MGE detailed information

MGE type: Conjugative plasmid        MGE length: 108776 bp
Accession: NZ_CP064771        Location: 1..108776         Organism: Klebsiella pneumoniae subsp. pneumoniae strain HS20R14 isolate HS20R14       Replicon: plasmid pHS20R14-KPC-2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HS20R14_RS27210 (HS20R14_27155) 19..894 + 876 WP_004098982.1 replication initiation protein -
HS20R14_RS27215 (HS20R14_27160) 1543..2169 + 627 WP_004197649.1 Chromosome-partitioning ATPase Soj VF
HS20R14_RS27220 2166..2468 + 303 WP_004197636.1 hypothetical protein -
HS20R14_RS27225 (HS20R14_27170) 2916..3710 - 795 WP_004197635.1 site-specific integrase -
HS20R14_RS27230 (HS20R14_27175) 3908..4924 - 1017 WP_017899884.1 hypothetical protein -
HS20R14_RS27235 (HS20R14_27180) 4935..5249 - 315 WP_053389906.1 hypothetical protein -
HS20R14_RS27240 (HS20R14_27185) 5276..5671 - 396 WP_017899885.1 hypothetical protein -
HS20R14_RS27245 (HS20R14_27190) 5840..6145 - 306 WP_013023785.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
HS20R14_RS27250 (HS20R14_27195) 6147..6365 - 219 WP_001568025.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
HS20R14_RS27255 (HS20R14_27200) 6535..6996 - 462 WP_160880186.1 hypothetical protein -
HS20R14_RS27260 (HS20R14_27205) 6953..7183 + 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
HS20R14_RS27265 (HS20R14_27210) 7180..7596 + 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
HS20R14_RS27270 (HS20R14_27215) 7670..9232 + 1563 WP_004206609.1 AAA family ATPase -
HS20R14_RS27275 (HS20R14_27220) 9217..10239 + 1023 WP_000361404.1 helicase UvrD -
HS20R14_RS27280 (HS20R14_27225) 10495..11192 + 698 WP_223174630.1 IS1 family transposase ISKpn14 Transposase
HS20R14_RS27285 (HS20R14_27230) 11221..11493 + 273 Protein_15 IS5 family transposase ISPan1 Transposase
HS20R14_RS27290 (HS20R14_27235) 11773..12777 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
HS20R14_RS27295 (HS20R14_27240) 12856..13290 - 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
HS20R14_RS27300 (HS20R14_27245) 13362..13712 + 351 WP_001294663.1 mercuric transport protein MerT -
HS20R14_RS27305 (HS20R14_27250) 13726..14001 + 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
HS20R14_RS27310 (HS20R14_27255) 14037..14459 + 423 WP_001340589.1 organomercurial transporter MerC -
HS20R14_RS27315 (HS20R14_27260) 14511..16205 + 1695 WP_000105636.1 mercury(II) reductase -
HS20R14_RS27320 (HS20R14_27265) 16223..16585 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
HS20R14_RS27325 (HS20R14_27270) 16582..16818 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
HS20R14_RS27330 (HS20R14_27275) 16854..17522 + 669 WP_001300294.1 putative signaling protein VF
HS20R14_RS27335 (HS20R14_27280) 17597..18847 + 1251 Protein_25 transposase -
HS20R14_RS27340 (HS20R14_27285) 18912..19616 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HS20R14_RS27345 (HS20R14_27290) 19668..20129 + 462 Protein_27 Tn3 family transposase TnpR_Tn3 Transposase
HS20R14_RS27350 (HS20R14_27295) 20252..21232 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
HS20R14_RS27355 (HS20R14_27300) 21508..22389 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
HS20R14_RS27360 (HS20R14_27305) 22639..23520 - 882 Protein_30 IS1182 family transposase ISKpn6 Transposase
HS20R14_RS27365 (HS20R14_27310) 23624..23920 - 297 WP_013213987.1 transcriptional regulator -
HS20R14_RS27370 (HS20R14_27315) 23966..24121 - 156 WP_013213988.1 hypothetical protein -
HS20R14_RS27375 (HS20R14_27320) 24249..24674 - 426 WP_013213989.1 antirestriction protein -
HS20R14_RS27380 (HS20R14_27325) 24785..25063 - 279 WP_013213990.1 hypothetical protein -
HS20R14_RS27385 (HS20R14_27330) 25597..26208 - 612 Protein_35 replication protein -
HS20R14_RS27390 (HS20R14_27335) 26272..26976 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HS20R14_RS27395 (HS20R14_27340) 27028..27489 + 462 Protein_37 Tn3 family transposase TnpR_Tn3 Transposase
HS20R14_RS27400 (HS20R14_27345) 27612..28592 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
HS20R14_RS27405 (HS20R14_27350) 28868..29749 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
HS20R14_RS27410 (HS20R14_27355) 29999..30880 - 882 Protein_40 IS1182 family transposase ISKpn6 Transposase
HS20R14_RS27415 (HS20R14_27360) 30984..31280 - 297 WP_013213987.1 transcriptional regulator -
HS20R14_RS27420 (HS20R14_27365) 31326..31481 - 156 WP_013213988.1 hypothetical protein -
HS20R14_RS27425 (HS20R14_27370) 31609..32034 - 426 WP_013213989.1 antirestriction protein -
HS20R14_RS27430 (HS20R14_27375) 32145..32423 - 279 WP_013213990.1 hypothetical protein -
HS20R14_RS27435 (HS20R14_27380) 32957..33568 - 612 Protein_45 replication protein -
HS20R14_RS27440 (HS20R14_27385) 33632..34336 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HS20R14_RS27445 (HS20R14_27390) 34388..34849 + 462 Protein_47 Tn3 family transposase TnpR_Tn3 Transposase
HS20R14_RS27450 (HS20R14_27395) 34972..35952 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
HS20R14_RS27455 (HS20R14_27400) 36228..37109 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
HS20R14_RS27460 (HS20R14_27405) 37359..38240 - 882 Protein_50 IS1182 family transposase ISKpn6 Transposase
HS20R14_RS27465 (HS20R14_27410) 38344..38640 - 297 WP_013213987.1 transcriptional regulator -
HS20R14_RS27470 (HS20R14_27415) 38686..38841 - 156 WP_013213988.1 hypothetical protein -
HS20R14_RS27475 (HS20R14_27420) 38969..39394 - 426 WP_013213989.1 antirestriction protein -
HS20R14_RS27480 (HS20R14_27425) 39505..39783 - 279 WP_013213990.1 hypothetical protein -
HS20R14_RS27485 (HS20R14_27430) 40317..40934 - 618 Protein_55 replication protein -
HS20R14_RS27490 (HS20R14_27435) 41326..41886 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
HS20R14_RS27495 (HS20R14_27440) 41890..44856 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
HS20R14_RS27500 (HS20R14_27445) 44890..45192 + 303 Protein_58 IS6 family transposase IS26 Transposase
HS20R14_RS27505 (HS20R14_27450) 45394..45867 - 474 WP_013213991.1 GNAT family N-acetyltransferase -
HS20R14_RS27510 (HS20R14_27455) 46287..46799 - 513 Protein_60 ISL3 family transposase ISEc38 Transposase
HS20R14_RS27515 (HS20R14_27460) 46803..47135 - 333 WP_013213994.1 hypothetical protein -
HS20R14_RS27520 (HS20R14_27465) 47521..48432 - 912 WP_013213995.1 hypothetical protein -
HS20R14_RS27525 (HS20R14_27470) 48484..50426 - 1943 Protein_63 hypothetical protein -
HS20R14_RS27530 (HS20R14_27475) 50430..51323 - 894 WP_013213999.1 hypothetical protein -
HS20R14_RS27535 (HS20R14_27480) 51331..52572 - 1242 WP_013213998.1 N-6 DNA methylase -
HS20R14_RS27540 (HS20R14_27485) 53892..54767 - 876 WP_072101968.1 incFII family plasmid replication initiator RepA -
HS20R14_RS27545 (HS20R14_27495) 55065..55322 - 258 WP_015344940.1 replication regulatory protein RepA -
HS20R14_RS27550 (HS20R14_27500) 55454..56005 - 552 WP_015344941.1 Phospholipase D VF
HS20R14_RS27555 (HS20R14_27505) 56109..56417 - 309 WP_004152383.1 hypothetical protein -
HS20R14_RS27560 (HS20R14_27510) 56414..57064 - 651 WP_014343480.1 DUF2726 domain-containing protein -
HS20R14_RS27565 (HS20R14_27515) 57120..57764 - 645 WP_004153014.1 hypothetical protein -
HS20R14_RS27570 (HS20R14_27520) 57814..58416 - 603 WP_013023836.1 PIN domain-containing protein -
HS20R14_RS27575 (HS20R14_27525) 58577..59170 - 594 WP_004152380.1 fertility inhibition protein FinO -
HS20R14_RS27580 (HS20R14_27530) 59242..59967 - 726 WP_014386207.1 type-F conjugative transfer system pilin acetylase TraX -
HS20R14_RS27585 (HS20R14_27535) 60012..65270 - 5259 WP_014386206.1 Multifunctional conjugation protein TraI Relaxase
HS20R14_RS27590 (HS20R14_27540) 65270..67579 - 2310 WP_014386205.1 type IV conjugative transfer system coupling protein TraD -
HS20R14_RS27595 (HS20R14_27545) 67706..68395 - 690 WP_013023831.1 hypothetical protein -
HS20R14_RS27600 (HS20R14_27550) 68588..69319 - 732 WP_013214036.1 conjugal transfer complement resistance protein TraT -
HS20R14_RS27605 (HS20R14_27555) 69570..70172 - 603 WP_013214035.1 conjugal transfer protein TraS -
HS20R14_RS27610 (HS20R14_27560) 70195..73017 - 2823 WP_013214034.1 conjugal transfer mating-pair stabilization protein TraG -
HS20R14_RS27615 (HS20R14_27565) 73017..74396 - 1380 WP_072157884.1 conjugal transfer pilus assembly protein TraH -
HS20R14_RS27620 (HS20R14_27570) 74374..74817 - 444 WP_013214032.1 F-type conjugal transfer protein TrbF -
HS20R14_RS27625 (HS20R14_27575) 74863..75420 - 558 WP_013214031.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
HS20R14_RS27630 (HS20R14_27580) 75392..75631 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
HS20R14_RS27635 (HS20R14_27585) 75642..76394 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
HS20R14_RS27640 (HS20R14_27590) 76415..76741 - 327 WP_004152676.1 hypothetical protein -
HS20R14_RS27645 (HS20R14_27595) 76754..77002 - 249 WP_004152675.1 hypothetical protein -
HS20R14_RS27650 (HS20R14_27600) 76980..77234 - 255 WP_004152674.1 conjugal transfer protein TrbE -
HS20R14_RS27655 (HS20R14_27605) 77266..79221 - 1956 WP_030003482.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
HS20R14_RS27660 (HS20R14_27610) 79280..79918 - 639 WP_069985712.1 type-F conjugative transfer system pilin assembly protein TrbC -
HS20R14_RS27665 (HS20R14_27615) 79931..80920 - 990 WP_029497420.1 conjugal transfer pilus assembly protein TraU -
HS20R14_RS27670 (HS20R14_27620) 80917..81318 - 402 WP_004194979.1 hypothetical protein -
HS20R14_RS27675 (HS20R14_27625) 81353..81988 - 636 WP_029497419.1 type-F conjugative transfer system protein TraW -
HS20R14_RS27680 (HS20R14_27630) 81988..82377 - 390 WP_004167468.1 type-F conjugative transfer system protein TrbI -
HS20R14_RS27685 (HS20R14_27635) 82377..85016 - 2640 WP_013214024.1 type IV secretion system protein TraC -
HS20R14_RS27690 (HS20R14_27640) 85088..85486 - 399 WP_023179972.1 hypothetical protein -
HS20R14_RS27695 (HS20R14_27645) 85865..86269 - 405 WP_004197817.1 hypothetical protein -
HS20R14_RS27700 (HS20R14_27650) 86336..86647 - 312 WP_029497417.1 hypothetical protein -
HS20R14_RS27705 (HS20R14_27655) 86648..86866 - 219 WP_004195468.1 hypothetical protein -
HS20R14_RS27710 (HS20R14_27660) 87189..87773 - 585 WP_032440547.1 type IV conjugative transfer system lipoprotein TraV -
HS20R14_RS27715 (HS20R14_27665) 87846..89270 - 1425 WP_004194260.1 F-type conjugal transfer pilus assembly protein TraB -
HS20R14_RS27720 (HS20R14_27670) 89270..90010 - 741 WP_013023821.1 type-F conjugative transfer system secretin TraK -
HS20R14_RS27725 (HS20R14_27675) 89997..90563 - 567 WP_004144423.1 type IV conjugative transfer system protein TraE -
HS20R14_RS27730 (HS20R14_27680) 90583..90888 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
HS20R14_RS27735 (HS20R14_27685) 90902..91270 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
HS20R14_RS27900 (HS20R14_27690) 91339..91539 - 201 WP_004194116.1 TraY domain-containing protein -
HS20R14_RS27740 (HS20R14_27695) 91625..92326 - 702 WP_004194113.1 hypothetical protein -
HS20R14_RS27745 (HS20R14_27700) 92556..92948 - 393 WP_004194114.1 conjugal transfer relaxosome DNA-binding protein TraM -
HS20R14_RS27750 (HS20R14_27705) 93380..93865 + 486 WP_032440470.1 hypothetical protein VF
HS20R14_RS27755 (HS20R14_27710) 93898..94227 - 330 WP_071994324.1 DUF5983 family protein -
HS20R14_RS27760 (HS20R14_27715) 94260..95081 - 822 WP_023287138.1 DUF932 domain-containing protein -
HS20R14_RS27765 (HS20R14_27720) 95906..96469 - 564 WP_004152756.1 methyltransferase -
HS20R14_RS27770 (HS20R14_27725) 96517..97872 - 1356 WP_013054814.1 DUF3560 domain-containing protein -
HS20R14_RS27775 (HS20R14_27730) 97924..98154 - 231 WP_001568051.1 hypothetical protein -
HS20R14_RS27780 (HS20R14_27735) 98246..98473 - 228 WP_001568050.1 hypothetical protein -
HS20R14_RS27785 (HS20R14_27740) 99211..99531 - 321 WP_032436760.1 hypothetical protein -
HS20R14_RS27790 (HS20R14_27745) 99566..99820 - 255 WP_011977779.1 DNA polymerase III subunit theta -
HS20R14_RS27795 (HS20R14_27750) 100008..100199 - 192 WP_001568047.1 hypothetical protein -
HS20R14_RS27800 (HS20R14_27755) 100242..100748 - 507 WP_013214014.1 antirestriction protein ArdA -
HS20R14_RS27805 (HS20R14_27760) 100791..101219 - 429 WP_001568045.1 antirestriction protein -
HS20R14_RS27810 (HS20R14_27765) 101900..102667 - 768 WP_013214013.1 hypothetical protein -
HS20R14_RS27815 (HS20R14_27770) 102721..103140 - 420 WP_001568043.1 DUF1380 domain-containing protein -
HS20R14_RS27820 (HS20R14_27775) 103150..103371 - 222 WP_001568042.1 hypothetical protein -
HS20R14_RS27825 (HS20R14_27780) 103371..104072 - 702 WP_001568041.1 DNA methylase -
HS20R14_RS27830 104144..104313 - 170 Protein_125 hypothetical protein -
HS20R14_RS27835 (HS20R14_27785) 104509..104739 - 231 WP_001568040.1 hypothetical protein -
HS20R14_RS27840 (HS20R14_27790) 104802..105473 - 672 WP_013214012.1 plasmid partitioning/stability family protein -
HS20R14_RS27845 (HS20R14_27795) 105476..106447 - 972 WP_004152353.1 plasmid segregation protein ParM -
HS20R14_RS27850 (HS20R14_27800) 106681..107112 + 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
HS20R14_RS27855 (HS20R14_27805) 107112..108383 + 1272 WP_004197646.1 Y-family DNA polymerase -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance