MGE detailed information
MGE type: Conjugative plasmid MGE length: 128954 bp
Accession: NZ_CP054220 Location: 1..128954 Organism: Escherichia coli strain EcPF18 Replicon: plasmid p1
Accession: NZ_CP054220 Location: 1..128954 Organism: Escherichia coli strain EcPF18 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HR075_RS24235 () | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| HR075_RS24240 () | 1263..2003 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| HR075_RS24245 () | 2124..2312 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| HR075_RS24250 () | 2679..3848 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| HR075_RS24255 () | 4074..4249 | - | 176 | Protein_4 | IS3 family transposase | - |
| HR075_RS24260 () | 4695..4967 | - | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| HR075_RS24265 () | 5492..5928 | - | 437 | Protein_6 | IS3 family transposase IS2 | Transposase |
| HR075_RS24270 () | 6210..8180 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| HR075_RS24275 () | 8187..8978 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| HR075_RS24280 () | 9041..9649 | - | 609 | Protein_9 | IS66 family transposase ISEc22 | Transposase |
| HR075_RS24285 () | 9717..10496 | - | 780 | WP_001323403.1 | IS21 family transposase IS100kyp | Transposase |
| HR075_RS24290 () | 10496..11518 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| HR075_RS24295 () | 11604..12549 | - | 946 | Protein_12 | IS66 family transposase ISEc8 | Transposase |
| HR075_RS24300 () | 12598..12945 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| HR075_RS24305 () | 12942..13346 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| HR075_RS24310 () | 13375..13758 | - | 384 | Protein_15 | IS3 family transposase IS629 | Transposase |
| HR075_RS24315 () | 13848..15356 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| HR075_RS24320 () | 16029..16768 | - | 740 | Protein_17 | IS3 family transposase IS629 | Transposase |
| HR075_RS24325 () | 16870..17130 | + | 261 | WP_000371882.1 | hypothetical protein | - |
| HR075_RS24330 () | 17127..17636 | + | 510 | WP_000194542.1 | hypothetical protein | - |
| HR075_RS24335 () | 17656..18003 | - | 348 | WP_000142452.1 | hypothetical protein | - |
| HR075_RS24340 () | 18132..18467 | + | 336 | WP_001080732.1 | colicin transporter | - |
| HR075_RS24345 () | 19919..20605 | + | 687 | Protein_22 | replication initiation protein | - |
| HR075_RS24350 () | 20937..21812 | + | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| HR075_RS24355 () | 21820..22596 | + | 777 | WP_000981091.1 | energy transducer TonB | - |
| HR075_RS24360 () | 22765..25026 | + | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| HR075_RS24365 () | 25095..26270 | + | 1176 | WP_001020413.1 | putative protein YncE | VF |
| HR075_RS24370 () | 26793..27098 | - | 306 | Protein_27 | IS91 family transposase ISSbo1 | Transposase |
| HR075_RS24375 () | 27124..27863 | + | 740 | Protein_28 | IS3 family transposase IS629 | Transposase |
| HR075_RS24380 () | 28536..28850 | + | 315 | Protein_29 | IS5 family transposase ISKpn26 | Transposase |
| HR075_RS24385 () | 28851..29024 | + | 174 | Protein_30 | IS5 family transposase ISKpn26 | Transposase |
| HR075_RS24390 () | 29174..29807 | - | 634 | Protein_31 | histidine-type phosphatase | - |
| HR075_RS24395 () | 29929..30414 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| HR075_RS24400 () | 30439..30924 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| HR075_RS24405 () | 30911..31606 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| HR075_RS24410 () | 31611..32741 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| HR075_RS24415 () | 32731..34014 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| HR075_RS24420 () | 34017..35396 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| HR075_RS24425 () | 35500..36027 | - | 528 | WP_000178050.1 | iron transporter | - |
| HR075_RS24430 () | 36068..37954 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| HR075_RS24435 () | 38301..39116 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| HR075_RS24440 () | 39299..39805 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| HR075_RS24445 () | 39795..39953 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| HR075_RS24450 () | 40103..40807 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HR075_RS24455 () | 41106..41966 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HR075_RS24460 () | 42116..42214 | - | 99 | Protein_45 | IS1 family transposase | - |
| HR075_RS24465 () | 42243..43553 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| HR075_RS24470 () | 43838..44239 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HR075_RS24475 () | 44172..44429 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HR075_RS24480 () | 44522..45175 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HR075_RS24485 () | 46115..46972 | - | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| HR075_RS24490 () | 46965..47039 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| HR075_RS24495 () | 47276..47530 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| HR075_RS24500 () | 47827..47961 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 48006..48066 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 48006..48066 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 48006..48066 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 48006..48066 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| HR075_RS24505 () | 48033..48319 | - | 287 | Protein_54 | DUF2726 domain-containing protein | - |
| HR075_RS24510 () | 48397..50010 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| HR075_RS24515 () | 50041..50391 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| HR075_RS24520 () | 50388..50813 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| HR075_RS24525 () | 51372..51584 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| HR075_RS24530 () | 51715..52275 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| HR075_RS24535 () | 52330..53076 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| HR075_RS24540 () | 53096..58366 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| HR075_RS24545 () | 58366..60564 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| HR075_RS24550 () | 60561..61340 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| HR075_RS24555 () | 61543..62274 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| HR075_RS24560 () | 62306..62803 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| HR075_RS24565 () | 62822..65641 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HR075_RS24570 () | 65638..67010 | - | 1373 | Protein_67 | conjugal transfer protein TraH | - |
| HR075_RS24575 () | 66997..67422 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| HR075_RS24580 () | 67370..67717 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| HR075_RS24585 () | 67647..68192 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HR075_RS24590 () | 68179..68463 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HR075_RS24595 () | 68590..68910 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| HR075_RS24600 () | 68958..69655 | - | 698 | Protein_73 | IS1 family transposase IS1G | Transposase |
| HR075_RS24605 () | 69871..70614 | - | 744 | WP_001030401.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HR075_RS24610 () | 70607..70864 | - | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| HR075_RS24615 () | 70891..72741 | - | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HR075_RS24620 () | 72738..73376 | - | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HR075_RS24625 () | 73385..73690 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| HR075_RS24630 () | 73720..74712 | - | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| HR075_RS24635 () | 74709..75341 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| HR075_RS24640 () | 75338..75724 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| HR075_RS24645 () | 75721..78348 | - | 2628 | WP_001064258.1 | type IV secretion system protein TraC | - |
| HR075_RS24650 () | 78508..78729 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| HR075_RS24655 () | 78864..79379 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HR075_RS24660 () | 79379..79738 | - | 360 | WP_001617876.1 | conjugal transfer protein TrbD | - |
| HR075_RS24665 () | 79677..80264 | - | 588 | WP_013023871.1 | conjugal transfer protein TraP | - |
| HR075_RS24670 () | 80233..81684 | - | 1452 | WP_000146687.1 | conjugal transfer protein TraB | - |
| HR075_RS24675 () | 81684..82388 | - | 705 | WP_148725207.1 | type-F conjugative transfer system secretin TraK | - |
| HR075_RS24680 () | 82399..82965 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| HR075_RS24685 () | 82987..83298 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| HR075_RS24690 () | 83303..83665 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| HR075_RS24695 () | 83699..83926 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| HR075_RS24700 () | 84014..84691 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| HR075_RS24705 () | 84825..85208 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| HR075_RS24710 () | 85539..86141 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| HR075_RS24715 () | 86438..87259 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| HR075_RS24720 () | 87378..87665 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HR075_RS24725 () | 87690..87896 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| HR075_RS24730 () | 87809..88144 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| HR075_RS24735 () | 88587..88745 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 88789..88829 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 88789..88829 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 88789..88829 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 88789..88829 | - | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 90273..90459 | - | 187 | NuclAT_0 | - | - |
| - () | 90273..90459 | - | 187 | NuclAT_0 | - | - |
| - () | 90273..90459 | - | 187 | NuclAT_0 | - | - |
| - () | 90273..90459 | - | 187 | NuclAT_0 | - | - |
| HR075_RS24745 () | 90471..91190 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| HR075_RS24750 () | 91187..91621 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| HR075_RS24755 () | 91676..93634 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| HR075_RS24760 () | 93700..93933 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| HR075_RS24765 () | 93996..94535 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| HR075_RS24770 () | 94680..95015 | - | 336 | WP_013023883.1 | hypothetical protein | - |
| HR075_RS24775 () | 95178..95396 | - | 219 | WP_001496291.1 | hypothetical protein | - |
| HR075_RS24780 () | 95422..95985 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| HR075_RS24785 () | 96033..97394 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| HR075_RS24790 () | 97446..97676 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| HR075_RS24795 () | 98711..98902 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| HR075_RS24800 () | 98899..99321 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HR075_RS24805 () | 99368..99670 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| HR075_RS24810 () | 100210..100986 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| HR075_RS24815 () | 101037..101471 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| HR075_RS24820 () | 101485..101706 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| HR075_RS24825 () | 101707..102390 | - | 684 | WP_000086185.1 | DNA methylase | - |
| HR075_RS24830 () | 102467..102771 | - | 305 | Protein_119 | hypothetical protein | - |
| HR075_RS24835 () | 102775..103677 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HR075_RS24840 () | 104544..105515 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HR075_RS24845 () | 105515..106681 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| HR075_RS24850 () | 107269..108024 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| HR075_RS24855 () | 108798..109604 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| HR075_RS24860 () | 109605..109910 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| HR075_RS24865 () | 109912..110130 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| HR075_RS24870 () | 110838..111833 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| HR075_RS24875 () | 111837..112769 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| HR075_RS24880 () | 112906..113603 | - | 698 | Protein_129 | IS1 family transposase IS1G | Transposase |
| HR075_RS24885 () | 113817..116933 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| HR075_RS24890 () | 117055..118326 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| HR075_RS24895 () | 118323..119879 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| HR075_RS24900 () | 120062..120283 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HR075_RS24905 () | 120283..120663 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| HR075_RS24910 () | 120668..120847 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| HR075_RS24915 () | 120875..121234 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| HR075_RS24920 () | 121158..121571 | + | 414 | Protein_137 | IS3 family transposase ISLad1 | Transposase |
| HR075_RS24925 () | 121521..121838 | - | 318 | WP_001513659.1 | hypothetical protein | - |
| HR075_RS24930 () | 122066..123082 | - | 1017 | WP_012372828.1 | IS5 family transposase IS5D | Transposase |
| HR075_RS24935 () | 123290..124693 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| HR075_RS24940 () | 124680..125612 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| HR075_RS24945 () | 125721..126050 | - | 330 | Protein_142 | TOBE domain-containing protein | - |
| HR075_RS24950 () | 126066..126763 | - | 698 | Protein_143 | IS1 family transposase IS1R | Transposase |
| HR075_RS24955 () | 126821..127069 | + | 249 | Protein_144 | abortive infection family protein | - |
| HR075_RS24960 () | 127438..128169 | - | 732 | WP_001617898.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|