MGE detailed information
MGE type: Conjugative plasmid MGE length: 114358 bp
Accession: NZ_CP043824 Location: 1..114358 Organism: Escherichia coli strain RM10740 Replicon: plasmid p1RM10740
Accession: NZ_CP043824 Location: 1..114358 Organism: Escherichia coli strain RM10740 Replicon: plasmid p1RM10740
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F1748_RS25845 (1125) | 1125..2498 | - | 1374 | WP_001137358.1 | conjugal transfer pilus assembly protein TraH | - |
| F1748_RS25850 (2498) | 2498..2860 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| F1748_RS25855 (2790) | 2790..3335 | - | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| F1748_RS25860 (3322) | 3322..3606 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| F1748_RS25865 (3725) | 3725..4072 | - | 348 | WP_169001954.1 | conjugal transfer protein TrbA | - |
| F1748_RS25870 (4088) | 4088..4831 | - | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| F1748_RS25875 (4824) | 4824..5081 | - | 258 | WP_000864311.1 | conjugal transfer protein TrbE | - |
| F1748_RS25880 (5108) | 5108..6916 | - | 1809 | WP_000821818.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| F1748_RS25885 (6913) | 6913..7551 | - | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| F1748_RS25890 (7579) | 7579..8031 | - | 453 | WP_000069427.1 | hypothetical protein | - |
| F1748_RS25895 (8061) | 8061..8522 | - | 462 | WP_000277845.1 | hypothetical protein | - |
| F1748_RS25900 (8548) | 8548..9540 | - | 993 | WP_096094291.1 | conjugal transfer pilus assembly protein TraU | - |
| F1748_RS25905 (9537) | 9537..10169 | - | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| F1748_RS25910 (10166) | 10166..10552 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| F1748_RS25915 (10549) | 10549..13176 | - | 2628 | WP_097412077.1 | type IV secretion system protein TraC | - |
| F1748_RS25920 (13336) | 13336..13557 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| F1748_RS25925 (13692) | 13692..14207 | - | 516 | WP_000724020.1 | type IV conjugative transfer system lipoprotein TraV | - |
| F1748_RS25930 (14204) | 14204..14524 | - | 321 | WP_001057283.1 | conjugal transfer protein TrbD | - |
| F1748_RS25935 (14511) | 14511..15095 | - | 585 | WP_009424415.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| F1748_RS25940 (15085) | 15085..16512 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| F1748_RS25945 (16512) | 16512..17240 | - | 729 | WP_238005220.1 | type-F conjugative transfer system secretin TraK | - |
| F1748_RS25950 (17227) | 17227..17793 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| F1748_RS25955 (17815) | 17815..18126 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| F1748_RS25960 (18141) | 18141..18500 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| F1748_RS25965 (18534) | 18534..18761 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| F1748_RS25970 (18855) | 18855..19541 | - | 687 | WP_000332485.1 | PAS domain-containing protein | - |
| F1748_RS25975 (19732) | 19732..20115 | - | 384 | WP_000124976.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| F1748_RS25980 (20392) | 20392..21039 | + | 648 | WP_000614935.1 | hypothetical protein | VF |
| F1748_RS25985 (21336) | 21336..22157 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| F1748_RS25990 (22278) | 22278..22565 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| F1748_RS25995 (22590) | 22590..22796 | - | 207 | WP_000547971.1 | hypothetical protein | - |
| F1748_RS26000 (22866) | 22866..23039 | + | 174 | Protein_32 | hypothetical protein | - |
| F1748_RS26005 (23477) | 23477..23602 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| F1748_RS26010 (23544) | 23544..23693 | - | 150 | Protein_34 | plasmid maintenance protein Mok | - |
| - (23681) | 23681..23746 | - | 66 | NuclAT_1 | - | - |
| - (23679) | 23679..23903 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (23679) | 23679..23903 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (23679) | 23679..23903 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (23679) | 23679..23903 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (23679) | 23679..23903 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| F1748_RS26015 (23715) | 23715..23903 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| F1748_RS26020 (23872) | 23872..24634 | - | 763 | Protein_36 | plasmid SOS inhibition protein A | - |
| F1748_RS26025 (24631) | 24631..25065 | - | 435 | WP_089516080.1 | conjugation system SOS inhibitor PsiB | - |
| F1748_RS26030 (25120) | 25120..27078 | - | 1959 | WP_089516078.1 | ParB/RepB/Spo0J family partition protein | - |
| F1748_RS26035 (27140) | 27140..27373 | - | 234 | WP_000005974.1 | DUF905 domain-containing protein | - |
| F1748_RS26040 (27430) | 27430..27951 | - | 522 | WP_122986597.1 | single-stranded DNA-binding protein | - |
| F1748_RS26045 (28008) | 28008..28398 | + | 391 | Protein_41 | hypothetical protein | - |
| F1748_RS26050 (28484) | 28484..29047 | - | 564 | WP_089516070.1 | class I SAM-dependent methyltransferase | - |
| F1748_RS26055 (29094) | 29094..30455 | - | 1362 | WP_089516068.1 | DUF3560 domain-containing protein | - |
| F1748_RS26060 (30507) | 30507..30737 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| F1748_RS26065 (31254) | 31254..31502 | + | 249 | WP_071998823.1 | hypothetical protein | - |
| F1748_RS26070 (31774) | 31774..31965 | - | 192 | WP_001027514.1 | hypothetical protein | - |
| F1748_RS26075 (31962) | 31962..32384 | - | 423 | WP_063501347.1 | DUF1380 family protein | - |
| F1748_RS26080 (32431) | 32431..32856 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| F1748_RS26085 (33273) | 33273..34049 | - | 777 | WP_196037831.1 | hypothetical protein | - |
| F1748_RS26090 (34095) | 34095..34613 | - | 519 | WP_236475226.1 | DUF1380 family protein | - |
| F1748_RS26095 (34543) | 34543..34764 | - | 222 | WP_001104875.1 | hypothetical protein | - |
| F1748_RS26100 (34765) | 34765..35448 | - | 684 | WP_000086171.1 | DNA methylase | - |
| F1748_RS26105 (35524) | 35524..35829 | - | 306 | WP_089516096.1 | hypothetical protein | - |
| F1748_RS26110 (35965) | 35965..36927 | + | 963 | WP_000959875.1 | plasmid segregation protein ParM | - |
| F1748_RS26115 (36930) | 36930..37280 | + | 351 | WP_000361383.1 | plasmid partitioning/stability family protein | - |
| F1748_RS26120 (37396) | 37396..37500 | - | 105 | Protein_56 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| F1748_RS26125 (37771) | 37771..38610 | - | 840 | WP_071996207.1 | DUF4238 domain-containing protein | - |
| F1748_RS26130 (38896) | 38896..39654 | - | 759 | WP_001258298.1 | hypothetical protein | VF |
| F1748_RS26135 (39859) | 39859..40023 | + | 165 | Protein_59 | GNAT family N-acetyltransferase | - |
| F1748_RS26140 (40065) | 40065..40217 | - | 153 | Protein_60 | 3'-5' exonuclease | - |
| F1748_RS26145 (40327) | 40327..41349 | - | 1023 | WP_238005221.1 | hypothetical protein | - |
| F1748_RS26150 (41537) | 41537..42744 | + | 1208 | WP_089516347.1 | IS3 family transposase ISEc48 | Transposase |
| F1748_RS26155 (42741) | 42741..43775 | - | 1035 | WP_238005222.1 | hypothetical protein | - |
| F1748_RS26160 (43791) | 43791..44342 | - | 552 | WP_001749204.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| F1748_RS26165 (44579) | 44579..44716 | - | 138 | Protein_65 | IS6 family transposase | - |
| F1748_RS26170 (44779) | 44779..45483 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| F1748_RS26175 (45535) | 45535..46263 | + | 729 | Protein_67 | macrolide efflux MFS transporter Mef(B) | - |
| F1748_RS26180 (46409) | 46409..47272 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| F1748_RS26185 (47310) | 47310..47555 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| F1748_RS26190 (48024) | 48024..48815 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| F1748_RS26195 (48818) | 48818..49093 | - | 276 | WP_109023896.1 | hypothetical protein | - |
| F1748_RS26200 (49116) | 49116..49748 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| F1748_RS26205 (49995) | 49995..50195 | - | 201 | Protein_73 | SMR family transporter | - |
| F1748_RS26210 (50249) | 50249..50953 | - | 705 | WP_001067855.1 | Tn3 family transposase ISEc63 | Transposase |
| F1748_RS26215 (51017) | 51017..52321 | + | 1305 | Protein_75 | Tn3 family transposase ISEc63 | Transposase |
| F1748_RS26220 (52383) | 52383..53180 | - | 798 | WP_000544830.1 | IS21 family transposase IS21 | Transposase |
| F1748_RS26225 (53180) | 53180..54352 | - | 1173 | WP_089516343.1 | IS21 family transposase IS21 | Transposase |
| F1748_RS26230 (54454) | 54454..55968 | + | 1515 | Protein_78 | Tn3 family transposase ISEc63 | Transposase |
| F1748_RS26235 (56001) | 56001..56123 | - | 123 | Protein_79 | 3'-5' exonuclease | - |
| F1748_RS26240 (56159) | 56159..56437 | - | 279 | WP_001384452.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| F1748_RS26245 (56437) | 56437..56706 | - | 270 | WP_000079928.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| F1748_RS26250 (56820) | 56820..57601 | - | 782 | Protein_82 | IS21 family transposase IS100 | Transposase |
| F1748_RS26255 (57598) | 57598..57987 | - | 390 | Protein_83 | IS21 family transposase IS100kyp | Transposase |
| F1748_RS26260 (58076) | 58076..58477 | + | 402 | WP_000124097.1 | hypothetical protein | - |
| F1748_RS26265 (58440) | 58440..59627 | + | 1188 | WP_000937612.1 | IS91 family transposase IS91 | Transposase |
| F1748_RS26270 (59808) | 59808..60071 | - | 264 | WP_236411453.1 | DNA distortion polypeptide 3 | - |
| F1748_RS26275 (60208) | 60208..60654 | - | 447 | WP_000057426.1 | hypothetical protein | - |
| F1748_RS26280 (60694) | 60694..61530 | - | 837 | WP_001050931.1 | RepB family plasmid replication initiator protein | - |
| F1748_RS26285 (62764) | 62764..63015 | + | 252 | WP_000121743.1 | plasmid stabilization protein | - |
| F1748_RS26290 (63061) | 63061..63495 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| F1748_RS26295 (63567) | 63567..63917 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| F1748_RS26300 (63931) | 63931..64206 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| F1748_RS26305 (64242) | 64242..64664 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| F1748_RS26310 (64716) | 64716..66410 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| F1748_RS26315 (66428) | 66428..66790 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| F1748_RS26320 (66787) | 66787..67023 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| F1748_RS26325 (67020) | 67020..67172 | + | 153 | WP_238005214.1 | IS6 family transposase IS15 | Transposase |
| F1748_RS26330 (67184) | 67184..67921 | + | 738 | WP_238005215.1 | IS6 family transposase | - |
| F1748_RS26335 (67812) | 67812..68516 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| F1748_RS26340 (68581) | 68581..69015 | - | 435 | Protein_100 | IS91 family transposase IS91 | Transposase |
| F1748_RS26345 (68978) | 68978..69379 | - | 402 | WP_000124097.1 | hypothetical protein | - |
| F1748_RS26350 (70055) | 70055..70396 | - | 342 | Protein_102 | IS3 family transposase | - |
| F1748_RS26355 (70474) | 70474..71910 | - | 1437 | WP_000860466.1 | Hemolysin secretion protein D, plasmid | VF |
| F1748_RS26360 (71929) | 71929..74052 | - | 2124 | WP_000376539.1 | Alpha-hemolysin translocation ATP-binding protein HlyB | VF |
| F1748_RS26365 (74124) | 74124..77198 | - | 3075 | WP_000208152.1 | Hemolysin, plasmid | VF |
| F1748_RS26370 (77210) | 77210..77722 | - | 513 | WP_001372478.1 | Hemolysin-activating lysine-acyltransferase HlyC | VF |
| F1748_RS26380 (81130) | 81130..82317 | + | 1188 | WP_238005223.1 | IS91 family transposase ISEc37 | Transposase |
| F1748_RS26385 (82502) | 82502..82927 | - | 426 | Protein_109 | IS21 family transposase IS100kyp | Transposase |
| F1748_RS26390 (83044) | 83044..83184 | - | 141 | WP_162777809.1 | hypothetical protein | - |
| F1748_RS26395 (83886) | 83886..84743 | - | 858 | WP_000131006.1 | incFII family plasmid replication initiator RepA | - |
| F1748_RS26400 (84736) | 84736..84810 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| F1748_RS26405 (85047) | 85047..85301 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| F1748_RS26410 (85541) | 85541..86131 | - | 591 | WP_000766812.1 | DUF2726 domain-containing protein | - |
| F1748_RS26415 (86169) | 86169..86378 | - | 210 | WP_001302200.1 | hemolysin expression modulator Hha | - |
| F1748_RS26420 (86424) | 86424..86885 | - | 462 | WP_001233850.1 | thermonuclease family protein | - |
| F1748_RS26425 (87130) | 87130..87342 | - | 213 | WP_001302189.1 | ANR family transcriptional regulator | - |
| F1748_RS26430 (87464) | 87464..88141 | + | 678 | WP_238005217.1 | IS66 family transposase ISCro1 | Transposase |
| F1748_RS26435 (88141) | 88141..88488 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| F1748_RS26440 (88508) | 88508..90079 | + | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| F1748_RS26445 (90181) | 90181..90741 | - | 561 | WP_000840465.1 | fertility inhibition protein FinO | - |
| F1748_RS26450 (90844) | 90844..91704 | - | 861 | WP_000704525.1 | putative protein YcjY | VF |
| F1748_RS26455 (91830) | 91830..93581 | - | 1752 | Protein_123 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| F1748_RS26460 (93585) | 93585..93977 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| F1748_RS26465 (94115) | 94115..94999 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| F1748_RS26470 (95031) | 95031..96230 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| F1748_RS26475 (96336) | 96336..96986 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| F1748_RS26480 (97018) | 97018..97260 | - | 243 | WP_000844627.1 | transposase | - |
| F1748_RS26485 (97318) | 97318..100284 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| F1748_RS26490 (100288) | 100288..100848 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| F1748_RS26495 (101158) | 101158..102735 | + | 1578 | WP_001323889.1 | Aerotaxis receptor | VF |
| F1748_RS26500 (102869) | 102869..103642 | - | 774 | WP_097727424.1 | conjugal transfer pilus acetylase TraX | - |
| F1748_RS26505 (103662) | 103662..108932 | - | 5271 | WP_238005218.1 | Multifunctional conjugation protein TraI | Relaxase |
| F1748_RS26510 (108932) | 108932..111130 | - | 2199 | WP_011402783.1 | type IV conjugative transfer system coupling protein TraD | - |
| F1748_RS26515 (111383) | 111383..112114 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| F1748_RS26520 (112146) | 112146..112649 | - | 504 | WP_000605510.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|