MGE detailed information
MGE type: Conjugative plasmid MGE length: 161057 bp
Accession: NZ_CP049355 Location: 1..161057 Organism: Escherichia coli strain T28R Replicon: plasmid pT28R-2
Accession: NZ_CP049355 Location: 1..161057 Organism: Escherichia coli strain T28R Replicon: plasmid pT28R-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G7B60_RS23235 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| G7B60_RS23240 () | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| G7B60_RS23245 () | 2124..2312 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| G7B60_RS23250 () | 2686..3588 | - | 903 | WP_001312822.1 | antimicrobial resistance protein Mig-14 | - |
| G7B60_RS23255 () | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| G7B60_RS23260 () | 5199..6152 | - | 954 | WP_000280980.1 | omptin family outer membrane protease | - |
| G7B60_RS23270 () | 7425..7583 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| G7B60_RS23275 () | 7767..8506 | + | 740 | Protein_7 | IS3 family transposase | - |
| G7B60_RS23280 () | 9179..10687 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| G7B60_RS23285 () | 10777..11250 | + | 474 | Protein_9 | IS3 family transposase | - |
| G7B60_RS23290 () | 11398..11666 | - | 269 | Protein_10 | integrase core domain-containing protein | - |
| G7B60_RS23295 () | 11723..12420 | + | 698 | Protein_11 | IS1 family transposase | - |
| G7B60_RS23300 () | 12498..13887 | - | 1390 | Protein_12 | ISNCY family transposase | - |
| G7B60_RS23305 () | 14197..14346 | - | 150 | Protein_13 | IS3 family transposase | - |
| G7B60_RS23310 () | 14524..15717 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| G7B60_RS23315 () | 16940..18176 | - | 1237 | Protein_15 | IS3 family transposase | - |
| G7B60_RS23320 () | 18803..19096 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| G7B60_RS23325 () | 19154..19353 | - | 200 | Protein_17 | lysis protein | - |
| G7B60_RS23330 () | 19907..21008 | + | 1102 | Protein_18 | transposase | - |
| G7B60_RS23335 () | 22244..23359 | + | 1116 | WP_001318220.1 | salmochelin biosynthesis C-glycosyltransferase IroB | - |
| G7B60_RS23340 () | 23499..27158 | + | 3660 | WP_001111199.1 | salmochelin/enterobactin export ABC transporter IroC | - |
| G7B60_RS23345 () | 27262..28491 | + | 1230 | WP_000933675.1 | catecholate siderophore esterase IroD | - |
| G7B60_RS23350 () | 28576..29532 | + | 957 | WP_064055648.1 | catecholate siderophore esterase IroE | - |
| G7B60_RS23355 () | 29577..31754 | - | 2178 | WP_001222186.1 | siderophore salmochelin receptor IroN | - |
| G7B60_RS23360 () | 31989..32686 | + | 698 | Protein_24 | IS1 family transposase | - |
| G7B60_RS23365 () | 32697..32900 | - | 204 | WP_001259759.1 | colicin V family bacteriocin | - |
| G7B60_RS23370 () | 32878..33114 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| G7B60_RS23375 () | 33603..34300 | + | 698 | Protein_27 | IS1 family transposase | - |
| G7B60_RS23380 () | 34355..34636 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| G7B60_RS23385 () | 34809..34976 | + | 168 | Protein_29 | colicin-B | - |
| G7B60_RS23390 () | 34994..35521 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| G7B60_RS23395 () | 35765..36580 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| G7B60_RS23400 () | 36630..36983 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| G7B60_RS23405 () | 37161..37952 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| G7B60_RS23410 () | 37949..38638 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| G7B60_RS23415 () | 38682..39032 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| G7B60_RS23420 () | 39564..43385 | - | 3822 | WP_064055658.1 | hypothetical protein | - |
| G7B60_RS23425 () | 43629..43790 | + | 162 | WP_000251882.1 | hypothetical protein | - |
| G7B60_RS23430 () | 43808..44155 | - | 348 | WP_000142450.1 | hypothetical protein | - |
| G7B60_RS23435 () | 44457..44939 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| G7B60_RS23440 () | 45056..45904 | - | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| G7B60_RS23445 () | 45950..46231 | - | 282 | WP_000969990.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| G7B60_RS23450 () | 46228..46305 | - | 78 | Protein_42 | toxin-antitoxin system protein | - |
| G7B60_RS23455 () | 46338..47852 | - | 1515 | Protein_43 | Tn3-like element TnAs1 family transposase | - |
| G7B60_RS23460 () | 47918..48622 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| G7B60_RS23470 () | 48925..49800 | + | 876 | WP_001617865.1 | class A extended-spectrum beta-lactamase CTX-M-14 | - |
| G7B60_RS23475 () | 49835..50152 | + | 318 | Protein_46 | IS5/IS1182 family transposase | - |
| G7B60_RS23480 () | 50412..50828 | + | 417 | WP_014839980.1 | fosfomycin resistance glutathione transferase FosA3 | - |
| G7B60_RS23485 () | 50833..51351 | - | 519 | WP_014839979.1 | hypothetical protein | - |
| G7B60_RS23490 () | 51351..52097 | - | 747 | WP_071448054.1 | winged helix-turn-helix domain-containing protein | - |
| G7B60_RS23495 () | 52103..52807 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| G7B60_RS23500 () | 52921..53697 | + | 777 | WP_001199192.1 | aminoglycoside N-acetyltransferase AAC(3)-IVa | - |
| G7B60_RS23505 () | 53926..54826 | + | 901 | Protein_52 | phosphotransferase | - |
| G7B60_RS23510 () | 54832..55197 | + | 366 | Protein_53 | AAC(3) family N-acetyltransferase | - |
| G7B60_RS23515 () | 55248..56000 | - | 753 | WP_000602738.1 | IS6 family transposase | - |
| G7B60_RS23520 () | 56086..57585 | + | 1500 | Protein_55 | Tn3 family transposase | - |
| G7B60_RS23525 () | 57621..57773 | + | 153 | Protein_56 | phenol hydroxylase | - |
| G7B60_RS23530 () | 57811..58296 | + | 486 | WP_006581703.1 | hypothetical protein | - |
| G7B60_RS23545 () | 59673..60488 | + | 816 | WP_001043260.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | - |
| G7B60_RS23550 () | 60575..60817 | + | 243 | Protein_60 | phosphoglucosamine mutase | - |
| G7B60_RS23560 () | 61053..62546 | - | 1494 | WP_001120888.1 | IS91-like element ISVsa3 family transposase | - |
| G7B60_RS23565 () | 62658..62963 | - | 306 | WP_001255015.1 | LysR family transcriptional regulator | - |
| G7B60_RS23570 () | 62991..64205 | - | 1215 | WP_000214122.1 | chloramphenicol/florfenicol efflux MFS transporter FloR | - |
| G7B60_RS24600 () | 64422..64868 | - | 447 | Protein_64 | DUF3363 domain-containing protein | - |
| G7B60_RS23580 () | 65337..66167 | - | 831 | Protein_65 | IS91-like element ISVsa3 family transposase | - |
| G7B60_RS23585 () | 66231..66935 | + | 705 | WP_001067784.1 | IS6-like element IS1006 family transposase | - |
| G7B60_RS23590 () | 67020..67421 | - | 402 | WP_046788546.1 | hypothetical protein | - |
| G7B60_RS23595 () | 67430..70381 | - | 2952 | WP_015344976.1 | Tn3-like element TnAs3 family transposase | - |
| G7B60_RS23600 () | 70384..70851 | - | 468 | WP_061093074.1 | recombinase family protein | - |
| G7B60_RS23605 () | 70902..71606 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| G7B60_RS23610 () | 71612..72853 | + | 1242 | Protein_71 | transposase | - |
| G7B60_RS23615 () | 72918..73622 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| G7B60_RS23620 () | 73812..74627 | - | 816 | WP_000018329.1 | aminoglycoside O-phosphotransferase APH(3')-Ia | - |
| G7B60_RS23625 () | 74778..75482 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| G7B60_RS23630 () | 75604..76509 | + | 906 | WP_000219391.1 | Mph(A) family macrolide 2'-phosphotransferase | - |
| G7B60_RS23635 () | 76506..77744 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| G7B60_RS23640 () | 77744..78328 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| G7B60_RS23645 () | 78821..79585 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| G7B60_RS23650 () | 79714..80418 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| G7B60_RS23655 () | 80475..80807 | - | 333 | Protein_80 | dihydropteroate synthase | - |
| G7B60_RS23660 () | 80801..81148 | - | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| G7B60_RS23665 () | 81312..82103 | - | 792 | WP_001206356.1 | ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2 | - |
| G7B60_RS23670 () | 82109..82399 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| G7B60_RS23675 () | 82511..83008 | - | 498 | WP_001083725.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | - |
| G7B60_RS23680 () | 83153..84166 | + | 1014 | WP_000845039.1 | class 1 integron integrase IntI1 | - |
| G7B60_RS23685 () | 84369..84719 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| G7B60_RS24605 () | 84845..84958 | + | 114 | Protein_87 | recombinase family protein | - |
| G7B60_RS23695 () | 85011..85715 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| G7B60_RS23700 () | 86018..86878 | + | 861 | WP_000027057.1 | class A broad-spectrum beta-lactamase TEM-1 | - |
| G7B60_RS23705 () | 87028..87126 | - | 99 | Protein_90 | IS1 family transposase | - |
| G7B60_RS23710 () | 87155..88465 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| G7B60_RS23715 () | 88750..89151 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| G7B60_RS23720 () | 89084..89341 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| G7B60_RS23725 () | 89434..90076 | - | 643 | Protein_94 | CPBP family intramembrane metalloprotease | - |
| G7B60_RS23730 () | 90890..92461 | - | 1572 | WP_000381395.1 | IS66 family transposase | - |
| G7B60_RS23735 () | 92481..92828 | - | 348 | WP_000624622.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| G7B60_RS23740 () | 92828..93505 | - | 678 | WP_165899058.1 | IS66-like element accessory protein TnpA | - |
| G7B60_RS23745 () | 93722..94579 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| G7B60_RS23750 () | 94572..95054 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| G7B60_RS23755 () | 95047..95121 | - | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| G7B60_RS23760 () | 95353..95610 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| G7B60_RS23765 () | 95894..96100 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 96087..96148 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - () | 96087..96148 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - () | 96087..96148 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - () | 96087..96148 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| G7B60_RS24610 () | 96404..96478 | - | 75 | Protein_103 | endonuclease | - |
| G7B60_RS23770 () | 96724..96936 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| G7B60_RS23775 () | 97072..97632 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| G7B60_RS23780 () | 97735..98595 | - | 861 | WP_000704514.1 | alpha/beta hydrolase | - |
| G7B60_RS23785 () | 98654..99400 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| G7B60_RS23790 () | 99420..104690 | - | 5271 | WP_000986962.1 | conjugative transfer relaxase/helicase TraI | - |
| G7B60_RS23795 () | 104772..104999 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| G7B60_RS23800 () | 104999..105397 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| G7B60_RS23805 () | 105406..107559 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| G7B60_RS23810 () | 107812..108543 | - | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| G7B60_RS23815 () | 108575..109072 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| G7B60_RS23820 () | 109088..111910 | - | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| G7B60_RS23825 () | 111907..113280 | - | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| G7B60_RS23830 () | 113280..113693 | - | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| G7B60_RS23835 () | 113647..113988 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| G7B60_RS23840 () | 113918..114463 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| G7B60_RS23845 () | 114450..114734 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| G7B60_RS23850 () | 114815..115129 | + | 315 | WP_165899060.1 | toxin ArtA | - |
| G7B60_RS23855 () | 115131..115478 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| G7B60_RS23860 () | 115494..116237 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| G7B60_RS23865 () | 116230..116487 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| G7B60_RS23870 () | 116514..118322 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| G7B60_RS23875 () | 118319..118957 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| G7B60_RS23880 () | 118966..119958 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| G7B60_RS23885 () | 119955..120587 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| G7B60_RS23890 () | 120584..120970 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| G7B60_RS23895 () | 120967..123594 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| G7B60_RS23900 () | 123754..123975 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| G7B60_RS23905 () | 124110..124625 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| G7B60_RS23910 () | 124622..124873 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| G7B60_RS23915 () | 124885..125115 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| G7B60_RS23920 () | 125069..125659 | - | 591 | WP_001376242.1 | conjugal transfer protein TraP | - |
| G7B60_RS23925 () | 125649..127076 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| G7B60_RS23930 () | 127076..127780 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| G7B60_RS23935 () | 127791..128357 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| G7B60_RS23940 () | 128379..128690 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| G7B60_RS23945 () | 128705..129070 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| G7B60_RS23950 () | 129103..129498 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| G7B60_RS23955 () | 129597..130286 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| G7B60_RS23960 () | 130473..130856 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| G7B60_RS23965 () | 131177..131779 | + | 603 | WP_000243712.1 | transglycosylase SLT domain-containing protein | - |
| G7B60_RS23970 () | 132076..132897 | - | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| G7B60_RS23975 () | 133015..133302 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| G7B60_RS23985 () | 134223..134381 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 134425..134456 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 134425..134456 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 134425..134456 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 134425..134456 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 135898..136095 | - | 198 | NuclAT_0 | - | - |
| - () | 135898..136095 | - | 198 | NuclAT_0 | - | - |
| - () | 135898..136095 | - | 198 | NuclAT_0 | - | - |
| - () | 135898..136095 | - | 198 | NuclAT_0 | - | - |
| G7B60_RS23995 () | 135907..136095 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| G7B60_RS24000 () | 136107..136826 | - | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| G7B60_RS24005 () | 136823..137257 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| G7B60_RS24010 () | 137312..137509 | - | 198 | Protein_151 | hypothetical protein | - |
| G7B60_RS24015 () | 137537..137770 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| G7B60_RS24020 () | 137838..138377 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| G7B60_RS24615 () | 138403..138609 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| G7B60_RS24035 () | 139705..140676 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| G7B60_RS24040 () | 140676..141842 | - | 1167 | WP_001238646.1 | plasmid-partitioning protein SopA | - |
| G7B60_RS24045 () | 142142..142839 | - | 698 | Protein_157 | IS1-like element IS1A family transposase | - |
| G7B60_RS24050 () | 143324..145525 | - | 2202 | WP_000973520.1 | ferric aerobactin receptor IutA | - |
| G7B60_RS24055 () | 145607..146884 | - | 1278 | WP_000750130.1 | NADPH-dependent L-lysine N(6)-monooxygenase | - |
| G7B60_RS24060 () | 146881..148623 | - | 1743 | WP_001015721.1 | aerobactin synthase IucC | - |
| G7B60_RS24065 () | 148623..149570 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | - |
| G7B60_RS24070 () | 149571..151295 | - | 1725 | WP_000602863.1 | aerobactin synthase IucA | - |
| G7B60_RS24075 () | 151431..152624 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| G7B60_RS24080 () | 153004..153384 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| G7B60_RS24085 () | 153725..154138 | - | 414 | Protein_165 | phosphopyruvate hydratase | - |
| G7B60_RS24090 () | 154136..154393 | + | 258 | Protein_166 | Tn3 family transposase | - |
| G7B60_RS24095 () | 154627..155484 | - | 858 | WP_000968139.1 | iron/manganese ABC transporter permease subunit SitD | - |
| G7B60_RS24100 () | 155481..156338 | - | 858 | WP_001101723.1 | iron/manganese ABC transporter permease subunit SitC | - |
| G7B60_RS24105 () | 156335..157162 | - | 828 | WP_000983710.1 | iron/manganese ABC transporter ATP-binding protein SitB | - |
| G7B60_RS24110 () | 157162..158076 | - | 915 | WP_000949004.1 | iron/manganese ABC transporter substrate-binding protein SitA | - |
| G7B60_RS24115 () | 158432..159129 | + | 698 | Protein_171 | IS1 family transposase | - |
| G7B60_RS24120 () | 159309..159822 | - | 514 | Protein_172 | DUF4113 domain-containing protein | - |
| G7B60_RS24125 () | 159883..159987 | - | 105 | Protein_173 | AAA family ATPase | - |
| G7B60_RS24130 () | 159989..160312 | - | 324 | Protein_174 | helix-turn-helix domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|