MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 168626 bp
Accession: NZ_CP043485 Location: 1..168626 Organism: Enterococcus faecium strain DMEA02 Replicon: plasmid pDMEA1
Accession: NZ_CP043485 Location: 1..168626 Organism: Enterococcus faecium strain DMEA02 Replicon: plasmid pDMEA1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FZP47_RS12700 () | 898..2669 | - | 1772 | Protein_1 | AAA family ATPase | - |
| FZP47_RS12710 () | 2785..5933 | - | 3149 | Protein_2 | type I restriction endonuclease subunit R | - |
| FZP47_RS12715 () | 5947..7185 | - | 1239 | WP_149484507.1 | restriction endonuclease subunit S | - |
| FZP47_RS12720 () | 7175..8770 | - | 1596 | WP_010725625.1 | type I restriction-modification system subunit M | - |
| FZP47_RS12730 () | 9100..9678 | + | 579 | WP_002299133.1 | SinI family restriction endonuclease | - |
| FZP47_RS12740 () | 10150..11103 | + | 954 | WP_149484508.1 | IS30 family transposase IS1252 | Transposase |
| FZP47_RS12745 () | 11263..12540 | - | 1278 | WP_080481984.1 | S8 family serine peptidase | - |
| FZP47_RS12750 () | 12570..13298 | - | 729 | WP_002336727.1 | hypothetical protein | - |
| FZP47_RS12755 () | 13558..14106 | - | 549 | WP_002335394.1 | hypothetical protein | - |
| FZP47_RS12760 () | 14107..14964 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| FZP47_RS12765 () | 15250..15537 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FZP47_RS12770 () | 15527..15856 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| FZP47_RS12775 () | 15933..16205 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| FZP47_RS12780 () | 16205..16468 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| FZP47_RS12785 () | 16702..17610 | + | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| FZP47_RS12790 () | 17613..18788 | - | 1176 | WP_002336205.1 | MFS transporter | - |
| FZP47_RS12795 () | 18791..21040 | - | 2250 | WP_002314387.1 | alpha-galactosidase | - |
| FZP47_RS12800 () | 21137..21991 | - | 855 | WP_002338109.1 | AraC family transcriptional regulator | - |
| FZP47_RS12805 () | 22073..22981 | - | 909 | Protein_19 | IS982 family transposase ISEfm1 | Transposase |
| FZP47_RS12810 () | 23075..24010 | - | 936 | WP_002323400.1 | hypothetical protein | - |
| FZP47_RS12815 () | 24569..24886 | - | 318 | WP_002338111.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FZP47_RS12820 () | 24887..25141 | - | 255 | WP_002290397.1 | AbrB family transcriptional regulator | - |
| FZP47_RS12825 () | 25401..25619 | - | 219 | Protein_23 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FZP47_RS12830 () | 26179..26265 | - | 87 | Protein_24 | single-stranded DNA-binding protein | - |
| FZP47_RS12835 () | 27431..28471 | + | 1041 | WP_149484509.1 | replication initiator protein A | - |
| FZP47_RS12845 () | 28571..29741 | + | 1171 | Protein_26 | IS256 family transposase ISLgar5 | Transposase |
| FZP47_RS12850 () | 29850..30186 | - | 337 | Protein_27 | recombinase family protein | - |
| FZP47_RS12855 () | 30394..30591 | - | 198 | WP_002329849.1 | hypothetical protein | - |
| FZP47_RS12860 () | 30612..31124 | - | 513 | WP_149484510.1 | hypothetical protein | - |
| FZP47_RS12865 () | 31762..32025 | + | 264 | WP_002329851.1 | hypothetical protein | Antitoxin Detail |
| FZP47_RS12870 () | 32019..32369 | + | 351 | WP_002329852.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| FZP47_RS12875 () | 32393..32527 | - | 135 | Protein_32 | helix-turn-helix domain-containing protein | - |
| FZP47_RS12880 () | 32579..33163 | - | 585 | WP_149484511.1 | Tn3 family transposase TnBth3 | Transposase |
| FZP47_RS12885 () | 33404..33597 | + | 194 | Protein_34 | AbrB family transcriptional regulator | - |
| FZP47_RS12890 () | 33663..33788 | + | 126 | Protein_35 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| FZP47_RS12895 () | 33847..35178 | - | 1332 | WP_002329854.1 | helix-turn-helix domain-containing protein | - |
| FZP47_RS13735 () | 35879..36037 | - | 159 | WP_167818090.1 | hypothetical protein | - |
| FZP47_RS12900 () | 36504..37946 | - | 1443 | WP_002329855.1 | helix-turn-helix domain-containing protein | - |
| FZP47_RS12905 () | 38054..39118 | + | 1065 | WP_002329856.1 | DUF916 and DUF3324 domain-containing protein | - |
| FZP47_RS12910 () | 39712..42210 | + | 2499 | WP_149484512.1 | hypothetical protein | - |
| FZP47_RS12915 () | 42866..43717 | + | 852 | WP_002329858.1 | hypothetical protein | - |
| FZP47_RS12920 () | 43840..45150 | + | 1311 | WP_002329859.1 | DUF3440 domain-containing protein | - |
| FZP47_RS12925 () | 45132..45650 | + | 519 | WP_002329860.1 | ParB/RepB/Spo0J family partition protein | - |
| FZP47_RS12930 () | 45813..46592 | - | 780 | WP_002329861.1 | cyclase family protein | - |
| FZP47_RS12935 () | 46753..46848 | - | 96 | Protein_45 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FZP47_RS12940 () | 46865..47191 | - | 327 | Protein_46 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FZP47_RS12945 () | 47279..48283 | - | 1005 | WP_002329863.1 | DUF916 and DUF3324 domain-containing protein | - |
| FZP47_RS12950 () | 48844..49443 | - | 600 | Protein_48 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FZP47_RS12955 () | 49556..50923 | - | 1368 | WP_149484513.1 | lytic polysaccharide monooxygenase | - |
| FZP47_RS12960 () | 51304..51777 | - | 474 | WP_149484514.1 | hypothetical protein | - |
| FZP47_RS12965 () | 51998..52357 | - | 360 | WP_149029030.1 | BspA family leucine-rich repeat surface protein | - |
| FZP47_RS12970 () | 52685..52990 | - | 306 | WP_167818087.1 | LPXTG cell wall anchor domain-containing protein | - |
| FZP47_RS12975 () | 52965..53771 | - | 807 | WP_149029032.1 | WxL domain-containing protein | - |
| FZP47_RS12980 () | 54272..54853 | - | 582 | Protein_54 | Tn3 family transposase TnBth1 | Transposase |
| FZP47_RS12985 () | 55656..57329 | + | 1674 | WP_149484531.1 | type IA DNA topoisomerase | - |
| FZP47_RS13740 () | 57345..57494 | + | 150 | WP_167818086.1 | hypothetical protein | - |
| FZP47_RS12990 () | 57575..58171 | + | 597 | WP_149484516.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| FZP47_RS12995 () | 58184..59083 | + | 900 | WP_149484517.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| FZP47_RS13000 () | 59086..59571 | + | 486 | WP_149484518.1 | single-stranded DNA-binding protein | - |
| FZP47_RS13005 () | 59937..60197 | + | 261 | WP_149484519.1 | hypothetical protein | - |
| FZP47_RS13015 () | 60637..60843 | + | 207 | WP_053812808.1 | hypothetical protein | - |
| FZP47_RS13745 () | 60843..61001 | + | 159 | WP_167818085.1 | hypothetical protein | - |
| FZP47_RS13020 () | 61017..61454 | + | 438 | WP_149484520.1 | hypothetical protein | - |
| FZP47_RS13025 () | 61447..62154 | + | 708 | WP_149484521.1 | hypothetical protein | - |
| FZP47_RS13035 () | 62537..62716 | + | 180 | WP_002295613.1 | hypothetical protein | - |
| FZP47_RS13040 () | 62758..63120 | - | 363 | WP_002339845.1 | helix-turn-helix transcriptional regulator | - |
| FZP47_RS13045 () | 63244..64359 | + | 1116 | WP_002339846.1 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase | - |
| FZP47_RS13050 () | 64364..65197 | + | 834 | WP_002339847.1 | S-formylglutathione hydrolase | - |
| FZP47_RS13750 () | 65272..65685 | - | 414 | Protein_69 | IS1182 family transposase ISSmi2 | Transposase |
| FZP47_RS13060 () | 65845..66087 | - | 243 | Protein_70 | IS1380 family transposase IS1678 | Transposase |
| FZP47_RS13065 () | 66567..67715 | + | 1149 | WP_099036853.1 | glutathione-dependent formaldehyde dehydrogenase | - |
| FZP47_RS13070 () | 67832..68104 | - | 273 | Protein_72 | transposase | - |
| FZP47_RS13075 () | 68394..68861 | + | 468 | WP_099036855.1 | PTS sugar transporter subunit IIA | - |
| FZP47_RS13080 () | 68851..69132 | + | 282 | WP_002343698.1 | PTS sugar transporter subunit IIB | - |
| FZP47_RS13085 () | 69654..70265 | + | 612 | WP_099036851.1 | Arabinose 5-phosphate isomerase KdsD | VF |
| FZP47_RS13090 () | 70279..71181 | + | 903 | WP_099036850.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| FZP47_RS13095 () | 71184..71810 | + | 627 | WP_002343701.1 | bifunctional 2-keto-4-hydroxyglutarate aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase | - |
| FZP47_RS13100 () | 71835..73919 | + | 2085 | WP_099036848.1 | BglG family transcription antiterminator | - |
| FZP47_RS13105 () | 73916..74645 | + | 730 | Protein_79 | HAD family phosphatase | - |
| FZP47_RS13110 () | 75541..75735 | - | 195 | WP_128485747.1 | prolyl oligopeptidase family serine peptidase | - |
| FZP47_RS13115 () | 76297..77565 | - | 1269 | WP_099036847.1 | PTS transporter subunit IIC | - |
| FZP47_RS13120 () | 77588..77866 | - | 279 | WP_099036846.1 | PTS sugar transporter subunit IIB | - |
| FZP47_RS13125 () | 78690..80804 | + | 2115 | WP_149484523.1 | putative ATP-dependent Clp protease ATP-binding subunit | VF |
| FZP47_RS13130 () | 81181..82307 | + | 1127 | WP_139439753.1 | IS3 family transposase ISBce13 | Transposase |
| FZP47_RS13135 () | 82324..82920 | + | 597 | WP_002329890.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| FZP47_RS13140 () | 82917..84347 | - | 1431 | WP_002292444.1 | hypothetical protein | - |
| FZP47_RS13145 () | 84509..85693 | - | 1185 | WP_002329891.1 | IS256 family transposase ISEfm2 | Transposase |
| FZP47_RS13155 () | 86130..87089 | - | 960 | WP_002329140.1 | IS30 family transposase IS6770 | Transposase |
| FZP47_RS13170 () | 87983..88396 | - | 414 | WP_002292906.1 | Hsp20/alpha crystallin family protein | - |
| FZP47_RS13180 () | 89975..90517 | + | 543 | WP_100067862.1 | Lactococcin-G-processing and transport ATP-binding protein LagD | VF |
| FZP47_RS13185 () | 90577..90873 | + | 297 | WP_002293180.1 | bacteriocin immunity protein | - |
| FZP47_RS13190 () | 90932..92101 | - | 1170 | WP_002329896.1 | IS256 family transposase ISEfa13 | Transposase |
| FZP47_RS13195 () | 92692..93114 | + | 423 | WP_002307506.1 | cupin domain-containing protein | - |
| FZP47_RS13200 () | 93198..93851 | + | 654 | WP_002307505.1 | putative iron export ATP-binding protein FetA | VF |
| FZP47_RS13205 () | 93848..94612 | + | 765 | WP_002311027.1 | iron export ABC transporter permease subunit FetB | - |
| FZP47_RS13215 () | 95014..95256 | + | 243 | WP_002342366.1 | DUF302 domain-containing protein | - |
| FZP47_RS13225 () | 96640..97149 | + | 510 | WP_002295345.1 | hypothetical protein | - |
| FZP47_RS13230 () | 97600..98007 | - | 408 | WP_002329899.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| FZP47_RS13235 () | 98004..98237 | - | 234 | WP_002290351.1 | addiction module antitoxin | - |
| FZP47_RS13240 () | 98571..99656 | + | 1086 | WP_002290352.1 | tyrosine recombinase XerS | - |
| FZP47_RS13245 () | 99940..100605 | - | 666 | WP_002324528.1 | site-specific integrase | - |
| FZP47_RS13250 () | 100759..100908 | - | 150 | WP_002290356.1 | hypothetical protein | - |
| FZP47_RS13255 () | 100901..101110 | - | 210 | WP_002290357.1 | DUF3173 domain-containing protein | - |
| FZP47_RS13260 () | 101432..102538 | - | 1107 | Protein_106 | IS4 family transposase IS641 | Transposase |
| FZP47_RS13265 () | 102615..104075 | - | 1461 | WP_149484525.1 | sucrose phosphorylase | - |
| FZP47_RS13270 () | 104072..105292 | - | 1221 | WP_002342361.1 | hypothetical protein | - |
| FZP47_RS13275 () | 105353..107536 | - | 2184 | WP_002324534.1 | alpha-galactosidase | - |
| FZP47_RS13280 () | 107576..108406 | - | 831 | WP_002290368.1 | carbohydrate ABC transporter permease | - |
| FZP47_RS13285 () | 108418..109290 | - | 873 | WP_002290370.1 | sugar ABC transporter permease | - |
| FZP47_RS13290 () | 109300..110559 | - | 1260 | WP_002290371.1 | extracellular solute-binding protein | - |
| FZP47_RS13295 () | 110707..112017 | - | 1311 | WP_002341308.1 | alpha-glucosidase/alpha-galactosidase | - |
| FZP47_RS13300 () | 112049..112873 | - | 825 | WP_047929206.1 | carbohydrate ABC transporter permease | - |
| FZP47_RS13305 () | 112889..113785 | - | 897 | Protein_115 | sugar ABC transporter permease | - |
| FZP47_RS13310 () | 113868..115133 | - | 1266 | WP_149484526.1 | extracellular solute-binding protein | - |
| FZP47_RS13315 () | 115272..116297 | - | 1026 | WP_149484527.1 | LacI family DNA-binding transcriptional regulator | - |
| FZP47_RS13320 () | 116542..117813 | - | 1272 | WP_002290379.1 | substrate-binding domain-containing protein | - |
| FZP47_RS13325 () | 118097..119044 | - | 948 | WP_010728588.1 | VOC family protein | - |
| FZP47_RS13330 () | 119056..119529 | + | 474 | WP_002290382.1 | IS91 family transposase ISCARN110 | Transposase |
| FZP47_RS13335 () | 119702..120256 | - | 555 | WP_002290383.1 | tyrosine-type recombinase/integrase | - |
| FZP47_RS13340 () | 120726..120980 | - | 255 | Protein_122 | transposase | - |
| FZP47_RS13355 () | 122801..123055 | - | 255 | WP_149484528.1 | hypothetical protein | - |
| FZP47_RS13360 () | 123060..123416 | - | 357 | WP_002339153.1 | hypothetical protein | - |
| FZP47_RS13365 () | 123416..123808 | - | 393 | WP_002339152.1 | Tn3 family transposase TnpR_ISMex38 | Transposase |
| FZP47_RS13755 () | 124205..124502 | + | 298 | Protein_127 | transposase | - |
| FZP47_RS13375 () | 124619..126045 | + | 1427 | WP_087628212.1 | IS3 family transposase ISEfa10 | Transposase |
| FZP47_RS13380 () | 126340..127299 | - | 960 | WP_002329140.1 | IS30 family transposase IS6770 | Transposase |
| FZP47_RS13385 () | 127418..128380 | - | 963 | WP_002324511.1 | LacI family DNA-binding transcriptional regulator | - |
| FZP47_RS13390 () | 128382..129821 | - | 1440 | WP_047927837.1 | sucrose-6-phosphate hydrolase | - |
| FZP47_RS13395 () | 130006..131952 | + | 1947 | WP_128440554.1 | sucrose-specific PTS transporter subunit IIBC | - |
| FZP47_RS13400 () | 132216..133088 | + | 873 | WP_002292418.1 | ROK family protein | - |
| FZP47_RS13410 () | 133323..134704 | - | 1382 | Protein_134 | IS3 family transposase ISLca1 | Transposase |
| FZP47_RS13415 () | 135200..136153 | + | 954 | WP_002290567.1 | IS30 family transposase IS1252 | Transposase |
| FZP47_RS13420 () | 136434..137603 | - | 1170 | WP_128440555.1 | IS256 family transposase ISEfa13 | Transposase |
| FZP47_RS13425 () | 137823..139727 | - | 1905 | WP_047937348.1 | heavy metal translocating P-type ATPase | - |
| FZP47_RS13430 () | 139925..140158 | - | 234 | WP_002292161.1 | cation transporter | - |
| FZP47_RS13435 () | 140305..141160 | - | 856 | Protein_139 | prolipoprotein diacylglyceryl transferase | - |
| FZP47_RS13440 () | 141145..141483 | - | 339 | WP_060812727.1 | hypothetical protein | - |
| FZP47_RS13445 () | 141711..142415 | - | 705 | WP_123840449.1 | Crp/Fnr family transcriptional regulator | - |
| FZP47_RS13450 () | 142560..143132 | - | 573 | WP_128440556.1 | DNA protection during starvation protein | VF |
| FZP47_RS13455 () | 143668..144858 | - | 1191 | WP_128440557.1 | IS256 family transposase ISLgar5 | Transposase |
| FZP47_RS13465 () | 145330..146025 | + | 696 | WP_002325581.1 | histidinol phosphate phosphatase HisJ family protein | - |
| FZP47_RS13470 () | 146062..146559 | - | 498 | WP_002295755.1 | GNAT family N-acetyltransferase | - |
| FZP47_RS13475 () | 146615..147211 | - | 597 | Protein_146 | IS982 family transposase ISEfm1 | Transposase |
| FZP47_RS13480 () | 147358..147561 | - | 204 | WP_002377051.1 | hypothetical protein | VF |
| FZP47_RS13485 () | 147576..147965 | - | 390 | WP_002377053.1 | DUF3796 domain-containing protein | - |
| FZP47_RS13490 () | 147967..148962 | - | 996 | WP_002377055.1 | hypothetical protein | - |
| FZP47_RS13495 () | 148946..149629 | - | 684 | WP_002377057.1 | ABC transporter ATP-binding protein | - |
| FZP47_RS13760 () | 149638..149799 | - | 162 | WP_002377059.1 | hypothetical protein | - |
| FZP47_RS13500 () | 149929..150021 | - | 93 | Protein_152 | IS982 family transposase | - |
| FZP47_RS13510 () | 150215..151123 | + | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| FZP47_RS13515 () | 151143..151499 | - | 357 | Protein_154 | DUF2812 domain-containing protein | - |
| FZP47_RS13520 () | 151511..151822 | - | 312 | WP_002291321.1 | PadR family transcriptional regulator | - |
| FZP47_RS13765 () | 151889..152050 | + | 162 | WP_002291320.1 | hypothetical protein | - |
| FZP47_RS13530 () | 152371..153195 | - | 825 | WP_002291317.1 | endonuclease/exonuclease/phosphatase family protein | - |
| FZP47_RS13535 () | 153408..155570 | - | 2163 | WP_010725663.1 | PTS transporter subunit IIBC | - |
| FZP47_RS13540 () | 155851..158145 | + | 2295 | WP_002291308.1 | glycoside hydrolase family 65 protein | - |
| FZP47_RS13545 () | 158138..158803 | + | 666 | WP_002291307.1 | beta-phosphoglucomutase | - |
| FZP47_RS13550 () | 158796..159830 | + | 1035 | WP_002316717.1 | galactose mutarotase | - |
| FZP47_RS13555 () | 159899..160918 | + | 1020 | WP_002316718.1 | Catabolite control protein A | VF |
| FZP47_RS13565 () | 161222..161956 | - | 735 | WP_002329972.1 | hypothetical protein | - |
| FZP47_RS13570 () | 161995..163311 | - | 1317 | WP_033653686.1 | hypothetical protein | - |
| FZP47_RS13575 () | 163468..164148 | - | 681 | WP_149484529.1 | IS6 family transposase IS1297 | Transposase |
| FZP47_RS13585 () | 164194..164760 | + | 567 | WP_149484530.1 | dihydroxyacetone kinase subunit L | - |
| FZP47_RS13590 () | 165221..166519 | - | 1299 | WP_002290399.1 | polysaccharide deacetylase family protein | - |
| FZP47_RS13600 () | 166886..167794 | + | 909 | WP_010777190.1 | IS982 family transposase ISEfm1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|