MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 186278 bp
Accession: NZ_CP050827 Location: 1..186278 Organism: Klebsiella pneumoniae strain Bckp212 Replicon: plasmid pBckp212-1
Accession: NZ_CP050827 Location: 1..186278 Organism: Klebsiella pneumoniae strain Bckp212 Replicon: plasmid pBckp212-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HC649_RS25860 () | 1..1539 | + | 1539 | WP_101979470.1 | IS66 family transposase ISKpn24 | Transposase |
| HC649_RS25865 () | 1591..2529 | - | 939 | WP_023287225.1 | LysR family transcriptional regulator | - |
| HC649_RS25870 () | 2562..3476 | - | 915 | WP_023287224.1 | alpha/beta hydrolase | - |
| HC649_RS25875 () | 3487..4356 | - | 870 | WP_023287223.1 | fumarylacetoacetate hydrolase family protein | - |
| HC649_RS25880 () | 4373..4996 | - | 624 | WP_023287222.1 | 3-isopropylmalate dehydratase small subunit | - |
| HC649_RS25885 () | 4983..6419 | - | 1437 | WP_167813114.1 | 3-isopropylmalate dehydratase large subunit | - |
| HC649_RS25890 () | 6549..7781 | - | 1233 | WP_023288221.1 | MFS transporter | - |
| HC649_RS25895 () | 8291..9259 | + | 969 | WP_100112216.1 | IS5 family transposase IS903 | Transposase |
| HC649_RS25900 () | 9340..10417 | - | 1078 | Protein_8 | FUSC family protein | - |
| HC649_RS25905 () | 10537..10890 | - | 354 | WP_017146595.1 | hypothetical protein | - |
| HC649_RS25910 () | 10883..11083 | - | 201 | WP_024193481.1 | hypothetical protein | - |
| HC649_RS25915 () | 11623..12141 | - | 519 | Protein_11 | Methyl-accepting chemotaxis protein II | VF |
| HC649_RS25920 () | 12212..13099 | + | 888 | Protein_12 | IS5 family transposase ISKpn26 | Transposase |
| HC649_RS25925 () | 13132..14100 | + | 969 | WP_167813116.1 | IS5 family transposase IS903B | Transposase |
| HC649_RS25935 () | 14306..14608 | - | 303 | WP_167813119.1 | hypothetical protein | - |
| HC649_RS25940 () | 14678..15097 | - | 420 | WP_011251286.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| HC649_RS25945 () | 15094..15405 | - | 312 | WP_011251285.1 | type II toxin-antitoxin system HigB family toxin | Toxin Detail |
| HC649_RS25950 () | 15610..16068 | - | 459 | Protein_17 | IS3 family transposase ISEc27 | Transposase |
| HC649_RS25955 () | 16161..16499 | + | 339 | WP_023288266.1 | IS66 family transposase ISSgsp1 | Transposase |
| HC649_RS25960 () | 16496..16843 | + | 348 | WP_032430752.1 | IS66 family transposase ISCfr14 | Transposase |
| HC649_RS25965 () | 16892..18430 | + | 1539 | WP_032430751.1 | IS66 family transposase ISEc22 | Transposase |
| HC649_RS25970 () | 18470..18649 | + | 180 | Protein_21 | IS5 family transposase IS903B | Transposase |
| HC649_RS25975 () | 19195..20175 | - | 981 | WP_048293850.1 | IS5 family transposase ISKpn26 | Transposase |
| HC649_RS25980 () | 20374..21741 | - | 1368 | WP_101979500.1 | formimidoylglutamate deiminase | - |
| HC649_RS25985 () | 21844..22605 | + | 762 | WP_017900871.1 | histidine utilization repressor | - |
| HC649_RS25990 () | 22602..23159 | + | 558 | WP_017900872.1 | HutD family protein | - |
| HC649_RS25995 () | 23193..24725 | - | 1533 | WP_032430756.1 | aromatic amino acid ammonia-lyase | - |
| HC649_RS26000 () | 24736..25611 | - | 876 | WP_017900874.1 | ABC transporter substrate-binding protein | - |
| HC649_RS26005 () | 25642..26322 | - | 681 | WP_014228066.1 | ABC transporter permease | - |
| HC649_RS26010 () | 26325..26969 | - | 645 | WP_032430757.1 | ABC transporter permease subunit | - |
| HC649_RS26015 () | 26966..28063 | - | 1098 | WP_167813121.1 | Osmoprotectant import ATP-binding protein OsmV | VF |
| HC649_RS26020 () | 28580..29339 | + | 760 | Protein_31 | hypothetical protein | - |
| HC649_RS26025 () | 29348..30256 | + | 909 | WP_160421093.1 | urocanate hydratase | - |
| HC649_RS26030 () | 30310..31704 | + | 1395 | WP_101979007.1 | cytosine permease | - |
| HC649_RS26035 () | 31716..32924 | + | 1209 | WP_101979008.1 | imidazolonepropionase | - |
| HC649_RS26040 () | 32917..33726 | + | 810 | WP_017900880.1 | N-formylglutamate deformylase | - |
| HC649_RS26045 () | 34467..34874 | + | 408 | WP_101979009.1 | IS66 family transposase ISCro1 | Transposase |
| HC649_RS26050 () | 34871..35107 | + | 237 | Protein_37 | IS66 family transposase IS682 | Transposase |
| HC649_RS26055 () | 35163..35588 | - | 426 | Protein_38 | IS5 family transposase ISPan1 | Transposase |
| HC649_RS26060 () | 35620..35955 | - | 336 | Protein_39 | conjugal transfer protein TraI | - |
| HC649_RS26065 () | 35969..36757 | - | 789 | WP_101979139.1 | hypothetical protein | - |
| HC649_RS26070 () | 36757..37221 | - | 465 | WP_048291880.1 | hypothetical protein | - |
| HC649_RS26075 () | 37909..38877 | + | 969 | WP_100112216.1 | IS5 family transposase IS903 | Transposase |
| HC649_RS26930 () | 38874..39638 | + | 765 | Protein_43 | hypothetical protein | - |
| HC649_RS26085 () | 39831..40355 | + | 525 | WP_071444207.1 | hypothetical protein | - |
| HC649_RS26090 () | 40553..41251 | + | 699 | Protein_45 | IS1 family transposase IS1G | Transposase |
| HC649_RS26095 () | 41275..42078 | - | 804 | WP_101979506.1 | hypothetical protein | - |
| HC649_RS26100 () | 42202..43485 | - | 1284 | WP_101978909.1 | ISNCY family transposase ISLad2 | Transposase |
| HC649_RS26105 () | 43724..44083 | + | 360 | Protein_48 | LysR family transcriptional regulator | - |
| HC649_RS26110 () | 44245..45681 | - | 1437 | WP_048298736.1 | PLP-dependent aminotransferase family protein | - |
| HC649_RS26115 () | 45780..46568 | + | 789 | WP_023288270.1 | arylamine N-acetyltransferase | - |
| HC649_RS26120 () | 46910..47492 | + | 583 | Protein_51 | IS110 family transposase IS1618 | Transposase |
| HC649_RS26125 () | 47478..47678 | + | 201 | Protein_52 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HC649_RS26130 () | 47856..49388 | + | 1533 | Protein_53 | IS3 family transposase ISKpn38 | Transposase |
| HC649_RS26135 () | 49656..50624 | - | 969 | WP_023279773.1 | IS5 family transposase IS903B | Transposase |
| HC649_RS26140 () | 50720..53836 | - | 3117 | WP_080876680.1 | HsdR family type I site-specific deoxyribonuclease | - |
| HC649_RS26145 () | 53953..55194 | - | 1242 | WP_080876679.1 | restriction endonuclease subunit S | - |
| HC649_RS26150 () | 55191..56747 | - | 1557 | WP_080876678.1 | type I restriction-modification system subunit M | - |
| HC649_RS26155 () | 56951..58816 | - | 1866 | WP_080876690.1 | DUF262 domain-containing protein | - |
| HC649_RS26160 () | 59903..60097 | - | 195 | Protein_59 | transposase | - |
| HC649_RS26165 () | 61117..61233 | + | 117 | Protein_60 | transposase | - |
| HC649_RS26170 () | 61358..61528 | - | 171 | Protein_61 | LysR family transcriptional regulator | - |
| HC649_RS26175 () | 61653..61766 | + | 114 | WP_077252861.1 | IS3 family transposase | - |
| HC649_RS26180 () | 61858..63456 | - | 1599 | WP_101979531.1 | sensor domain-containing diguanylate cyclase | - |
| HC649_RS26190 () | 63827..64387 | - | 561 | Protein_64 | transposase | - |
| HC649_RS26195 () | 64422..65389 | - | 968 | Protein_65 | IS5 family transposase IS903B | Transposase |
| HC649_RS26200 () | 65422..66384 | + | 963 | Protein_66 | kinase | - |
| HC649_RS26205 () | 66763..67245 | + | 483 | WP_025999313.1 | hypothetical protein | - |
| HC649_RS26210 () | 67521..67925 | - | 405 | WP_004118061.1 | DUF2251 domain-containing protein | - |
| HC649_RS26215 () | 69074..70165 | + | 1092 | WP_127472195.1 | DNA-binding transcriptional repressor LacI | - |
| HC649_RS26220 () | 70273..73332 | + | 3060 | WP_167813123.1 | beta-galactosidase | - |
| HC649_RS26225 () | 73384..74637 | + | 1254 | WP_143832796.1 | lactose permease | - |
| HC649_RS26230 () | 74703..74843 | + | 141 | Protein_72 | galactoside O-acetyltransferase | - |
| HC649_RS26235 () | 74858..75372 | - | 515 | Protein_73 | IS1 family transposase IS1A | Transposase |
| HC649_RS26240 () | 75406..78291 | - | 2886 | WP_001138082.1 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| HC649_RS26245 () | 78417..79031 | + | 615 | WP_000904906.1 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| HC649_RS26250 () | 79096..80225 | + | 1130 | WP_167813125.1 | IS3 family transposase IS1133 | Transposase |
| HC649_RS26255 () | 80332..81135 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HC649_RS26260 () | 81135..81971 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| HC649_RS26270 () | 82080..82262 | - | 183 | Protein_79 | IS1 family transposase | - |
| HC649_RS26275 () | 82451..82711 | - | 261 | WP_004118092.1 | DUF2534 family protein | - |
| HC649_RS26280 () | 82768..84831 | - | 2064 | WP_101979536.1 | TonB-dependent copper receptor | - |
| HC649_RS26285 () | 84914..85333 | - | 420 | WP_101979537.1 | DUF2946 domain-containing protein | - |
| HC649_RS26290 () | 85718..85996 | - | 279 | WP_032435790.1 | DUF1778 domain-containing protein | - |
| HC649_RS26295 () | 86090..86301 | - | 212 | Protein_84 | hypothetical protein | - |
| HC649_RS26300 () | 87277..87591 | + | 315 | WP_042919293.1 | hypothetical protein | - |
| HC649_RS26305 () | 87834..88316 | - | 483 | WP_206040922.1 | hypothetical protein | - |
| HC649_RS26310 () | 89544..90428 | + | 885 | WP_004186900.1 | hypothetical protein | - |
| HC649_RS26315 () | 91325..92392 | - | 1068 | WP_016946353.1 | hypothetical protein | - |
| HC649_RS26320 () | 92478..92732 | - | 255 | WP_004186931.1 | hypothetical protein | - |
| HC649_RS26325 () | 92909..94045 | + | 1137 | WP_004186933.1 | tyrosine-type recombinase/integrase | - |
| HC649_RS26330 () | 94111..94428 | - | 318 | WP_004026552.1 | hypothetical protein | - |
| HC649_RS26335 () | 94580..94903 | - | 324 | WP_167813127.1 | hypothetical protein | - |
| HC649_RS26340 () | 94900..95658 | - | 759 | WP_004181760.1 | hypothetical protein | - |
| HC649_RS26345 () | 95655..96614 | - | 960 | WP_014386528.1 | hypothetical protein | - |
| HC649_RS26350 () | 96657..97064 | - | 408 | WP_004186937.1 | hypothetical protein | - |
| HC649_RS26355 () | 97074..97538 | - | 465 | WP_004181762.1 | hypothetical protein | - |
| HC649_RS26360 () | 97586..97828 | - | 243 | WP_004181763.1 | hypothetical protein | - |
| HC649_RS26365 () | 97815..98171 | - | 357 | Protein_98 | hypothetical protein | - |
| HC649_RS26370 () | 98242..99100 | + | 859 | Protein_99 | IS3 family transposase | - |
| HC649_RS26375 () | 99382..100458 | + | 1077 | WP_045372268.1 | IS110 family transposase ISEc21 | Transposase |
| HC649_RS26380 () | 100475..100783 | + | 309 | Protein_101 | IS3 family transposase ISLad1 | Transposase |
| HC649_RS26385 () | 100793..101785 | + | 993 | Protein_102 | IS21 family transposase ISEc62 | Transposase |
| HC649_RS26390 () | 102261..102782 | + | 522 | WP_004118235.1 | putative RNA polymerase sigma factor FecI | VF |
| HC649_RS26395 () | 102779..103732 | + | 954 | WP_017146590.1 | fec operon regulator FecR | - |
| HC649_RS26400 () | 103819..106143 | + | 2325 | WP_023287171.1 | Fe(3+) dicitrate transport protein FecA | - |
| HC649_RS26405 () | 106188..107090 | + | 903 | WP_023287170.1 | Fe(3+) dicitrate ABC transporter substrate-binding protein FecB | - |
| HC649_RS26410 () | 107087..108085 | + | 999 | WP_023287169.1 | Fe(3+) dicitrate transport system permease protein FecC | VF |
| HC649_RS26415 () | 108082..109038 | + | 957 | WP_004118246.1 | Fe(3+) dicitrate transport system permease protein FecD | VF |
| HC649_RS26420 () | 109039..109806 | + | 768 | WP_004152282.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| HC649_RS26425 () | 109905..110198 | + | 294 | WP_023287168.1 | IS66 family transposase ISKpn24 | Transposase |
| HC649_RS26430 () | 110273..110500 | + | 228 | Protein_111 | IS66 family transposase | - |
| HC649_RS26435 () | 110529..110807 | - | 279 | WP_023287167.1 | EAL domain-containing protein | - |
| HC649_RS26440 () | 111100..112182 | + | 1083 | WP_024241646.1 | DNA-binding transcriptional repressor LacI | - |
| HC649_RS26445 () | 112290..115364 | + | 3075 | WP_023287164.1 | beta-galactosidase | - |
| HC649_RS26450 () | 115416..116669 | + | 1254 | WP_023287163.1 | lactose permease | - |
| HC649_RS26455 () | 116785..117753 | - | 969 | WP_077263568.1 | IS5 family transposase IS903B | Transposase |
| HC649_RS26460 () | 117733..118086 | + | 354 | WP_113707494.1 | hypothetical protein | - |
| HC649_RS26465 () | 118197..118733 | + | 537 | WP_023287162.1 | hypothetical protein | - |
| HC649_RS26470 () | 118742..119200 | + | 459 | WP_032414405.1 | type II toxin-antitoxin system YafO family toxin | - |
| HC649_RS26475 () | 119287..120255 | - | 969 | WP_100112172.1 | IS5 family transposase IS903B | Transposase |
| HC649_RS26480 () | 120934..122119 | + | 1186 | Protein_121 | IS3 family transposase ISYps8 | Transposase |
| HC649_RS26485 () | 122330..122866 | + | 537 | WP_032414401.1 | hypothetical protein | - |
| HC649_RS26490 () | 123004..123280 | - | 277 | Protein_123 | IS3 family transposase | - |
| HC649_RS26495 () | 123638..124351 | + | 714 | Protein_124 | tyrosine-type recombinase/integrase | - |
| HC649_RS26500 () | 125173..126183 | - | 1011 | WP_017900946.1 | RepB family plasmid replication initiator protein | - |
| HC649_RS26505 () | 126913..128079 | + | 1167 | WP_023287153.1 | Sporulation initiation inhibitor protein Soj | VF |
| HC649_RS26510 () | 128079..129050 | + | 972 | WP_023287152.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HC649_RS26515 () | 129901..130129 | - | 229 | Protein_128 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HC649_RS26520 () | 130208..130839 | - | 632 | Protein_129 | DUF4113 domain-containing protein | - |
| HC649_RS26525 () | 130976..131673 | + | 698 | Protein_130 | IS1 family transposase IS1G | Transposase |
| HC649_RS26530 () | 131689..132666 | - | 978 | Protein_131 | IS110 family transposase ISEc21 | Transposase |
| HC649_RS26535 () | 132948..133806 | - | 859 | Protein_132 | IS3 family transposase | - |
| HC649_RS26540 () | 135220..136439 | - | 1220 | Protein_133 | ISL3 family transposase ISCfr12 | Transposase |
| HC649_RS26545 () | 136547..136969 | + | 423 | WP_023287178.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HC649_RS26550 () | 136969..137088 | + | 120 | Protein_135 | Tyrosine recombinase XerD | VF |
| HC649_RS26555 () | 137155..138141 | + | 987 | WP_101977301.1 | Tyrosine recombinase XerD | VF |
| HC649_RS26560 () | 138138..139046 | + | 909 | Protein_137 | site-specific integrase | - |
| HC649_RS26565 () | 139125..140348 | + | 1224 | WP_048292268.1 | tyrosine-type recombinase/integrase | - |
| HC649_RS26570 () | 140441..140959 | - | 519 | WP_012541817.1 | hypothetical protein | - |
| HC649_RS26575 () | 140972..141826 | - | 855 | WP_012541818.1 | WYL domain-containing protein | - |
| HC649_RS26580 () | 141963..143144 | + | 1182 | WP_023287181.1 | hypothetical protein | - |
| HC649_RS26585 () | 143141..145369 | + | 2229 | WP_023287182.1 | Mov34/MPN/PAD-1 family protein | - |
| HC649_RS26590 () | 145416..146564 | + | 1149 | Protein_143 | translesion error-prone DNA polymerase V subunit UmuC | - |
| HC649_RS26595 () | 146665..147108 | + | 444 | WP_023287184.1 | DUF2384 domain-containing protein | Antitoxin Detail |
| HC649_RS26600 () | 147105..147575 | + | 471 | WP_004144067.1 | RES family NAD+ phosphorylase | Toxin Detail |
| HC649_RS26605 () | 147662..148630 | + | 969 | WP_000654811.1 | IS5 family transposase IS903B | Transposase |
| HC649_RS26610 () | 149271..150640 | + | 1370 | WP_085956500.1 | IS3 family transposase ISKpn8 | Transposase |
| HC649_RS26615 () | 150637..150918 | - | 282 | Protein_148 | IS481 family transposase | - |
| HC649_RS26620 () | 150909..151877 | + | 969 | WP_167813129.1 | IS5 family transposase IS903B | Transposase |
| HC649_RS26625 () | 152216..153427 | - | 1212 | WP_017901247.1 | M24 family metallopeptidase | - |
| HC649_RS26630 () | 153514..154467 | - | 954 | WP_020481021.1 | Glycine cleavage system transcriptional activator | VF |
| HC649_RS26635 () | 154624..155472 | + | 849 | WP_101984551.1 | transporter substrate-binding domain-containing protein | - |
| HC649_RS26640 () | 155496..156167 | + | 672 | WP_017901245.1 | amino acid ABC transporter permease | - |
| HC649_RS26645 () | 156164..156826 | + | 663 | WP_017901244.1 | amino acid ABC transporter permease | - |
| HC649_RS26650 () | 156831..157649 | + | 819 | WP_017901243.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| HC649_RS26655 () | 157646..158611 | + | 966 | WP_017901242.1 | DMT family transporter | - |
| HC649_RS26660 () | 159031..159845 | - | 815 | Protein_157 | IS110 family transposase ISSm1 | Transposase |
| HC649_RS26665 () | 160021..160326 | + | 306 | Protein_158 | DUF4102 domain-containing protein | - |
| HC649_RS26935 () | 160324..160485 | + | 162 | Protein_159 | hypothetical protein | - |
| HC649_RS26670 () | 160520..161488 | + | 969 | WP_167813130.1 | IS5 family transposase IS903B | Transposase |
| HC649_RS26675 () | 162181..163089 | + | 909 | WP_001372261.1 | HNH endonuclease | - |
| HC649_RS26680 () | 163477..163827 | - | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| HC649_RS26685 () | 163971..164402 | - | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| HC649_RS26690 () | 164653..166128 | - | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HC649_RS26695 () | 166121..166801 | - | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| HC649_RS26700 () | 166991..168376 | + | 1386 | WP_000475503.1 | Cation efflux system protein CusC | VF |
| HC649_RS26705 () | 168405..168758 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| HC649_RS26710 () | 168872..170164 | + | 1293 | WP_004098959.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HC649_RS26715 () | 170175..173321 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HC649_RS26720 () | 173408..173848 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| HC649_RS26725 () | 173975..176422 | + | 2448 | WP_004187133.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HC649_RS26730 () | 176463..176660 | + | 198 | WP_101984396.1 | DUF2933 domain-containing protein | - |
| HC649_RS26735 () | 176694..177431 | - | 738 | WP_000287501.1 | Murein DD-endopeptidase MepM | VF |
| HC649_RS26740 () | 177720..178169 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| HC649_RS26745 () | 178403..180220 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| HC649_RS26750 () | 180226..181116 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| HC649_RS26755 () | 181156..181536 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| HC649_RS26760 () | 181541..182470 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| HC649_RS26765 () | 182525..183205 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| HC649_RS26770 () | 183202..184602 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| HC649_RS26775 () | 184818..185252 | + | 435 | WP_016151366.1 | hypothetical protein | - |
| HC649_RS26780 () | 185482..185886 | + | 405 | WP_101979471.1 | IS66 family transposase ISKpn24 | Transposase |
| HC649_RS26785 () | 185883..186230 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|