MGE detailed information
MGE type: Conjugative plasmid MGE length: 122007 bp
Accession: NZ_CP055180 Location: 1..122007 Organism: Shigella flexneri strain STEFF_18 Replicon: plasmid unnamed1
Accession: NZ_CP055180 Location: 1..122007 Organism: Shigella flexneri strain STEFF_18 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ46_RS23540 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| HUZ46_RS23545 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| HUZ46_RS23550 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| HUZ46_RS23555 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| HUZ46_RS23560 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| HUZ46_RS23565 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| HUZ46_RS23570 (6637) | 6637..7334 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| HUZ46_RS23575 (7351) | 7351..7548 | - | 198 | Protein_7 | colicin V | - |
| HUZ46_RS23580 (7526) | 7526..7762 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| HUZ46_RS23585 (8226) | 8226..8507 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| HUZ46_RS23590 (8680) | 8680..8847 | + | 168 | Protein_10 | colicin-B | - |
| HUZ46_RS23595 (8865) | 8865..9392 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| HUZ46_RS23600 (9636) | 9636..10451 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| HUZ46_RS23605 (10501) | 10501..10854 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| HUZ46_RS23610 (11032) | 11032..11823 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| HUZ46_RS23615 (11820) | 11820..12509 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| HUZ46_RS23620 (12553) | 12553..12903 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| HUZ46_RS23625 (13448) | 13448..14536 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| HUZ46_RS23630 (14538) | 14538..16763 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| HUZ46_RS23635 (16813) | 16813..17712 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| HUZ46_RS23640 (17702) | 17702..17992 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| HUZ46_RS23645 (18288) | 18288..18518 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| HUZ46_RS23650 (18515) | 18515..18931 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HUZ46_RS23655 (19093) | 19093..21231 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| HUZ46_RS23660 (21585) | 21585..21842 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| HUZ46_RS23665 (21842) | 21842..22432 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| HUZ46_RS23670 (22695) | 22695..24155 | + | 1461 | WP_202745975.1 | AAA family ATPase | - |
| HUZ46_RS23675 (24443) | 24443..25060 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| HUZ46_RS23680 (25353) | 25353..26432 | - | 1080 | WP_001089727.1 | permease | - |
| HUZ46_RS23685 (26537) | 26537..26860 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| HUZ46_RS23690 (27021) | 27021..27341 | + | 321 | Protein_30 | NAD(P)H-dependent oxidoreductase | - |
| HUZ46_RS23695 (27394) | 27394..28098 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ46_RS23700 (28164) | 28164..29507 | + | 1344 | Protein_32 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ46_RS23705 (29558) | 29558..30262 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ46_RS23710 (30328) | 30328..30612 | + | 285 | Protein_34 | IS6 family transposase IS26 | Transposase |
| HUZ46_RS23715 (30802) | 30802..31617 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HUZ46_RS23720 (31768) | 31768..32472 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ46_RS23725 (32920) | 32920..33933 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ46_RS23730 (34089) | 34089..34562 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| HUZ46_RS23735 (34632) | 34632..35336 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ46_RS23740 (35390) | 35390..35704 | + | 315 | Protein_40 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HUZ46_RS23745 (35707) | 35707..38673 | + | 2967 | WP_072794601.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| HUZ46_RS23750 (38752) | 38752..39756 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| HUZ46_RS23755 (40028) | 40028..40114 | - | 87 | Protein_43 | Arm DNA-binding domain-containing protein | - |
| HUZ46_RS23760 (40444) | 40444..41259 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| HUZ46_RS23765 (41320) | 41320..42123 | + | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HUZ46_RS23770 (42123) | 42123..42959 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| HUZ46_RS23775 (43190) | 43190..44050 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HUZ46_RS23780 (44233) | 44233..44790 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUZ46_RS23785 (44954) | 44954..45172 | + | 219 | WP_001143771.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ46_RS23790 (45354) | 45354..46616 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| HUZ46_RS23795 (46872) | 46872..47747 | + | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| HUZ46_RS23800 (47794) | 47794..48087 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| HUZ46_RS23805 (48152) | 48152..50371 | + | 2220 | Protein_53 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ46_RS23810 (50448) | 50448..51152 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ46_RS23815 (51218) | 51218..51763 | + | 546 | Protein_55 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ46_RS23820 (51799) | 51799..52214 | - | 416 | Protein_56 | IS1-like element IS1B family transposase | - |
| HUZ46_RS23825 (52463) | 52463..52864 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HUZ46_RS23830 (52797) | 52797..53054 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HUZ46_RS23835 (53147) | 53147..53800 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HUZ46_RS23840 (54739) | 54739..55596 | - | 858 | WP_239612969.1 | incFII family plasmid replication initiator RepA | - |
| HUZ46_RS23845 (55589) | 55589..56071 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| HUZ46_RS23850 (56064) | 56064..56111 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| HUZ46_RS23855 (56102) | 56102..56353 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| HUZ46_RS23860 (56370) | 56370..56627 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| HUZ46_RS23865 (56911) | 56911..57060 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (57104) | 57104..57165 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (57104) | 57104..57165 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (57104) | 57104..57165 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (57104) | 57104..57165 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| HUZ46_RS23870 (57421) | 57421..57495 | - | 75 | Protein_66 | endonuclease | - |
| HUZ46_RS23875 (57741) | 57741..57953 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| HUZ46_RS23880 (58089) | 58089..58649 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| HUZ46_RS23885 (58752) | 58752..59612 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| HUZ46_RS23890 (59671) | 59671..60417 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| HUZ46_RS23895 (60437) | 60437..65707 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| HUZ46_RS23900 (65789) | 65789..66016 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| HUZ46_RS23905 (66016) | 66016..66414 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HUZ46_RS23910 (66423) | 66423..68576 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| HUZ46_RS23915 (68829) | 68829..69560 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| HUZ46_RS23920 (69592) | 69592..70089 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| HUZ46_RS23925 (70105) | 70105..72927 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HUZ46_RS23930 (72924) | 72924..74297 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| HUZ46_RS23935 (74297) | 74297..74677 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| HUZ46_RS23940 (74664) | 74664..75005 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| HUZ46_RS23945 (74935) | 74935..75480 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HUZ46_RS23950 (75467) | 75467..75751 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HUZ46_RS23955 (75832) | 75832..76146 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| HUZ46_RS23960 (76148) | 76148..76495 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| HUZ46_RS23965 (76511) | 76511..77254 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HUZ46_RS23970 (77247) | 77247..77504 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| HUZ46_RS23975 (77531) | 77531..79339 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HUZ46_RS23980 (79336) | 79336..79974 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HUZ46_RS23985 (79983) | 79983..80975 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| HUZ46_RS23990 (80972) | 80972..81604 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| HUZ46_RS23995 (81601) | 81601..81987 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| HUZ46_RS24000 (81984) | 81984..84611 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| HUZ46_RS24005 (84771) | 84771..84992 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| HUZ46_RS24010 (85127) | 85127..85642 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HUZ46_RS24015 (85639) | 85639..85890 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| HUZ46_RS24020 (85902) | 85902..86099 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| HUZ46_RS24025 (86086) | 86086..86676 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| HUZ46_RS24030 (86666) | 86666..88093 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HUZ46_RS24035 (88093) | 88093..88821 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| HUZ46_RS24040 (88808) | 88808..89197 | - | 390 | Protein_100 | type IV conjugative transfer system protein TraE | - |
| HUZ46_RS24045 (89291) | 89291..90519 | + | 1229 | WP_089541817.1 | IS3 family transposase IS2 | Transposase |
| HUZ46_RS24050 (90531) | 90531..90710 | - | 180 | Protein_102 | TraE/TraK family type IV conjugative transfer system protein | - |
| HUZ46_RS24055 (90732) | 90732..91043 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HUZ46_RS24060 (91058) | 91058..91423 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| HUZ46_RS24065 (91456) | 91456..91857 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| HUZ46_RS24070 (91950) | 91950..92639 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| HUZ46_RS24075 (92826) | 92826..93209 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HUZ46_RS24080 (93530) | 93530..94132 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| HUZ46_RS24085 (94429) | 94429..95250 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| HUZ46_RS24090 (95368) | 95368..95655 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HUZ46_RS24095 (95680) | 95680..95886 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| HUZ46_RS24100 (95956) | 95956..96128 | + | 173 | Protein_112 | hypothetical protein | - |
| HUZ46_RS24105 (96126) | 96126..96356 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| HUZ46_RS24110 (96576) | 96576..96701 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUZ46_RS24115 (96643) | 96643..96792 | - | 150 | Protein_115 | plasmid maintenance protein Mok | - |
| - (96778) | 96778..97002 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (96778) | 96778..97002 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (96778) | 96778..97002 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (96778) | 96778..97002 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| HUZ46_RS24120 (96814) | 96814..97002 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| HUZ46_RS24125 (96971) | 96971..97733 | - | 763 | Protein_117 | plasmid SOS inhibition protein A | - |
| HUZ46_RS24130 (97730) | 97730..98164 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| HUZ46_RS24135 (98219) | 98219..98416 | - | 198 | Protein_119 | hypothetical protein | - |
| HUZ46_RS24140 (98444) | 98444..98677 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| HUZ46_RS24145 (98745) | 98745..99284 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| HUZ46_RS24150 (99310) | 99310..99516 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| HUZ46_RS24155 (99586) | 99586..99666 | + | 81 | Protein_123 | hypothetical protein | - |
| HUZ46_RS24160 (99849) | 99849..100018 | - | 170 | Protein_124 | hypothetical protein | - |
| HUZ46_RS24165 (100655) | 100655..101626 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HUZ46_RS24170 (101626) | 101626..102792 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| HUZ46_RS24180 (104274) | 104274..106469 | - | 2196 | WP_175267602.1 | Ferric aerobactin receptor | VF |
| HUZ46_RS24185 (106501) | 106501..107834 | - | 1334 | Protein_129 | L-lysine N6-monooxygenase | VF |
| HUZ46_RS24190 (107831) | 107831..109573 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| HUZ46_RS24195 (109573) | 109573..110520 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| HUZ46_RS24200 (110521) | 110521..112245 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| HUZ46_RS24205 (112381) | 112381..113574 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| HUZ46_RS24210 (113954) | 113954..114334 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| HUZ46_RS24215 (114675) | 114675..115088 | - | 414 | Protein_135 | phosphopyruvate hydratase | - |
| HUZ46_RS24220 (115086) | 115086..115343 | + | 258 | Protein_136 | Tn3 family transposase | - |
| HUZ46_RS24225 (115577) | 115577..116434 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| HUZ46_RS24230 (116431) | 116431..117288 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| HUZ46_RS24235 (117285) | 117285..118112 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| HUZ46_RS24240 (118112) | 118112..119026 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| HUZ46_RS24245 (119382) | 119382..120079 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| HUZ46_RS24250 (120259) | 120259..120772 | - | 514 | Protein_142 | DUF4113 domain-containing protein | - |
| HUZ46_RS24255 (120833) | 120833..120937 | - | 105 | Protein_143 | AAA family ATPase | - |
| HUZ46_RS24260 (120939) | 120939..121262 | - | 324 | Protein_144 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|