NZ_CP0568791..199477

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 199477 bp
Accession: NZ_CP056879        Location: 1..199477         Organism: Klebsiella pneumoniae strain RHBSTW-00066       Replicon: plasmid pRHBSTW-00066_2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV051_RS25650 () 1..1011 + 1011 WP_000200070.1 RepB family plasmid replication initiator protein -
HV051_RS25655 () 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
HV051_RS25660 () 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
HV051_RS25665 () 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
HV051_RS25670 () 4917..5885 + 969 WP_011977741.1 IS5 family transposase -
HV051_RS25675 () 6558..6815 - 258 WP_004197688.1 hypothetical protein -
HV051_RS25680 () 7435..8871 + 1437 WP_080895248.1 EAL domain-containing protein -
HV051_RS25685 () 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
HV051_RS25690 () 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
HV051_RS25695 () 13343..14040 - 698 Protein_9 IS1 family transposase -
HV051_RS25705 () 15529..16013 + 485 Protein_11 IS1 family transposase -
HV051_RS25710 () 16029..16571 + 543 Protein_12 transposase -
HV051_RS25715 () 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
HV051_RS25720 () 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
HV051_RS25725 () 19017..19697 - 681 WP_001572351.1 copper/silver response regulator transcription factor SilR -
HV051_RS25730 () 19887..21272 + 1386 WP_000475512.1 Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC -
HV051_RS25735 () 21301..21654 + 354 WP_001246153.1 cation efflux system protein CusF -
HV051_RS25740 () 21768..23060 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
HV051_RS25745 () 23071..26217 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
HV051_RS25750 () 26304..26744 + 441 WP_000758228.1 hypothetical protein -
HV051_RS25755 () 26871..29318 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
HV051_RS25760 () 29359..29556 + 198 WP_000843497.1 DUF2933 domain-containing protein -
HV051_RS25765 () 29590..30327 - 738 WP_004118669.1 peptidoglycan DD-metalloendopeptidase family protein -
HV051_RS25770 () 30616..31065 - 450 WP_001023257.1 copper resistance protein -
HV051_RS25775 () 31299..33116 + 1818 WP_000925242.1 multicopper oxidase PcoA -
HV051_RS25780 () 33122..34012 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
HV051_RS25785 () 34052..34432 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
HV051_RS25790 () 34437..35366 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
HV051_RS25795 () 35421..36101 + 681 WP_001188930.1 copper response regulator transcription factor PcoR -
HV051_RS25800 () 36098..37498 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
HV051_RS25805 () 37715..38149 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
HV051_RS25810 () 38381..38560 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
HV051_RS25815 () 38621..40241 - 1621 Protein_33 ISL3 family transposase -
HV051_RS25820 () 40303..40812 + 510 WP_031944101.1 aquaporin -
HV051_RS25825 () 40862..41359 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
HV051_RS25830 () 41691..42017 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
HV051_RS25835 () 42014..42727 + 714 WP_004152093.1 arsenical resistance protein ArsH -
HV051_RS25840 () 42736..43281 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
HV051_RS25845 () 43357..43719 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
HV051_RS25850 () 43744..45494 + 1751 Protein_40 arsenical pump-driving ATPase -
HV051_RS25855 () 45616..46152 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
HV051_RS25860 () 46185..46610 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
HV051_RS25865 () 46623..47912 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
HV051_RS25870 () 47960..49711 - 1752 WP_004152099.1 arsenite efflux transporter ATPase subunit ArsA -
HV051_RS25875 () 49729..50091 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
HV051_RS25880 () 50141..50491 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
HV051_RS25885 () 50849..51118 + 270 WP_004152102.1 hypothetical protein -
HV051_RS25890 () 51106..51681 + 576 WP_004152103.1 hypothetical protein -
HV051_RS25895 () 51712..52206 + 495 WP_004152104.1 DNA-binding protein -
HV051_RS25900 () 52250..52618 + 369 WP_004152105.1 hypothetical protein -
HV051_RS25905 () 52652..52855 + 204 WP_004152106.1 hemolysin expression modulator Hha -
HV051_RS25910 () 52904..53161 + 258 WP_004152107.1 hypothetical protein -
HV051_RS25915 () 53237..53491 + 255 WP_004152108.1 hypothetical protein -
HV051_RS25920 () 53667..53933 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
HV051_RS25925 () 53921..54403 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
HV051_RS25930 () 54615..55961 + 1347 WP_020314316.1 ISNCY family transposase -
HV051_RS25935 () 56462..57716 - 1255 Protein_57 IS3 family transposase -
HV051_RS25940 () 57804..58766 - 963 WP_004152113.1 M48 family metalloprotease -
HV051_RS25945 () 58753..59502 - 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
HV051_RS25950 () 59740..59937 - 198 WP_004152115.1 hypothetical protein -
HV051_RS25955 () 59937..62732 - 2796 WP_004152116.1 heat shock survival AAA family ATPase ClpK -
HV051_RS25960 () 62847..63416 - 570 WP_004152117.1 small heat shock protein sHSP20 -
HV051_RS25965 () 63451..63732 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
HV051_RS25970 () 63976..64239 - 264 WP_004118208.1 hypothetical protein -
HV051_RS25975 () 64254..64517 + 264 WP_004118209.1 transposase -
HV051_RS25980 () 64462..64578 + 117 Protein_66 transposase domain-containing protein -
HV051_RS25985 () 64763..65460 + 698 Protein_67 IS1 family transposase -
HV051_RS25990 () 65719..66699 + 981 WP_000019473.1 IS5-like element ISKpn26 family transposase -
HV051_RS25995 () 67281..67800 - 520 Protein_69 IS5-like element ISPre2 family transposase -
HV051_RS26000 () 67908..68777 - 870 WP_004152692.1 LysR family transcriptional regulator -
HV051_RS26005 () 68771..69781 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
HV051_RS26010 () 69790..70617 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
HV051_RS26015 () 70626..71489 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
HV051_RS26020 () 71486..72313 - 828 WP_004153729.1 phosphonate ABC transporter ATP-binding protein -
HV051_RS26025 () 72655..72963 + 309 Protein_75 IS5/IS1182 family transposase -
HV051_RS26030 () 73169..73873 - 705 WP_004217321.1 IS6-like element IS26 family transposase -
HV051_RS26035 () 73885..74541 - 657 WP_000113282.1 tetracycline resistance transcriptional repressor TetR(D) -
HV051_RS26040 () 74637..75821 + 1185 WP_001039466.1 tetracycline efflux MFS transporter Tet(D) -
HV051_RS26045 () 75916..77025 + 1110 WP_000842134.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
HV051_RS26050 () 77047..77463 + 417 Protein_80 S-formylglutathione hydrolase -
HV051_RS26055 () 77515..78219 - 705 WP_001067855.1 IS6-like element IS26 family transposase -
HV051_RS26060 () 78280..79161 + 882 Protein_82 oligosaccharide MFS transporter -
HV051_RS26065 () 79192..80280 - 1089 WP_001620097.1 AAA family ATPase -
HV051_RS26070 () 80367..80627 - 261 WP_004176262.1 hypothetical protein -
HV051_RS26075 () 80925..81785 + 861 WP_002904004.1 class A extended-spectrum beta-lactamase SHV-12 -
HV051_RS26080 () 81806..82567 - 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
HV051_RS26085 () 82829..83731 + 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
HV051_RS26090 () 83743..84995 + 1253 Protein_88 four-carbon acid sugar kinase family protein -
HV051_RS26095 () 84988..85608 + 621 WP_002210516.1 aldolase -
HV051_RS26100 () 85613..86266 + 654 Protein_90 TIM barrel protein -
HV051_RS26105 () 86320..87024 - 705 WP_004217321.1 IS6-like element IS26 family transposase -
HV051_RS26110 () 87101..87424 - 324 Protein_92 transposase -
HV051_RS26115 () 87901..88173 + 273 WP_000333416.1 His-Xaa-Ser system protein HxsD -
HV051_RS26120 () 88173..89561 + 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
HV051_RS26125 () 89554..90165 + 612 Protein_95 radical SAM protein -
HV051_RS26130 () 90181..90878 - 698 Protein_96 IS1 family transposase -
HV051_RS26135 () 91012..92022 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
HV051_RS26140 () 92483..93565 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
HV051_RS26145 () 93687..96761 + 3075 WP_004152287.1 beta-galactosidase -
HV051_RS26150 () 96813..98066 + 1254 WP_003846917.1 lactose permease -
HV051_RS26155 () 98158..99127 + 970 Protein_101 IS5-like element IS903B family transposase -
HV051_RS26160 () 99772..102081 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
HV051_RS26165 () 102085..103401 + 1317 WP_004152291.1 ATP-binding protein -
HV051_RS26170 () 103398..105593 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
HV051_RS26175 () 106985..107998 - 1014 WP_172870418.1 replication initiation protein -
HV051_RS26180 () 108157..108228 - 72 WP_071786674.1 RepA leader peptide Tap -
HV051_RS26185 () 108440..108709 - 270 WP_022631531.1 replication regulatory protein RepA -
HV051_RS26190 () 108845..109324 - 480 WP_162866173.1 phospholipase D family protein -
HV051_RS26195 () 109500..109808 - 309 WP_181575847.1 hypothetical protein -
HV051_RS26200 () 109805..110455 - 651 WP_040120368.1 DUF2726 domain-containing protein -
HV051_RS26205 () 110511..111155 - 645 WP_181575848.1 hypothetical protein -
HV051_RS26210 () 111205..111399 - 195 WP_181575859.1 hypothetical protein -
HV051_RS26215 () 111391..112371 + 981 WP_057521290.1 IS5-like element ISKpn26 family transposase -
HV051_RS26220 () 112521..112754 - 234 Protein_114 hypothetical protein -
HV051_RS26225 () 112915..113508 - 594 WP_004152380.1 fertility inhibition protein FinO -
HV051_RS26230 () 113580..114305 - 726 WP_114507340.1 type-F conjugative transfer system pilin acetylase TraX -
HV051_RS26235 () 114386..119644 - 5259 WP_181575849.1 conjugative transfer relaxase/helicase TraI -
HV051_RS26240 () 119644..121926 - 2283 Protein_118 type IV conjugative transfer system coupling protein TraD -
HV051_RS26245 () 122053..122742 - 690 WP_181575850.1 hypothetical protein -
HV051_RS26250 () 122935..123666 - 732 WP_181575851.1 complement resistance protein TraT -
HV051_RS26255 () 123917..124519 - 603 WP_181575852.1 hypothetical protein -
HV051_RS26260 () 124542..127364 - 2823 WP_101455613.1 conjugal transfer mating pair stabilization protein TraG -
HV051_RS26265 () 127364..128743 - 1380 WP_181575853.1 conjugal transfer protein TraH -
HV051_RS26270 () 128721..129164 - 444 WP_014343488.1 F-type conjugal transfer protein TrbF -
HV051_RS26275 () 129210..129767 - 558 WP_013214031.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
HV051_RS26280 () 129739..129978 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
HV051_RS26285 () 129989..130741 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
HV051_RS26290 () 130762..131088 - 327 WP_004152676.1 hypothetical protein -
HV051_RS26295 () 131101..131349 - 249 WP_004152675.1 hypothetical protein -
HV051_RS26300 () 131327..131581 - 255 WP_004152674.1 conjugal transfer protein TrbE -
HV051_RS26305 () 131613..133568 - 1956 WP_181575854.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
HV051_RS26310 () 133627..134265 - 639 WP_004193871.1 type-F conjugative transfer system pilin assembly protein TrbC -
HV051_RS26315 () 134278..135267 - 990 WP_032408909.1 conjugal transfer pilus assembly protein TraU -
HV051_RS26320 () 135264..135665 - 402 WP_004194979.1 hypothetical protein -
HV051_RS26325 () 135700..136335 - 636 WP_181575855.1 type-F conjugative transfer system protein TraW -
HV051_RS26330 () 136335..136724 - 390 WP_117046014.1 type-F conjugative transfer system protein TrbI -
HV051_RS26335 () 136724..139363 - 2640 WP_032431388.1 type IV secretion system protein TraC -
HV051_RS26340 () 139435..139833 - 399 WP_074188112.1 hypothetical protein -
HV051_RS26345 () 139841..140129 - 289 Protein_139 hypothetical protein -
HV051_RS26350 () 140211..140615 - 405 WP_181575856.1 hypothetical protein -
HV051_RS26355 () 140682..140993 - 312 WP_181575857.1 hypothetical protein -
HV051_RS26360 () 140994..141212 - 219 WP_004195468.1 hypothetical protein -
HV051_RS26365 () 141535..142119 - 585 WP_032440547.1 type IV conjugative transfer system lipoprotein TraV -
HV051_RS26370 () 142192..143616 - 1425 WP_004233801.1 conjugal transfer protein TraB -
HV051_RS26375 () 143616..144356 - 741 WP_014386193.1 type-F conjugative transfer system secretin TraK -
HV051_RS26380 () 144343..144909 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
HV051_RS26385 () 144929..145234 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
HV051_RS26390 () 145248..145616 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
HV051_RS26395 () 145678..145884 - 207 WP_171773970.1 TraY domain-containing protein -
HV051_RS26400 () 146017..146736 - 720 WP_014386192.1 conjugal transfer protein -
HV051_RS26405 () 146929..147345 - 417 WP_072145360.1 relaxosome protein TraM -
HV051_RS26410 () 147736..148221 + 486 WP_004178063.1 transglycosylase SLT domain-containing protein -
HV051_RS26415 () 148254..148583 - 330 WP_014386191.1 hypothetical protein -
HV051_RS26420 () 148616..149437 - 822 WP_004182076.1 DUF945 domain-containing protein -
HV051_RS26425 () 150270..150683 - 414 WP_013023817.1 helix-turn-helix domain-containing protein -
HV051_RS26430 () 150684..150962 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
HV051_RS26435 () 150952..151271 - 320 Protein_157 type II toxin-antitoxin system RelE/ParE family toxin -
HV051_RS26440 () 151352..151576 - 225 WP_014386189.1 hypothetical protein -
HV051_RS26445 () 151587..151799 - 213 WP_014386188.1 hypothetical protein -
HV051_RS26450 () 151861..152187 - 327 WP_014386187.1 hypothetical protein -
HV051_RS26455 () 152824..153174 - 351 WP_014386186.1 hypothetical protein -
HV051_RS26460 () 153171..153443 - 273 WP_032408902.1 hypothetical protein -
HV051_RS26465 () 153633..154118 + 486 WP_014386185.1 hypothetical protein -
HV051_RS26470 () 154362..154520 - 159 WP_014386184.1 type I toxin-antitoxin system Hok family toxin -
HV051_RS26475 () 154717..154983 + 267 WP_014386183.1 DUF1778 domain-containing protein Antitoxin Detail
HV051_RS26480 () 154971..155462 + 492 WP_032408901.1 GNAT family N-acetyltransferase Toxin Detail
HV051_RS26485 () 155903..156154 - 252 WP_032408900.1 aldo/keto reductase -
HV051_RS26490 () 156351..157943 - 1593 Protein_168 IS66 family transposase -
HV051_RS26495 () 157974..158324 - 351 WP_014386180.1 IS66 family insertion sequence element accessory protein TnpB -
HV051_RS26500 () 158321..158761 - 441 WP_014386179.1 IS66 family insertion sequence hypothetical protein -
HV051_RS26505 () 159023..159778 - 756 WP_032408898.1 DeoR/GlpR family DNA-binding transcription regulator -
HV051_RS26510 () 160006..161019 + 1014 WP_014386177.1 SIS domain-containing protein -
HV051_RS26515 () 161016..161927 + 912 WP_014386176.1 ROK family protein -
HV051_RS26520 () 161959..163347 + 1389 WP_014386175.1 sugar porter family MFS transporter -
HV051_RS26525 () 163511..163603 - 93 Protein_175 type II toxin-antitoxin system RelE/ParE family toxin -
HV051_RS26530 () 163834..164545 + 712 Protein_176 transposase -
HV051_RS26535 () 164986..166149 - 1164 WP_001471748.1 alpha-hydroxy-acid oxidizing protein -
HV051_RS26540 () 166222..167472 - 1251 WP_014386172.1 NAD(P)/FAD-dependent oxidoreductase -
HV051_RS26545 () 167603..168421 - 819 WP_014386171.1 ABC transporter permease -
HV051_RS26550 () 168423..169277 - 855 WP_000197183.1 ABC transporter permease -
HV051_RS26555 () 169343..170374 - 1032 WP_001327073.1 ABC transporter substrate-binding protein -
HV051_RS26560 () 170713..171675 + 963 WP_000952529.1 LysR family transcriptional regulator -
HV051_RS26565 () 171687..172616 - 930 WP_014386170.1 glyoxylate/hydroxypyruvate reductase A -
HV051_RS26570 () 172613..173062 - 450 WP_000082700.1 3-dehydroquinate dehydratase -
HV051_RS26575 () 173075..173689 - 615 WP_014386169.1 glutathione S-transferase N-terminal domain-containing protein -
HV051_RS26580 () 173686..174681 - 996 WP_000611945.1 NAD(P)H-quinone oxidoreductase -
HV051_RS26585 () 174688..175836 - 1149 WP_014386168.1 ABC transporter ATP-binding protein -
HV051_RS26590 () 176007..177164 - 1158 WP_032408895.1 acetylornithine deacetylase -
HV051_RS26595 () 177180..177854 - 675 WP_014386166.1 DUF1028 domain-containing protein -
HV051_RS26600 () 177859..178293 - 435 WP_000103648.1 RidA family protein -
HV051_RS26605 () 178613..178843 + 231 WP_032408893.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
HV051_RS26610 () 178840..179256 + 417 WP_014386165.1 PIN domain-containing protein Toxin Detail
HV051_RS26615 () 179579..180547 + 969 WP_074422984.1 IS5 family transposase -
HV051_RS26620 () 180727..181101 - 375 WP_032408891.1 hypothetical protein -
HV051_RS26625 () 181157..181483 - 327 WP_004152639.1 hypothetical protein -
HV051_RS26630 () 181480..182208 - 729 WP_014386162.1 plasmid SOS inhibition protein A -
HV051_RS26635 () 182205..182636 - 432 WP_014386161.1 conjugation system SOS inhibitor PsiB -
HV051_RS26640 () 182681..184738 - 2058 WP_014386160.1 ParB/RepB/Spo0J family partition protein -
HV051_RS26645 () 184808..185056 - 249 WP_014386159.1 DUF905 domain-containing protein -
HV051_RS26650 () 185105..185653 - 549 WP_117085282.1 single-stranded DNA-binding protein -
HV051_RS26655 () 186488..187051 - 564 WP_004152756.1 methyltransferase -
HV051_RS26660 () 187099..188454 - 1356 WP_014386157.1 DUF3560 domain-containing protein -
HV051_RS26665 () 188506..188736 - 231 WP_001568051.1 hypothetical protein -
HV051_RS26670 () 188828..189055 - 228 WP_004178072.1 hypothetical protein -
HV051_RS26675 () 189836..190153 - 318 WP_004118473.1 hypothetical protein -
HV051_RS26680 () 190188..190442 - 255 WP_004152754.1 DNA polymerase III subunit theta -
HV051_RS26685 () 190679..191104 - 426 WP_004118478.1 antirestriction protein -
HV051_RS26690 () 191625..191855 - 231 WP_004118481.1 hypothetical protein -
HV051_RS26695 () 192069..192494 + 426 WP_004182047.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
HV051_RS26700 () 192494..193765 + 1272 WP_014386156.1 Y-family DNA polymerase -
HV051_RS26705 () 193844..194059 + 216 Protein_211 type II toxin-antitoxin system Phd/YefM family antitoxin -
HV051_RS26710 () 194082..195280 - 1199 Protein_212 IS200/IS605 family element transposase accessory protein TnpB -
HV051_RS26715 () 196589..197560 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
HV051_RS26720 () 197560..198726 - 1167 WP_000523813.1 plasmid-partitioning protein SopA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance