MGE detailed information
MGE type: Conjugative plasmid MGE length: 140376 bp
Accession: NZ_CP060980 Location: 1..140376 Organism: Escherichia coli strain EC3 Replicon: plasmid pEC3-2
Accession: NZ_CP060980 Location: 1..140376 Organism: Escherichia coli strain EC3 Replicon: plasmid pEC3-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H9191_RS22860 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H9191_RS22865 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| H9191_RS22870 (2124) | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| H9191_RS22875 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | antimicrobial resistance protein Mig-14 | - |
| H9191_RS22880 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| H9191_RS22885 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | omptin family outer membrane protease | - |
| H9191_RS22890 (6256) | 6256..6645 | + | 390 | WP_032145261.1 | hypothetical protein | - |
| H9191_RS22895 (7449) | 7449..7628 | - | 180 | Protein_7 | integrase core domain-containing protein | - |
| H9191_RS22900 (7767) | 7767..8966 | + | 1200 | Protein_8 | IS3 family transposase | - |
| H9191_RS22905 (9114) | 9114..9439 | - | 326 | Protein_9 | integrase core domain-containing protein | - |
| H9191_RS22910 (9485) | 9485..9825 | + | 341 | Protein_10 | IS3 family transposase | - |
| H9191_RS22915 (10420) | 10420..11607 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| H9191_RS22920 (11604) | 11604..13544 | + | 1941 | WP_000733250.1 | MacB family efflux pump subunit | - |
| H9191_RS22925 (13548) | 13548..14918 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| H9191_RS22930 (15392) | 15392..15586 | + | 195 | Protein_14 | IS200/IS605-like element IS200C family transposase | - |
| H9191_RS22935 (15715) | 15715..16656 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| H9191_RS22940 (16891) | 16891..18280 | - | 1390 | Protein_16 | ISNCY family transposase | - |
| H9191_RS22945 (18590) | 18590..18739 | - | 150 | Protein_17 | IS3 family transposase | - |
| H9191_RS22950 (18917) | 18917..20110 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| H9191_RS22955 (21333) | 21333..22569 | - | 1237 | Protein_19 | IS3 family transposase | - |
| H9191_RS22960 (23196) | 23196..23489 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| H9191_RS22970 (23547) | 23547..23746 | - | 200 | Protein_21 | lysis protein | - |
| H9191_RS22975 (24300) | 24300..25325 | + | 1026 | Protein_22 | integrase core domain-containing protein | - |
| H9191_RS22980 (25587) | 25587..26702 | + | 1116 | WP_001318220.1 | salmochelin biosynthesis C-glycosyltransferase IroB | - |
| H9191_RS22985 (26842) | 26842..30501 | + | 3660 | WP_001111199.1 | salmochelin/enterobactin export ABC transporter IroC | - |
| H9191_RS22990 (30605) | 30605..31834 | + | 1230 | WP_000933675.1 | catecholate siderophore esterase IroD | - |
| H9191_RS22995 (31919) | 31919..32875 | + | 957 | WP_064055648.1 | catecholate siderophore esterase IroE | - |
| H9191_RS23000 (32920) | 32920..35097 | - | 2178 | WP_001222186.1 | siderophore salmochelin receptor IroN | - |
| H9191_RS23005 (35332) | 35332..36029 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| H9191_RS23010 (36046) | 36046..36243 | - | 198 | Protein_29 | colicin V | - |
| H9191_RS23015 (36221) | 36221..36457 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| H9191_RS23020 (36999) | 36999..37202 | - | 204 | Protein_31 | hypothetical protein | - |
| H9191_RS23025 (37375) | 37375..37542 | + | 168 | Protein_32 | colicin-B | - |
| H9191_RS23030 (37560) | 37560..38087 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| H9191_RS23035 (38331) | 38331..39146 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| H9191_RS23040 (39196) | 39196..39549 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| H9191_RS23045 (39727) | 39727..40518 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| H9191_RS23050 (40515) | 40515..41204 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| H9191_RS23055 (41248) | 41248..41598 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| H9191_RS23060 (42130) | 42130..45945 | - | 3816 | WP_223364258.1 | hypothetical protein | - |
| H9191_RS23065 (46171) | 46171..46356 | + | 186 | Protein_40 | hypothetical protein | - |
| H9191_RS23070 (46374) | 46374..46721 | - | 348 | WP_000142450.1 | DUF6404 family protein | - |
| H9191_RS23075 (47023) | 47023..47505 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| H9191_RS23080 (47622) | 47622..48470 | - | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| H9191_RS23085 (48516) | 48516..48794 | - | 279 | WP_097309154.1 | type II toxin-antitoxin system toxin YacB | - |
| H9191_RS23095 (48904) | 48904..49620 | - | 717 | Protein_45 | Tn3 family transposase | - |
| H9191_RS23100 (49654) | 49654..52659 | - | 3006 | WP_001143760.1 | Tn3-like element Tn3 family transposase | - |
| H9191_RS23105 (52823) | 52823..53380 | + | 558 | WP_001235713.1 | recombinase family protein | - |
| H9191_RS23110 (53563) | 53563..54423 | + | 861 | WP_000027057.1 | broad-spectrum class A beta-lactamase TEM-1 | - |
| H9191_RS23115 (54571) | 54571..54918 | - | 348 | Protein_49 | IS6-like element IS26 family transposase | - |
| H9191_RS23120 (55165) | 55165..55638 | - | 474 | WP_004201280.1 | trimethoprim-resistant dihydrofolate reductase DfrA14 | - |
| H9191_RS23125 (55794) | 55794..56906 | + | 1113 | WP_024166810.1 | class 1 integron integrase IntI1 | - |
| H9191_RS23130 (56852) | 56852..57556 | - | 705 | WP_086525284.1 | IS6-like element IS26 family transposase | - |
| H9191_RS23135 (57623) | 57623..58239 | - | 617 | Protein_53 | transposase | - |
| H9191_RS23140 (58634) | 58634..59290 | + | 657 | WP_001516695.1 | quinolone resistance pentapeptide repeat protein QnrS1 | - |
| H9191_RS23145 (59609) | 59609..60037 | - | 429 | Protein_55 | recombinase family protein | - |
| H9191_RS23150 (60070) | 60070..61461 | - | 1392 | WP_001493761.1 | ISKra4-like element ISKpn19 family transposase | - |
| H9191_RS23155 (61498) | 61498..62070 | - | 573 | WP_001493762.1 | recombinase family protein | - |
| H9191_RS23160 (62207) | 62207..62752 | - | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| H9191_RS23165 (62915) | 62915..63157 | + | 243 | WP_000844627.1 | transposase | - |
| H9191_RS23170 (63189) | 63189..63839 | - | 651 | WP_159186494.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| H9191_RS23175 (63945) | 63945..65144 | + | 1200 | WP_032153701.1 | tetracycline efflux MFS transporter Tet(A) | - |
| H9191_RS23180 (65111) | 65111..65299 | - | 189 | Protein_62 | IS91 family transposase | - |
| H9191_RS23185 (65411) | 65411..65716 | - | 306 | WP_001255015.1 | LysR family transcriptional regulator | - |
| H9191_RS23190 (65744) | 65744..66958 | - | 1215 | WP_000214121.1 | chloramphenicol/florfenicol efflux MFS transporter FloR | - |
| H9191_RS23195 (67175) | 67175..68059 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| H9191_RS23200 (68090) | 68090..69583 | - | 1494 | WP_001120888.1 | IS91-like element ISVsa3 family transposase | - |
| H9191_RS23205 (69794) | 69794..70018 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| H9191_RS23210 (70015) | 70015..70752 | - | 738 | WP_001366550.1 | recombinase family protein | - |
| H9191_RS23215 (71238) | 71238..71378 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| H9191_RS23220 (71384) | 71384..72088 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H9191_RS23225 (72211) | 72211..72612 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H9191_RS23230 (72545) | 72545..72802 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H9191_RS23235 (72895) | 72895..73548 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| H9191_RS23240 (74487) | 74487..75344 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| H9191_RS23245 (75337) | 75337..75819 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| H9191_RS23250 (75812) | 75812..75859 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| H9191_RS23255 (75850) | 75850..76101 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| H9191_RS23260 (76118) | 76118..76375 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| H9191_RS23265 (76659) | 76659..76808 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (76852) | 76852..76913 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (76852) | 76852..76913 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (76852) | 76852..76913 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (76852) | 76852..76913 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| H9191_RS23270 (77169) | 77169..77243 | - | 75 | Protein_80 | endonuclease | - |
| H9191_RS23275 (77489) | 77489..77701 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| H9191_RS23280 (77837) | 77837..78397 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| H9191_RS23285 (78500) | 78500..79360 | - | 861 | WP_000704514.1 | alpha/beta hydrolase | - |
| H9191_RS23290 (79419) | 79419..80165 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| H9191_RS23295 (80185) | 80185..85455 | - | 5271 | WP_063074904.1 | conjugative transfer relaxase/helicase TraI | - |
| H9191_RS23300 (85537) | 85537..85764 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| H9191_RS23305 (85764) | 85764..86162 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H9191_RS23310 (86171) | 86171..88324 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| H9191_RS23315 (88577) | 88577..89308 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| H9191_RS23320 (89340) | 89340..89837 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| H9191_RS23325 (89853) | 89853..92675 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| H9191_RS23330 (92672) | 92672..94045 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| H9191_RS23335 (94045) | 94045..94425 | - | 381 | WP_241468324.1 | F-type conjugal transfer protein TrbF | - |
| H9191_RS23340 (94412) | 94412..94753 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| H9191_RS23345 (94683) | 94683..95228 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H9191_RS23350 (95215) | 95215..95499 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H9191_RS23355 (95580) | 95580..95894 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| H9191_RS23360 (95896) | 95896..96243 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| H9191_RS23365 (96259) | 96259..97002 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H9191_RS23370 (96995) | 96995..97252 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| H9191_RS23375 (97279) | 97279..99087 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H9191_RS23380 (99084) | 99084..99722 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H9191_RS23385 (99731) | 99731..100723 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| H9191_RS23390 (100720) | 100720..101352 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| H9191_RS23395 (101349) | 101349..101735 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| H9191_RS23400 (101732) | 101732..104359 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H9191_RS23405 (104519) | 104519..104740 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H9191_RS23410 (104875) | 104875..105390 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H9191_RS23415 (105387) | 105387..105638 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H9191_RS23420 (105650) | 105650..105847 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| H9191_RS23425 (105834) | 105834..106424 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| H9191_RS23430 (106414) | 106414..107841 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| H9191_RS23435 (107841) | 107841..108569 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| H9191_RS23440 (108556) | 108556..109122 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| H9191_RS23445 (109144) | 109144..109455 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H9191_RS23450 (109470) | 109470..109835 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| H9191_RS23455 (109868) | 109868..110269 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| H9191_RS23460 (110362) | 110362..111051 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| H9191_RS23465 (111238) | 111238..111621 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| H9191_RS23470 (111942) | 111942..112544 | + | 603 | WP_000243712.1 | transglycosylase SLT domain-containing protein | - |
| H9191_RS23475 (112841) | 112841..113662 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| H9191_RS23480 (113780) | 113780..114067 | - | 288 | WP_063121090.1 | hypothetical protein | - |
| H9191_RS23485 (114092) | 114092..114298 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| H9191_RS23490 (114368) | 114368..114540 | + | 173 | Protein_124 | hypothetical protein | - |
| H9191_RS23495 (114538) | 114538..114768 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| H9191_RS23500 (114988) | 114988..115113 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H9191_RS23505 (115055) | 115055..115204 | - | 150 | Protein_127 | plasmid maintenance protein Mok | - |
| - (115190) | 115190..115414 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (115190) | 115190..115414 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (115190) | 115190..115414 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (115190) | 115190..115414 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| H9191_RS23510 (115226) | 115226..115414 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| H9191_RS23515 (115383) | 115383..116145 | - | 763 | Protein_129 | plasmid SOS inhibition protein A | - |
| H9191_RS23520 (116142) | 116142..116576 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| H9191_RS23525 (116631) | 116631..116828 | - | 198 | Protein_131 | hypothetical protein | - |
| H9191_RS23530 (116856) | 116856..117089 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| H9191_RS23535 (117157) | 117157..117696 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| H9191_RS23540 (117722) | 117722..117928 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| H9191_RS23545 (117998) | 117998..118078 | + | 81 | Protein_135 | hypothetical protein | - |
| H9191_RS23550 (118261) | 118261..118430 | - | 170 | Protein_136 | hypothetical protein | - |
| H9191_RS23555 (119024) | 119024..119995 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H9191_RS23560 (119995) | 119995..121161 | - | 1167 | WP_001238646.1 | plasmid-partitioning protein SopA | - |
| H9191_RS23570 (122643) | 122643..124844 | - | 2202 | WP_000973520.1 | ferric aerobactin receptor IutA | - |
| H9191_RS23575 (124870) | 124870..126203 | - | 1334 | Protein_141 | NADPH-dependent L-lysine N(6)-monooxygenase IucD | - |
| H9191_RS23580 (126200) | 126200..127942 | - | 1743 | WP_001015721.1 | NIS family aerobactin synthetase IucC | - |
| H9191_RS23585 (127942) | 127942..128889 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase IucB | - |
| H9191_RS23590 (128890) | 128890..130614 | - | 1725 | WP_000602863.1 | NIS family aerobactin synthetase IucA | - |
| H9191_RS23595 (130750) | 130750..131943 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| H9191_RS23600 (132323) | 132323..132703 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| H9191_RS23605 (133044) | 133044..133457 | - | 414 | Protein_147 | phosphopyruvate hydratase | - |
| H9191_RS23610 (133455) | 133455..133712 | + | 258 | Protein_148 | Tn3 family transposase | - |
| H9191_RS23615 (133946) | 133946..134803 | - | 858 | WP_000968139.1 | iron/manganese ABC transporter permease subunit SitD | - |
| H9191_RS23620 (134800) | 134800..135657 | - | 858 | WP_001101723.1 | iron/manganese ABC transporter permease subunit SitC | - |
| H9191_RS23625 (135654) | 135654..136481 | - | 828 | WP_000983710.1 | iron/manganese ABC transporter ATP-binding protein SitB | - |
| H9191_RS23630 (136481) | 136481..137395 | - | 915 | WP_000949004.1 | iron/manganese ABC transporter substrate-binding protein SitA | - |
| H9191_RS23635 (137751) | 137751..138448 | + | 698 | WP_223155668.1 | IS1-like element IS1A family transposase | - |
| H9191_RS23640 (138628) | 138628..139141 | - | 514 | Protein_154 | DUF4113 domain-containing protein | - |
| H9191_RS23645 (139202) | 139202..139306 | - | 105 | Protein_155 | AAA family ATPase | - |
| H9191_RS23650 (139308) | 139308..139631 | - | 324 | Protein_156 | helix-turn-helix domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|