MGE detailed information
MGE type: Conjugative plasmid MGE length: 140410 bp
Accession: NZ_CP058343 Location: 1..140410 Organism: Escherichia coli strain W60 Replicon: plasmid pECW601
Accession: NZ_CP058343 Location: 1..140410 Organism: Escherichia coli strain W60 Replicon: plasmid pECW601
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HXP40_RS22815 () | 330..1284 | - | 955 | Protein_0 | hypothetical protein | VF |
| HXP40_RS22820 () | 2557..2715 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| HXP40_RS22825 () | 2899..3638 | + | 740 | Protein_2 | IS3 family transposase IS629 | Transposase |
| HXP40_RS22830 () | 4311..5819 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| HXP40_RS22835 () | 5909..6382 | + | 474 | Protein_4 | IS3 family transposase IS629 | Transposase |
| HXP40_RS22840 () | 6530..6798 | - | 269 | Protein_5 | IS3 family transposase ISLad1 | Transposase |
| HXP40_RS22845 () | 6855..7552 | + | 698 | Protein_6 | IS1 family transposase | - |
| HXP40_RS22850 () | 7630..9019 | - | 1390 | Protein_7 | ISNCY family transposase ISKpn21 | Transposase |
| HXP40_RS22855 () | 9329..9478 | - | 150 | Protein_8 | IS3 family transposase IS2 | Transposase |
| HXP40_RS22860 () | 9656..10849 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| HXP40_RS22865 () | 12072..13308 | - | 1237 | Protein_10 | IS3 family transposase IS2 | Transposase |
| HXP40_RS22870 () | 13935..14228 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| HXP40_RS22875 () | 14286..14485 | - | 200 | Protein_12 | lysis protein | - |
| HXP40_RS22880 () | 15039..16141 | + | 1103 | Protein_13 | IS481 family transposase ISKpn28 | Transposase |
| HXP40_RS22885 () | 17377..18492 | + | 1116 | WP_001318220.1 | hypothetical protein | VF |
| HXP40_RS22890 () | 18632..22291 | + | 3660 | WP_001111199.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| HXP40_RS22895 () | 22395..23624 | + | 1230 | WP_000933675.1 | hypothetical protein | VF |
| HXP40_RS22900 () | 23709..24665 | + | 957 | WP_064055648.1 | hypothetical protein | VF |
| HXP40_RS22905 () | 24710..26887 | - | 2178 | WP_001222186.1 | Vitamin B12 transporter BtuB | VF |
| HXP40_RS22910 () | 27122..27819 | + | 698 | Protein_19 | IS1 family transposase | - |
| HXP40_RS22915 () | 28050..29162 | + | 1113 | WP_001300563.1 | IS4 family transposase IS421 | Transposase |
| HXP40_RS22920 () | 29708..29989 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| HXP40_RS22925 () | 30162..30329 | + | 168 | Protein_22 | colicin-B | - |
| HXP40_RS22930 () | 30347..30874 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| HXP40_RS22935 () | 31118..31933 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| HXP40_RS22940 () | 31983..32336 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| HXP40_RS22945 () | 32514..33305 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| HXP40_RS22950 () | 33302..33991 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| HXP40_RS22955 () | 34035..34385 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| HXP40_RS22960 () | 34917..38738 | - | 3822 | WP_064055658.1 | hypothetical protein | - |
| HXP40_RS22965 () | 38982..39143 | + | 162 | WP_000251882.1 | hypothetical protein | - |
| HXP40_RS22970 () | 39161..39508 | - | 348 | WP_000142450.1 | hypothetical protein | - |
| HXP40_RS22975 () | 39810..40292 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| HXP40_RS22980 () | 40409..41257 | - | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| HXP40_RS22985 () | 41303..41584 | - | 282 | WP_112923716.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HXP40_RS22990 () | 41581..41658 | - | 78 | Protein_35 | toxin-antitoxin system protein | - |
| HXP40_RS22995 () | 41691..43442 | - | 1752 | Protein_36 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HXP40_RS23000 () | 43431..43838 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| HXP40_RS23005 () | 43976..44860 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| HXP40_RS23010 () | 44892..46091 | - | 1200 | WP_000804064.1 | Multidrug resistance protein MdtG | ARG |
| HXP40_RS23015 () | 46197..46847 | + | 651 | WP_038989485.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HXP40_RS23020 () | 46879..47124 | - | 246 | WP_041937891.1 | hypothetical protein | - |
| HXP40_RS23025 () | 47104..47475 | - | 372 | Protein_42 | DUF4158 domain-containing protein | - |
| HXP40_RS23030 () | 47479..48039 | - | 561 | WP_001161490.1 | recombinase family protein | - |
| HXP40_RS23035 () | 48215..48565 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HXP40_RS23040 () | 48768..49781 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| HXP40_RS23045 () | 49926..50423 | + | 498 | WP_001083725.1 | hypothetical protein | ARG |
| HXP40_RS23050 () | 50535..50825 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HXP40_RS23055 () | 50831..51622 | + | 792 | WP_001206356.1 | hypothetical protein | ARG |
| HXP40_RS23060 () | 51786..52133 | + | 348 | WP_000679427.1 | Spermidine export protein MdtJ | ARG |
| HXP40_RS23065 () | 52127..52966 | + | 840 | WP_000259031.1 | hypothetical protein | ARG |
| HXP40_RS23070 () | 53371..54912 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| HXP40_RS23075 () | 55225..56256 | + | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| HXP40_RS23080 () | 56267..56905 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| HXP40_RS23085 () | 56910..57275 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| HXP40_RS23090 () | 57279..58091 | - | 813 | WP_023408309.1 | hypothetical protein | ARG |
| HXP40_RS23095 () | 58192..58485 | - | 294 | Protein_56 | IS30 family transposase ISAba125 | Transposase |
| HXP40_RS23100 () | 58650..59354 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HXP40_RS23105 () | 59950..61722 | - | 1773 | WP_001262766.1 | DUF262 domain-containing protein | - |
| HXP40_RS23110 () | 62007..62408 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HXP40_RS23115 () | 62341..62598 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HXP40_RS23120 () | 62691..63344 | - | 654 | WP_000616800.1 | CPBP family intramembrane metalloprotease | - |
| HXP40_RS23125 () | 64283..65140 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| HXP40_RS23130 () | 65133..65615 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| HXP40_RS23135 () | 65608..65682 | - | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| HXP40_RS23140 () | 65914..66171 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| HXP40_RS23145 () | 66455..66661 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 66648..66709 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 66648..66709 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 66648..66709 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 66648..66709 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| HXP40_RS23150 () | 66965..67039 | - | 75 | Protein_67 | endonuclease | - |
| HXP40_RS23155 () | 67285..67497 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| HXP40_RS23160 () | 67633..68193 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| HXP40_RS23165 () | 68296..69156 | - | 861 | WP_000704514.1 | hypothetical protein | VF |
| HXP40_RS23170 () | 69215..69961 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| HXP40_RS23175 () | 69981..75251 | - | 5271 | WP_000986962.1 | ATP-dependent RecD-like DNA helicase | Relaxase |
| HXP40_RS23180 () | 75333..75560 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| HXP40_RS23185 () | 75560..75958 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| HXP40_RS23190 () | 75967..78120 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| HXP40_RS23195 () | 78373..79104 | - | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| HXP40_RS23200 () | 79136..79633 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| HXP40_RS23205 () | 79649..82471 | - | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HXP40_RS23210 () | 82468..83841 | - | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| HXP40_RS23215 () | 83841..84254 | - | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| HXP40_RS23220 () | 84208..84549 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| HXP40_RS23225 () | 84479..85024 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HXP40_RS23230 () | 85011..85295 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HXP40_RS23235 () | 85376..85690 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| HXP40_RS23240 () | 85692..86039 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| HXP40_RS23245 () | 86055..86798 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HXP40_RS23250 () | 86791..87048 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| HXP40_RS23255 () | 87075..88883 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HXP40_RS23260 () | 88880..89518 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HXP40_RS23265 () | 89527..90519 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| HXP40_RS23270 () | 90516..91148 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| HXP40_RS23275 () | 91145..91531 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| HXP40_RS23280 () | 91528..94155 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| HXP40_RS23285 () | 94315..94536 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| HXP40_RS23290 () | 94671..95186 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HXP40_RS23295 () | 95183..95434 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| HXP40_RS23300 () | 95446..95676 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| HXP40_RS23305 () | 95630..96220 | - | 591 | WP_001376242.1 | conjugal transfer protein TraP | - |
| HXP40_RS23310 () | 96210..97637 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| HXP40_RS23315 () | 97637..98341 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| HXP40_RS23320 () | 98352..98918 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| HXP40_RS23325 () | 98940..99251 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HXP40_RS23330 () | 99266..99631 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| HXP40_RS23335 () | 99664..100059 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| HXP40_RS23340 () | 100158..100847 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| HXP40_RS23345 () | 101034..101417 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| HXP40_RS23350 () | 101738..102340 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| HXP40_RS23355 () | 102637..103458 | - | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| HXP40_RS23360 () | 103576..103863 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HXP40_RS23365 () | 104784..104942 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 104986..105210 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 104986..105210 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 104986..105210 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 104986..105210 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| HXP40_RS23370 () | 105022..105210 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| HXP40_RS23375 () | 105222..105941 | - | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| HXP40_RS23380 () | 105938..106372 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| HXP40_RS23385 () | 106427..106624 | - | 198 | Protein_114 | hypothetical protein | - |
| HXP40_RS23390 () | 106652..106885 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| HXP40_RS23395 () | 106953..107450 | - | 498 | WP_042039995.1 | single-stranded DNA-binding protein | - |
| HXP40_RS23400 () | 107600..109501 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| HXP40_RS23405 () | 110358..111899 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| HXP40_RS23410 () | 111914..112660 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| HXP40_RS23415 () | 112846..113052 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| HXP40_RS23420 () | 114191..115162 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HXP40_RS23425 () | 115162..116328 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| HXP40_RS23430 () | 116628..117325 | - | 698 | Protein_123 | IS1-like element IS1A family transposase | - |
| HXP40_RS23435 () | 117810..120011 | - | 2202 | WP_000973520.1 | Vitamin B12 transporter BtuB | VF |
| HXP40_RS23440 () | 120093..121370 | - | 1278 | WP_000750130.1 | Ferredoxin--NADP reductase | VF |
| HXP40_RS23445 () | 121367..123109 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| HXP40_RS23450 () | 123109..124056 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| HXP40_RS23455 () | 124057..125781 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| HXP40_RS23460 () | 125917..127110 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| HXP40_RS23465 () | 127490..127870 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| HXP40_RS23470 () | 128211..128624 | - | 414 | Protein_131 | phosphopyruvate hydratase | - |
| HXP40_RS23475 () | 128622..128879 | + | 258 | Protein_132 | Tn3 family transposase | - |
| HXP40_RS23480 () | 129113..129970 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| HXP40_RS23485 () | 129967..130824 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| HXP40_RS23490 () | 130821..131648 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| HXP40_RS23495 () | 131648..132562 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| HXP40_RS23500 () | 132918..133615 | + | 698 | Protein_137 | IS1-like element IS1A family transposase | - |
| HXP40_RS23505 () | 133795..134308 | - | 514 | Protein_138 | DUF4113 domain-containing protein | - |
| HXP40_RS23510 () | 134369..134473 | - | 105 | Protein_139 | AAA family ATPase | - |
| HXP40_RS23515 () | 134475..134798 | - | 324 | Protein_140 | IS21 family transposase IS21 | Transposase |
| HXP40_RS23520 () | 135544..136521 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| HXP40_RS23525 () | 136806..137546 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| HXP40_RS23530 () | 137667..137855 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| HXP40_RS23535 () | 138229..139131 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| HXP40_RS23540 () | 139200..140307 | - | 1108 | Protein_145 | SDR family oxidoreductase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|