MGE detailed information
MGE type: Mobilizable plasmid MGE length: 127240 bp
Accession: NZ_CP047161 Location: 1..127240 Organism: Klebsiella pneumoniae strain KP19-2029 Replicon: plasmid pKP19-2029-KPC2
Accession: NZ_CP047161 Location: 1..127240 Organism: Klebsiella pneumoniae strain KP19-2029 Replicon: plasmid pKP19-2029-KPC2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GSU00_RS26925 () | 1..858 | + | 858 | WP_142295464.1 | incFII family plasmid replication initiator RepA | - |
| GSU00_RS26930 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| GSU00_RS26935 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| GSU00_RS26940 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| GSU00_RS26945 () | 3383..3798 | + | 416 | Protein_5 | IS1 family transposase IS1R | Transposase |
| GSU00_RS26950 () | 3834..4379 | - | 546 | Protein_6 | Tn3 family transposase TnpA_Tn3 | Transposase |
| GSU00_RS26955 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GSU00_RS26960 () | 5161..5418 | - | 258 | WP_101307356.1 | IS6 family transposase IS15 | Transposase |
| GSU00_RS26965 () | 5418..6122 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| GSU00_RS26970 () | 6133..6699 | - | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| GSU00_RS26975 () | 6721..7032 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| GSU00_RS26980 () | 7047..7412 | - | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| GSU00_RS26985 () | 7446..7673 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| GSU00_RS26990 () | 7767..8453 | - | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| GSU00_RS26995 () | 8644..9027 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| GSU00_RS27000 () | 9304..9951 | + | 648 | WP_015059008.1 | hypothetical protein | VF |
| GSU00_RS27005 () | 10248..11069 | - | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| GSU00_RS27010 () | 11180..11476 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| GSU00_RS28445 () | 11776..12153 | + | 378 | Protein_19 | hypothetical protein | - |
| GSU00_RS27020 () | 12391..12549 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 12593..12817 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 12593..12817 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 12593..12817 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 12593..12817 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| GSU00_RS27025 () | 12829..13548 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| GSU00_RS27030 () | 13545..13979 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| GSU00_RS27035 () | 14048..16071 | - | 2024 | Protein_23 | ParB/RepB/Spo0J family partition protein | - |
| GSU00_RS27040 () | 16132..16365 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| GSU00_RS27045 () | 16423..16950 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| GSU00_RS27055 () | 17793..18356 | - | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| GSU00_RS27060 () | 18403..19764 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| GSU00_RS27065 () | 19816..20046 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| GSU00_RS27070 () | 21446..23113 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| GSU00_RS27075 () | 23427..23618 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| GSU00_RS27080 () | 23615..24037 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| GSU00_RS27085 () | 24084..24509 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| GSU00_RS28450 () | 24927..25703 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| GSU00_RS27100 () | 25754..26188 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| GSU00_RS27105 () | 26202..26423 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| GSU00_RS27110 () | 26424..27107 | - | 684 | WP_000085883.1 | DNA methylase | - |
| GSU00_RS27115 () | 27184..27477 | - | 294 | WP_032146011.1 | hypothetical protein | - |
| GSU00_RS27120 () | 27624..28586 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| GSU00_RS27125 () | 28589..28939 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| GSU00_RS27130 () | 29062..29343 | - | 282 | WP_001333089.1 | hypothetical protein | - |
| GSU00_RS27135 () | 29471..29705 | - | 235 | Protein_41 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GSU00_RS27140 () | 31154..31294 | - | 141 | WP_071557810.1 | hypothetical protein | - |
| GSU00_RS27145 () | 31285..31989 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| GSU00_RS27150 () | 32077..32358 | + | 282 | WP_015059004.1 | sodium/hydrogen exchanger | - |
| GSU00_RS27155 () | 32439..33194 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| GSU00_RS27160 () | 33364..34224 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| GSU00_RS27165 () | 34407..34943 | - | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| GSU00_RS27170 () | 35035..35223 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| GSU00_RS27175 () | 35233..35850 | + | 618 | Protein_49 | IS91 family transposase ISSbo1 | Transposase |
| GSU00_RS27180 () | 35901..36604 | - | 704 | Protein_50 | IS6 family transposase IS15DII | Transposase |
| GSU00_RS27185 () | 36669..37259 | + | 591 | Protein_51 | IS91 family transposase ISSbo1 | Transposase |
| GSU00_RS27190 () | 37715..38418 | + | 704 | Protein_52 | IS6 family transposase IS15DI | Transposase |
| GSU00_RS27195 () | 38484..39002 | + | 519 | WP_014839979.1 | hypothetical protein | - |
| GSU00_RS27200 () | 39007..39423 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| GSU00_RS27205 () | 39809..40512 | + | 704 | Protein_55 | IS6 family transposase IS15DII | Transposase |
| GSU00_RS27210 () | 40592..41041 | + | 450 | Protein_56 | PAS domain-containing protein | - |
| GSU00_RS27215 () | 41109..42206 | - | 1098 | Protein_57 | TonB-dependent receptor | - |
| GSU00_RS27220 () | 42263..43231 | - | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| GSU00_RS27225 () | 43266..44141 | - | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| GSU00_RS27230 () | 44391..44582 | - | 192 | Protein_60 | transposase | - |
| GSU00_RS27235 () | 44652..45357 | + | 706 | Protein_61 | IS6 family transposase IS15DI | Transposase |
| GSU00_RS27240 () | 45411..45734 | - | 324 | Protein_62 | class II aldolase/adducin family protein | - |
| GSU00_RS27245 () | 45727..46976 | - | 1250 | Protein_63 | four-carbon acid sugar kinase family protein | - |
| GSU00_RS27250 () | 46988..47885 | - | 898 | Protein_64 | NAD(P)-dependent oxidoreductase | - |
| GSU00_RS27255 () | 48146..48907 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| GSU00_RS27260 () | 48928..49788 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| GSU00_RS28455 () | 49925..49993 | + | 69 | Protein_67 | IS6 family transposase | - |
| GSU00_RS27265 () | 50029..51927 | - | 1899 | Protein_68 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| GSU00_RS27270 () | 51993..52697 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GSU00_RS27275 () | 52749..53210 | + | 462 | Protein_70 | Tn3 family transposase TnpR_Tn3 | Transposase |
| GSU00_RS27280 () | 53333..54313 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| GSU00_RS27285 () | 54589..55470 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| GSU00_RS27290 () | 55720..56601 | - | 882 | Protein_73 | IS1182 family transposase ISKpn6 | Transposase |
| GSU00_RS28460 () | 56705..57001 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
| GSU00_RS28465 () | 57047..57202 | - | 156 | WP_013213988.1 | hypothetical protein | - |
| GSU00_RS27295 () | 57330..57755 | - | 426 | WP_013213989.1 | antirestriction protein | - |
| GSU00_RS27300 () | 57866..58144 | - | 279 | WP_013213990.1 | hypothetical protein | - |
| GSU00_RS27305 () | 58678..59295 | - | 618 | Protein_78 | replication protein | - |
| GSU00_RS27310 () | 59687..60247 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| GSU00_RS27315 () | 60251..61324 | + | 1074 | Protein_80 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| GSU00_RS27320 () | 61377..62081 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GSU00_RS27325 () | 62146..63318 | - | 1173 | Protein_82 | transposase | - |
| GSU00_RS27330 () | 63393..64061 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| GSU00_RS27335 () | 64097..64333 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| GSU00_RS27340 () | 64330..64692 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| GSU00_RS27345 () | 64710..66404 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| GSU00_RS27350 () | 66456..66878 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| GSU00_RS27355 () | 66914..67189 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| GSU00_RS27360 () | 67203..67553 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| GSU00_RS27365 () | 67625..68059 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| GSU00_RS27370 () | 68138..69142 | + | 1005 | WP_159154139.1 | IS110 family transposase IS5075 | Transposase |
| GSU00_RS27375 () | 69422..69694 | - | 273 | Protein_92 | IS5 family transposase ISPan1 | Transposase |
| GSU00_RS27380 () | 69723..70419 | - | 697 | Protein_93 | IS1 family transposase ISKpn14 | Transposase |
| GSU00_RS27385 () | 70675..71697 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| GSU00_RS27390 () | 71682..73244 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| GSU00_RS27395 () | 73318..73734 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| GSU00_RS27400 () | 73731..73961 | - | 231 | WP_001261282.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| GSU00_RS28470 () | 73918..74379 | + | 462 | WP_014343465.1 | hypothetical protein | - |
| GSU00_RS27405 () | 74540..75484 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| GSU00_RS27410 () | 75521..75913 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| GSU00_RS27415 () | 75971..76492 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| GSU00_RS27420 () | 76538..76741 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| GSU00_RS27425 () | 76771..77775 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| GSU00_RS27430 () | 77959..78738 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| GSU00_RS27435 () | 78784..79041 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| GSU00_RS28475 () | 79170..79283 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| GSU00_RS27440 () | 79819..80685 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| GSU00_RS27445 () | 81795..83000 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| GSU00_RS27450 () | 83000..83974 | + | 975 | WP_011977819.1 | ParB/RepB/Spo0J family partition protein | - |
| GSU00_RS27455 () | 84056..85327 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| GSU00_RS27460 () | 85327..85758 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| GSU00_RS27465 () | 86165..87652 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| GSU00_RS27470 () | 87901..88872 | + | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| GSU00_RS27475 () | 88875..89546 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| GSU00_RS27480 () | 89609..89839 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| GSU00_RS27485 () | 90276..90977 | + | 702 | WP_151488309.1 | DNA methylase | - |
| GSU00_RS27490 () | 90977..91198 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| GSU00_RS27495 () | 91208..91627 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| GSU00_RS27500 () | 91681..92448 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| GSU00_RS28480 () | 93129..93557 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| GSU00_RS27510 () | 93600..94106 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| GSU00_RS27515 () | 94149..94340 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| GSU00_RS27520 () | 94528..94782 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| GSU00_RS27525 () | 94817..95137 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| GSU00_RS27530 () | 95817..96044 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| GSU00_RS27535 () | 96136..96366 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| GSU00_RS27540 () | 96418..97773 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| GSU00_RS27545 () | 97821..98384 | + | 564 | WP_014343514.1 | methyltransferase | - |
| GSU00_RS27550 () | 99217..99759 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| GSU00_RS27555 () | 99808..100056 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| GSU00_RS27560 () | 100126..102183 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| GSU00_RS27565 () | 102228..102659 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| GSU00_RS27570 () | 102656..103384 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| GSU00_RS27575 () | 103381..103707 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| GSU00_RS27580 () | 103763..104137 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| GSU00_RS27585 () | 104365..104523 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| GSU00_RS27590 () | 105216..105488 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| GSU00_RS27595 () | 105485..105835 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| GSU00_RS27600 () | 105850..106167 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| GSU00_RS27605 () | 107008..107364 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| GSU00_RS27610 () | 107425..107637 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| GSU00_RS27615 () | 107648..107872 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| GSU00_RS27620 () | 107953..108273 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GSU00_RS27625 () | 108263..108541 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| GSU00_RS27635 () | 108823..109527 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GSU00_RS27640 () | 109856..110806 | + | 951 | WP_015493085.1 | Recombination-promoting nuclease RpnA | VF |
| GSU00_RS27645 () | 110803..111414 | - | 612 | WP_015493086.1 | DUF2913 family protein | - |
| GSU00_RS27650 () | 111411..111806 | - | 396 | WP_015493087.1 | hypothetical protein | - |
| GSU00_RS27655 () | 111859..112251 | - | 393 | Protein_149 | 3'-5' exonuclease | - |
| GSU00_RS27660 () | 112320..113300 | + | 981 | WP_000019445.1 | IS5 family transposase ISKpn26 | Transposase |
| GSU00_RS27665 () | 113447..113824 | + | 378 | Protein_151 | restriction endonuclease | - |
| GSU00_RS27670 () | 113952..114509 | + | 558 | WP_042934582.1 | hypothetical protein | - |
| GSU00_RS27675 () | 114978..115682 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GSU00_RS27680 () | 115688..115828 | + | 141 | WP_001044210.1 | hypothetical protein | - |
| GSU00_RS27685 () | 116314..117051 | + | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| GSU00_RS27690 () | 117048..117272 | + | 225 | WP_000743213.1 | hypothetical protein | - |
| GSU00_RS27695 () | 117394..117570 | + | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| GSU00_RS27700 () | 117752..118756 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| GSU00_RS27705 () | 118835..121801 | - | 2967 | WP_042863651.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| GSU00_RS27710 () | 121804..121869 | - | 66 | Protein_160 | helix-turn-helix domain-containing protein | - |
| GSU00_RS27715 () | 121922..122626 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GSU00_RS27720 () | 122690..122851 | + | 162 | Protein_162 | DNA helicase | - |
| GSU00_RS27725 () | 122871..123617 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| GSU00_RS27730 () | 123672..124232 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| GSU00_RS27735 () | 124364..124564 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| GSU00_RS27740 () | 124950..125549 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| GSU00_RS27745 () | 125713..125943 | + | 231 | WP_001736714.1 | hypothetical protein | - |
| - () | 126144..126203 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 126144..126203 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 126144..126203 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 126144..126203 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| GSU00_RS27750 () | 126248..126397 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| GSU00_RS27755 () | 126681..126929 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|