NZ_CP0568841..198658

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 198658 bp
Accession: NZ_CP056884        Location: 1..198658         Organism: Klebsiella pneumoniae strain RHBSTW-00062       Replicon: plasmid pRHBSTW-00062_2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV049_RS25645 () 1..1011 + 1011 WP_000200070.1 RepB family plasmid replication initiator protein -
HV049_RS25650 () 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
HV049_RS25655 () 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
HV049_RS25660 () 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
HV049_RS25665 () 4917..5885 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
HV049_RS25670 () 6558..6815 - 258 WP_004197688.1 hypothetical protein -
HV049_RS25675 () 7435..8871 + 1437 WP_080895248.1 putative cyclic di-GMP phosphodiesterase PdeB VF
HV049_RS25680 () 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
HV049_RS25685 () 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
HV049_RS25690 () 13343..14040 - 698 Protein_9 IS1 family transposase IS1X2 Transposase
HV049_RS25700 () 15529..16013 + 485 Protein_11 IS1 family transposase IS1X2 Transposase
HV049_RS25705 () 16029..16571 + 543 Protein_12 ISL3 family transposase ISKpn25 Transposase
HV049_RS25710 () 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
HV049_RS25715 () 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
HV049_RS25720 () 19017..19697 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
HV049_RS25725 () 19887..21272 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
HV049_RS25730 () 21301..21654 + 354 WP_001246153.1 cation efflux system protein CusF -
HV049_RS25735 () 21768..23060 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
HV049_RS25740 () 23071..26217 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
HV049_RS25745 () 26304..26744 + 441 WP_000758228.1 hypothetical protein -
HV049_RS25750 () 26871..29318 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
HV049_RS25755 () 29359..29556 + 198 WP_000843497.1 DUF2933 domain-containing protein -
HV049_RS25760 () 29590..30327 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
HV049_RS25765 () 30616..31065 - 450 WP_001023257.1 copper resistance protein -
HV049_RS25770 () 31299..33116 + 1818 WP_000925242.1 multicopper oxidase PcoA -
HV049_RS25775 () 33122..34012 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
HV049_RS25780 () 34052..34432 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
HV049_RS25785 () 34437..35366 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
HV049_RS25790 () 35421..36101 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
HV049_RS25795 () 36098..37498 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
HV049_RS25800 () 37715..38149 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
HV049_RS25805 () 38381..38560 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
HV049_RS25810 () 38621..40241 - 1621 Protein_33 ISL3 family transposase ISEc38 Transposase
HV049_RS25815 () 40303..40812 + 510 WP_031944101.1 aquaporin -
HV049_RS25820 () 40862..41359 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
HV049_RS25825 () 41691..42017 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
HV049_RS25830 () 42014..42727 + 714 WP_004152093.1 arsenical resistance protein ArsH -
HV049_RS25835 () 42736..43281 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
HV049_RS25840 () 43357..43719 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
HV049_RS25845 () 43744..45494 + 1751 Protein_40 arsenical pump-driving ATPase -
HV049_RS25850 () 45616..46152 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
HV049_RS25855 () 46185..46610 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
HV049_RS25860 () 46623..47912 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
HV049_RS25865 () 47960..49711 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
HV049_RS25870 () 49729..50091 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
HV049_RS25875 () 50141..50491 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
HV049_RS25880 () 50849..51118 + 270 WP_004152102.1 hypothetical protein -
HV049_RS25885 () 51106..51681 + 576 WP_004152103.1 hypothetical protein -
HV049_RS25890 () 51712..52206 + 495 WP_004152104.1 DNA-binding protein -
HV049_RS25895 () 52250..52618 + 369 WP_004152105.1 hypothetical protein -
HV049_RS25900 () 52652..52855 + 204 WP_004152106.1 hemolysin expression modulator Hha -
HV049_RS25905 () 52904..53161 + 258 WP_004152107.1 hypothetical protein -
HV049_RS25910 () 53237..53491 + 255 WP_004152108.1 hypothetical protein -
HV049_RS25915 () 53667..53933 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
HV049_RS25920 () 53921..54403 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
HV049_RS25925 () 54615..55961 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
HV049_RS25930 () 56462..57716 - 1255 Protein_57 IS3 family transposase ISKpn38 Transposase
HV049_RS25935 () 57804..58766 - 963 WP_004152113.1 M48 family metalloprotease -
HV049_RS25940 () 58753..59502 - 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
HV049_RS25945 () 59740..59937 - 198 WP_004152115.1 hypothetical protein -
HV049_RS25950 () 59937..62732 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
HV049_RS25955 () 62847..63416 - 570 WP_004152117.1 Spore protein SP21 VF
HV049_RS25960 () 63451..63732 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
HV049_RS25965 () 63976..64239 - 264 WP_004118208.1 hypothetical protein -
HV049_RS25970 () 64254..64517 + 264 WP_004118209.1 transposase -
HV049_RS25975 () 64462..64578 + 117 Protein_66 transposase domain-containing protein -
HV049_RS25980 () 64763..65460 + 698 Protein_67 IS1 family transposase IS1X3 Transposase
HV049_RS25985 () 65719..66699 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
HV049_RS25990 () 67281..67800 - 520 Protein_69 IS5 family transposase ISPst7 Transposase
HV049_RS25995 () 67908..68777 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
HV049_RS26000 () 68771..69781 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
HV049_RS26005 () 69790..70617 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
HV049_RS26010 () 70626..71489 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
HV049_RS26015 () 71486..72313 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
HV049_RS26020 () 72655..72963 + 309 Protein_75 IS5 family transposase ISThi1 Transposase
HV049_RS26025 () 73169..73873 - 705 WP_004217321.1 IS6 family transposase IS26 Transposase
HV049_RS26030 () 73885..74541 - 657 WP_000113282.1 Tetracycline repressor protein class D VF
HV049_RS26035 () 74637..75821 + 1185 WP_001039466.1 Tetracycline resistance protein, class B ARG
HV049_RS26040 () 75916..77025 + 1110 WP_000842134.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
HV049_RS26045 () 77047..77463 + 417 Protein_80 S-formylglutathione hydrolase -
HV049_RS26050 () 77515..78219 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HV049_RS26055 () 78280..79131 + 852 Protein_82 oligosaccharide MFS transporter -
HV049_RS26060 () 79196..80290 - 1095 WP_181575858.1 AAA family ATPase -
HV049_RS26065 () 80377..80637 - 261 WP_023304816.1 hypothetical protein -
HV049_RS26070 () 80934..81800 + 867 Protein_85 Beta-lactamase SHV-2 ARG
HV049_RS26075 () 81821..82587 - 767 Protein_86 DeoR/GlpR transcriptional regulator -
HV049_RS26080 () 82849..83751 + 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
HV049_RS26085 () 83904..84176 + 273 Protein_88 four-carbon acid sugar kinase family protein -
HV049_RS26090 () 84169..84789 + 621 WP_002210516.1 aldolase -
HV049_RS26095 () 84794..85447 + 654 Protein_90 2-oxo-tetronate isomerase VF
HV049_RS26100 () 85501..86205 - 705 WP_004217321.1 IS6 family transposase IS26 Transposase
HV049_RS26105 () 86282..86605 - 324 Protein_92 IS3 family transposase ISEc36 Transposase
HV049_RS26110 () 87082..87354 + 273 WP_000333416.1 His-Xaa-Ser system protein HxsD -
HV049_RS26115 () 87354..88742 + 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
HV049_RS26120 () 88735..89346 + 612 Protein_95 radical SAM protein -
HV049_RS26125 () 89362..90059 - 698 Protein_96 IS1 family transposase IS1R Transposase
HV049_RS26130 () 90193..91203 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
HV049_RS26135 () 91664..92746 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
HV049_RS26140 () 92868..95942 + 3075 WP_004152287.1 beta-galactosidase -
HV049_RS26145 () 95994..97247 + 1254 WP_003846917.1 lactose permease -
HV049_RS26150 () 97339..98308 + 970 Protein_101 IS5 family transposase IS903B Transposase
HV049_RS26155 () 98953..101262 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
HV049_RS26160 () 101266..102582 + 1317 WP_004152291.1 ATP-binding protein -
HV049_RS26165 () 102579..104774 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
HV049_RS26170 () 106166..107179 - 1014 WP_172870418.1 replication initiation protein -
HV049_RS26175 () 107338..107409 - 72 WP_071786674.1 RepA leader peptide Tap -
HV049_RS26180 () 107621..107890 - 270 WP_022631531.1 replication regulatory protein RepA -
HV049_RS26185 () 108026..108505 - 480 WP_162866173.1 Phospholipase D VF
HV049_RS26190 () 108681..108989 - 309 WP_181575847.1 hypothetical protein -
HV049_RS26195 () 108986..109636 - 651 WP_040120368.1 DUF2726 domain-containing protein -
HV049_RS26200 () 109692..110336 - 645 WP_181575848.1 hypothetical protein -
HV049_RS26205 () 110386..110580 - 195 WP_181575859.1 hypothetical protein -
HV049_RS26210 () 110572..111552 + 981 WP_057521290.1 IS5 family transposase ISKpn26 Transposase
HV049_RS26215 () 111702..111935 - 234 Protein_114 hypothetical protein -
HV049_RS26220 () 112096..112689 - 594 WP_004152380.1 fertility inhibition protein FinO -
HV049_RS26225 () 112761..113486 - 726 WP_114507340.1 type-F conjugative transfer system pilin acetylase TraX -
HV049_RS26230 () 113567..118825 - 5259 WP_181575849.1 Multifunctional conjugation protein TraI Relaxase
HV049_RS26235 () 118825..121107 - 2283 Protein_118 type IV conjugative transfer system coupling protein TraD -
HV049_RS26240 () 121234..121923 - 690 WP_181575850.1 hypothetical protein -
HV049_RS26245 () 122116..122847 - 732 WP_181575851.1 complement resistance protein TraT -
HV049_RS26250 () 123098..123700 - 603 WP_181575852.1 hypothetical protein -
HV049_RS26255 () 123723..126545 - 2823 WP_101455613.1 conjugal transfer mating pair stabilization protein TraG -
HV049_RS26260 () 126545..127924 - 1380 WP_181575853.1 conjugal transfer protein TraH -
HV049_RS26265 () 127902..128345 - 444 WP_014343488.1 F-type conjugal transfer protein TrbF -
HV049_RS26270 () 128391..128948 - 558 WP_013214031.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
HV049_RS26275 () 128920..129159 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
HV049_RS26280 () 129170..129922 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
HV049_RS26285 () 129943..130269 - 327 WP_004152676.1 hypothetical protein -
HV049_RS26290 () 130282..130530 - 249 WP_004152675.1 hypothetical protein -
HV049_RS26295 () 130508..130762 - 255 WP_004152674.1 conjugal transfer protein TrbE -
HV049_RS26300 () 130794..132749 - 1956 WP_181575854.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
HV049_RS26305 () 132808..133446 - 639 WP_004193871.1 type-F conjugative transfer system pilin assembly protein TrbC -
HV049_RS26310 () 133459..134448 - 990 WP_032408909.1 conjugal transfer pilus assembly protein TraU -
HV049_RS26315 () 134445..134846 - 402 WP_004194979.1 hypothetical protein -
HV049_RS26320 () 134881..135516 - 636 WP_181575855.1 type-F conjugative transfer system protein TraW -
HV049_RS26325 () 135516..135905 - 390 WP_117046014.1 type-F conjugative transfer system protein TrbI -
HV049_RS26330 () 135905..138544 - 2640 WP_032431388.1 type IV secretion system protein TraC -
HV049_RS26335 () 138616..139014 - 399 WP_074188112.1 hypothetical protein -
HV049_RS26340 () 139022..139310 - 289 Protein_139 hypothetical protein -
HV049_RS26345 () 139392..139796 - 405 WP_181575856.1 hypothetical protein -
HV049_RS26350 () 139863..140174 - 312 WP_181575857.1 hypothetical protein -
HV049_RS26355 () 140175..140393 - 219 WP_004195468.1 hypothetical protein -
HV049_RS26360 () 140716..141300 - 585 WP_032440547.1 type IV conjugative transfer system lipoprotein TraV -
HV049_RS26365 () 141373..142797 - 1425 WP_004233801.1 conjugal transfer protein TraB -
HV049_RS26370 () 142797..143537 - 741 WP_014386193.1 type-F conjugative transfer system secretin TraK -
HV049_RS26375 () 143524..144090 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
HV049_RS26380 () 144110..144415 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
HV049_RS26385 () 144429..144797 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
HV049_RS26390 () 144859..145065 - 207 WP_171773970.1 TraY domain-containing protein -
HV049_RS26395 () 145198..145917 - 720 WP_014386192.1 conjugal transfer protein -
HV049_RS26400 () 146110..146526 - 417 WP_072145360.1 relaxosome protein TraM -
HV049_RS26405 () 146917..147402 + 486 WP_004178063.1 hypothetical protein VF
HV049_RS26410 () 147435..147764 - 330 WP_014386191.1 hypothetical protein -
HV049_RS26415 () 147797..148618 - 822 WP_004182076.1 DUF945 domain-containing protein -
HV049_RS26420 () 149451..149864 - 414 WP_013023817.1 helix-turn-helix domain-containing protein -
HV049_RS26425 () 149865..150143 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
HV049_RS26430 () 150133..150452 - 320 Protein_157 type II toxin-antitoxin system RelE/ParE family toxin -
HV049_RS26435 () 150533..150757 - 225 WP_014386189.1 hypothetical protein -
HV049_RS26440 () 150768..150980 - 213 WP_014386188.1 hypothetical protein -
HV049_RS26445 () 151042..151368 - 327 WP_014386187.1 hypothetical protein -
HV049_RS26450 () 152005..152355 - 351 WP_014386186.1 hypothetical protein -
HV049_RS26455 () 152352..152624 - 273 WP_032408902.1 hypothetical protein -
HV049_RS26460 () 152814..153299 + 486 WP_014386185.1 hypothetical protein -
HV049_RS26465 () 153543..153701 - 159 WP_014386184.1 type I toxin-antitoxin system Hok family toxin -
HV049_RS26470 () 153898..154164 + 267 WP_014386183.1 DUF1778 domain-containing protein Antitoxin Detail
HV049_RS26475 () 154152..154643 + 492 WP_032408901.1 GNAT family N-acetyltransferase Toxin Detail
HV049_RS26480 () 155084..155335 - 252 WP_032408900.1 aldo/keto reductase -
HV049_RS26485 () 155532..157124 - 1593 Protein_168 IS66 family transposase ISEcl6 Transposase
HV049_RS26490 () 157155..157505 - 351 WP_014386180.1 IS66 family transposase ISKox1 Transposase
HV049_RS26495 () 157502..157942 - 441 WP_014386179.1 IS66 family transposase ISKox1 Transposase
HV049_RS26500 () 158204..158959 - 756 WP_032408898.1 DeoR/GlpR family DNA-binding transcription regulator -
HV049_RS26505 () 159187..160200 + 1014 WP_014386177.1 SIS domain-containing protein -
HV049_RS26510 () 160197..161108 + 912 WP_014386176.1 ROK family protein -
HV049_RS26515 () 161140..162528 + 1389 WP_014386175.1 sugar porter family MFS transporter -
HV049_RS26520 () 162692..162784 - 93 Protein_175 type II toxin-antitoxin system RelE/ParE family toxin -
HV049_RS26525 () 163015..163726 + 712 Protein_176 IS481 family transposase ISKpn28 Transposase
HV049_RS26530 () 164167..165330 - 1164 WP_001471748.1 alpha-hydroxy-acid oxidizing protein -
HV049_RS26535 () 165403..166653 - 1251 WP_014386172.1 NAD(P)/FAD-dependent oxidoreductase -
HV049_RS26540 () 166784..167602 - 819 WP_014386171.1 ABC transporter permease -
HV049_RS26545 () 167604..168458 - 855 WP_000197183.1 ABC transporter permease -
HV049_RS26550 () 168524..169555 - 1032 WP_001327073.1 ABC transporter substrate-binding protein -
HV049_RS26555 () 169894..170856 + 963 WP_000952529.1 LysR family transcriptional regulator -
HV049_RS26560 () 170868..171797 - 930 WP_014386170.1 glyoxylate/hydroxypyruvate reductase A -
HV049_RS26565 () 171794..172243 - 450 WP_000082700.1 3-dehydroquinate dehydratase -
HV049_RS26570 () 172256..172870 - 615 WP_014386169.1 glutathione S-transferase N-terminal domain-containing protein -
HV049_RS26575 () 172867..173862 - 996 WP_000611945.1 Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsC VF
HV049_RS26580 () 173869..175017 - 1149 WP_014386168.1 Spermidine/putrescine import ATP-binding protein PotA VF
HV049_RS26585 () 175188..176345 - 1158 WP_032408895.1 acetylornithine deacetylase -
HV049_RS26590 () 176361..177035 - 675 WP_014386166.1 DUF1028 domain-containing protein -
HV049_RS26595 () 177040..177474 - 435 WP_000103648.1 RidA family protein -
HV049_RS26600 () 177794..178024 + 231 WP_032408893.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
HV049_RS26605 () 178021..178437 + 417 WP_014386165.1 PIN domain-containing protein Toxin Detail
HV049_RS26610 () 178760..179728 + 969 WP_074422984.1 IS5 family transposase IS903B Transposase
HV049_RS26615 () 179908..180282 - 375 WP_032408891.1 hypothetical protein -
HV049_RS26620 () 180338..180664 - 327 WP_004152639.1 hypothetical protein -
HV049_RS26625 () 180661..181389 - 729 WP_014386162.1 plasmid SOS inhibition protein A -
HV049_RS26630 () 181386..181817 - 432 WP_014386161.1 conjugation system SOS inhibitor PsiB -
HV049_RS26635 () 181862..183919 - 2058 WP_014386160.1 ParB/RepB/Spo0J family partition protein -
HV049_RS26640 () 183989..184237 - 249 WP_014386159.1 DUF905 domain-containing protein -
HV049_RS26645 () 184286..184834 - 549 WP_117085282.1 single-stranded DNA-binding protein -
HV049_RS26650 () 185669..186232 - 564 WP_004152756.1 methyltransferase -
HV049_RS26655 () 186280..187635 - 1356 WP_014386157.1 DUF3560 domain-containing protein -
HV049_RS26660 () 187687..187917 - 231 WP_001568051.1 hypothetical protein -
HV049_RS26665 () 188009..188236 - 228 WP_004178072.1 hypothetical protein -
HV049_RS26670 () 189017..189334 - 318 WP_004118473.1 hypothetical protein -
HV049_RS26675 () 189369..189623 - 255 WP_004152754.1 DNA polymerase III subunit theta -
HV049_RS26680 () 189860..190285 - 426 WP_004118478.1 antirestriction protein -
HV049_RS26685 () 190806..191036 - 231 WP_004118481.1 hypothetical protein -
HV049_RS26690 () 191250..191675 + 426 WP_004182047.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
HV049_RS26695 () 191675..192946 + 1272 WP_014386156.1 Y-family DNA polymerase -
HV049_RS26700 () 193025..193240 + 216 Protein_211 type II toxin-antitoxin system Phd/YefM family antitoxin -
HV049_RS26705 () 193263..194461 - 1199 Protein_212 IS200-IS605 family transposase IS609 Transposase
HV049_RS26710 () 195770..196741 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
HV049_RS26715 () 196741..197907 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance