NZ_CP0433451..128614

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 128614 bp
Accession: NZ_CP043345        Location: 1..128614         Organism: Klebsiella pneumoniae subsp. pneumoniae strain WCHKP020039       Replicon: plasmid pKPC2_020039


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVC44_RS26440 (1) 1..858 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
CVC44_RS26445 (1797) 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
CVC44_RS26450 (2543) 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
CVC44_RS26455 (2733) 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
CVC44_RS26460 (3383) 3383..3798 + 416 Protein_4 IS1-like element IS1B family transposase -
CVC44_RS26465 (3834) 3834..4379 - 546 Protein_5 Tn3 family transposase TnpA_Tn3 Transposase
CVC44_RS26470 (4445) 4445..5149 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26475 (5219) 5219..5410 + 192 Protein_7 IS1380 family transposase -
CVC44_RS26480 (5660) 5660..6535 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
CVC44_RS26485 (6570) 6570..7538 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
CVC44_RS26490 (7595) 7595..8692 + 1098 Protein_10 TonB-dependent receptor -
CVC44_RS26495 (8760) 8760..9236 - 477 Protein_11 PAS domain-containing protein -
CVC44_RS26500 (9289) 9289..9993 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26505 (10058) 10058..10648 + 591 Protein_13 IS91 family transposase ISSbo1 Transposase
CVC44_RS26510 (11104) 11104..11808 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26515 (11874) 11874..12392 + 519 WP_014839979.1 FidL-like protein -
CVC44_RS26520 (12397) 12397..12813 - 417 WP_014839980.1 Glutathione transferase FosA ARG
CVC44_RS26525 (13199) 13199..13903 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26530 (13954) 13954..14571 - 618 Protein_18 IS91 family transposase ISSbo1 Transposase
CVC44_RS26535 (14581) 14581..14769 - 189 WP_000957857.1 hypothetical protein -
CVC44_RS26540 (14861) 14861..15397 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
CVC44_RS26545 (15580) 15580..16440 + 861 WP_000027057.1 Beta-lactamase TEM ARG
CVC44_RS26550 (16610) 16610..17365 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
CVC44_RS26555 (17446) 17446..17760 - 315 Protein_23 hypothetical protein -
CVC44_RS26560 (17815) 17815..18519 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
CVC44_RS26565 (20099) 20099..20333 + 235 Protein_25 type II toxin-antitoxin system RelE/ParE family toxin -
CVC44_RS26570 (20461) 20461..20742 + 282 WP_001333089.1 hypothetical protein -
CVC44_RS26575 (20865) 20865..21215 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
CVC44_RS26580 (21218) 21218..22180 - 963 WP_000959884.1 plasmid segregation protein ParM -
CVC44_RS26585 (22327) 22327..22620 + 294 WP_032146011.1 hypothetical protein -
CVC44_RS26590 (22697) 22697..23380 + 684 WP_000085883.1 DNA methylase -
CVC44_RS26595 (23381) 23381..23602 + 222 WP_001104881.1 hypothetical protein -
CVC44_RS26600 (23616) 23616..24050 + 435 WP_000274503.1 DUF1380 family protein -
CVC44_RS26605 (24101) 24101..24877 + 777 WP_001383963.1 hypothetical protein -
CVC44_RS26610 (25295) 25295..25720 + 426 WP_001198928.1 antirestriction protein -
CVC44_RS26615 (25767) 25767..26189 + 423 WP_000271762.1 DUF1380 family protein -
CVC44_RS26620 (26186) 26186..26377 + 192 WP_001027493.1 hypothetical protein -
CVC44_RS26625 (26691) 26691..28358 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
CVC44_RS26630 (29087) 29087..29241 - 155 Protein_38 hypothetical protein -
CVC44_RS26635 (29758) 29758..29988 + 231 WP_000218642.1 hypothetical protein -
CVC44_RS26640 (30040) 30040..31401 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
CVC44_RS26645 (31448) 31448..32011 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
CVC44_RS26650 (32097) 32097..32552 - 456 Protein_42 hypothetical protein -
CVC44_RS26655 (32854) 32854..33381 + 528 WP_000290834.1 single-stranded DNA-binding protein -
CVC44_RS26660 (33439) 33439..33672 + 234 WP_000006003.1 DUF905 family protein -
CVC44_RS26665 (33733) 33733..35756 + 2024 Protein_45 ParB/RepB/Spo0J family partition protein -
CVC44_RS26670 (35825) 35825..36259 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
CVC44_RS26675 (36256) 36256..36975 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (36987) 36987..37211 + 225 NuclAT_0 - -
- (36987) 36987..37211 + 225 NuclAT_0 - -
- (36987) 36987..37211 + 225 NuclAT_0 - -
- (36987) 36987..37211 + 225 NuclAT_0 - -
CVC44_RS26680 (37197) 37197..37346 + 150 Protein_48 plasmid maintenance protein Mok -
CVC44_RS26685 (37288) 37288..37413 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
CVC44_RS26690 (37732) 37732..38028 - 297 Protein_50 hypothetical protein -
CVC44_RS26695 (38379) 38379..39083 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26700 (39146) 39146..39541 + 396 Protein_52 ATP-dependent endonuclease -
CVC44_RS26705 (39526) 39526..40548 + 1023 WP_000361404.1 helicase UvrD -
CVC44_RS26710 (40804) 40804..41501 + 698 WP_223174630.1 IS1 family transposase ISKpn14 Transposase
CVC44_RS26715 (41530) 41530..41802 + 273 Protein_55 transposase -
CVC44_RS26720 (42082) 42082..43086 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
CVC44_RS26725 (43165) 43165..43599 - 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
CVC44_RS26730 (43671) 43671..44021 + 351 WP_001294663.1 mercuric transport protein MerT -
CVC44_RS26735 (44035) 44035..44310 + 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
CVC44_RS26740 (44346) 44346..44768 + 423 WP_001340589.1 organomercurial transporter MerC -
CVC44_RS26745 (44820) 44820..46514 + 1695 WP_000105636.1 mercury(II) reductase -
CVC44_RS26750 (46532) 46532..46894 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
CVC44_RS26755 (46891) 46891..47127 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
CVC44_RS26760 (47163) 47163..47831 + 669 WP_001300294.1 putative signaling protein VF
CVC44_RS26765 (47906) 47906..49078 + 1173 Protein_65 transposase -
CVC44_RS26770 (49143) 49143..49847 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26775 (49899) 49899..50360 + 462 Protein_67 Tn3 family transposase TnpR_Tn3 Transposase
CVC44_RS26780 (50483) 50483..51463 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
CVC44_RS26785 (51739) 51739..52620 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
CVC44_RS26790 (52870) 52870..53751 - 882 Protein_70 IS1182 family transposase ISKpn6 Transposase
CVC44_RS26795 (53855) 53855..54151 - 297 WP_013213987.1 transcriptional regulator -
CVC44_RS26800 (54197) 54197..54352 - 156 WP_013213988.1 hypothetical protein -
CVC44_RS26805 (54480) 54480..54905 - 426 WP_013213989.1 antirestriction protein -
CVC44_RS26810 (55016) 55016..55294 - 279 WP_013213990.1 hypothetical protein -
CVC44_RS26815 (55828) 55828..56445 - 618 Protein_75 replication protein -
CVC44_RS26820 (56837) 56837..57397 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
CVC44_RS26825 (57401) 57401..59689 + 2289 Protein_77 Tn3 family transposase TnpA_TnAs1 Transposase
CVC44_RS26830 (59743) 59743..60447 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26835 (60513) 60513..60797 + 285 Protein_79 PAS domain-containing protein -
CVC44_RS26840 (60861) 60861..61565 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26845 (61619) 61619..61942 - 324 Protein_81 class II aldolase/adducin family protein -
CVC44_RS26850 (61935) 61935..63187 - 1253 Protein_82 four-carbon acid sugar kinase family protein -
CVC44_RS26855 (63199) 63199..64101 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
CVC44_RS26860 (64363) 64363..65124 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
CVC44_RS26865 (65145) 65145..66005 - 861 WP_002904004.1 Beta-lactamase SHV-2 ARG
CVC44_RS26870 (66142) 66142..66210 + 69 Protein_86 IS6 family transposase -
CVC44_RS26875 (66246) 66246..66929 - 684 Protein_87 Tn3 family transposase TnpA_TnAs1 Transposase
CVC44_RS26880 (66994) 66994..67698 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS26885 (67748) 67748..68926 - 1179 Protein_89 AAA family ATPase -
CVC44_RS26890 (69000) 69000..69416 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
CVC44_RS26895 (69413) 69413..69643 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
CVC44_RS26900 (69600) 69600..70061 + 462 WP_014343465.1 hypothetical protein -
CVC44_RS26905 (70222) 70222..71166 + 945 WP_011977810.1 hypothetical protein -
CVC44_RS26910 (71203) 71203..71595 + 393 WP_011977811.1 hypothetical protein -
CVC44_RS26915 (71653) 71653..72174 + 522 WP_013214008.1 hypothetical protein -
CVC44_RS26920 (72220) 72220..72423 + 204 WP_011977813.1 hypothetical protein -
CVC44_RS26925 (72453) 72453..73457 + 1005 WP_011977814.1 hypothetical protein -
CVC44_RS26930 (73641) 73641..74420 + 780 WP_013214009.1 site-specific integrase -
CVC44_RS26935 (74466) 74466..74723 - 258 WP_013214010.1 hypothetical protein -
CVC44_RS26940 (74852) 74852..74965 - 114 WP_014343462.1 hypothetical protein -
CVC44_RS26945 (75501) 75501..76367 + 867 WP_004118283.1 replication initiation protein -
CVC44_RS26950 (77477) 77477..78682 + 1206 WP_011977818.1 AAA family ATPase -
CVC44_RS26955 (78682) 78682..79656 + 975 WP_011977819.1 ParB family protein -
CVC44_RS26960 (79738) 79738..81009 - 1272 WP_013214011.1 Y-family DNA polymerase -
CVC44_RS26965 (81009) 81009..81440 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
CVC44_RS26970 (81847) 81847..83334 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
CVC44_RS26975 (83583) 83583..84554 + 972 WP_004152353.1 plasmid segregation protein ParM -
CVC44_RS26980 (84557) 84557..85228 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
CVC44_RS26985 (85291) 85291..85521 + 231 WP_001568040.1 hypothetical protein -
CVC44_RS26990 (85717) 85717..85886 + 170 Protein_110 hypothetical protein -
CVC44_RS26995 (85958) 85958..86659 + 702 WP_001568041.1 DNA methylase -
CVC44_RS27000 (86659) 86659..86880 + 222 WP_001568042.1 hypothetical protein -
CVC44_RS27005 (86890) 86890..87309 + 420 WP_001568043.1 DUF1380 domain-containing protein -
CVC44_RS27010 (87363) 87363..88130 + 768 WP_013214013.1 hypothetical protein -
CVC44_RS27015 (88811) 88811..89239 + 429 WP_001568045.1 antirestriction protein -
CVC44_RS27020 (89282) 89282..89788 + 507 WP_013214014.1 antirestriction protein ArdA -
CVC44_RS27025 (89831) 89831..90022 + 192 WP_001568047.1 hypothetical protein -
CVC44_RS27030 (90210) 90210..90464 + 255 WP_011977779.1 DNA polymerase III subunit theta -
CVC44_RS27035 (90499) 90499..90819 + 321 WP_001568049.1 hypothetical protein -
CVC44_RS27040 (91499) 91499..91726 + 228 WP_001568050.1 hypothetical protein -
CVC44_RS27045 (91818) 91818..92048 + 231 WP_001568051.1 hypothetical protein -
CVC44_RS27050 (92100) 92100..93455 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
CVC44_RS27055 (93503) 93503..94066 + 564 WP_014343514.1 methyltransferase -
CVC44_RS27060 (94899) 94899..95441 + 543 WP_014343512.1 single-stranded DNA-binding protein -
CVC44_RS27065 (95490) 95490..95738 + 249 WP_001568055.1 DUF905 domain-containing protein -
CVC44_RS27070 (95808) 95808..97865 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
CVC44_RS27075 (97910) 97910..98341 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
CVC44_RS27080 (98338) 98338..99066 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
CVC44_RS27085 (99063) 99063..99389 + 327 WP_013023807.1 hypothetical protein -
CVC44_RS27090 (99445) 99445..99819 + 375 WP_014343510.1 hypothetical protein -
CVC44_RS27095 (99989) 99989..100141 + 153 WP_004150508.1 DUF5431 family protein -
CVC44_RS27100 (100086) 100086..100205 + 120 WP_159376494.1 type I toxin-antitoxin system Hok family toxin -
CVC44_RS27105 (100898) 100898..101170 + 273 WP_040245921.1 hypothetical protein -
CVC44_RS27110 (101167) 101167..101517 + 351 WP_040245917.1 hypothetical protein -
CVC44_RS27115 (101532) 101532..101849 + 318 WP_014343505.1 hypothetical protein -
CVC44_RS27120 (102720) 102720..103424 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS27125 (103477) 103477..103542 + 66 Protein_137 helix-turn-helix domain-containing protein -
CVC44_RS27130 (103545) 103545..106511 + 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
CVC44_RS27135 (106590) 106590..107594 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
CVC44_RS27140 (107866) 107866..107952 - 87 Protein_140 Arm DNA-binding domain-containing protein -
CVC44_RS27145 (108074) 108074..108298 - 225 WP_000743213.1 hypothetical protein -
CVC44_RS27150 (108295) 108295..109032 - 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
CVC44_RS27155 (109518) 109518..109658 - 141 WP_001044210.1 hypothetical protein -
CVC44_RS27160 (109664) 109664..110368 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS27165 (110837) 110837..111400 - 564 WP_155082050.1 hypothetical protein -
CVC44_RS27170 (111522) 111522..112064 - 543 WP_077273850.1 restriction endonuclease -
CVC44_RS27175 (112046) 112046..113026 - 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
CVC44_RS27180 (113095) 113095..113487 + 393 Protein_148 3'-5' exonuclease -
CVC44_RS27185 (113540) 113540..113935 + 396 WP_015493087.1 hypothetical protein -
CVC44_RS27190 (113932) 113932..114543 + 612 WP_015493086.1 DUF2913 family protein -
CVC44_RS27195 (114540) 114540..115490 - 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
CVC44_RS27200 (115819) 115819..116523 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS27205 (116557) 116557..116904 - 348 WP_094623447.1 type IV conjugative transfer system pilin TraA -
CVC44_RS27210 (116966) 116966..117172 - 207 WP_171773970.1 TraY domain-containing protein -
CVC44_RS27215 (117287) 117287..118024 - 738 WP_013214018.1 conjugal transfer protein TrbJ -
CVC44_RS27220 (118224) 118224..118640 - 417 WP_014343494.1 conjugal transfer relaxosome DNA-binding protein TraM -
CVC44_RS27225 (119031) 119031..119516 + 486 WP_014343495.1 hypothetical protein VF
CVC44_RS27230 (119549) 119549..119878 - 330 WP_013214015.1 DUF5983 family protein -
CVC44_RS27235 (119911) 119911..120732 - 822 WP_004152492.1 DUF932 domain-containing protein -
CVC44_RS27240 (121561) 121561..121665 - 105 Protein_160 transcriptional regulator -
CVC44_RS27245 (121669) 121669..121947 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
CVC44_RS27250 (121937) 121937..122257 - 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
CVC44_RS27255 (122338) 122338..122562 - 225 WP_014343499.1 hypothetical protein -
CVC44_RS27260 (122573) 122573..122785 - 213 WP_014343500.1 hypothetical protein -
CVC44_RS27265 (122846) 122846..123202 - 357 WP_014343501.1 hypothetical protein -
CVC44_RS27270 (123296) 123296..124000 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CVC44_RS27275 (124025) 124025..124225 + 201 WP_072354025.1 hypothetical protein -
CVC44_RS27280 (124245) 124245..124991 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
CVC44_RS27285 (125046) 125046..125606 + 561 WP_000139328.1 fertility inhibition protein FinO -
CVC44_RS27290 (125738) 125738..125938 + 201 WP_015059022.1 hypothetical protein -
CVC44_RS27295 (126324) 126324..126923 + 600 WP_032083981.1 PIN domain-containing protein -
CVC44_RS27300 (126985) 126985..127317 + 333 WP_152916585.1 hypothetical protein -
- (127518) 127518..127577 - 60 NuclAT_1 - Antitoxin Detail
- (127518) 127518..127577 - 60 NuclAT_1 - Antitoxin Detail
- (127518) 127518..127577 - 60 NuclAT_1 - Antitoxin Detail
- (127518) 127518..127577 - 60 NuclAT_1 - Antitoxin Detail
CVC44_RS27305 (127622) 127622..127771 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
CVC44_RS27310 (128055) 128055..128303 + 249 WP_000083837.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance