MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 157903 bp
Accession: NZ_CP050823 Location: 1..157903 Organism: Klebsiella pneumoniae strain Bckp091 Replicon: plasmid pBckp091-1
Accession: NZ_CP050823 Location: 1..157903 Organism: Klebsiella pneumoniae strain Bckp091 Replicon: plasmid pBckp091-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HC645_RS25585 () | 40..969 | - | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| HC645_RS25590 () | 974..1354 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| HC645_RS25595 () | 1394..2284 | - | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| HC645_RS25600 () | 2290..4107 | - | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| HC645_RS25605 () | 4341..4790 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| HC645_RS25610 () | 5079..5816 | + | 738 | WP_000287501.1 | Murein DD-endopeptidase MepM | VF |
| HC645_RS25615 () | 5850..6047 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| HC645_RS25620 () | 6088..8535 | - | 2448 | WP_167803471.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HC645_RS25625 () | 8662..9102 | - | 441 | WP_009654300.1 | hypothetical protein | - |
| HC645_RS25630 () | 9189..12335 | - | 3147 | WP_042946271.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HC645_RS25635 () | 12346..13638 | - | 1293 | WP_042946269.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HC645_RS25640 () | 13752..14105 | - | 354 | WP_155006900.1 | cation efflux system protein CusF | - |
| HC645_RS25645 () | 14134..15519 | - | 1386 | WP_155006901.1 | Cation efflux system protein CusC | VF |
| HC645_RS25650 () | 15709..16389 | + | 681 | WP_000697968.1 | Transcriptional regulatory protein CusR | VF |
| HC645_RS25655 () | 16382..17857 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HC645_RS25660 () | 18108..18539 | + | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| HC645_RS25665 () | 18683..19033 | + | 351 | WP_032435702.1 | DUF305 domain-containing protein | - |
| HC645_RS25670 () | 19420..20328 | - | 909 | WP_001372261.1 | HNH endonuclease | - |
| HC645_RS25675 () | 20783..21751 | - | 969 | WP_016151359.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS25680 () | 22031..23005 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| HC645_RS25685 () | 23361..23711 | + | 351 | WP_004206664.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| HC645_RS25690 () | 23763..24125 | + | 363 | WP_004206665.1 | arsenite efflux transporter metallochaperone ArsD | - |
| HC645_RS25695 () | 24143..25894 | + | 1752 | WP_016151356.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| HC645_RS25700 () | 25942..27231 | + | 1290 | WP_155006902.1 | arsenite efflux transporter membrane subunit ArsB | - |
| HC645_RS25705 () | 27244..27669 | + | 426 | WP_007779002.1 | glutaredoxin-dependent arsenate reductase | - |
| HC645_RS25710 () | 27702..28130 | - | 429 | WP_004206671.1 | GNAT family N-acetyltransferase | - |
| HC645_RS25715 () | 28252..30003 | - | 1752 | WP_164494899.1 | Arsenical pump-driving ATPase | VF |
| HC645_RS25720 () | 30028..30390 | - | 363 | WP_016151353.1 | arsenic metallochaperone ArsD family protein | - |
| HC645_RS25725 () | 30466..31011 | - | 546 | WP_016151352.1 | sigma-70 family RNA polymerase sigma factor | - |
| HC645_RS25730 () | 31020..31733 | - | 714 | WP_016151351.1 | arsenical resistance protein ArsH | - |
| HC645_RS25735 () | 31730..32056 | - | 327 | WP_016151350.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| HC645_RS25740 () | 32388..32885 | + | 498 | WP_007871777.1 | GNAT family N-acetyltransferase | - |
| HC645_RS25745 () | 32935..33096 | - | 162 | Protein_32 | aquaporin | - |
| HC645_RS25750 () | 33153..34121 | - | 969 | WP_167803472.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS25755 () | 34275..35600 | + | 1326 | WP_007896426.1 | pyridine nucleotide-disulfide oxidoreductase | - |
| HC645_RS25760 () | 35778..36473 | + | 696 | Protein_35 | IS1 family transposase | - |
| HC645_RS25765 () | 36844..37365 | + | 522 | WP_016151347.1 | putative RNA polymerase sigma factor FecI | VF |
| HC645_RS25770 () | 37362..38315 | + | 954 | WP_004118237.1 | fec operon regulator FecR | - |
| HC645_RS25775 () | 38402..40726 | + | 2325 | WP_007898891.1 | Fe(3+) dicitrate transport protein FecA | - |
| HC645_RS25780 () | 40771..41673 | + | 903 | WP_004118241.1 | Fe(3+) dicitrate ABC transporter substrate-binding protein FecB | - |
| HC645_RS25785 () | 41670..42668 | + | 999 | WP_004118243.1 | Fe(3+) dicitrate transport system permease protein FecC | VF |
| HC645_RS25790 () | 42665..43621 | + | 957 | WP_004118246.1 | Fe(3+) dicitrate transport system permease protein FecD | VF |
| HC645_RS25795 () | 43622..44389 | + | 768 | WP_004152282.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| HC645_RS25800 () | 44488..44781 | + | 294 | WP_004118251.1 | IS66 family transposase ISKpn24 | Transposase |
| HC645_RS25805 () | 44856..45083 | + | 228 | Protein_44 | IS66 family transposase | - |
| HC645_RS25810 () | 45112..45390 | - | 279 | WP_007898884.1 | putative signaling protein | VF |
| HC645_RS25815 () | 45504..45929 | - | 426 | WP_007898882.1 | glutaredoxin-dependent arsenate reductase | - |
| HC645_RS25820 () | 45942..47231 | - | 1290 | WP_007898880.1 | arsenic transporter | - |
| HC645_RS25825 () | 47276..47596 | - | 321 | WP_004206577.1 | transcriptional regulator | - |
| HC645_RS25830 () | 47682..48380 | + | 699 | WP_016151343.1 | arsenical resistance protein ArsH | - |
| HC645_RS25835 () | 48509..48814 | - | 306 | WP_004206574.1 | PadR family transcriptional regulator | - |
| HC645_RS25840 () | 48825..50030 | - | 1206 | WP_004206572.1 | chromate efflux transporter | - |
| HC645_RS25845 () | 50206..50598 | - | 393 | Protein_52 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| HC645_RS25850 () | 50657..51625 | - | 969 | WP_016151359.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS25860 () | 51659..51850 | - | 192 | Protein_54 | Tn3 family transposase TnpR_ISYps3 | Transposase |
| HC645_RS25865 () | 52009..53736 | + | 1728 | Protein_55 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| HC645_RS25870 () | 54096..55088 | - | 993 | WP_032435706.1 | zinc-binding alcohol dehydrogenase family protein | - |
| HC645_RS25875 () | 55458..56539 | + | 1082 | Protein_57 | Lactose operon repressor | VF |
| HC645_RS25880 () | 56647..59706 | + | 3060 | WP_047683449.1 | beta-galactosidase | - |
| HC645_RS25885 () | 59758..61011 | + | 1254 | WP_167803473.1 | lactose permease | - |
| HC645_RS25890 () | 61077..61217 | + | 141 | Protein_60 | galactoside O-acetyltransferase | - |
| HC645_RS25895 () | 61232..61927 | - | 696 | Protein_61 | IS1 family transposase | - |
| HC645_RS25900 () | 61983..62165 | + | 183 | Protein_62 | transposase | - |
| HC645_RS25905 () | 62404..62730 | - | 327 | WP_032435793.1 | hypothetical protein | - |
| HC645_RS25910 () | 62811..63707 | - | 897 | WP_004118106.1 | helix-turn-helix domain-containing protein | - |
| HC645_RS25915 () | 63872..64948 | - | 1077 | WP_016151338.1 | dihydroorotase | - |
| HC645_RS25920 () | 64945..66201 | - | 1257 | WP_004118110.1 | N-carbamoyl-L-amino-acid hydrolase | VF |
| HC645_RS25925 () | 66238..67179 | - | 942 | WP_004118113.1 | dihydroorotate dehydrogenase | - |
| HC645_RS25930 () | 67172..68020 | - | 849 | WP_016151336.1 | hypothetical protein | - |
| HC645_RS25935 () | 68385..69641 | + | 1257 | WP_004118116.1 | MFS transporter | - |
| HC645_RS25940 () | 69854..71119 | + | 1266 | WP_004118118.1 | hypothetical protein | - |
| HC645_RS25945 () | 71488..72468 | + | 981 | WP_000019441.1 | IS5 family transposase ISKpn26 | Transposase |
| HC645_RS25950 () | 72526..72870 | + | 345 | WP_167803474.1 | copper resistance protein CopC | - |
| HC645_RS25955 () | 72967..73227 | - | 261 | WP_004118092.1 | DUF2534 family protein | - |
| HC645_RS25960 () | 73284..75347 | - | 2064 | WP_032435791.1 | TonB-dependent copper receptor | - |
| HC645_RS25965 () | 75430..75849 | - | 420 | WP_015065566.1 | DUF2946 domain-containing protein | - |
| HC645_RS25970 () | 76234..76512 | - | 279 | WP_032435790.1 | DUF1778 domain-containing protein | - |
| HC645_RS25975 () | 76606..76818 | - | 213 | WP_004181742.1 | hypothetical protein | - |
| HC645_RS25980 () | 77795..78109 | + | 315 | WP_032435789.1 | hypothetical protein | - |
| HC645_RS25990 () | 79417..79599 | - | 183 | Protein_80 | IS5 family transposase ISPan1 | Transposase |
| HC645_RS25995 () | 79601..80596 | - | 996 | WP_167803475.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS26000 () | 80629..81492 | - | 864 | Protein_82 | IS5 family transposase IS903B | Transposase |
| HC645_RS26005 () | 81579..82049 | - | 471 | WP_004144067.1 | RES family NAD+ phosphorylase | Toxin Detail |
| HC645_RS26010 () | 82046..82489 | - | 444 | WP_023287184.1 | DUF2384 domain-containing protein | Antitoxin Detail |
| HC645_RS26015 () | 82590..83738 | - | 1149 | Protein_85 | translesion error-prone DNA polymerase V subunit UmuC | - |
| HC645_RS26020 () | 83785..86013 | - | 2229 | WP_032430744.1 | Mov34/MPN/PAD-1 family protein | - |
| HC645_RS26025 () | 86010..87191 | - | 1182 | WP_023287181.1 | hypothetical protein | - |
| HC645_RS26030 () | 87328..88182 | + | 855 | WP_012541818.1 | WYL domain-containing protein | - |
| HC645_RS26035 () | 88195..88713 | + | 519 | WP_032435786.1 | hypothetical protein | - |
| HC645_RS26040 () | 89291..90373 | + | 1083 | WP_024241646.1 | DNA-binding transcriptional repressor LacI | - |
| HC645_RS26045 () | 90481..93540 | + | 3060 | WP_167803476.1 | beta-galactosidase | - |
| HC645_RS26050 () | 93592..94845 | + | 1254 | WP_167803473.1 | lactose permease | - |
| HC645_RS26055 () | 94911..95051 | + | 141 | Protein_93 | galactoside O-acetyltransferase | - |
| HC645_RS26060 () | 95066..95760 | - | 695 | Protein_94 | IS1 family transposase | - |
| HC645_RS26065 () | 96114..96377 | - | 264 | Protein_95 | aldehyde dehydrogenase family protein | - |
| HC645_RS26070 () | 96411..97379 | + | 969 | WP_080857297.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS26075 () | 97581..98117 | + | 537 | WP_023288364.1 | hypothetical protein | - |
| HC645_RS26080 () | 98255..98528 | - | 274 | Protein_98 | IS3 family transposase | - |
| HC645_RS26085 () | 98632..98775 | + | 144 | WP_049257067.1 | hypothetical protein | - |
| HC645_RS26090 () | 98878..99617 | + | 740 | Protein_100 | site-specific integrase | - |
| HC645_RS26095 () | 100439..101449 | - | 1011 | WP_017900946.1 | RepB family plasmid replication initiator protein | - |
| HC645_RS26100 () | 102179..103345 | + | 1167 | WP_023287153.1 | Sporulation initiation inhibitor protein Soj | VF |
| HC645_RS26105 () | 103345..104316 | + | 972 | WP_004117790.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HC645_RS26520 () | 104754..105002 | - | 249 | Protein_104 | hypothetical protein | - |
| HC645_RS26110 () | 104999..105227 | - | 229 | Protein_105 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HC645_RS26115 () | 105306..105600 | - | 295 | Protein_106 | DUF4113 domain-containing protein | - |
| HC645_RS26120 () | 105685..106125 | + | 441 | WP_032435629.1 | IS66 family transposase ISKox1 | Transposase |
| HC645_RS26125 () | 106122..106472 | + | 351 | WP_004189161.1 | IS66 family transposase ISKox1 | Transposase |
| HC645_RS26130 () | 106503..108095 | + | 1593 | WP_167803477.1 | IS66 family transposase ISKox1 | Transposase |
| HC645_RS26135 () | 108240..108518 | + | 279 | WP_159106072.1 | hypothetical protein | - |
| HC645_RS26140 () | 108540..109508 | + | 969 | WP_167803478.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS26145 () | 109563..109942 | - | 380 | Protein_112 | IS1 family transposase | - |
| HC645_RS26150 () | 109960..110169 | + | 210 | Protein_113 | IS3 family transposase IS2 | Transposase |
| HC645_RS26155 () | 110188..111156 | - | 969 | WP_004213807.1 | IS110 family transposase ISSm3 | Transposase |
| HC645_RS26160 () | 111324..112399 | + | 1076 | Protein_115 | IS3 family transposase ISEc27 | Transposase |
| HC645_RS26165 () | 112420..112863 | + | 444 | WP_020477096.1 | hypothetical protein | - |
| HC645_RS26170 () | 112873..113280 | + | 408 | WP_032435642.1 | hypothetical protein | - |
| HC645_RS26175 () | 113323..114282 | + | 960 | WP_032435645.1 | DNA replication protein | - |
| HC645_RS26180 () | 114279..115037 | + | 759 | WP_117055987.1 | hypothetical protein | - |
| HC645_RS26185 () | 115034..115357 | + | 324 | WP_004197568.1 | hypothetical protein | - |
| HC645_RS26190 () | 115508..115825 | + | 318 | WP_004026552.1 | hypothetical protein | - |
| HC645_RS26195 () | 115891..117027 | - | 1137 | WP_032435650.1 | tyrosine-type recombinase/integrase | - |
| HC645_RS26200 () | 117204..117458 | + | 255 | WP_016946352.1 | transcriptional regulator | - |
| HC645_RS26205 () | 117544..118605 | + | 1062 | WP_032435651.1 | hypothetical protein | - |
| HC645_RS26210 () | 118926..119825 | + | 900 | WP_004026560.1 | RepB family plasmid replication initiator protein | - |
| HC645_RS26215 () | 120661..121317 | + | 657 | WP_032435708.1 | hypothetical protein | - |
| HC645_RS26220 () | 123183..124118 | + | 936 | WP_004026564.1 | Coagulase/fibrinolysin | VF |
| HC645_RS26225 () | 124591..125073 | + | 483 | WP_175437602.1 | hypothetical protein | - |
| HC645_RS26230 () | 125339..126501 | + | 1163 | WP_088941748.1 | IS3 family transposase ISSty2 | Transposase |
| HC645_RS26235 () | 126660..127118 | + | 459 | Protein_130 | IS3 family transposase ISEc27 | Transposase |
| HC645_RS26240 () | 127323..127634 | + | 312 | WP_011251285.1 | type II toxin-antitoxin system HigB family toxin | Toxin Detail |
| HC645_RS26245 () | 127631..128050 | + | 420 | WP_011251286.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| HC645_RS26250 () | 128197..129163 | + | 967 | Protein_133 | IS5 family transposase ISPan1 | Transposase |
| HC645_RS26255 () | 129307..129993 | - | 687 | Protein_134 | hypothetical protein | - |
| HC645_RS26260 () | 129993..130457 | - | 465 | WP_117055985.1 | hypothetical protein | - |
| HC645_RS26525 () | 131051..131806 | + | 756 | Protein_136 | hypothetical protein | - |
| HC645_RS26270 () | 131999..132523 | + | 525 | WP_029497499.1 | hypothetical protein | - |
| HC645_RS26275 () | 132721..133405 | + | 685 | Protein_138 | IS1 family transposase | - |
| HC645_RS26280 () | 133429..134232 | - | 804 | WP_029497501.1 | hypothetical protein | - |
| HC645_RS26285 () | 134293..135639 | - | 1347 | WP_077254792.1 | ISNCY family transposase ISLad2 | Transposase |
| HC645_RS26290 () | 135854..136021 | - | 168 | Protein_141 | IS3 family transposase | - |
| HC645_RS26295 () | 136037..136497 | - | 461 | Protein_142 | IS5 family transposase IS903 | Transposase |
| HC645_RS26300 () | 136553..137317 | - | 765 | WP_004184534.1 | IS21 family transposase ISEc10 | Transposase |
| HC645_RS26305 () | 137314..138813 | - | 1500 | WP_004184532.1 | IS21 family transposase ISEc10 | Transposase |
| HC645_RS26310 () | 138907..139344 | - | 438 | Protein_145 | IS5 family transposase ISPan1 | Transposase |
| HC645_RS26315 () | 140318..140524 | - | 207 | Protein_146 | IS3 family transposase IS2 | Transposase |
| HC645_RS26320 () | 141297..142265 | - | 969 | WP_167803479.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS26325 () | 142287..143513 | - | 1227 | WP_029497449.1 | site-specific integrase | - |
| HC645_RS26330 () | 143689..144503 | + | 815 | Protein_149 | IS110 family transposase ISSm1 | Transposase |
| HC645_RS26335 () | 144923..145888 | - | 966 | WP_017901242.1 | DMT family transporter | - |
| HC645_RS26340 () | 145885..146703 | - | 819 | WP_017901243.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| HC645_RS26345 () | 146708..147370 | - | 663 | WP_017901244.1 | amino acid ABC transporter permease | - |
| HC645_RS26350 () | 147367..148038 | - | 672 | WP_017901245.1 | amino acid ABC transporter permease | - |
| HC645_RS26355 () | 148062..148910 | - | 849 | WP_004118155.1 | transporter substrate-binding domain-containing protein | - |
| HC645_RS26360 () | 149067..150020 | + | 954 | WP_020481021.1 | Glycine cleavage system transcriptional activator | VF |
| HC645_RS26365 () | 150107..151318 | + | 1212 | WP_017901247.1 | M24 family metallopeptidase | - |
| HC645_RS26370 () | 151560..152528 | - | 969 | WP_077256550.1 | IS5 family transposase IS903B | Transposase |
| HC645_RS26375 () | 152659..152991 | + | 333 | Protein_158 | transposase | - |
| HC645_RS26380 () | 152988..153338 | + | 351 | WP_016151369.1 | IS66 family transposase ISEcl6 | Transposase |
| HC645_RS26385 () | 153369..154961 | + | 1593 | Protein_160 | IS66 family transposase ISEcl6 | Transposase |
| HC645_RS26390 () | 155161..155595 | - | 435 | WP_016151366.1 | hypothetical protein | - |
| HC645_RS26395 () | 155811..157211 | - | 1401 | WP_002436614.1 | copper resistance membrane spanning protein PcoS | - |
| HC645_RS26400 () | 157208..157888 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|