MGE detailed information
MGE type: Conjugative plasmid MGE length: 79831 bp
Accession: NZ_CP044156 Location: 1..79831 Organism: Shigella flexneri strain AR-0424 Replicon: plasmid pAR-0424-1
Accession: NZ_CP044156 Location: 1..79831 Organism: Shigella flexneri strain AR-0424 Replicon: plasmid pAR-0424-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F4V36_RS23410 (125) | 125..421 | + | 297 | Protein_0 | hypothetical protein | - |
| F4V36_RS23415 (740) | 740..865 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| F4V36_RS26330 (807) | 807..956 | - | 150 | Protein_2 | plasmid maintenance protein Mok | - |
| F4V36_RS23420 (978) | 978..1157 | + | 180 | WP_001334662.1 | hypothetical protein | - |
| - (942) | 942..1166 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (942) | 942..1166 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (942) | 942..1166 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (942) | 942..1166 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| F4V36_RS23425 (1135) | 1135..1897 | - | 763 | Protein_4 | plasmid SOS inhibition protein A | - |
| F4V36_RS23430 (1894) | 1894..2328 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| F4V36_RS23435 (2382) | 2382..4340 | - | 1959 | WP_112324844.1 | ParB/RepB/Spo0J family partition protein | - |
| F4V36_RS23440 (4404) | 4404..4637 | - | 234 | WP_000005971.1 | DUF905 domain-containing protein | - |
| F4V36_RS23445 (4693) | 4693..5214 | - | 522 | WP_033807850.1 | single-stranded DNA-binding protein | - |
| F4V36_RS26335 (5513) | 5513..5956 | + | 444 | Protein_9 | hypothetical protein | - |
| F4V36_RS23465 (6042) | 6042..6605 | - | 564 | WP_016240496.1 | class I SAM-dependent methyltransferase | - |
| F4V36_RS23470 (6651) | 6651..8012 | - | 1362 | WP_000170671.1 | DUF3560 domain-containing protein | - |
| F4V36_RS23475 (8064) | 8064..8294 | - | 231 | WP_000218647.1 | hypothetical protein | - |
| F4V36_RS23485 (9332) | 9332..9523 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| F4V36_RS23490 (9520) | 9520..9942 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| F4V36_RS23495 (9989) | 9989..10414 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| F4V36_RS25755 (10832) | 10832..11608 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| F4V36_RS23515 (11659) | 11659..12093 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| F4V36_RS23520 (12107) | 12107..12328 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| F4V36_RS23525 (12329) | 12329..13012 | - | 684 | WP_000085883.1 | DNA methylase | - |
| F4V36_RS23535 (13089) | 13089..13382 | - | 294 | WP_032146011.1 | hypothetical protein | - |
| F4V36_RS23540 (13529) | 13529..14491 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| F4V36_RS23545 (14494) | 14494..14844 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| F4V36_RS23550 (14967) | 14967..15248 | - | 282 | WP_001333089.1 | hypothetical protein | - |
| F4V36_RS23555 (15376) | 15376..15610 | - | 235 | Protein_24 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| F4V36_RS23580 (18519) | 18519..19256 | - | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| F4V36_RS23585 (19382) | 19382..19477 | - | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| F4V36_RS23590 (19612) | 19612..20316 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| F4V36_RS23600 (20438) | 20438..21343 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| F4V36_RS23605 (21340) | 21340..22578 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| F4V36_RS23610 (22578) | 22578..23162 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| F4V36_RS23625 (23655) | 23655..24419 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| F4V36_RS25765 (24537) | 24537..24602 | - | 66 | Protein_33 | EAL domain-containing protein | - |
| F4V36_RS23635 (24646) | 24646..24951 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| F4V36_RS23640 (24962) | 24962..26167 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| F4V36_RS23645 (26323) | 26323..26526 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| F4V36_RS23655 (26654) | 26654..27493 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| F4V36_RS23660 (27487) | 27487..27834 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| F4V36_RS23665 (28040) | 28040..28828 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| F4V36_RS23670 (28959) | 28959..29432 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| F4V36_RS23675 (29590) | 29590..30603 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| F4V36_RS23685 (30806) | 30806..31156 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| F4V36_RS23690 (31355) | 31355..32059 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| F4V36_RS23695 (32358) | 32358..33218 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| F4V36_RS23700 (33368) | 33368..33466 | - | 99 | Protein_45 | IS1 family transposase | - |
| F4V36_RS23705 (33495) | 33495..34805 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| F4V36_RS23710 (35090) | 35090..35491 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| F4V36_RS23715 (35424) | 35424..35681 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| F4V36_RS23720 (35774) | 35774..36427 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| F4V36_RS25770 (36525) | 36525..36665 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| F4V36_RS23730 (37366) | 37366..38223 | - | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| F4V36_RS23735 (38216) | 38216..38290 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| F4V36_RS23745 (38535) | 38535..38783 | - | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| F4V36_RS23750 (39068) | 39068..39217 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (39262) | 39262..39321 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (39262) | 39262..39321 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (39262) | 39262..39321 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (39262) | 39262..39321 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| F4V36_RS23760 (39464) | 39464..39937 | - | 474 | WP_016240489.1 | hypothetical protein | - |
| F4V36_RS23765 (40092) | 40092..40682 | - | 591 | WP_033807967.1 | DUF2726 domain-containing protein | - |
| F4V36_RS23770 (40720) | 40720..40929 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| F4V36_RS23775 (40975) | 40975..41436 | - | 462 | WP_001233850.1 | thermonuclease family protein | - |
| F4V36_RS23780 (41682) | 41682..41894 | - | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| F4V36_RS23785 (42026) | 42026..42586 | - | 561 | WP_033807966.1 | fertility inhibition protein FinO | - |
| F4V36_RS23790 (42641) | 42641..43387 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| F4V36_RS23795 (43407) | 43407..48676 | - | 5270 | Protein_62 | Multifunctional conjugation protein TraI | Relaxase |
| F4V36_RS23800 (48676) | 48676..50955 | - | 2280 | WP_151106457.1 | type IV conjugative transfer system coupling protein TraD | - |
| F4V36_RS23805 (51006) | 51006..51743 | - | 738 | WP_012881122.1 | hypothetical protein | - |
| F4V36_RS23810 (51946) | 51946..52677 | - | 732 | WP_012881123.1 | conjugal transfer complement resistance protein TraT | - |
| F4V36_RS23815 (52691) | 52691..53200 | - | 510 | WP_000628111.1 | conjugal transfer entry exclusion protein TraS | - |
| F4V36_RS23820 (53197) | 53197..56022 | - | 2826 | WP_033807963.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| F4V36_RS23825 (56019) | 56019..57391 | - | 1373 | Protein_68 | conjugal transfer protein TraH | - |
| F4V36_RS23830 (57378) | 57378..57770 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| F4V36_RS23835 (57751) | 57751..58098 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| F4V36_RS23840 (58028) | 58028..58572 | - | 545 | Protein_71 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| F4V36_RS23845 (58559) | 58559..58843 | - | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| F4V36_RS23850 (58924) | 58924..59259 | + | 336 | WP_001620807.1 | hypothetical protein | - |
| F4V36_RS23855 (59240) | 59240..59581 | - | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| F4V36_RS23860 (59595) | 59595..60338 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| F4V36_RS23865 (60331) | 60331..60588 | - | 258 | WP_033807961.1 | conjugal transfer protein TrbE | - |
| F4V36_RS23870 (60615) | 60615..62519 | - | 1905 | WP_225620370.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| F4V36_RS23875 (62755) | 62755..63135 | - | 381 | WP_001462111.1 | hypothetical protein | - |
| F4V36_RS23880 (63132) | 63132..63770 | - | 639 | WP_033807960.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| F4V36_RS23885 (63779) | 63779..64084 | - | 306 | WP_000224418.1 | hypothetical protein | - |
| F4V36_RS23890 (64114) | 64114..65106 | - | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| F4V36_RS23895 (65103) | 65103..65735 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| F4V36_RS23900 (65732) | 65732..66118 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| F4V36_RS23905 (66115) | 66115..68745 | - | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| F4V36_RS23910 (68871) | 68871..69218 | - | 348 | WP_000836682.1 | hypothetical protein | - |
| F4V36_RS23915 (69246) | 69246..69464 | - | 219 | WP_033807959.1 | hypothetical protein | - |
| F4V36_RS23920 (69563) | 69563..70036 | - | 474 | WP_033807958.1 | hypothetical protein | - |
| F4V36_RS23925 (70029) | 70029..70442 | - | 414 | WP_000549589.1 | hypothetical protein | - |
| F4V36_RS23930 (70435) | 70435..70656 | - | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| F4V36_RS23935 (70791) | 70791..71306 | - | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| F4V36_RS23940 (71303) | 71303..71623 | - | 321 | WP_012881128.1 | conjugal transfer protein TrbD | - |
| F4V36_RS23945 (71610) | 71610..72200 | - | 591 | WP_000002784.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| F4V36_RS23950 (72190) | 72190..73617 | - | 1428 | WP_033807957.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| F4V36_RS23955 (73617) | 73617..74345 | - | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| F4V36_RS23960 (74332) | 74332..74898 | - | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| F4V36_RS23965 (74920) | 74920..75231 | - | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| F4V36_RS23970 (75246) | 75246..75605 | - | 360 | WP_001098994.1 | type IV conjugative transfer system pilin TraA | - |
| F4V36_RS23975 (75639) | 75639..75866 | - | 228 | WP_000589556.1 | conjugal transfer relaxosome protein TraY | - |
| F4V36_RS23980 (75986) | 75986..76633 | - | 648 | WP_000332523.1 | transcriptional regulator TraJ family protein | - |
| F4V36_RS23985 (76825) | 76825..77208 | - | 384 | WP_001151529.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| F4V36_RS23990 (77541) | 77541..78131 | + | 591 | WP_000252683.1 | hypothetical protein | VF |
| F4V36_RS23995 (78428) | 78428..79249 | - | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| F4V36_RS24000 (79360) | 79360..79656 | - | 297 | WP_001272251.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|