein_870 | IS607 family transposase ISTsi1 | Transposase |
| I5W22_RS04660 () | 941146..941337 | - | 192 | WP_000503424.1 | hypothetical protein | - |
| I5W22_RS04665 () | 941408..941638 | - | 231 | WP_000659121.1 | hypothetical protein | - |
| I5W22_RS04670 () | 941810..943099 | + | 1290 | WP_197308486.1 | IS4 family transposase ISSsu2 | Transposase |
| I5W22_RS04675 () | 943324..943497 | - | 174 | WP_002779755.1 | cysteine-rich KTR domain-containing protein | - |
| I5W22_RS04680 () | 943549..945468 | - | 1920 | WP_014636291.1 | Peptide chain release factor 3 | VF |
| I5W22_RS04685 () | 945834..946208 | - | 375 | WP_024397218.1 | TnpV protein | - |
| I5W22_RS04690 () | 946189..952138 | - | 5950 | Protein_877 | N-6 DNA methylase | - |
| I5W22_RS04695 () | 952188..952739 | - | 552 | WP_105152238.1 | hypothetical protein | - |
| I5W22_RS04700 () | 952723..952914 | - | 192 | WP_001068448.1 | calcium-binding protein | - |
| I5W22_RS04705 () | 952915..957811 | - | 4897 | Protein_880 | hypothetical protein | VF |
| I5W22_RS04710 () | 957983..958573 | + | 591 | WP_105208272.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin Detail |
| I5W22_RS04715 () | 958570..959415 | + | 846 | WP_105208271.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin Detail |
| I5W22_RS04720 () | 959502..962279 | - | 2778 | WP_197308488.1 | CHAP domain-containing protein | - |
| I5W22_RS04725 () | 962281..964632 | - | 2352 | WP_197308489.1 | AAA family ATPase | - |
| I5W22_RS04730 () | 964589..964942 | - | 354 | WP_104929937.1 | PrgI family protein | - |
| I5W22_RS04735 () | 965133..965987 | - | 855 | WP_197308490.1 | conjugal transfer protein TrbL | - |
| I5W22_RS04740 () | 966006..966248 | - | 243 | WP_001072182.1 | hypothetical protein | - |
| I5W22_RS04745 () | 966266..968083 | - | 1818 | WP_197308491.1 | type IV secretory system conjugative DNA transfer family protein | - |
| I5W22_RS04750 () | 968083..968571 | - | 489 | WP_024392286.1 | hypothetical protein | - |
| I5W22_RS04755 () | 968649..969233 | - | 585 | WP_197308492.1 | CPBP family intramembrane metalloprotease | - |
| I5W22_RS04760 () | 969236..969469 | - | 234 | WP_001005709.1 | hypothetical protein | - |
| I5W22_RS04765 () | 969478..969861 | - | 384 | WP_197308493.1 | hypothetical protein | - |
| I5W22_RS04770 () | 969872..970300 | - | 429 | WP_197308494.1 | hypothetical protein | - |
| I5W22_RS04775 () | 970284..971639 | - | 1356 | WP_197308495.1 | DNA (cytosine-5-)-methyltransferase | - |
| I5W22_RS04780 () | 971789..972592 | - | 804 | WP_197308496.1 | replication initiator protein A | - |
| I5W22_RS04785 () | 972589..972762 | - | 174 | WP_197308497.1 | hypothetical protein | - |
| I5W22_RS04790 () | 972899..973054 | - | 156 | WP_024381332.1 | DNA mismatch repair protein MutT | - |
| I5W22_RS04795 () | 973047..973550 | - | 504 | WP_012028183.1 | GNAT family N-acetyltransferase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|