MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 178411 bp
Accession: NZ_CP058546        Location: 1..178411         Organism: Klebsiella pneumoniae strain S161-2       Replicon: plasmid pS161-2.2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYH18_RS26765 884..1846 + 963 Protein_1 kinase -
HYH18_RS26770 2225..2706 + 482 Protein_2 hypothetical protein -
HYH18_RS26775 2982..3386 - 405 WP_071444019.1 DUF2251 domain-containing protein -
HYH18_RS26780 4067..4345 - 279 WP_049007085.1 DUF1778 domain-containing protein -
HYH18_RS26785 4439..4651 - 213 WP_071444020.1 hypothetical protein -
HYH18_RS28495 5300..5446 - 147 Protein_6 DUF2235 domain-containing protein -
HYH18_RS26795 5481..5591 + 111 Protein_7 glutathione ABC transporter permease GsiC -
HYH18_RS26800 5675..7345 - 1671 WP_071444021.1 AMP-binding protein -
HYH18_RS26805 7326..8591 - 1266 WP_071444022.1 MSMEG_0569 family flavin-dependent oxidoreductase -
HYH18_RS26810 8609..8899 - 291 WP_011154627.1 MSMEG_0570 family nitrogen starvation response protein -
HYH18_RS26815 8911..9873 - 963 WP_004210297.1 sll0787 family AIR synthase-like protein -
HYH18_RS26820 9870..10433 - 564 WP_004210298.1 GNAT family N-acetyltransferase -
HYH18_RS26825 10444..11553 - 1110 WP_004210300.1 MSMEG_0568 family radical SAM protein -
HYH18_RS26830 11513..12514 - 1002 WP_004902273.1 Nit6803 family nitriliase -
HYH18_RS26835 12528..13010 - 483 WP_004210304.1 MSMEG_0572 family nitrogen starvation response protein -
HYH18_RS26840 13377..14777 + 1401 WP_004210305.1 PLP-dependent aminotransferase family protein -
HYH18_RS26845 15360..16805 - 1446 WP_224715715.1 Methyl-accepting chemotaxis protein McpQ VF
HYH18_RS26850 16782..17486 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
HYH18_RS26855 17676..18491 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
HYH18_RS26860 18642..19345 + 704 Protein_20 IS6 family transposase IS15DII Transposase
HYH18_RS26865 19467..20372 + 906 WP_000219391.1 hypothetical protein ARG
HYH18_RS26870 20369..21607 + 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
HYH18_RS26875 21607..22191 + 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
HYH18_RS26880 22684..23448 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
HYH18_RS26885 23566..23631 - 66 Protein_25 EAL domain-containing protein -
HYH18_RS26890 23675..23980 - 306 WP_000130000.1 hypothetical protein Relaxase
HYH18_RS26895 23991..25196 - 1206 WP_000184001.1 chromate efflux transporter -
HYH18_RS26900 25352..25555 - 204 WP_000376616.1 hypothetical protein -
HYH18_RS26905 25683..26522 - 840 WP_000259031.1 Dihydropteroate synthase ARG
HYH18_RS26910 26516..26851 - 336 WP_052238321.1 SMR family transporter -
HYH18_RS26915 26744..27109 + 366 WP_025999322.1 hydrogenase maturation nickel metallochaperone HypA -
HYH18_RS26920 27113..27988 - 876 WP_004193231.1 LysR family transcriptional regulator AmpR -
HYH18_RS26925 28099..29238 + 1140 WP_004236386.1 Beta-lactamase ARG
HYH18_RS26930 29433..30254 + 822 WP_013214003.1 hypothetical protein -
HYH18_RS26935 30212..30400 + 189 Protein_35 LacI family transcriptional regulator -
HYH18_RS26940 30589..30819 - 231 WP_004193241.1 phage shock protein PspD -
HYH18_RS26945 30828..31187 - 360 WP_004193243.1 envelope stress response membrane protein PspC -
HYH18_RS26950 31187..31411 - 225 WP_004193245.1 envelope stress response membrane protein PspB -
HYH18_RS26955 31466..32134 - 669 WP_003020532.1 phage shock protein PspA -
HYH18_RS26960 32290..33279 + 990 WP_017900991.1 Psp operon transcriptional activator VF
HYH18_RS26965 33362..34006 + 645 WP_017900990.1 Pentapeptide repeat protein ARG
HYH18_RS26970 34102..35010 - 909 WP_004193260.1 putative oxidoreductase YghA VF
HYH18_RS26975 35187..35702 - 516 WP_017900989.1 2-oxo-tetronate isomerase -
HYH18_RS26980 35713..36159 - 447 WP_004193264.1 DUF421 domain-containing protein -
HYH18_RS26985 36169..36672 - 504 WP_004193267.1 hypothetical protein -
HYH18_RS26990 36804..37196 + 393 WP_004193269.1 YdeI family stress tolerance OB fold protein -
HYH18_RS26995 37497..39140 + 1644 WP_004193272.1 ABC transporter substrate-binding protein SapA -
HYH18_RS27000 39137..40102 + 966 WP_004193276.1 peptide ABC transporter permease SapB -
HYH18_RS27005 40089..40547 + 459 Protein_49 peptide ABC transporter permease -
HYH18_RS27010 40778..42319 - 1542 WP_000050481.1 IS91 family transposase ISVsa3 Transposase
HYH18_RS27015 42724..43561 - 838 Protein_51 Dihydropteroate synthase ARG
HYH18_RS27020 43555..43902 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
HYH18_RS27025 44125..44577 - 453 WP_001749986.1 hypothetical protein ARG
HYH18_RS27030 44662..45294 - 633 WP_000186237.1 Chloramphenicol acetyltransferase VF
HYH18_RS27035 45432..46262 - 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
HYH18_RS27040 46393..46947 - 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
HYH18_RS27045 47239..48245 + 1007 Protein_57 IS91 family transposase ISAzo26 Transposase
HYH18_RS27050 48448..48798 + 351 WP_000454193.1 DUF3330 domain-containing protein -
HYH18_RS27055 48974..49533 + 560 Protein_59 Tn3 family transposase TnpR_TnAs1 Transposase
HYH18_RS27060 49537..52503 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
HYH18_RS27065 52757..53071 + 315 WP_004186895.1 hypothetical protein -
HYH18_RS27070 53314..53796 - 483 WP_004210306.1 hypothetical protein -
HYH18_RS27075 55012..55896 + 885 WP_004210308.1 RepB family plasmid replication initiator protein -
HYH18_RS27080 56206..56355 + 150 WP_175459186.1 hypothetical protein -
HYH18_RS27085 56416..56943 + 528 WP_237085342.1 hypothetical protein -
HYH18_RS27090 57004..57666 + 663 WP_237085343.1 hypothetical protein -
HYH18_RS27095 57885..58718 - 834 WP_004902281.1 hypothetical protein -
HYH18_RS27100 58981..59949 + 969 WP_078207718.1 IS5 family transposase IS903B Transposase
HYH18_RS27105 60104..60358 - 255 WP_004213836.1 Hha/YmoA family nucleoid-associated regulatory protein -
HYH18_RS27110 60536..61672 + 1137 WP_004213833.1 tyrosine-type recombinase/integrase -
HYH18_RS27115 61738..62055 - 318 WP_004213829.1 hypothetical protein -
HYH18_RS27120 62207..62530 - 324 WP_004197568.1 hypothetical protein -
HYH18_RS27125 62815..63285 - 471 WP_004902291.1 hypothetical protein -
HYH18_RS27130 63282..64241 - 960 WP_011154511.1 DNA replication terminus site-binding protein -
HYH18_RS27135 64284..64691 - 408 WP_004186937.1 hypothetical protein -
HYH18_RS27140 64701..65144 - 444 WP_194433537.1 hypothetical protein -
HYH18_RS27145 65165..66240 - 1076 Protein_77 IS3 family transposase ISEc27 Transposase
HYH18_RS27150 66408..67376 + 969 WP_004213807.1 IS110 family transposase ISSm3 Transposase
HYH18_RS27155 67395..67559 - 165 Protein_79 IS3 family transposase IS2 Transposase
HYH18_RS27160 67645..69237 - 1593 WP_004902302.1 IS66 family transposase ISKox1 Transposase
HYH18_RS27165 69268..69618 - 351 WP_004189161.1 IS66 family transposase ISKox1 Transposase
HYH18_RS27170 69615..70055 - 441 WP_004215130.1 IS66 family transposase ISKox1 Transposase
HYH18_RS27175 70140..70434 + 295 Protein_83 DUF4113 domain-containing protein -
HYH18_RS27180 70513..70741 + 229 Protein_84 type II toxin-antitoxin system Phd/YefM family antitoxin -
HYH18_RS27185 71640..72611 - 972 WP_004117790.1 ParB/RepB/Spo0J family plasmid partition protein -
HYH18_RS27190 72611..73777 - 1167 WP_004211841.1 Sporulation initiation inhibitor protein Soj VF
HYH18_RS27195 74507..75517 + 1011 WP_004211839.1 RepB family plasmid replication initiator protein -
HYH18_RS27200 76339..77079 - 741 Protein_88 site-specific integrase -
HYH18_RS27205 77427..77700 + 274 Protein_89 IS3 family transposase -
HYH18_RS27210 77837..78373 - 537 WP_004211835.1 hypothetical protein -
HYH18_RS27215 79429..79430 - 2 WP_223271235.1 IS3 family transposase ISYpe1 Transposase
HYH18_RS27220 80105..81127 + 1023 Protein_92 IS21 family transposase ISSen8 Transposase
HYH18_RS27225 81124..81906 + 783 WP_071443911.1 IS21 family transposase ISSen8 Transposase
HYH18_RS27230 81972..82621 - 650 Protein_94 IS3 family transposase ISSen4 Transposase
HYH18_RS27235 82690..83217 - 528 WP_071443912.1 RES domain-containing protein -
HYH18_RS28500 83177..83299 - 123 WP_226323909.1 RES domain-containing protein -
HYH18_RS27240 83260..83760 - 501 WP_004214674.1 hypothetical protein -
HYH18_RS27245 83933..84256 - 324 WP_004902338.1 hypothetical protein -
HYH18_RS27250 84253..84690 - 438 WP_004902343.1 hypothetical protein -
HYH18_RS27255 84690..85721 - 1032 WP_004902347.1 ParB/RepB/Spo0J family partition protein -
HYH18_RS27260 85721..86587 - 867 WP_011251296.1 AAA family ATPase -
HYH18_RS27265 87111..87362 - 252 WP_004902354.1 hypothetical protein -
HYH18_RS27270 87551..88840 + 1290 WP_225733970.1 hypothetical protein -
HYH18_RS27275 88948..89298 + 351 WP_226324429.1 hypothetical protein -
HYH18_RS27280 89277..89444 - 168 Protein_105 IS1 family transposase -
HYH18_RS27285 89748..90677 + 930 WP_004213558.1 Recombination-promoting nuclease RpnA VF
HYH18_RS27290 90822..91601 - 780 WP_004213560.1 site-specific integrase -
HYH18_RS27295 91598..92419 - 822 WP_004213562.1 hypothetical protein -
HYH18_RS27300 92474..92773 - 300 WP_052433691.1 hypothetical protein -
HYH18_RS27305 93354..94328 - 975 WP_004213565.1 sensor domain-containing diguanylate cyclase -
HYH18_RS27310 94965..95873 + 909 WP_001372261.1 HNH endonuclease -
HYH18_RS27315 96261..96611 - 351 WP_004213569.1 DUF305 domain-containing protein -
HYH18_RS27320 96755..97186 - 432 WP_023302802.1 silver-binding protein SilE -
HYH18_RS27325 97437..98912 - 1476 WP_016947610.1 copper/silver sensor histidine kinase SilS -
HYH18_RS27330 98905..99585 - 681 WP_004213574.1 Transcriptional regulatory protein CusR VF
HYH18_RS27335 99775..101160 + 1386 WP_004213577.1 Cation efflux system protein CusC VF
HYH18_RS27340 101189..101542 + 354 WP_001246152.1 Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone SilF -
HYH18_RS27345 101656..102948 + 1293 WP_004098959.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
HYH18_RS27350 102959..106105 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
HYH18_RS27355 106192..106632 + 441 WP_000758228.1 DUF411 domain-containing protein -
HYH18_RS27360 106759..109200 + 2442 WP_194433528.1 Ag(+)-translocating P-type ATPase SilP -
HYH18_RS27365 109241..109438 + 198 WP_000843497.1 DUF2933 domain-containing protein -
HYH18_RS27370 109472..110209 - 738 WP_000287501.1 Murein DD-endopeptidase MepM VF
HYH18_RS27375 110498..110947 - 450 WP_025999288.1 copper resistance protein -
HYH18_RS27380 111182..112999 + 1818 WP_237085340.1 multicopper oxidase PcoA -
HYH18_RS27385 113005..113895 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
HYH18_RS27390 113935..114315 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
HYH18_RS27395 114320..115249 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
HYH18_RS27400 115304..115984 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
HYH18_RS27405 115981..117381 + 1401 WP_002436614.1 copper resistance membrane spanning protein PcoS -
HYH18_RS27410 117597..118031 + 435 WP_004118347.1 hypothetical protein -
HYH18_RS27415 118211..118373 - 163 Protein_132 type II toxin-antitoxin system RelE/ParE family toxin -
HYH18_RS27420 118410..118508 - 99 WP_004118688.1 type II toxin-antitoxin system RelE/ParE family toxin -
HYH18_RS27425 118656..119647 + 992 Protein_134 IS3 family transposase ISEcl1 Transposase
HYH18_RS27430 119679..120647 + 969 WP_194433525.1 IS5 family transposase IS903B Transposase
HYH18_RS27435 120705..121754 - 1050 Protein_136 IS66 family transposase ISKpn24 Transposase
HYH18_RS27440 121803..122150 - 348 WP_004114612.1 IS66 family transposase ISCfr14 Transposase
HYH18_RS27445 122147..122485 - 339 WP_023288266.1 IS66 family transposase ISSgsp1 Transposase
HYH18_RS27450 122599..123036 + 438 Protein_139 IS3 family transposase ISEc27 Transposase
HYH18_RS27455 123241..123552 + 312 WP_011251285.1 type II toxin-antitoxin system HigB family toxin Toxin Detail
HYH18_RS27460 123549..123968 + 420 WP_011251286.1 helix-turn-helix domain-containing protein Antitoxin Detail
HYH18_RS27465 124115..125083 + 969 WP_194433524.1 IS5 family transposase IS903 Transposase
HYH18_RS27470 125337..126125 - 789 WP_114263119.1 hypothetical protein -
HYH18_RS27475 126125..126421 - 297 WP_227662480.1 conjugative transfer protein MobI(A/C) -
HYH18_RS27480 127182..127817 + 636 WP_227662472.1 hypothetical protein -
HYH18_RS27485 128130..128654 + 525 WP_071444207.1 hypothetical protein -
HYH18_RS27490 128852..129550 + 699 Protein_147 IS1 family transposase IS1X3 Transposase
HYH18_RS27495 129574..130377 - 804 WP_101979506.1 hypothetical protein -
HYH18_RS27500 130438..131784 - 1347 Protein_149 ISNCY family transposase ISLad2 Transposase
HYH18_RS27505 132023..132382 + 360 Protein_150 LysR substrate-binding domain-containing protein -
HYH18_RS27510 132544..133980 - 1437 WP_050582443.1 PLP-dependent aminotransferase family protein -
HYH18_RS27515 134079..134867 + 789 WP_071444140.1 arylamine N-acetyltransferase -
HYH18_RS27520 135209..135794 + 586 Protein_153 IS110 family transposase IS1618 Transposase
HYH18_RS27525 136194..136427 + 234 Protein_154 Tn3 family transposase TnpA_Tn3 Transposase
HYH18_RS27530 136605..138138 + 1534 Protein_155 IS3 family transposase ISKpn38 Transposase
HYH18_RS27535 138336..138980 + 645 WP_016240411.1 pentapeptide repeat-containing protein -
HYH18_RS27540 139217..140263 - 1047 WP_000627691.1 DUF3800 domain-containing protein -
HYH18_RS27545 140315..141721 - 1407 WP_016240413.1 ISNCY family transposase ISKpn21 Transposase
HYH18_RS27550 141906..142395 - 490 Protein_159 IS3 family transposase ISEhe3 Transposase
HYH18_RS27555 142397..142879 + 483 Protein_160 hypothetical protein -
HYH18_RS27560 142897..143865 + 969 WP_194433531.1 IS5 family transposase IS903B Transposase
HYH18_RS27565 143922..144107 + 186 Protein_162 transposase -
HYH18_RS27570 144379..144867 - 489 WP_032469931.1 hypothetical protein -
HYH18_RS27575 144864..149540 - 4677 WP_071444142.1 RecQ family ATP-dependent DNA helicase -
HYH18_RS27580 149537..150466 - 930 WP_045896958.1 DNA-processing protein DprA -
HYH18_RS27585 150621..150929 - 309 Protein_166 IS3 family transposase ISLad1 Transposase
HYH18_RS27590 150946..151980 - 1035 WP_228302852.1 IS110 family transposase ISEc21 Transposase
HYH18_RS27595 151949..152917 - 969 WP_077270417.1 IS5 family transposase IS903 Transposase
HYH18_RS27600 153009..153236 + 228 WP_237085344.1 NAD(P)H-dependent oxidoreductase -
HYH18_RS27605 153252..153386 + 135 Protein_170 carboxymuconolactone decarboxylase family protein -
HYH18_RS27610 153456..154454 + 999 WP_237085341.1 IS5 family transposase ISKpn26 Transposase
HYH18_RS27615 154561..156186 - 1626 Protein_172 HsdR family type I site-specific deoxyribonuclease -
HYH18_RS27620 156303..157571 - 1269 WP_071444116.1 restriction endonuclease subunit S -
HYH18_RS27625 157568..159124 - 1557 WP_071444117.1 type I restriction-modification system subunit M -
HYH18_RS27630 159327..161192 - 1866 WP_071444119.1 DUF262 domain-containing protein -
HYH18_RS27640 163241..163510 - 270 WP_125450405.1 hypothetical protein -
HYH18_RS27645 163555..163761 - 207 Protein_178 IS3 family transposase IS2 Transposase
HYH18_RS27655 165684..166112 - 429 WP_040150689.1 glutaredoxin-dependent arsenate reductase -
HYH18_RS27660 166125..167414 - 1290 WP_040150692.1 arsenic transporter -
HYH18_RS27665 167459..167779 - 321 WP_040150694.1 transcriptional regulator -
HYH18_RS27670 167865..168563 + 699 WP_040150695.1 arsenical resistance protein ArsH -
HYH18_RS27675 168572..169486 - 915 Protein_184 IS3 family transposase ISKpn8 Transposase
HYH18_RS27680 169494..170462 + 969 WP_077254853.1 IS5 family transposase IS903B Transposase
HYH18_RS27685 170632..171003 - 372 WP_194433529.1 IS3 family transposase ISKpn8 Transposase
HYH18_RS27690 171698..171958 + 261 WP_004026352.1 hypothetical protein -
HYH18_RS27695 172068..172538 - 471 WP_004026354.1 RES family NAD+ phosphorylase Toxin Detail
HYH18_RS27700 172535..172978 - 444 WP_004181895.1 DUF2384 domain-containing protein Antitoxin Detail
HYH18_RS27705 173079..173756 - 678 Protein_190 DUF4113 domain-containing protein -
HYH18_RS27710 173825..174607 - 783 WP_032437422.1 IS21 family transposase ISSen3 Transposase
HYH18_RS27715 174604..175626 - 1023 WP_129304158.1 IS21 family transposase ISSen3 Transposase
HYH18_RS27720 175714..176039 + 326 Protein_193 IS5 family transposase IS903 Transposase
HYH18_RS27725 176096..176296 - 201 Protein_194 IS3 family transposase ISYps8 Transposase
HYH18_RS27730 176756..177440 - 685 Protein_195 IS1 family transposase -
HYH18_RS27735 177519..177698 + 180 WP_007372130.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance