NZ_CP0642481..168025

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 168025 bp
Accession: NZ_CP064248        Location: 1..168025         Organism: Klebsiella pneumoniae strain JX-CR-hvKP-2       Replicon: plasmid pJX2-2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS498_RS28515 () 308..538 + 231 WP_001736714.1 hypothetical protein -
- () 739..798 - 60 NuclAT_1 - Antitoxin Detail
- () 739..798 - 60 NuclAT_1 - Antitoxin Detail
- () 739..798 - 60 NuclAT_1 - Antitoxin Detail
- () 739..798 - 60 NuclAT_1 - Antitoxin Detail
IS498_RS28520 () 843..992 + 150 WP_001312851.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
IS498_RS28525 () 1276..1524 + 249 WP_000083837.1 replication regulatory protein RepA -
IS498_RS28530 () 1769..1843 + 75 WP_001375168.1 RepA leader peptide Tap -
IS498_RS28535 () 1836..2693 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
IS498_RS28540 () 3632..4285 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
IS498_RS28545 () 4378..4635 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
IS498_RS28550 () 4568..4969 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
IS498_RS28555 () 5218..5633 + 416 Protein_9 IS1 family transposase -
IS498_RS28560 () 5669..6214 - 546 Protein_10 Tn3 family transposase TnpA_Tn3 Transposase
IS498_RS28565 () 6280..6984 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS28570 () 7054..7245 + 192 Protein_12 transposase -
IS498_RS28575 () 7495..8370 + 876 WP_013188475.1 hypothetical protein ARG
IS498_RS28580 () 8405..9373 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
IS498_RS28585 () 9430..10527 + 1098 Protein_15 TonB-dependent receptor -
IS498_RS28590 () 10595..11044 - 450 Protein_16 PAS domain-containing protein -
IS498_RS28595 () 11124..11828 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS28600 () 11893..12483 + 591 Protein_18 IS91 family transposase ISSbo1 Transposase
IS498_RS28605 () 12939..13643 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS28610 () 13709..14227 + 519 WP_014839979.1 hypothetical protein -
IS498_RS28615 () 14232..14648 - 417 WP_014839980.1 Metallothiol transferase FosB ARG
IS498_RS28620 () 15034..15738 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS28625 () 15789..16406 - 618 Protein_23 IS91 family transposase ISSbo1 Transposase
IS498_RS28630 () 16416..16604 - 189 WP_000957857.1 hypothetical protein -
IS498_RS28635 () 16696..17232 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
IS498_RS28640 () 17415..18275 + 861 WP_000027057.1 hypothetical protein ARG
IS498_RS28645 () 18445..19200 + 756 WP_012372818.1 hypothetical protein ARG
IS498_RS28650 () 19281..19562 - 282 WP_015059004.1 sodium/hydrogen exchanger -
IS498_RS28655 () 19650..20354 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
IS498_RS28660 () 20345..20485 + 141 WP_071557810.1 hypothetical protein -
IS498_RS28665 () 21934..22168 + 235 Protein_31 type II toxin-antitoxin system RelE/ParE family toxin -
IS498_RS28670 () 22296..22577 + 282 WP_001333089.1 hypothetical protein -
IS498_RS28675 () 22700..23050 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
IS498_RS28680 () 23053..24015 - 963 WP_000959884.1 plasmid segregation protein ParM -
IS498_RS28685 () 24162..24455 + 294 WP_032146011.1 hypothetical protein -
IS498_RS28690 () 24532..25215 + 684 WP_000085883.1 DNA methylase -
IS498_RS28695 () 25216..25437 + 222 WP_001104881.1 hypothetical protein -
IS498_RS28700 () 25451..25885 + 435 WP_000274503.1 DUF1380 family protein -
IS498_RS28705 () 25936..26712 + 777 WP_001383963.1 hypothetical protein -
IS498_RS28710 () 27130..27555 + 426 WP_001198928.1 antirestriction protein -
IS498_RS28715 () 27602..28024 + 423 WP_000271762.1 DUF1380 family protein -
IS498_RS28720 () 28021..28212 + 192 WP_001027493.1 hypothetical protein -
IS498_RS28725 () 28526..30193 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
IS498_RS28730 () 31593..31823 + 231 WP_000218642.1 hypothetical protein -
IS498_RS28735 () 31875..33236 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
IS498_RS28740 () 33283..33846 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
IS498_RS28745 () 34689..35216 + 528 WP_000290834.1 single-stranded DNA-binding protein -
IS498_RS28750 () 35274..35507 + 234 WP_000006003.1 DUF905 family protein -
IS498_RS28755 () 35568..37591 + 2024 Protein_49 ParB/RepB/Spo0J family partition protein -
IS498_RS28760 () 37660..38094 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
IS498_RS28765 () 38091..38810 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- () 38822..39046 + 225 NuclAT_0 - Antitoxin Detail
- () 38822..39046 + 225 NuclAT_0 - Antitoxin Detail
- () 38822..39046 + 225 NuclAT_0 - Antitoxin Detail
- () 38822..39046 + 225 NuclAT_0 - Antitoxin Detail
IS498_RS28770 () 39090..39248 + 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
IS498_RS28775 () 39486..39863 - 378 Protein_53 hypothetical protein -
IS498_RS28780 () 40163..40459 + 297 WP_001272251.1 hypothetical protein -
IS498_RS28785 () 40570..41391 + 822 WP_001234445.1 DUF945 domain-containing protein -
IS498_RS28790 () 41688..42335 - 648 WP_015059008.1 hypothetical protein VF
IS498_RS28795 () 42612..42995 + 384 WP_000124981.1 relaxosome protein TraM -
IS498_RS28800 () 43186..43872 + 687 WP_015059009.1 PAS domain-containing protein -
IS498_RS28805 () 43966..44193 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
IS498_RS28810 () 44227..44592 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
IS498_RS28815 () 44607..44918 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
IS498_RS28820 () 44940..45506 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
IS498_RS28825 () 45517..46221 + 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
IS498_RS28830 () 46221..47648 + 1428 WP_032297072.1 conjugal transfer protein TraB -
IS498_RS28835 () 47638..48228 + 591 WP_000002778.1 conjugal transfer protein TraP -
IS498_RS28840 () 48182..48412 + 231 WP_001352845.1 conjugal transfer protein TrbD -
IS498_RS28845 () 48424..48675 + 252 WP_001038341.1 conjugal transfer protein TrbG -
IS498_RS28850 () 48672..49187 + 516 WP_062955122.1 type IV conjugative transfer system lipoprotein TraV -
IS498_RS28855 () 49322..49543 + 222 WP_001278692.1 conjugal transfer protein TraR -
IS498_RS28860 () 49703..52330 + 2628 WP_015059012.1 type IV secretion system protein TraC -
IS498_RS28865 () 52327..52713 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
IS498_RS28870 () 52710..53342 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
IS498_RS28875 () 53339..54331 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
IS498_RS28880 () 54358..54666 + 309 WP_000412447.1 hypothetical protein -
IS498_RS28885 () 54729..55250 + 522 WP_015059014.1 hypothetical protein -
IS498_RS28890 () 55277..55915 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
IS498_RS28895 () 55912..56283 + 372 WP_000056336.1 hypothetical protein -
IS498_RS28900 () 56309..56731 + 423 WP_001229309.1 HNH endonuclease -
IS498_RS28905 () 56728..58578 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
IS498_RS28910 () 58605..58862 + 258 WP_053913405.1 conjugal transfer protein TrbE -
IS498_RS28915 () 58849..59598 + 750 WP_072354014.1 type-F conjugative transfer system pilin assembly protein TraF -
IS498_RS28920 () 59714..59995 + 282 WP_000549793.1 type-F conjugative transfer system pilin chaperone TraQ -
IS498_RS28925 () 59982..60527 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
IS498_RS28930 () 60457..60831 + 375 WP_071776752.1 P-type conjugative transfer protein TrbJ -
IS498_RS28935 () 60785..61177 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
IS498_RS28940 () 61164..62537 + 1374 WP_000944325.1 conjugal transfer protein TraH -
IS498_RS28945 () 62534..65350 + 2817 WP_015059018.1 conjugal transfer mating pair stabilization protein TraG -
IS498_RS28950 () 65383..65904 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
IS498_RS28955 () 65929..66660 + 732 WP_021559024.1 complement resistance protein TraT -
IS498_RS28960 () 66863..67600 + 738 WP_015059020.1 hypothetical protein -
IS498_RS28965 () 67651..69876 + 2226 WP_000009363.1 type IV conjugative transfer system coupling protein TraD -
IS498_RS28970 () 69876..75011 + 5136 WP_071177725.1 ATP-dependent RecD-like DNA helicase Relaxase
IS498_RS28975 () 75045..75749 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS28980 () 75887..76768 + 882 Protein_94 IS1182 family transposase ISKpn6 Transposase
IS498_RS28985 () 77018..77899 - 882 WP_004199234.1 hypothetical protein ARG
IS498_RS28990 () 78175..79155 - 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
IS498_RS28995 () 79278..79739 - 462 Protein_97 Tn3 family transposase TnpR_Tn3 Transposase
IS498_RS29000 () 79791..80495 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS29005 () 80560..81732 - 1173 Protein_99 transposase -
IS498_RS29010 () 81807..82475 - 669 WP_001300294.1 hypothetical protein VF
IS498_RS29015 () 82511..82747 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
IS498_RS29020 () 82744..83106 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
IS498_RS29025 () 83124..84818 - 1695 WP_000105636.1 mercury(II) reductase -
IS498_RS29030 () 84870..85292 - 423 WP_001340589.1 organomercurial transporter MerC -
IS498_RS29035 () 85328..85603 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
IS498_RS29040 () 85617..85967 - 351 WP_001294663.1 mercuric transport protein MerT -
IS498_RS29045 () 86039..86473 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
IS498_RS29050 () 86552..87556 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
IS498_RS29055 () 87836..88108 - 273 Protein_109 transposase -
IS498_RS29060 () 88137..88834 - 698 Protein_110 IS1 family transposase ISKpn14 Transposase
IS498_RS29065 () 89090..90112 - 1023 WP_000361404.1 helicase UvrD -
IS498_RS29070 () 90097..91659 - 1563 WP_004206609.1 AAA family ATPase -
IS498_RS29075 () 91733..92149 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
IS498_RS29080 () 92146..92376 - 231 WP_001261282.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
IS498_RS29085 () 92333..92794 + 462 WP_014343465.1 hypothetical protein -
IS498_RS29090 () 92955..93899 + 945 WP_011977810.1 hypothetical protein -
IS498_RS29095 () 93936..94328 + 393 WP_011977811.1 hypothetical protein -
IS498_RS29100 () 94386..94907 + 522 WP_013214008.1 hypothetical protein -
IS498_RS29105 () 94953..95156 + 204 WP_011977813.1 hypothetical protein -
IS498_RS29110 () 95186..96190 + 1005 WP_011977814.1 hypothetical protein -
IS498_RS29115 () 96374..97153 + 780 WP_013214009.1 site-specific integrase -
IS498_RS29120 () 97199..97456 - 258 WP_013214010.1 hypothetical protein -
IS498_RS29125 () 97585..97698 - 114 WP_014343462.1 hypothetical protein -
IS498_RS29130 () 98234..99100 + 867 WP_004118283.1 replication initiation protein -
IS498_RS29135 () 100210..101415 + 1206 WP_011977818.1 AAA family ATPase -
IS498_RS29140 () 101415..102389 + 975 WP_011977819.1 ParB/RepB/Spo0J family partition protein -
IS498_RS29145 () 102471..103742 - 1272 WP_013214011.1 Y-family DNA polymerase -
IS498_RS29150 () 103742..104173 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
IS498_RS29155 () 104581..106068 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
IS498_RS29160 () 106317..107288 + 972 WP_004152353.1 mediator of plasmid stability -
IS498_RS29165 () 107291..107962 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
IS498_RS29170 () 108025..108255 + 231 WP_001568040.1 hypothetical protein -
IS498_RS29175 () 108692..109393 + 702 WP_001568041.1 DNA methylase -
IS498_RS29180 () 109393..109614 + 222 WP_001568042.1 hypothetical protein -
IS498_RS29185 () 109624..110043 + 420 WP_001568043.1 DUF1380 domain-containing protein -
IS498_RS29190 () 110097..110864 + 768 WP_013214013.1 hypothetical protein -
IS498_RS29195 () 111545..111973 + 429 WP_001568045.1 antirestriction protein -
IS498_RS29200 () 112016..112522 + 507 WP_013214014.1 antirestriction protein ArdA -
IS498_RS29205 () 112565..112756 + 192 WP_001568047.1 hypothetical protein -
IS498_RS29210 () 112944..113198 + 255 WP_011977779.1 DNA polymerase III subunit theta -
IS498_RS29215 () 113233..113553 + 321 WP_001568049.1 hypothetical protein -
IS498_RS29220 () 114233..114460 + 228 WP_001568050.1 hypothetical protein -
IS498_RS29225 () 114552..114782 + 231 WP_001568051.1 hypothetical protein -
IS498_RS29230 () 114834..116189 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
IS498_RS29235 () 116237..116800 + 564 WP_014343514.1 methyltransferase -
IS498_RS29240 () 117633..118175 + 543 WP_014343512.1 single-stranded DNA-binding protein -
IS498_RS29245 () 118224..118472 + 249 WP_001568055.1 DUF905 domain-containing protein -
IS498_RS29250 () 118542..120599 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
IS498_RS29255 () 120644..121075 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
IS498_RS29260 () 121072..121800 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
IS498_RS29265 () 121797..122123 + 327 WP_013023807.1 hypothetical protein -
IS498_RS29270 () 122179..122553 + 375 WP_014343510.1 hypothetical protein -
IS498_RS29275 () 122781..122939 + 159 WP_014343509.1 type I toxin-antitoxin system Hok family toxin -
IS498_RS29280 () 123632..123904 + 273 WP_040245921.1 hypothetical protein -
IS498_RS29285 () 123901..124251 + 351 WP_040245917.1 hypothetical protein -
IS498_RS29290 () 124266..124583 + 318 WP_014343505.1 hypothetical protein -
IS498_RS29295 () 125424..125780 + 357 WP_014343501.1 hypothetical protein -
IS498_RS29300 () 125841..126053 + 213 WP_014343500.1 hypothetical protein -
IS498_RS29305 () 126064..126288 + 225 WP_014343499.1 hypothetical protein -
IS498_RS29310 () 126369..126689 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
IS498_RS29315 () 126679..126957 + 279 WP_004152721.1 helix-turn-helix domain-containing protein -
IS498_RS29320 () 127894..128715 + 822 WP_004152492.1 DUF945 domain-containing protein -
IS498_RS29325 () 128748..129077 + 330 WP_013214015.1 hypothetical protein -
IS498_RS29330 () 129110..129595 - 486 WP_014343495.1 hypothetical protein VF
IS498_RS29335 () 129986..130402 + 417 WP_014343494.1 relaxosome protein TraM -
IS498_RS29340 () 130602..131339 + 738 WP_013214018.1 conjugal transfer protein TrbJ -
IS498_RS29345 () 131454..131660 + 207 WP_171773970.1 TraY domain-containing protein -
IS498_RS29350 () 131722..132090 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
IS498_RS29355 () 132104..132409 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
IS498_RS29360 () 132429..132794 + 366 Protein_170 type IV conjugative transfer system protein TraE -
IS498_RS29365 () 132849..133553 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS29370 () 133679..134053 - 375 WP_008324180.1 hypothetical protein -
IS498_RS29375 () 134679..135038 - 360 WP_015493069.1 hypothetical protein -
IS498_RS29380 () 135100..135423 - 324 WP_008324183.1 hypothetical protein -
IS498_RS29385 () 135420..136148 - 729 WP_008324185.1 plasmid SOS inhibition protein A -
IS498_RS29390 () 136145..136576 - 432 WP_008324186.1 conjugation system SOS inhibitor PsiB -
IS498_RS29395 () 136619..138628 - 2010 Protein_177 ParB/RepB/Spo0J family partition protein -
IS498_RS29400 () 138699..138929 - 231 WP_015493071.1 DUF905 domain-containing protein -
IS498_RS29405 () 139555..139872 - 318 Protein_179 hypothetical protein -
IS498_RS29410 () 139907..140161 - 255 WP_015493072.1 DNA polymerase III subunit theta -
IS498_RS29415 () 140354..140545 - 192 WP_015493073.1 hypothetical protein -
IS498_RS29420 () 140588..141094 - 507 WP_015493074.1 antirestriction protein ArdA -
IS498_RS29425 () 141499..142278 - 780 WP_015493075.1 hypothetical protein -
IS498_RS29430 () 142332..142751 - 420 WP_015493076.1 DUF1380 domain-containing protein -
IS498_RS29435 () 142762..142983 - 222 WP_015493077.1 hypothetical protein -
IS498_RS29440 () 142983..143660 - 678 WP_002211749.1 DNA methylase -
IS498_RS29445 () 144019..144690 + 672 WP_015493079.1 SOS response-associated peptidase family protein -
IS498_RS29450 () 144870..145292 + 423 WP_015493080.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
IS498_RS29455 () 145292..146563 + 1272 WP_015493081.1 Y-family DNA polymerase -
IS498_RS29460 () 146699..147670 - 972 WP_016479949.1 ParB/RepB/Spo0J family partition protein -
IS498_RS29465 () 147667..148872 - 1206 WP_015493083.1 Plasmid partition protein A VF
IS498_RS29470 () 149235..149867 + 633 WP_022652286.1 Tn3 family transposase TnpR_TnEc1 Transposase
IS498_RS29475 () 149921..150121 + 201 WP_040219232.1 hypothetical protein -
IS498_RS29480 () 150268..151218 + 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
IS498_RS29485 () 151215..151826 - 612 WP_015493086.1 DUF2913 family protein -
IS498_RS29490 () 151823..152218 - 396 WP_015493087.1 hypothetical protein -
IS498_RS29495 () 152271..152663 - 393 Protein_197 3'-5' exonuclease -
IS498_RS29500 () 152732..153712 + 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
IS498_RS29505 () 153859..154236 + 378 Protein_199 restriction endonuclease -
IS498_RS29510 () 154364..154921 + 558 WP_042934582.1 hypothetical protein -
IS498_RS29515 () 155390..156094 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS29520 () 156227..156868 - 642 WP_001011939.1 Chloramphenicol acetyltransferase 2 ARG
IS498_RS29525 () 157018..157518 - 501 WP_001239317.1 hypothetical protein -
IS498_RS29530 () 157598..158302 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS29535 () 158308..158448 + 141 WP_001044210.1 hypothetical protein -
IS498_RS29540 () 158934..159671 + 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
IS498_RS29545 () 159668..159892 + 225 WP_000743213.1 hypothetical protein -
IS498_RS29550 () 160014..160190 + 177 WP_000954592.1 Arm DNA-binding domain-containing protein -
IS498_RS29555 () 160372..161376 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
IS498_RS29560 () 161455..164421 - 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
IS498_RS29565 () 164424..164489 - 66 Protein_211 helix-turn-helix domain-containing protein -
IS498_RS29570 () 164542..165246 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS498_RS29575 () 165310..165471 + 162 Protein_213 DNA helicase -
IS498_RS29580 () 165491..166237 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
IS498_RS29585 () 166292..166852 + 561 WP_000139328.1 fertility inhibition protein FinO -
IS498_RS29590 () 166984..167184 + 201 WP_015059022.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance