MGE detailed information
MGE type: Conjugative plasmid MGE length: 74819 bp
Accession: NZ_CP044149 Location: 1..74819 Organism: Escherichia coli O157 strain AR-0427 Replicon: plasmid pAR-0427-1
Accession: NZ_CP044149 Location: 1..74819 Organism: Escherichia coli O157 strain AR-0427 Replicon: plasmid pAR-0427-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F4V39_RS28225 () | 1..495 | - | 495 | WP_151142853.1 | DUF1281 domain-containing protein | - |
| F4V39_RS28235 () | 590..859 | - | 270 | WP_072126982.1 | hypothetical protein | - |
| F4V39_RS28240 () | 1030..1992 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| F4V39_RS28245 () | 1995..2345 | + | 351 | WP_001414994.1 | plasmid partitioning/stability family protein | - |
| F4V39_RS28250 () | 2454..2873 | + | 420 | WP_024181414.1 | hypothetical protein | - |
| F4V39_RS28255 () | 2808..3689 | - | 882 | WP_000005461.1 | hypothetical protein | - |
| F4V39_RS29625 () | 3760..3938 | - | 179 | Protein_6 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| F4V39_RS28265 () | 4162..4866 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| F4V39_RS28270 () | 4903..5559 | - | 657 | WP_000144779.1 | metallophosphoesterase | - |
| F4V39_RS28275 () | 5556..6065 | - | 510 | WP_000571065.1 | Dihydrofolate reductase | ARG |
| F4V39_RS28280 () | 6161..6865 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| F4V39_RS28285 () | 7156..8016 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| F4V39_RS28290 () | 8203..8532 | + | 330 | WP_001415369.1 | hypothetical protein | - |
| F4V39_RS28295 () | 8767..8988 | - | 222 | WP_001251694.1 | hypothetical protein | - |
| F4V39_RS28300 () | 8979..9182 | - | 204 | WP_000131876.1 | hypothetical protein | - |
| F4V39_RS28310 () | 9519..10334 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| F4V39_RS28315 () | 10395..11198 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| F4V39_RS28320 () | 11198..12034 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| F4V39_RS28330 () | 12340..12582 | + | 243 | WP_000844627.1 | transposase | - |
| F4V39_RS28335 () | 12614..13264 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| F4V39_RS28340 () | 13370..14569 | + | 1200 | WP_000804063.1 | Tetracycline resistance protein, class C | ARG |
| F4V39_RS28345 () | 14536..14724 | - | 189 | Protein_21 | IS91 family transposase | - |
| F4V39_RS28350 () | 14836..15141 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| F4V39_RS28355 () | 15169..16383 | - | 1215 | WP_023300759.1 | Bicyclomycin resistance protein | ARG |
| F4V39_RS29630 () | 16600..17046 | - | 447 | Protein_24 | DUF3363 domain-containing protein | - |
| F4V39_RS28365 () | 17515..19008 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| F4V39_RS28370 () | 19120..19500 | - | 381 | WP_001696636.1 | HTH domain-containing protein | - |
| F4V39_RS28380 () | 19941..20864 | - | 924 | WP_001415483.1 | hypothetical protein | - |
| F4V39_RS28385 () | 20912..21076 | - | 165 | WP_001388374.1 | hypothetical protein | Toxin Detail |
| F4V39_RS28390 () | 21073..21342 | - | 270 | WP_000079939.1 | hypothetical protein | Antitoxin Detail |
| F4V39_RS29445 () | 21415..21555 | - | 141 | WP_021503378.1 | hypothetical protein | - |
| F4V39_RS28400 () | 22257..23111 | - | 855 | Protein_31 | incFII family plasmid replication initiator RepA | - |
| F4V39_RS28405 () | 23104..23178 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| F4V39_RS28415 () | 23423..23670 | - | 248 | Protein_33 | replication regulatory protein RepA | - |
| F4V39_RS28420 () | 23910..24500 | - | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| F4V39_RS28425 () | 24538..24747 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| F4V39_RS28430 () | 24793..25254 | - | 462 | WP_000978819.1 | thermonuclease family protein | - |
| F4V39_RS28435 () | 25499..25711 | - | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| F4V39_RS28440 () | 25843..26403 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| F4V39_RS28445 () | 26458..27204 | - | 747 | WP_016230917.1 | conjugal transfer pilus acetylase TraX | - |
| F4V39_RS28450 () | 27224..32493 | - | 5270 | Protein_40 | Multifunctional conjugation protein TraI | Relaxase |
| F4V39_RS28455 () | 32493..34807 | - | 2315 | Protein_41 | Coupling protein TraD | VF |
| F4V39_RS28460 () | 34858..35595 | - | 738 | WP_021503363.1 | hypothetical protein | - |
| F4V39_RS28465 () | 35798..36529 | - | 732 | WP_021503382.1 | complement resistance protein TraT | - |
| F4V39_RS28470 () | 36561..37058 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| F4V39_RS28475 () | 37077..39895 | - | 2819 | Protein_45 | conjugal transfer mating pair stabilization protein TraG | - |
| F4V39_RS28480 () | 39892..41265 | - | 1374 | WP_001137361.1 | conjugal transfer protein TraH | - |
| F4V39_RS28485 () | 41252..41904 | - | 653 | Protein_47 | F-type conjugal transfer protein TrbF | - |
| F4V39_RS28495 () | 41894..42439 | - | 546 | WP_000059832.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| F4V39_RS28500 () | 42426..42710 | - | 285 | WP_000623730.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| F4V39_RS28505 () | 42837..43175 | - | 339 | WP_021503383.1 | conjugal transfer protein TrbA | - |
| F4V39_RS28510 () | 43191..43934 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| F4V39_RS28515 () | 43927..44184 | - | 258 | WP_000864319.1 | conjugal transfer protein TrbE | - |
| F4V39_RS28520 () | 44211..46061 | - | 1851 | WP_021503368.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| F4V39_RS28525 () | 46058..46696 | - | 639 | WP_001080257.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| F4V39_RS28530 () | 46705..47010 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| F4V39_RS28535 () | 47040..48032 | - | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| F4V39_RS28540 () | 48029..48661 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| F4V39_RS28545 () | 48658..49044 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| F4V39_RS28550 () | 49041..51671 | - | 2631 | WP_021503365.1 | type IV secretion system protein TraC | - |
| F4V39_RS28555 () | 51798..52145 | - | 348 | WP_000836682.1 | hypothetical protein | - |
| F4V39_RS28560 () | 52173..52391 | - | 219 | WP_016230909.1 | hypothetical protein | - |
| F4V39_RS28565 () | 52471..52944 | - | 474 | WP_021503376.1 | hypothetical protein | - |
| F4V39_RS28570 () | 52937..53350 | - | 414 | WP_021503371.1 | hypothetical protein | - |
| F4V39_RS28575 () | 53343..53564 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| F4V39_RS28580 () | 53699..54214 | - | 516 | WP_021503364.1 | type IV conjugative transfer system lipoprotein TraV | - |
| F4V39_RS28585 () | 54211..54462 | - | 252 | WP_021503369.1 | conjugal transfer protein TrbG | - |
| F4V39_RS28590 () | 54455..54823 | - | 369 | WP_071802386.1 | DUF2689 domain-containing protein | - |
| F4V39_RS28595 () | 54762..55349 | - | 588 | WP_023908347.1 | conjugal transfer protein TraP | - |
| F4V39_RS28600 () | 55318..56768 | - | 1451 | Protein_69 | conjugal transfer protein TraB | - |
| F4V39_RS28605 () | 56768..57496 | - | 729 | WP_001230809.1 | type-F conjugative transfer system secretin TraK | - |
| F4V39_RS28610 () | 57483..58049 | - | 567 | WP_021503373.1 | type IV conjugative transfer system protein TraE | - |
| F4V39_RS28615 () | 58071..58382 | - | 312 | WP_000012111.1 | type IV conjugative transfer system protein TraL | - |
| F4V39_RS28620 () | 58397..58756 | - | 360 | WP_019842162.1 | type IV conjugative transfer system pilin TraA | - |
| F4V39_RS28625 () | 58790..59017 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| F4V39_RS28630 () | 59111..59797 | - | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| F4V39_RS28635 () | 59991..60374 | - | 384 | WP_001151564.1 | relaxosome protein TraM | - |
| F4V39_RS28640 () | 60660..61307 | + | 648 | WP_072208664.1 | hypothetical protein | VF |
| F4V39_RS28645 () | 61603..62424 | - | 822 | WP_021503380.1 | DUF945 domain-containing protein | - |
| F4V39_RS28650 () | 62535..62831 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| F4V39_RS28660 () | 63131..63508 | + | 378 | Protein_80 | hypothetical protein | - |
| F4V39_RS28665 () | 63746..63904 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 63948..64172 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63948..64172 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63948..64172 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63948..64172 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| F4V39_RS28675 () | 64184..64903 | - | 720 | WP_033807739.1 | plasmid SOS inhibition protein A | - |
| F4V39_RS28680 () | 64900..65334 | - | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
| F4V39_RS28685 () | 65389..67347 | - | 1959 | WP_058653444.1 | ParB/RepB/Spo0J family partition protein | - |
| F4V39_RS28690 () | 67406..67639 | - | 234 | WP_058653442.1 | DUF905 domain-containing protein | - |
| F4V39_RS28695 () | 67695..68222 | - | 528 | WP_000290816.1 | single-stranded DNA-binding protein | - |
| F4V39_RS29450 () | 68567..68791 | + | 225 | WP_001380475.1 | hypothetical protein | - |
| F4V39_RS29455 () | 68695..68979 | - | 285 | WP_072165043.1 | hypothetical protein | - |
| F4V39_RS28720 () | 69131..69694 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| F4V39_RS28725 () | 69741..71102 | - | 1362 | WP_000170673.1 | DUF3560 domain-containing protein | - |
| F4V39_RS28730 () | 71154..71384 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| F4V39_RS29460 () | 71896..72144 | + | 249 | WP_071703862.1 | hypothetical protein | - |
| F4V39_RS28745 () | 72262..72885 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| F4V39_RS28750 () | 72967..74188 | + | 1222 | Protein_94 | tetracycline efflux MFS transporter Tet(B) | - |
| F4V39_RS28755 () | 74282..74819 | - | 538 | Protein_95 | TetR family transcriptional regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|