MGE detailed information
MGE type: Conjugative plasmid MGE length: 119964 bp
Accession: NZ_CP053298 Location: 1..119964 Organism: Escherichia coli strain M1/5 Replicon: plasmid pM1-5_120
Accession: NZ_CP053298 Location: 1..119964 Organism: Escherichia coli strain M1/5 Replicon: plasmid pM1-5_120
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HLK60_RS25020 () | 1012..1709 | - | 698 | Protein_1 | IS1 family transposase IS1A | Transposase |
| HLK60_RS25025 () | 1939..4140 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| HLK60_RS25030 () | 4222..5499 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| HLK60_RS25035 () | 5496..7238 | - | 1743 | WP_021517443.1 | Aerobactin synthase | VF |
| HLK60_RS25040 () | 7238..8185 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| HLK60_RS25045 () | 8186..9910 | - | 1725 | WP_178318167.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| HLK60_RS25050 () | 10046..11239 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| HLK60_RS25055 () | 11556..12718 | + | 1163 | WP_085947771.1 | IS3 family transposase IS3 | Transposase |
| HLK60_RS25060 () | 12880..13260 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| HLK60_RS25065 () | 13601..13768 | - | 168 | Protein_10 | phosphopyruvate hydratase | - |
| HLK60_RS25070 () | 13808..14623 | - | 816 | Protein_11 | IS3 family transposase IS629 | Transposase |
| HLK60_RS25075 () | 14648..15427 | - | 780 | WP_021556352.1 | IS21 family transposase IS100kyp | Transposase |
| HLK60_RS25080 () | 15427..16449 | - | 1023 | WP_000255944.1 | IS21 family transposase IS100kyp | Transposase |
| HLK60_RS25085 () | 16463..16657 | - | 195 | WP_171004018.1 | IS3 family transposase IS629 | Transposase |
| HLK60_RS25090 () | 16654..16980 | - | 327 | WP_000165261.1 | IS3 family transposase IS629 | Transposase |
| HLK60_RS25095 () | 17031..17345 | - | 315 | Protein_16 | universal stress protein | - |
| HLK60_RS25100 () | 17349..18251 | - | 903 | WP_000640873.1 | manganese-dependent inorganic pyrophosphatase | - |
| HLK60_RS25105 () | 18532..18855 | - | 324 | WP_001553721.1 | Tn3 family transposase ISEc63 | Transposase |
| HLK60_RS25110 () | 18826..20531 | + | 1706 | Protein_19 | Tn3 family transposase | - |
| HLK60_RS25115 () | 20765..21622 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| HLK60_RS25120 () | 21619..22476 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| HLK60_RS25125 () | 22473..23300 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| HLK60_RS25130 () | 23300..24214 | - | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| HLK60_RS25135 () | 24570..25267 | + | 698 | Protein_24 | IS1 family transposase IS1A | Transposase |
| HLK60_RS25140 () | 25448..25961 | - | 514 | Protein_25 | DUF4113 domain-containing protein | - |
| HLK60_RS25145 () | 26022..26126 | - | 105 | Protein_26 | AAA family ATPase | - |
| HLK60_RS25150 () | 26128..26451 | - | 324 | Protein_27 | IS21 family transposase IS21 | Transposase |
| HLK60_RS25155 () | 27197..28174 | + | 978 | WP_021517434.1 | RepB family plasmid replication initiator protein | - |
| HLK60_RS25160 () | 28453..29193 | - | 741 | WP_021517433.1 | IS91 family transposase ISMno23 | Transposase |
| HLK60_RS25165 () | 29212..29909 | - | 698 | Protein_30 | IS1 family transposase IS1S | Transposase |
| HLK60_RS25170 () | 29967..30821 | + | 855 | Protein_31 | ABC transporter permease | - |
| HLK60_RS25175 () | 30811..31941 | + | 1131 | WP_000729219.1 | ABC transporter permease | - |
| HLK60_RS25180 () | 31946..32641 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| HLK60_RS25185 () | 32628..33113 | + | 486 | WP_001554949.1 | TlpA family protein disulfide reductase | - |
| HLK60_RS25190 () | 33138..33623 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| HLK60_RS25195 () | 33745..34377 | + | 633 | Protein_36 | histidine-type phosphatase | - |
| HLK60_RS25200 () | 34527..35506 | - | 980 | Protein_37 | IS5 family transposase ISKpn26 | Transposase |
| HLK60_RS25205 () | 35608..36120 | + | 513 | WP_021517418.1 | Serine protease EspC | VF |
| HLK60_RS25215 () | 37362..37667 | + | 306 | Protein_40 | IS91 family transposase ISSbo1 | Transposase |
| HLK60_RS25220 () | 38187..38687 | - | 501 | Protein_41 | putative protein YncE | VF |
| HLK60_RS25225 () | 38745..39442 | + | 698 | Protein_42 | IS1 family transposase | - |
| HLK60_RS25230 () | 39505..39780 | - | 276 | WP_021517414.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HLK60_RS25235 () | 39780..40064 | - | 285 | WP_001178089.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| HLK60_RS25240 () | 40969..41826 | - | 858 | WP_021517415.1 | incFII family plasmid replication initiator RepA | - |
| HLK60_RS25245 () | 41819..41893 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| HLK60_RS25250 () | 42129..42386 | - | 258 | WP_000083826.1 | replication regulatory protein RepA | - |
| HLK60_RS25255 () | 42626..43216 | - | 591 | WP_000766805.1 | DUF2726 domain-containing protein | - |
| HLK60_RS25260 () | 43255..43464 | - | 210 | WP_001309247.1 | hemolysin expression modulator Hha | - |
| HLK60_RS25265 () | 43510..43971 | - | 462 | WP_001233842.1 | thermonuclease family protein | - |
| HLK60_RS25270 () | 44216..44428 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| HLK60_RS25275 () | 44557..45117 | - | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| HLK60_RS25280 () | 45220..46080 | - | 861 | WP_000704523.1 | putative protein YcjY | VF |
| HLK60_RS25285 () | 46139..46648 | - | 510 | Protein_54 | type-F conjugative transfer system pilin acetylase TraX | - |
| HLK60_RS25290 () | 46704..47917 | + | 1214 | WP_164965821.1 | IS3 family transposase IS629 | Transposase |
| HLK60_RS25295 () | 48393..49865 | - | 1473 | WP_000621194.1 | sensor histidine kinase | - |
| HLK60_RS25300 () | 49862..50584 | - | 723 | WP_001057737.1 | Transcriptional regulatory protein WalR | VF |
| HLK60_RS25305 () | 50726..51325 | + | 600 | WP_001177183.1 | cytochrome b/b6 domain-containing protein | - |
| HLK60_RS25310 () | 51336..52106 | + | 771 | WP_000712166.1 | molybdopterin-dependent oxidoreductase | - |
| HLK60_RS25315 () | 52136..52375 | + | 240 | WP_001554944.1 | hypothetical protein | - |
| HLK60_RS25320 () | 52528..52629 | - | 102 | Protein_61 | transposase | - |
| HLK60_RS25325 () | 52711..53115 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| HLK60_RS25330 () | 53112..53459 | + | 348 | WP_021517412.1 | IS66 family transposase ISKpn24 | Transposase |
| HLK60_RS25335 () | 53508..55046 | + | 1539 | WP_021517411.1 | IS66 family transposase ISEc22 | Transposase |
| HLK60_RS25340 () | 55109..55900 | - | 792 | WP_021517410.1 | DUF4198 domain-containing protein | - |
| HLK60_RS25345 () | 55907..57877 | - | 1971 | WP_021517409.1 | Hemin receptor | VF |
| HLK60_RS25350 () | 58159..58595 | + | 437 | Protein_67 | IS3 family transposase IS2 | Transposase |
| HLK60_RS25355 () | 59120..59392 | + | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| HLK60_RS25360 () | 59838..60013 | + | 176 | Protein_69 | IS3 family transposase | - |
| HLK60_RS25365 () | 60239..61408 | - | 1170 | WP_001072359.1 | hypothetical protein | - |
| HLK60_RS25370 () | 61775..61963 | + | 189 | WP_023150877.1 | hypothetical protein | - |
| HLK60_RS25375 () | 62145..62842 | + | 698 | Protein_72 | IS1 family transposase IS1S | Transposase |
| HLK60_RS25380 () | 63383..63718 | - | 336 | WP_001080732.1 | colicin transporter | - |
| HLK60_RS25385 () | 63847..64194 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| HLK60_RS25390 () | 64214..64804 | - | 591 | WP_021517407.1 | hypothetical protein | - |
| HLK60_RS25395 () | 64801..65061 | - | 261 | WP_021517406.1 | hypothetical protein | - |
| HLK60_RS25400 () | 65160..66373 | + | 1214 | WP_171004019.1 | IS3 family transposase IS629 | Transposase |
| HLK60_RS25405 () | 66773..67978 | + | 1206 | WP_001442122.1 | Plasmid partition protein A | VF |
| HLK60_RS25410 () | 67975..68946 | + | 972 | WP_001233385.1 | ParB/RepB/Spo0J family partition protein | - |
| HLK60_RS25415 () | 69083..70228 | - | 1146 | Protein_80 | translesion error-prone DNA polymerase V subunit UmuC | - |
| HLK60_RS25420 () | 70291..71289 | + | 999 | Protein_81 | IS91 family transposase ISMno24 | Transposase |
| HLK60_RS25425 () | 71286..72197 | + | 912 | WP_021517403.1 | hypothetical protein | - |
| HLK60_RS25430 () | 72274..73395 | + | 1122 | Protein_83 | tyrosine-type recombinase/integrase | - |
| HLK60_RS25435 () | 73407..74104 | - | 698 | Protein_84 | IS1 family transposase IS1A | Transposase |
| HLK60_RS25440 () | 74756..75253 | + | 498 | WP_050575716.1 | single-stranded DNA-binding protein | - |
| HLK60_RS25445 () | 75316..75549 | + | 234 | WP_021517399.1 | DUF905 domain-containing protein | - |
| HLK60_RS25450 () | 75608..77566 | + | 1959 | WP_021517398.1 | ParB/RepB/Spo0J family partition protein | - |
| HLK60_RS25455 () | 77621..78055 | + | 435 | WP_021517397.1 | conjugation system SOS inhibitor PsiB | - |
| HLK60_RS25460 () | 78052..78771 | + | 720 | Protein_89 | plasmid SOS inhibition protein A | - |
| - () | 78782..78993 | + | 212 | NuclAT_0 | - | - |
| - () | 78782..78993 | + | 212 | NuclAT_0 | - | - |
| - () | 78782..78993 | + | 212 | NuclAT_0 | - | - |
| - () | 78782..78993 | + | 212 | NuclAT_0 | - | - |
| HLK60_RS25465 () | 79046..79207 | + | 162 | WP_001332444.1 | type I toxin-antitoxin system Hok family toxin | - |
| HLK60_RS25470 () | 79445..79762 | - | 318 | WP_001775930.1 | hypothetical protein | - |
| HLK60_RS25475 () | 79830..80126 | + | 297 | WP_021517395.1 | hypothetical protein | - |
| HLK60_RS25480 () | 80237..81058 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| HLK60_RS25485 () | 81355..81957 | - | 603 | WP_077764608.1 | hypothetical protein | VF |
| HLK60_RS25490 () | 82280..82663 | + | 384 | WP_021517393.1 | relaxosome protein TraM | - |
| HLK60_RS25495 () | 82854..83507 | + | 654 | WP_021517392.1 | hypothetical protein | - |
| HLK60_RS25500 () | 83632..83859 | + | 228 | WP_000089265.1 | conjugal transfer relaxosome protein TraY | - |
| HLK60_RS25505 () | 83892..84254 | + | 363 | WP_021517391.1 | type IV conjugative transfer system pilin TraA | - |
| HLK60_RS25510 () | 84269..84580 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| HLK60_RS25515 () | 84602..85168 | + | 567 | WP_000399801.1 | type IV conjugative transfer system protein TraE | - |
| HLK60_RS25520 () | 85155..85883 | + | 729 | WP_021517390.1 | type-F conjugative transfer system secretin TraK | - |
| HLK60_RS25525 () | 85883..87310 | + | 1428 | WP_021517389.1 | conjugal transfer protein TraB | - |
| HLK60_RS25530 () | 87300..87890 | + | 591 | WP_000002784.1 | conjugal transfer protein TraP | - |
| HLK60_RS25535 () | 87829..88197 | + | 369 | WP_021517388.1 | conjugal transfer protein TrbD | - |
| HLK60_RS25540 () | 88194..88709 | + | 516 | WP_001681800.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HLK60_RS25545 () | 88844..89065 | + | 222 | WP_024189400.1 | conjugal transfer protein TraR | - |
| HLK60_RS25550 () | 89058..89471 | + | 414 | WP_000549574.1 | hypothetical protein | - |
| HLK60_RS25555 () | 89464..89937 | + | 474 | WP_021517387.1 | hypothetical protein | - |
| HLK60_RS25560 () | 90017..90259 | + | 243 | WP_021517386.1 | hypothetical protein | - |
| HLK60_RS25565 () | 90261..90623 | + | 363 | WP_021517385.1 | hypothetical protein | - |
| HLK60_RS25570 () | 90749..93055 | + | 2307 | WP_021517384.1 | type IV secretion system protein TraC | - |
| HLK60_RS25575 () | 93085..93390 | + | 306 | WP_021517383.1 | hypothetical protein | - |
| HLK60_RS25580 () | 93399..94037 | + | 639 | WP_021517382.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HLK60_RS25585 () | 94034..94405 | + | 372 | WP_021517381.1 | hypothetical protein | - |
| HLK60_RS25590 () | 94430..94852 | + | 423 | WP_021517380.1 | HNH endonuclease | - |
| HLK60_RS25595 () | 94849..96699 | + | 1851 | WP_021517379.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HLK60_RS25600 () | 96726..96983 | + | 258 | WP_000864314.1 | conjugal transfer protein TrbE | - |
| HLK60_RS25605 () | 96976..97719 | + | 744 | WP_021517378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HLK60_RS25610 () | 97733..98074 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| HLK60_RS25615 () | 98055..98390 | - | 336 | WP_000736414.1 | hypothetical protein | - |
| HLK60_RS25620 () | 98471..98755 | + | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HLK60_RS25625 () | 98742..99287 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HLK60_RS25630 () | 99217..99565 | + | 349 | Protein_123 | P-type conjugative transfer protein TrbJ | - |
| HLK60_RS25635 () | 99513..99938 | + | 426 | WP_071781062.1 | F-type conjugal transfer protein TrbF | - |
| HLK60_RS25640 () | 99925..101298 | + | 1374 | WP_001673176.1 | conjugal transfer protein TraH | - |
| HLK60_RS25645 () | 101295..104117 | + | 2823 | WP_021517376.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HLK60_RS25650 () | 104132..104635 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| HLK60_RS25655 () | 104667..105398 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| HLK60_RS25660 () | 105601..106380 | + | 780 | WP_021517375.1 | hypothetical protein | - |
| HLK60_RS25665 () | 106377..108548 | + | 2172 | WP_178318168.1 | type IV conjugative transfer system coupling protein TraD | - |
| HLK60_RS25670 () | 108548..113818 | + | 5271 | WP_021517373.1 | Multifunctional conjugation protein TraI | Relaxase |
| HLK60_RS25675 () | 113838..114077 | + | 240 | Protein_132 | conjugal transfer protein | - |
| HLK60_RS25685 () | 115472..116278 | - | 807 | WP_021517370.1 | site-specific integrase | - |
| HLK60_RS25690 () | 116279..116584 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| HLK60_RS25695 () | 116586..116804 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| HLK60_RS25700 () | 117432..117662 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| HLK60_RS25705 () | 117659..118075 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | - |
| HLK60_RS25710 () | 118150..119715 | + | 1566 | WP_021517369.1 | AAA family ATPase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|