MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 104713 bp
Accession: NZ_CP045598 Location: 2536148..2640860 Organism: Enterococcus faecalis strain TK-P4B Replicon: chromosome
Accession: NZ_CP045598 Location: 2536148..2640860 Organism: Enterococcus faecalis strain TK-P4B Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GFB65_RS11990 () | 2531224..2532492 | - | 1269 | WP_194848779.1 | competence/damage-inducible protein A | - |
| GFB65_RS11995 () | 2532660..2533859 | + | 1200 | WP_002370127.1 | hypothetical protein | - |
| GFB65_RS12000 () | 2533939..2534568 | - | 630 | WP_002354854.1 | NAD(P)-dependent oxidoreductase | - |
| GFB65_RS12005 () | 2534627..2535052 | - | 426 | WP_002383201.1 | Rrf2 family transcriptional regulator | - |
| GFB65_RS12010 () | 2535141..2535689 | - | 549 | WP_002386241.1 | YccF domain-containing protein | - |
| GFB65_RS12015 () | 2535688..2536479 | + | 792 | WP_002354848.1 | hypothetical protein | - |
| GFB65_RS12020 () | 2536532..2537668 | - | 1137 | WP_002370129.1 | ArgE/DapE family deacylase | - |
| GFB65_RS12025 () | 2537798..2538682 | - | 885 | WP_002370130.1 | RsiV family protein | - |
| GFB65_RS12030 () | 2538707..2539204 | - | 498 | WP_002360979.1 | RNA polymerase sigma factor | - |
| GFB65_RS12035 () | 2539441..2540922 | - | 1482 | WP_002354844.1 | helix-turn-helix domain-containing protein | - |
| GFB65_RS12040 () | 2540897..2541382 | - | 486 | WP_002354843.1 | hypothetical protein | - |
| GFB65_RS12045 () | 2541487..2542566 | - | 1080 | WP_048941299.1 | DUF916 and DUF3324 domain-containing protein | - |
| GFB65_RS12050 () | 2542672..2543430 | - | 759 | WP_002383195.1 | WxL domain-containing protein | - |
| GFB65_RS12055 () | 2543431..2544231 | - | 801 | WP_002385162.1 | WxL domain-containing protein | - |
| GFB65_RS12060 () | 2544236..2544970 | - | 735 | WP_002354838.1 | WxL domain-containing protein | - |
| GFB65_RS12065 () | 2544927..2545316 | - | 390 | WP_010713699.1 | LPXTG cell wall anchor domain-containing protein | - |
| GFB65_RS12070 () | 2545336..2550195 | - | 4860 | WP_194848780.1 | hypothetical protein | - |
| GFB65_RS12075 () | 2550562..2551575 | - | 1014 | WP_085370389.1 | alpha/beta hydrolase | - |
| GFB65_RS12080 () | 2551741..2552286 | + | 546 | WP_194848781.1 | Isochorismatase family protein YecD | VF |
| GFB65_RS12085 () | 2552500..2553183 | - | 684 | WP_002365411.1 | antiholin-like protein LrgB | - |
| GFB65_RS12090 () | 2553180..2553599 | - | 420 | WP_002354829.1 | antiholin-like murein hydrolase modulator LrgA | - |
| GFB65_RS12095 () | 2553751..2554479 | - | 729 | WP_002367483.1 | Sensory transduction protein LytR | VF |
| GFB65_RS12100 () | 2554460..2556208 | - | 1749 | WP_002390682.1 | Sensor histidine kinase YpdA | VF |
| GFB65_RS12105 () | 2556321..2557139 | - | 819 | WP_002354826.1 | membrane protein | - |
| GFB65_RS12110 () | 2557152..2557823 | - | 672 | WP_002354825.1 | ABC transporter permease subunit | - |
| GFB65_RS12115 () | 2557820..2558542 | - | 723 | WP_002354824.1 | Methionine import ATP-binding protein MetN | VF |
| GFB65_RS12120 () | 2558904..2559302 | - | 399 | WP_002386234.1 | OsmC family protein | - |
| GFB65_RS12125 () | 2559503..2559772 | + | 270 | WP_002354822.1 | 30S ribosomal protein S14 | - |
| GFB65_RS12130 () | 2559883..2560032 | + | 150 | WP_002354818.1 | 50S ribosomal protein L33 | - |
| GFB65_RS12135 () | 2560048..2561022 | + | 975 | WP_002365414.1 | GTP-binding protein | - |
| GFB65_RS12140 () | 2561057..2561179 | + | 123 | WP_002383181.1 | putative metal homeostasis protein | - |
| GFB65_RS12145 () | 2561200..2562735 | + | 1536 | WP_002385152.1 | High-affinity zinc uptake system binding-protein ZnuA | VF |
| GFB65_RS12150 () | 2562793..2563767 | - | 975 | WP_048941276.1 | tRNA-dihydrouridine synthase | - |
| GFB65_RS12155 () | 2563955..2564725 | - | 771 | WP_002354811.1 | ABC transporter permease | - |
| GFB65_RS12160 () | 2564718..2565653 | - | 936 | WP_002354809.1 | putative ABC transporter ATP-binding protein YadG | VF |
| GFB65_RS12165 () | 2565911..2566330 | + | 420 | WP_002354802.1 | PTS mannose transporter subunit IIA | - |
| GFB65_RS12170 () | 2566343..2566834 | + | 492 | WP_002354800.1 | PTS sugar transporter subunit IIB | - |
| GFB65_RS12175 () | 2566851..2567666 | + | 816 | WP_002365419.1 | PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC | - |
| GFB65_RS12180 () | 2567663..2568490 | + | 828 | WP_048941280.1 | PTS system mannose/fructose/sorbose family transporter subunit IID | - |
| GFB65_RS12185 () | 2568638..2571157 | + | 2520 | WP_033627001.1 | Transcriptional regulatory protein DagR | VF |
| GFB65_RS12190 () | 2571357..2572529 | - | 1173 | WP_163402559.1 | DUF262 domain-containing protein | - |
| GFB65_RS12195 () | 2572519..2573130 | - | 612 | WP_163402557.1 | hypothetical protein | - |
| GFB65_RS12200 () | 2573130..2573921 | - | 792 | Protein_2377 | DNA cytosine methyltransferase | - |
| GFB65_RS12205 () | 2573999..2575161 | + | 1163 | WP_113848076.1 | IS3 family transposase IS1485 | Transposase |
| GFB65_RS12210 () | 2575326..2575517 | + | 192 | WP_010784100.1 | hypothetical protein | - |
| GFB65_RS12215 () | 2575687..2575902 | + | 216 | WP_010709166.1 | leucocin A/sakacin P family class II bacteriocin | - |
| GFB65_RS12220 () | 2575903..2576244 | + | 342 | WP_002367792.1 | bacteriocin immunity protein | - |
| GFB65_RS12230 () | 2578055..2578543 | - | 489 | WP_174098687.1 | PTS glucose transporter subunit IIA | - |
| GFB65_RS12235 () | 2578570..2580135 | - | 1566 | WP_010742395.1 | PTS transporter subunit EIIC | - |
| GFB65_RS12240 () | 2580207..2581532 | - | 1326 | WP_010742396.1 | 6-phospho-alpha-glucosidase | - |
| GFB65_RS12245 () | 2581653..2582396 | - | 744 | WP_174103766.1 | MurR/RpiR family transcriptional regulator | - |
| GFB65_RS12250 () | 2582519..2583704 | - | 1186 | Protein_2387 | IS256 family transposase ISLgar5 | Transposase |
| GFB65_RS12255 () | 2583798..2584400 | - | 603 | Protein_2388 | DUF1565 domain-containing protein | - |
| GFB65_RS12260 () | 2584609..2587725 | - | 3117 | WP_194848782.1 | DEAD/DEAH box helicase family protein | - |
| GFB65_RS12265 () | 2587760..2589565 | - | 1806 | WP_194848783.1 | site-specific DNA-methyltransferase | - |
| GFB65_RS12270 () | 2589569..2590126 | - | 558 | WP_194848784.1 | hypothetical protein | - |
| GFB65_RS12275 () | 2590127..2593321 | - | 3195 | WP_194848785.1 | DEAD/DEAH box helicase family protein | - |
| GFB65_RS12280 () | 2593357..2593620 | - | 264 | WP_194848997.1 | plasmid replication protein | - |
| GFB65_RS12285 () | 2593795..2594475 | - | 681 | WP_194848786.1 | IS6 family transposase IS1216E | Transposase |
| GFB65_RS12290 () | 2595098..2595520 | + | 423 | WP_194848787.1 | YxeA family protein | - |
| GFB65_RS12295 () | 2595739..2595834 | + | 96 | Protein_2396 | IS6 family transposase IS1216 | Transposase |
| GFB65_RS12300 () | 2595935..2597233 | - | 1299 | WP_002369933.1 | polysaccharide deacetylase family protein | - |
| GFB65_RS12305 () | 2597402..2598082 | + | 681 | WP_194848788.1 | IS6 family transposase IS1216E | Transposase |
| GFB65_RS12310 () | 2598330..2599322 | + | 993 | WP_194848789.1 | IS30 family transposase ISSau1 | Transposase |
| GFB65_RS12315 () | 2599465..2600635 | + | 1171 | Protein_2400 | IS256 family transposase IS1310 | Transposase |
| GFB65_RS12320 () | 2600805..2602919 | - | 2115 | WP_142957692.1 | putative ATP-dependent Clp protease ATP-binding subunit | VF |
| GFB65_RS12325 () | 2603133..2603363 | + | 231 | WP_194848790.1 | hypothetical protein | - |
| GFB65_RS12330 () | 2603961..2604146 | + | 186 | WP_002362398.1 | hypothetical protein | - |
| GFB65_RS12335 () | 2604131..2604322 | + | 192 | WP_025186373.1 | DpnD/PcfM family protein | - |
| GFB65_RS12340 () | 2604346..2604936 | + | 591 | WP_194848791.1 | hypothetical protein | - |
| GFB65_RS12345 () | 2605041..2605814 | + | 774 | WP_194848792.1 | hypothetical protein | - |
| GFB65_RS12350 () | 2605814..2607157 | + | 1344 | WP_194848793.1 | PcfJ domain-containing protein | - |
| GFB65_RS12355 () | 2607434..2607616 | - | 183 | WP_002362405.1 | putative holin-like toxin | - |
| GFB65_RS12360 () | 2607694..2608044 | - | 351 | WP_010784126.1 | hypothetical protein | - |
| GFB65_RS12365 () | 2608077..2609762 | - | 1686 | WP_194848794.1 | relaxase/mobilization nuclease domain-containing protein | - |
| GFB65_RS12370 () | 2609763..2610119 | - | 357 | WP_002365872.1 | plasmid mobilization relaxosome protein MobC | - |
| GFB65_RS12375 () | 2610365..2610637 | - | 273 | WP_002362409.1 | LtrD | - |
| GFB65_RS12380 () | 2610670..2611161 | - | 492 | Protein_2413 | DNA primase | - |
| GFB65_RS12385 () | 2611239..2612401 | + | 1163 | WP_113848076.1 | IS3 family transposase IS1485 | Transposase |
| GFB65_RS12390 () | 2612599..2612832 | - | 234 | WP_048941462.1 | helix-turn-helix transcriptional regulator | - |
| GFB65_RS12395 () | 2612939..2613160 | + | 222 | WP_048941464.1 | hypothetical protein | VF |
| GFB65_RS12400 () | 2613484..2613876 | - | 393 | WP_002354786.1 | 30S ribosomal protein S9 | - |
| GFB65_RS12405 () | 2613890..2614333 | - | 444 | WP_002365424.1 | 50S ribosomal protein L13 | - |
| GFB65_RS12410 () | 2614555..2615022 | - | 468 | WP_002354782.1 | DNA starvation/stationary phase protection protein | - |
| GFB65_RS12415 () | 2615150..2615869 | - | 720 | WP_010818596.1 | DUF5105 domain-containing protein | - |
| GFB65_RS12420 () | 2615953..2617473 | - | 1521 | WP_194848795.1 | gluconokinase | - |
| GFB65_RS12425 () | 2617582..2618274 | + | 693 | WP_002360938.1 | A24 family peptidase | - |
| GFB65_RS12430 () | 2618323..2621976 | - | 3654 | WP_002354777.1 | DNA-directed RNA polymerase subunit beta' | - |
| GFB65_RS12435 () | 2622143..2625757 | - | 3615 | WP_002389470.1 | DNA-directed RNA polymerase subunit beta | - |
| GFB65_RS12440 () | 2626128..2626469 | - | 342 | WP_002360937.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| GFB65_RS12445 () | 2626469..2626699 | - | 231 | WP_002354773.1 | hypothetical protein | Antitoxin Detail |
| GFB65_RS12450 () | 2626873..2627088 | - | 216 | WP_002354768.1 | zinc ribbon domain-containing protein | - |
| GFB65_RS12455 () | 2627227..2628219 | + | 993 | WP_002358973.1 | biotin--[acetyl-CoA-carboxylase] ligase | - |
| GFB65_RS12460 () | 2628483..2629136 | - | 654 | WP_194848796.1 | lytic polysaccharide monooxygenase | - |
| GFB65_RS12465 () | 2629717..2631333 | + | 1617 | WP_002372620.1 | Biofilm regulatory protein A | VF |
| GFB65_RS12470 () | 2631565..2631747 | + | 183 | WP_002424907.1 | putative holin-like toxin | Toxin Detail |
| - () | 2631680..2631864 | - | 185 | NuclAT_7 | - | Antitoxin Detail |
| - () | 2631721..2631864 | - | 144 | NuclAT_9 | - | - |
| GFB65_RS12475 () | 2631866..2632006 | + | 141 | WP_073340360.1 | putative holin-like toxin | Toxin Detail |
| - () | 2631939..2632140 | - | 202 | NuclAT_6 | - | Antitoxin Detail |
| GFB65_RS12480 () | 2632234..2632377 | + | 144 | WP_002396786.1 | putative holin-like toxin | Toxin Detail |
| - () | 2632309..2632571 | - | 263 | NuclAT_8 | - | Antitoxin Detail |
| - () | 2632521..2632570 | + | 50 | NuclAT_10 | - | - |
| GFB65_RS12485 () | 2632572..2637263 | - | 4692 | WP_194848797.1 | WxL domain-containing protein | - |
| GFB65_RS12490 () | 2637612..2640608 | - | 2997 | WP_194848798.1 | WxL domain-containing protein | - |
| GFB65_RS12495 () | 2640939..2644811 | - | 3873 | WP_194848799.1 | WxL domain-containing protein | - |
| GFB65_RS12500 () | 2644798..2645139 | - | 342 | WP_002381032.1 | LPXTG cell wall anchor domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|