MGE detailed information
MGE type: Conjugative plasmid MGE length: 139547 bp
Accession: NZ_CP041393 Location: 1..139547 Organism: Escherichia coli strain ECOL-18-VL-LA-PA-Ryan-0026 Replicon: plasmid p45407_1
Accession: NZ_CP041393 Location: 1..139547 Organism: Escherichia coli strain ECOL-18-VL-LA-PA-Ryan-0026 Replicon: plasmid p45407_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E3Z24_RS23435 () | 530..634 | - | 105 | Protein_1 | thiosulfate reductase cytochrome B subunit | - |
| E3Z24_RS23440 () | 691..1384 | + | 694 | Protein_2 | IS1 family transposase IS1A | Transposase |
| E3Z24_RS23445 () | 1400..2023 | + | 624 | WP_000912556.1 | potassium channel family protein | - |
| E3Z24_RS23450 () | 2108..2359 | + | 252 | Protein_4 | iron-containing alcohol dehydrogenase | - |
| E3Z24_RS23455 () | 2648..2965 | - | 318 | Protein_5 | IS110 family transposase | - |
| E3Z24_RS23460 () | 3120..3225 | + | 106 | Protein_6 | plasmid SOS inhibition protein A | - |
| - () | 3194..3392 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 3194..3392 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 3194..3392 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 3194..3392 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| E3Z24_RS23465 () | 3457..3615 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| E3Z24_RS25390 () | 4283..4489 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| E3Z24_RS23475 () | 4514..4801 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| E3Z24_RS23480 () | 4920..5741 | + | 822 | WP_001234465.1 | DUF945 domain-containing protein | - |
| E3Z24_RS23485 () | 6037..6609 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
| E3Z24_RS23490 () | 6979..7362 | + | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| E3Z24_RS23495 () | 7553..8200 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| E3Z24_RS23500 () | 8336..8551 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| E3Z24_RS23505 () | 8594..8959 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| E3Z24_RS23510 () | 8974..9285 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| E3Z24_RS23515 () | 9307..9873 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| E3Z24_RS23520 () | 9884..10588 | + | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| E3Z24_RS23525 () | 10588..12015 | + | 1428 | WP_001553836.1 | conjugal transfer protein TraB | - |
| E3Z24_RS23530 () | 12005..12595 | + | 591 | WP_087523585.1 | conjugal transfer protein TraP | - |
| E3Z24_RS23535 () | 12582..12719 | + | 138 | WP_001553834.1 | conjugal transfer protein TrbD | - |
| E3Z24_RS23540 () | 12741..12902 | + | 162 | WP_000741714.1 | conjugal transfer protein TrbD | - |
| E3Z24_RS23545 () | 12895..13146 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| E3Z24_RS23550 () | 13143..13658 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| E3Z24_RS23555 () | 13793..14014 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| E3Z24_RS23560 () | 14174..16801 | + | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| E3Z24_RS23565 () | 16798..17184 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| E3Z24_RS23570 () | 17181..17813 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| E3Z24_RS23575 () | 17810..18802 | + | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| E3Z24_RS23580 () | 18811..19449 | + | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| E3Z24_RS23585 () | 19446..21254 | + | 1809 | WP_039023153.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| E3Z24_RS23590 () | 21281..21538 | + | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| E3Z24_RS23595 () | 21531..22274 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| E3Z24_RS23600 () | 22290..22637 | + | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| E3Z24_RS23605 () | 22756..23040 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| E3Z24_RS23610 () | 23027..23572 | + | 546 | WP_016236310.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| E3Z24_RS23615 () | 23502..23864 | + | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| E3Z24_RS23620 () | 23864..25237 | + | 1374 | WP_039023150.1 | conjugal transfer protein TraH | - |
| E3Z24_RS23625 () | 25234..28053 | + | 2820 | WP_039023149.1 | conjugal transfer mating pair stabilization protein TraG | - |
| E3Z24_RS23630 () | 28072..28569 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| E3Z24_RS23635 () | 28601..29332 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| E3Z24_RS23640 () | 29585..31810 | + | 2226 | WP_106493937.1 | type IV conjugative transfer system coupling protein TraD | - |
| E3Z24_RS23645 () | 31819..32217 | - | 399 | WP_039023147.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| E3Z24_RS23650 () | 32217..32444 | - | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| E3Z24_RS23655 () | 32526..37796 | + | 5271 | WP_039023145.1 | Multifunctional conjugation protein TraI | Relaxase |
| E3Z24_RS23665 () | 38072..39613 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| E3Z24_RS23670 () | 39628..40374 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| E3Z24_RS23675 () | 40402..41148 | + | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| E3Z24_RS23680 () | 41203..41763 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| E3Z24_RS23685 () | 41894..42103 | + | 210 | WP_039023209.1 | hypothetical protein | - |
| E3Z24_RS23690 () | 42515..43141 | + | 627 | WP_029702149.1 | hypothetical protein | - |
| E3Z24_RS23695 () | 43293..43862 | + | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| E3Z24_RS25395 () | 44237..44503 | + | 267 | WP_087757657.1 | hypothetical protein | - |
| - () | 44642..44703 | - | 62 | NuclAT_1 | - | - |
| - () | 44642..44703 | - | 62 | NuclAT_1 | - | - |
| - () | 44642..44703 | - | 62 | NuclAT_1 | - | - |
| - () | 44642..44703 | - | 62 | NuclAT_1 | - | - |
| E3Z24_RS23710 () | 44690..44896 | + | 207 | WP_032215358.1 | type I toxin-antitoxin system Hok family toxin | - |
| E3Z24_RS23715 () | 45180..45437 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| E3Z24_RS23725 () | 45673..45747 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| E3Z24_RS23730 () | 45740..46597 | + | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| E3Z24_RS23740 () | 47536..48189 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| E3Z24_RS23745 () | 48282..48539 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| E3Z24_RS23750 () | 48472..48873 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| E3Z24_RS23755 () | 49010..51907 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| E3Z24_RS23760 () | 52002..52607 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| E3Z24_RS23765 () | 52631..53380 | - | 750 | Protein_63 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| E3Z24_RS23770 () | 53369..53776 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| E3Z24_RS23775 () | 53914..54798 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| E3Z24_RS23780 () | 54830..56029 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| E3Z24_RS23785 () | 56135..56785 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| E3Z24_RS23790 () | 56817..57059 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| E3Z24_RS23795 () | 57101..58615 | - | 1515 | Protein_69 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| E3Z24_RS23800 () | 58681..59385 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E3Z24_RS23805 () | 59529..60083 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| E3Z24_RS23810 () | 60214..61044 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| E3Z24_RS23815 () | 61182..61622 | + | 441 | Protein_73 | CatB-related O-acetyltransferase | - |
| E3Z24_RS23820 () | 61676..62380 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E3Z24_RS23825 () | 62446..62733 | + | 288 | Protein_75 | IS1380 family transposase ISEcp1 | Transposase |
| E3Z24_RS23830 () | 62989..63864 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| E3Z24_RS23835 () | 63911..64243 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| E3Z24_RS23840 () | 64257..66500 | + | 2244 | Protein_78 | Tn3 family transposase TnpA_Tn3 | Transposase |
| E3Z24_RS23845 () | 66565..67269 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E3Z24_RS25400 () | 67322..67570 | - | 249 | Protein_80 | DUF3330 domain-containing protein | - |
| E3Z24_RS23855 () | 67773..68786 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| E3Z24_RS23860 () | 68944..69417 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| E3Z24_RS23865 () | 69548..70336 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| E3Z24_RS23870 () | 70542..70889 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| E3Z24_RS23875 () | 70883..71722 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| E3Z24_RS23880 () | 72127..73668 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| E3Z24_RS23890 () | 73981..75012 | + | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| E3Z24_RS23895 () | 75023..75661 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| E3Z24_RS23900 () | 75666..76031 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| E3Z24_RS23905 () | 76035..76847 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| E3Z24_RS23910 () | 76948..77241 | - | 294 | Protein_91 | IS30 family transposase | - |
| E3Z24_RS23915 () | 77406..78110 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E3Z24_RS23920 () | 78165..79031 | - | 867 | Protein_93 | IS91 family transposase ISAzo26 | Transposase |
| E3Z24_RS23925 () | 79176..79673 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| E3Z24_RS23930 () | 79785..80075 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| E3Z24_RS23935 () | 80081..80872 | + | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| E3Z24_RS23940 () | 81036..81383 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| E3Z24_RS23945 () | 81377..82216 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| E3Z24_RS23955 () | 82344..82547 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| E3Z24_RS23960 () | 82703..83908 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| E3Z24_RS23965 () | 83919..84224 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| E3Z24_RS25405 () | 84268..84333 | + | 66 | Protein_102 | EAL domain-containing protein | - |
| E3Z24_RS23975 () | 84451..85215 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| E3Z24_RS23990 () | 85708..86292 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| E3Z24_RS23995 () | 86292..87530 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| E3Z24_RS24000 () | 87527..88432 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| E3Z24_RS24010 () | 88554..89258 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E3Z24_RS24015 () | 89316..91730 | + | 2415 | Protein_108 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| E3Z24_RS24020 () | 91764..91868 | + | 105 | Protein_109 | IS5/IS1182 family transposase | - |
| E3Z24_RS24025 () | 92018..92650 | - | 633 | Protein_110 | histidine-type phosphatase | - |
| E3Z24_RS24030 () | 92772..93257 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| E3Z24_RS24035 () | 93282..93767 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| E3Z24_RS24040 () | 93754..94449 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| E3Z24_RS24045 () | 94454..95584 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
| E3Z24_RS24050 () | 95574..96857 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| E3Z24_RS24055 () | 96860..98239 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| E3Z24_RS24060 () | 98343..98870 | - | 528 | WP_000178050.1 | iron transporter | - |
| E3Z24_RS24065 () | 98911..100797 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| E3Z24_RS24075 () | 101144..101959 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| E3Z24_RS24080 () | 102142..102648 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| E3Z24_RS24085 () | 102638..102796 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| E3Z24_RS25450 () | 102946..103059 | - | 114 | Protein_122 | IS6 family transposase | - |
| E3Z24_RS24100 () | 103259..103956 | + | 698 | Protein_123 | IS1 family transposase IS1X2 | Transposase |
| E3Z24_RS24105 () | 104106..104792 | + | 687 | Protein_124 | IS1 family transposase IS1S | Transposase |
| E3Z24_RS24110 () | 105046..106068 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| E3Z24_RS24115 () | 106053..107618 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| E3Z24_RS24120 () | 107693..108109 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| E3Z24_RS24125 () | 108106..108336 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| E3Z24_RS24135 () | 108896..109114 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| E3Z24_RS24140 () | 109116..109421 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| E3Z24_RS24145 () | 109422..110228 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| E3Z24_RS24150 () | 110950..111705 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| E3Z24_RS24155 () | 112293..113459 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| E3Z24_RS24160 () | 113459..114430 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| E3Z24_RS24170 () | 115168..116070 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| E3Z24_RS24175 () | 116074..116378 | + | 305 | Protein_136 | hypothetical protein | - |
| E3Z24_RS24180 () | 116455..117138 | + | 684 | WP_032181561.1 | DNA methylase | - |
| E3Z24_RS24185 () | 117139..117360 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| E3Z24_RS24190 () | 117374..117808 | + | 435 | WP_001546462.1 | DUF1380 family protein | - |
| E3Z24_RS24195 () | 117853..118623 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| E3Z24_RS24205 () | 119160..119462 | + | 303 | WP_001666994.1 | antirestriction protein | - |
| E3Z24_RS24210 () | 119509..119931 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| E3Z24_RS24215 () | 119928..120119 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| E3Z24_RS24225 () | 120432..122099 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| E3Z24_RS25410 () | 122734..122982 | - | 249 | WP_071781657.1 | hypothetical protein | - |
| E3Z24_RS24235 () | 123499..123729 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| E3Z24_RS24240 () | 123781..125142 | + | 1362 | WP_039023242.1 | DUF3560 domain-containing protein | - |
| E3Z24_RS24245 () | 125190..125753 | + | 564 | WP_029702196.1 | class I SAM-dependent methyltransferase | - |
| E3Z24_RS24255 () | 126122..127789 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| E3Z24_RS24275 () | 129451..130020 | - | 570 | WP_089634947.1 | hypothetical protein | - |
| E3Z24_RS24285 () | 131324..132082 | + | 759 | Protein_152 | site-specific integrase | - |
| E3Z24_RS24290 () | 132240..133250 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| E3Z24_RS24295 () | 133346..135472 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| E3Z24_RS24300 () | 135535..136812 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| E3Z24_RS24305 () | 136809..138242 | + | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|