MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 126409 bp
Accession: NZ_CP041032 Location: 1..126409 Organism: Escherichia coli strain PT109 Replicon: plasmid pLB_CTX-M-15_PT109
Accession: NZ_CP041032 Location: 1..126409 Organism: Escherichia coli strain PT109 Replicon: plasmid pLB_CTX-M-15_PT109
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FIR93_RS23190 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| FIR93_RS23195 () | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| FIR93_RS23200 () | 2124..2312 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| FIR93_RS23205 () | 2679..3848 | + | 1170 | WP_137497552.1 | hypothetical protein | - |
| FIR93_RS23210 () | 4074..4249 | - | 176 | Protein_4 | IS3 family transposase | - |
| FIR93_RS23215 () | 4695..4967 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| FIR93_RS23220 () | 5492..5928 | - | 437 | Protein_6 | IS3 family transposase IS2 | Transposase |
| FIR93_RS23225 () | 6210..8180 | + | 1971 | WP_001496335.1 | Hemin receptor | VF |
| FIR93_RS23230 () | 8187..8978 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| FIR93_RS23235 () | 9041..9649 | - | 609 | Protein_9 | IS66 family transposase ISEc22 | Transposase |
| FIR93_RS23240 () | 9717..10496 | - | 780 | WP_001297096.1 | IS21 family transposase IS100kyp | Transposase |
| FIR93_RS23245 () | 10496..11518 | - | 1023 | WP_000255956.1 | IS21 family transposase IS100kyp | Transposase |
| FIR93_RS23250 () | 11604..12549 | - | 946 | Protein_12 | IS66 family transposase ISEc8 | Transposase |
| FIR93_RS23255 () | 12598..12972 | - | 375 | WP_024193849.1 | IS66 family transposase ISKpn24 | Transposase |
| FIR93_RS23260 () | 12997..13701 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FIR93_RS23265 () | 13823..14728 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| FIR93_RS23270 () | 14725..15963 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| FIR93_RS23275 () | 15963..16547 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| FIR93_RS23280 () | 17040..17804 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| FIR93_RS24380 () | 17922..17987 | - | 66 | Protein_19 | EAL domain-containing protein | - |
| FIR93_RS23285 () | 18031..18336 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| FIR93_RS23290 () | 18347..19552 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| FIR93_RS23295 () | 19708..19911 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| FIR93_RS23300 () | 20039..20878 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| FIR93_RS23305 () | 20872..21219 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| FIR93_RS23310 () | 21425..22213 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| FIR93_RS23315 () | 22344..22817 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| FIR93_RS23320 () | 22975..23988 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| FIR93_RS23325 () | 24191..24541 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| FIR93_RS23330 () | 24667..24810 | + | 144 | Protein_29 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| FIR93_RS23335 () | 24855..25559 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FIR93_RS23340 () | 25628..26032 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| FIR93_RS23345 () | 26112..27184 | - | 1073 | Protein_32 | IS3 family transposase IS629 | Transposase |
| FIR93_RS23350 () | 27286..27546 | + | 261 | WP_000371882.1 | hypothetical protein | - |
| FIR93_RS23355 () | 27543..28112 | + | 570 | WP_000194541.1 | hypothetical protein | - |
| FIR93_RS23360 () | 28132..28479 | - | 348 | WP_000142452.1 | hypothetical protein | - |
| FIR93_RS23365 () | 28608..28943 | + | 336 | WP_001080732.1 | colicin transporter | - |
| FIR93_RS23370 () | 30395..31081 | + | 687 | Protein_37 | replication initiation protein | - |
| FIR93_RS23375 () | 31413..32288 | + | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| FIR93_RS23380 () | 32296..33072 | + | 777 | WP_000981091.1 | energy transducer TonB | - |
| FIR93_RS23385 () | 33241..35502 | + | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| FIR93_RS23390 () | 35571..36746 | + | 1176 | WP_001020413.1 | putative protein YncE | VF |
| FIR93_RS23395 () | 37269..37574 | - | 306 | Protein_42 | IS91 family transposase ISSbo1 | Transposase |
| FIR93_RS23400 () | 37600..38339 | + | 740 | Protein_43 | IS3 family transposase IS629 | Transposase |
| FIR93_RS23410 () | 39012..40520 | + | 1509 | WP_001189123.1 | group II intron reverse transcriptase/maturase | - |
| FIR93_RS23415 () | 40610..41083 | + | 474 | Protein_45 | IS3 family transposase IS629 | Transposase |
| FIR93_RS23420 () | 41086..41655 | - | 570 | WP_001336919.1 | Serine protease EspC | VF |
| FIR93_RS23425 () | 41757..42673 | + | 917 | Protein_47 | IS5 family transposase ISKpn26 | Transposase |
| FIR93_RS23430 () | 42691..43004 | - | 314 | Protein_48 | Tn3 family transposase | - |
| FIR93_RS23435 () | 43031..43783 | - | 753 | WP_000734115.1 | alpha/beta hydrolase | - |
| FIR93_RS23440 () | 44025..44897 | + | 873 | WP_000090196.1 | DMT family transporter | - |
| FIR93_RS23445 () | 45028..46251 | + | 1224 | WP_000872613.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| FIR93_RS23450 () | 46437..47210 | - | 774 | WP_032152933.1 | SDR family oxidoreductase | - |
| FIR93_RS23455 () | 47276..47977 | - | 702 | WP_053908471.1 | DsbA family oxidoreductase | - |
| FIR93_RS23460 () | 48043..49149 | - | 1107 | WP_000039982.1 | alkene reductase | - |
| FIR93_RS23465 () | 49363..49692 | + | 330 | WP_002431133.1 | thioredoxin family protein | - |
| FIR93_RS23470 () | 49722..50060 | - | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| FIR93_RS23475 () | 50065..50646 | - | 582 | WP_000210409.1 | HTH-type transcriptional repressor NemR | VF |
| FIR93_RS23480 () | 50788..51345 | - | 558 | WP_000108589.1 | OsmC family protein | - |
| FIR93_RS23485 () | 51530..52009 | - | 480 | Protein_59 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| FIR93_RS23490 () | 52062..52766 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FIR93_RS23495 () | 52832..53119 | + | 288 | Protein_61 | IS1380 family transposase ISEcp1 | Transposase |
| FIR93_RS23500 () | 53375..54250 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| FIR93_RS23505 () | 54297..54629 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| FIR93_RS23510 () | 54643..56886 | + | 2244 | Protein_64 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FIR93_RS23515 () | 56951..57655 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FIR93_RS23520 () | 57709..58149 | - | 441 | Protein_66 | CatB-related O-acetyltransferase | - |
| FIR93_RS23525 () | 58287..59117 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| FIR93_RS23530 () | 59248..59802 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| FIR93_RS23535 () | 59946..60650 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FIR93_RS23540 () | 60716..62230 | + | 1515 | Protein_70 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FIR93_RS23545 () | 62272..62514 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| FIR93_RS23550 () | 62546..63196 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| FIR93_RS23555 () | 63302..64501 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| FIR93_RS23560 () | 64533..65417 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| FIR93_RS23565 () | 65555..65962 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| FIR93_RS23570 () | 65951..66700 | + | 750 | Protein_76 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FIR93_RS23575 () | 66724..67329 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| FIR93_RS23580 () | 67424..70321 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| FIR93_RS23585 () | 70458..70859 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FIR93_RS23590 () | 70792..71049 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FIR93_RS23595 () | 71142..71795 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| FIR93_RS23600 () | 72734..73591 | - | 858 | WP_032152935.1 | incFII family plasmid replication initiator RepA | - |
| FIR93_RS23605 () | 73584..73658 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| FIR93_RS23610 () | 73893..74150 | - | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| FIR93_RS23615 () | 74555..75577 | + | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| FIR93_RS23620 () | 76049..76402 | + | 354 | WP_000005489.1 | hypothetical protein | - |
| FIR93_RS23625 () | 76815..77393 | - | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| FIR93_RS23630 () | 77426..78123 | + | 698 | Protein_88 | IS1 family transposase IS1S | Transposase |
| FIR93_RS23635 () | 78232..78594 | + | 363 | WP_059330006.1 | IS66 family transposase ISEc23 | Transposase |
| FIR93_RS23640 () | 78591..78941 | + | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| FIR93_RS23645 () | 78972..79193 | + | 222 | WP_000080227.1 | hypothetical protein | - |
| FIR93_RS23650 () | 79145..79486 | + | 342 | Protein_92 | transposase | - |
| FIR93_RS23655 () | 79550..80029 | - | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| FIR93_RS23660 () | 80110..81513 | - | 1404 | WP_000514417.1 | YfcC family protein | - |
| FIR93_RS23665 () | 81561..82565 | - | 1005 | WP_000154545.1 | Ornithine carbamoyltransferase | VF |
| FIR93_RS23670 () | 82650..83561 | - | 912 | WP_000440183.1 | carbamate kinase | - |
| FIR93_RS23675 () | 83572..84792 | - | 1221 | WP_000410951.1 | arginine deiminase | - |
| FIR93_RS23680 () | 85685..86167 | + | 483 | Protein_98 | VENN motif pre-toxin domain-containing protein | - |
| FIR93_RS23685 () | 86113..86559 | - | 447 | Protein_99 | incFII family plasmid replication initiator RepA | - |
| FIR93_RS23690 () | 86552..86626 | - | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| FIR93_RS23695 () | 86862..87119 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| FIR93_RS23700 () | 87403..87609 | - | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 87596..87657 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 87596..87657 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 87596..87657 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 87596..87657 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| FIR93_RS23705 () | 87796..87978 | - | 183 | WP_000968309.1 | hypothetical protein | - |
| FIR93_RS23710 () | 88079..88695 | + | 617 | Protein_104 | IS1 family transposase IS1G | Transposase |
| FIR93_RS23715 () | 88733..90304 | - | 1572 | WP_023149734.1 | IS66 family transposase ISCro1 | Transposase |
| FIR93_RS23720 () | 90324..90671 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| FIR93_RS23725 () | 90671..91348 | - | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| FIR93_RS24385 () | 91403..91492 | + | 90 | Protein_108 | IS1 family transposase | - |
| FIR93_RS23735 () | 91793..92005 | - | 213 | WP_005012601.1 | hypothetical protein | - |
| FIR93_RS23740 () | 92139..92699 | - | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| FIR93_RS23745 () | 92754..92900 | - | 147 | Protein_111 | hypothetical protein | - |
| FIR93_RS23750 () | 92893..93096 | - | 204 | Protein_112 | antirestriction protein | - |
| FIR93_RS23760 () | 93633..94403 | - | 771 | WP_001006251.1 | hypothetical protein | - |
| FIR93_RS23765 () | 94448..94882 | - | 435 | WP_001546462.1 | DUF1380 family protein | - |
| FIR93_RS23770 () | 94896..95117 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| FIR93_RS23775 () | 95118..95801 | - | 684 | WP_032181561.1 | DNA methylase | - |
| FIR93_RS23780 () | 95878..96182 | - | 305 | Protein_117 | hypothetical protein | - |
| FIR93_RS23785 () | 96186..97088 | - | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| FIR93_RS23790 () | 97826..98797 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FIR93_RS23795 () | 98797..99963 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| FIR93_RS23800 () | 100551..101306 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| FIR93_RS23805 () | 102028..102834 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| FIR93_RS23810 () | 102835..103140 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| FIR93_RS23815 () | 103142..103360 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| FIR93_RS23820 () | 103920..104150 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| FIR93_RS23825 () | 104147..104563 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FIR93_RS23830 () | 104638..106203 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| FIR93_RS23835 () | 106188..107210 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| FIR93_RS23840 () | 107464..108150 | - | 687 | Protein_129 | IS1 family transposase IS1S | Transposase |
| FIR93_RS23845 () | 108676..110877 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| FIR93_RS23850 () | 110959..112236 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| FIR93_RS23855 () | 112233..113975 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| FIR93_RS23860 () | 113975..114922 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| FIR93_RS23865 () | 114923..116647 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| FIR93_RS23870 () | 116783..117976 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| FIR93_RS23875 () | 118356..118736 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| FIR93_RS23880 () | 119077..119490 | - | 414 | Protein_137 | phosphopyruvate hydratase | - |
| FIR93_RS23885 () | 119488..119745 | + | 258 | Protein_138 | Tn3 family transposase | - |
| FIR93_RS23890 () | 119979..120836 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| FIR93_RS23895 () | 120833..121690 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| FIR93_RS23900 () | 121687..122514 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| FIR93_RS23905 () | 122514..123428 | - | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| FIR93_RS23910 () | 123784..124481 | + | 698 | Protein_143 | IS1 family transposase IS1G | Transposase |
| FIR93_RS23915 () | 124661..125174 | - | 514 | Protein_144 | DUF4113 domain-containing protein | - |
| FIR93_RS24390 () | 125235..125339 | - | 105 | Protein_145 | AAA family ATPase | - |
| FIR93_RS23920 () | 125341..125664 | - | 324 | Protein_146 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|