MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 132733 bp
Accession: NZ_CP040742 Location: 1..132733 Organism: Enterococcus faecium strain VRE1 Replicon: plasmid pVRE1-VanA
Accession: NZ_CP040742 Location: 1..132733 Organism: Enterococcus faecium strain VRE1 Replicon: plasmid pVRE1-VanA
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGY81_RS16220 () | 987..1160 | - | 174 | WP_002320797.1 | hypothetical protein | - |
| FGY81_RS15150 () | 1163..1561 | - | 399 | WP_002320796.1 | hypothetical protein | - |
| FGY81_RS15155 () | 1777..2832 | + | 1056 | WP_002320795.1 | ParM/StbA family protein | - |
| FGY81_RS15160 () | 2852..3205 | + | 354 | WP_002320794.1 | hypothetical protein | - |
| FGY81_RS15165 () | 3387..3683 | - | 297 | WP_002320793.1 | hypothetical protein | - |
| FGY81_RS15170 () | 3687..4505 | - | 819 | WP_002320792.1 | AAA family ATPase | - |
| FGY81_RS15180 () | 4731..4952 | + | 222 | WP_002320791.1 | DUF1778 domain-containing protein | - |
| FGY81_RS15185 () | 4954..5220 | + | 267 | WP_002320790.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FGY81_RS15190 () | 5204..5878 | + | 675 | WP_002320789.1 | hypothetical protein | - |
| FGY81_RS15200 () | 6321..6605 | + | 285 | WP_002320788.1 | hypothetical protein | - |
| FGY81_RS15205 () | 6612..6857 | + | 246 | WP_002320787.1 | hypothetical protein | - |
| FGY81_RS15210 () | 6879..7133 | + | 255 | WP_002320786.1 | hypothetical protein | - |
| FGY81_RS15215 () | 7215..7400 | + | 186 | WP_002320785.1 | type II toxin-antitoxin system HicA family toxin | - |
| FGY81_RS15220 () | 7467..7862 | + | 396 | WP_002320784.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| FGY81_RS15225 () | 7852..8229 | + | 378 | WP_002320783.1 | hypothetical protein | - |
| FGY81_RS15230 () | 8251..8625 | + | 375 | WP_010733718.1 | hypothetical protein | - |
| FGY81_RS15235 () | 8931..9329 | - | 399 | WP_002320781.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| FGY81_RS15240 () | 9508..10656 | - | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FGY81_RS15245 () | 10673..11077 | - | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FGY81_RS15250 () | 11628..12431 | + | 804 | WP_002320777.1 | replication initiation protein | - |
| FGY81_RS15255 () | 13015..13470 | + | 456 | WP_002320776.1 | hypothetical protein | - |
| FGY81_RS15260 () | 13589..14647 | + | 1059 | WP_002321771.1 | hypothetical protein | - |
| FGY81_RS15265 () | 14689..16638 | + | 1950 | WP_002320773.1 | ATP-dependent Clp protease ATP-binding subunit | - |
| FGY81_RS15270 () | 16641..20282 | + | 3642 | WP_002320772.1 | hypothetical protein | - |
| FGY81_RS15275 () | 20681..21019 | + | 339 | WP_002320771.1 | hypothetical protein | - |
| FGY81_RS15280 () | 21129..21371 | + | 243 | WP_002320770.1 | hypothetical protein | - |
| FGY81_RS15285 () | 21371..23533 | + | 2163 | WP_002320769.1 | hypothetical protein | - |
| FGY81_RS15290 () | 23545..23778 | + | 234 | WP_002320768.1 | LPXTG cell wall anchor domain-containing protein | - |
| FGY81_RS15295 () | 23768..24634 | + | 867 | WP_002320767.1 | hypothetical protein | - |
| FGY81_RS15300 () | 24649..26619 | + | 1971 | WP_002320766.1 | hypothetical protein | - |
| FGY81_RS15305 () | 26785..27012 | + | 228 | WP_002320765.1 | hypothetical protein | - |
| FGY81_RS15310 () | 27009..27503 | + | 495 | WP_002320764.1 | hypothetical protein | - |
| FGY81_RS15315 () | 27677..28012 | + | 336 | WP_002320763.1 | hypothetical protein | - |
| FGY81_RS15320 () | 28188..29360 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| FGY81_RS15325 () | 29630..31213 | - | 1584 | WP_002360084.1 | hypothetical protein | - |
| FGY81_RS15330 () | 31335..31919 | + | 585 | WP_002321028.1 | hypothetical protein | - |
| FGY81_RS15335 () | 31930..32175 | + | 246 | WP_002321027.1 | hypothetical protein | - |
| FGY81_RS15340 () | 32181..32903 | + | 723 | WP_010733700.1 | hypothetical protein | - |
| FGY81_RS15345 () | 33034..33777 | + | 744 | WP_002321025.1 | hypothetical protein | - |
| FGY81_RS15350 () | 33783..34148 | + | 366 | WP_002321024.1 | hypothetical protein | - |
| FGY81_RS15355 () | 34164..34694 | + | 531 | WP_002321023.1 | hypothetical protein | - |
| FGY81_RS15360 () | 34823..35083 | + | 261 | WP_002321022.1 | hypothetical protein | - |
| FGY81_RS15365 () | 35320..37560 | + | 2241 | WP_138821078.1 | hypothetical protein | - |
| FGY81_RS15370 () | 37698..38495 | + | 798 | WP_002350503.1 | hypothetical protein | - |
| FGY81_RS15375 () | 38535..38717 | + | 183 | WP_002350502.1 | hypothetical protein | - |
| FGY81_RS15380 () | 38761..39048 | + | 288 | WP_002321018.1 | hypothetical protein | - |
| FGY81_RS15385 () | 39085..39372 | + | 288 | WP_002321017.1 | hypothetical protein | - |
| FGY81_RS15390 () | 39463..39702 | + | 240 | WP_002350501.1 | hypothetical protein | - |
| FGY81_RS15395 () | 39830..40159 | + | 330 | WP_002350500.1 | hypothetical protein | - |
| FGY81_RS15400 () | 40212..40514 | + | 303 | Protein_49 | hypothetical protein | - |
| FGY81_RS15405 () | 40569..41249 | - | 681 | WP_013646119.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15410 () | 41324..41446 | + | 123 | Protein_51 | transposase | - |
| FGY81_RS15415 () | 41463..42611 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FGY81_RS15420 () | 42768..43247 | - | 480 | WP_016922278.1 | hypothetical protein | - |
| FGY81_RS15425 () | 43367..44704 | + | 1338 | WP_002350497.1 | CHAP domain-containing protein | - |
| FGY81_RS15430 () | 44727..45254 | + | 528 | WP_002350496.1 | hypothetical protein | - |
| FGY81_RS15435 () | 45241..45804 | + | 564 | WP_016922277.1 | hypothetical protein | - |
| FGY81_RS15440 () | 46227..46964 | + | 738 | WP_010782614.1 | hypothetical protein | - |
| FGY81_RS15445 () | 46981..47397 | - | 417 | WP_002350493.1 | hypothetical protein | - |
| FGY81_RS15450 () | 47789..49036 | + | 1248 | WP_002350491.1 | C39 family peptidase | - |
| FGY81_RS15455 () | 49306..51696 | + | 2391 | WP_016922338.1 | Cys-Gln thioester bond-forming surface protein | - |
| FGY81_RS15460 () | 51745..53580 | + | 1836 | WP_002350584.1 | isopeptide-forming domain-containing fimbrial protein | - |
| FGY81_RS15465 () | 53649..54512 | + | 864 | WP_002350583.1 | hypothetical protein | VF |
| FGY81_RS15470 () | 54502..55611 | + | 1110 | WP_002350582.1 | hypothetical protein | VF |
| FGY81_RS15475 () | 55950..56750 | + | 801 | WP_010730977.1 | hypothetical protein | - |
| FGY81_RS15480 () | 56838..57644 | + | 807 | WP_002320858.1 | hypothetical protein | - |
| FGY81_RS15485 () | 57876..58745 | + | 870 | WP_010729859.1 | hypothetical protein | VF |
| FGY81_RS15490 () | 58765..59112 | + | 348 | WP_002320856.1 | hypothetical protein | - |
| FGY81_RS15495 () | 59125..60387 | + | 1263 | WP_002320855.1 | hypothetical protein | - |
| FGY81_RS15500 () | 60467..61843 | + | 1377 | WP_002320854.1 | DNA translocase SftA | VF |
| FGY81_RS15505 () | 61840..62469 | + | 630 | WP_002320853.1 | hypothetical protein | - |
| FGY81_RS15510 () | 62488..62967 | + | 480 | WP_002350578.1 | hypothetical protein | - |
| FGY81_RS15515 () | 63469..63522 | + | 54 | Protein_72 | hypothetical protein | - |
| FGY81_RS15520 () | 63526..64125 | + | 600 | WP_016922336.1 | rhomboid family intramembrane serine protease | - |
| FGY81_RS15525 () | 64141..64617 | + | 477 | WP_002350576.1 | hypothetical protein | - |
| FGY81_RS15530 () | 64634..65536 | + | 903 | WP_016922335.1 | hypothetical protein | - |
| FGY81_RS15535 () | 65609..65803 | + | 195 | WP_138821081.1 | hypothetical protein | - |
| FGY81_RS15540 () | 65982..66386 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FGY81_RS15545 () | 66403..67551 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FGY81_RS15550 () | 67799..68227 | + | 429 | WP_042957131.1 | hypothetical protein | - |
| FGY81_RS15555 () | 68462..69049 | + | 588 | WP_002350572.1 | hypothetical protein | - |
| FGY81_RS15560 () | 69049..69948 | + | 900 | WP_002350571.1 | RusA family crossover junction endodeoxyribonuclease | - |
| FGY81_RS15565 () | 69948..70862 | + | 915 | WP_016922248.1 | hypothetical protein | - |
| FGY81_RS15570 () | 70914..71129 | + | 216 | WP_016922247.1 | hypothetical protein | - |
| FGY81_RS15575 () | 71319..71573 | + | 255 | WP_002350568.1 | hypothetical protein | - |
| FGY81_RS15580 () | 71752..72801 | + | 1050 | WP_002350567.1 | C39 family peptidase | - |
| FGY81_RS15585 () | 72978..73208 | + | 231 | WP_002320840.1 | hypothetical protein | - |
| FGY81_RS15590 () | 73211..73468 | + | 258 | WP_002350566.1 | hypothetical protein | - |
| FGY81_RS15595 () | 73685..74560 | + | 876 | WP_010730973.1 | hypothetical protein | - |
| FGY81_RS15600 () | 74570..75364 | + | 795 | WP_010730972.1 | hypothetical protein | - |
| FGY81_RS15605 () | 75393..76511 | + | 1119 | WP_010730971.1 | hypothetical protein | - |
| FGY81_RS15610 () | 76544..76864 | + | 321 | WP_002321530.1 | hypothetical protein | - |
| FGY81_RS15615 () | 77119..77808 | + | 690 | WP_002347494.1 | hypothetical protein | - |
| FGY81_RS15620 () | 77809..78012 | + | 204 | WP_002350561.1 | hypothetical protein | - |
| FGY81_RS15625 () | 78032..78667 | + | 636 | Protein_94 | hypothetical protein | - |
| FGY81_RS15630 () | 78742..79422 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15635 () | 79820..79915 | + | 96 | WP_106913803.1 | type I toxin-antitoxin system Fst family toxin | - |
| FGY81_RS15640 () | 80615..80899 | + | 285 | WP_000353844.1 | hypothetical protein | - |
| FGY81_RS15645 () | 80902..81318 | + | 417 | WP_001232859.1 | hypothetical protein | - |
| FGY81_RS15650 () | 81455..82174 | - | 720 | WP_002311815.1 | replication initiation protein | - |
| FGY81_RS15655 () | 82566..83246 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15660 () | 83301..83444 | - | 144 | Protein_101 | IS256 family transposase IS1542 | Transposase |
| FGY81_RS15670 () | 83596..84291 | + | 696 | WP_001280781.1 | Transcriptional regulatory protein WalR | VF |
| FGY81_RS15675 () | 84269..85423 | + | 1155 | WP_002305818.1 | VanA-type vancomycin resistance histidine kinase VanS | - |
| FGY81_RS15680 () | 85638..86606 | + | 969 | WP_001059542.1 | D-specific alpha-keto acid dehydrogenase | ARG |
| FGY81_RS15685 () | 86599..87630 | + | 1032 | WP_001079845.1 | Vancomycin/teicoplanin A-type resistance protein VanA | ARG |
| FGY81_RS15690 () | 87636..88244 | + | 609 | WP_000402347.1 | D-alanyl-D-alanine dipeptidase | ARG |
| FGY81_RS15695 () | 88420..89100 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15700 () | 89395..90306 | + | 912 | WP_001812592.1 | D-Ala-D-Ala carboxypeptidase VanY-A | - |
| FGY81_RS15705 () | 90459..90944 | + | 486 | WP_000516404.1 | glycopeptide resistance protein VanZ-A | - |
| FGY81_RS15710 () | 91231..91560 | - | 330 | WP_000754864.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| FGY81_RS15715 () | 91865..92194 | + | 330 | WP_000629052.1 | hypothetical protein | - |
| FGY81_RS15720 () | 92184..92471 | + | 288 | WP_000312841.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FGY81_RS15725 () | 92750..93313 | - | 564 | WP_000017403.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| FGY81_RS15730 () | 93506..94078 | - | 573 | WP_002293724.1 | HAD-IIIA family hydrolase | - |
| FGY81_RS15735 () | 94230..94535 | - | 306 | Protein_115 | IS6 family transposase IS1216V | Transposase |
| FGY81_RS15740 () | 94593..95273 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15745 () | 95393..95578 | + | 186 | WP_080441113.1 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase | - |
| FGY81_RS15750 () | 95585..96094 | + | 510 | WP_138821094.1 | hypothetical protein | - |
| FGY81_RS15755 () | 96148..96552 | + | 405 | Protein_119 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15760 () | 96602..97282 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15765 () | 97452..98057 | + | 606 | WP_000599739.1 | cell filamentation protein | - |
| FGY81_RS15770 () | 98073..98645 | + | 573 | WP_002303206.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| FGY81_RS15780 () | 99118..99690 | - | 573 | WP_138821102.1 | IS3 family transposase ISBce13 | Transposase |
| FGY81_RS15790 () | 100994..101248 | - | 255 | WP_002322130.1 | IS3 family transposase ISBce13 | Transposase |
| FGY81_RS15795 () | 101359..101613 | - | 255 | WP_000199136.1 | IS3 family transposase ISBce13 | Transposase |
| FGY81_RS15800 () | 101806..102081 | - | 276 | WP_001196543.1 | hypothetical protein | - |
| FGY81_RS15805 () | 102053..103006 | - | 954 | WP_000429439.1 | ParA family protein | - |
| FGY81_RS15810 () | 103618..105111 | + | 1494 | WP_000947691.1 | primase C-terminal domain-containing protein | - |
| FGY81_RS15815 () | 105246..105542 | + | 297 | WP_138821096.1 | type III secretion system protein PrgN | - |
| FGY81_RS15820 () | 105566..106525 | - | 960 | WP_002287225.1 | IS30 family transposase IS1062 | Transposase |
| FGY81_RS15825 () | 106708..107307 | + | 600 | Protein_132 | hypothetical protein | - |
| FGY81_RS15830 () | 107383..108063 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15835 () | 108339..108644 | + | 306 | WP_099097609.1 | site-specific recombinase | - |
| FGY81_RS15840 () | 108787..109011 | + | 225 | WP_002303393.1 | helix-turn-helix transcriptional regulator | Antitoxin Detail |
| FGY81_RS15845 () | 109026..109895 | + | 870 | WP_002303392.1 | nucleotidyltransferase domain-containing protein | Toxin Detail |
| FGY81_RS15850 () | 109876..110610 | + | 735 | WP_000662263.1 | class I SAM-dependent methyltransferase | - |
| FGY81_RS15855 () | 110643..111551 | + | 909 | WP_001255866.1 | Aminoglycoside 6-adenylyltransferase | ARG |
| FGY81_RS15860 () | 111548..111796 | + | 249 | WP_002347175.1 | hypothetical protein | - |
| FGY81_RS15865 () | 111799..112707 | - | 909 | WP_002324522.1 | IS982 family transposase ISEfm1 | Transposase |
| FGY81_RS15870 () | 112808..114103 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| FGY81_RS15875 () | 114348..114599 | + | 252 | Protein_142 | GNAT family N-acetyltransferase | - |
| FGY81_RS15880 () | 114692..115486 | + | 795 | WP_001096887.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| FGY81_RS15890 () | 115762..116304 | + | 543 | WP_002321977.1 | HTH domain-containing protein | - |
| FGY81_RS15895 () | 116334..117014 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15900 () | 117068..118042 | - | 975 | WP_138821098.1 | replication initiation protein | - |
| FGY81_RS15910 () | 119232..119435 | - | 204 | WP_002321382.1 | hypothetical protein | - |
| FGY81_RS15915 () | 119447..119980 | - | 534 | WP_002334266.1 | hypothetical protein | - |
| FGY81_RS15920 () | 120637..121785 | - | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FGY81_RS15925 () | 121802..122206 | - | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| FGY81_RS15930 () | 122539..122955 | - | 417 | WP_002305824.1 | hypothetical protein | - |
| FGY81_RS15935 () | 122957..123238 | - | 282 | WP_002347613.1 | hypothetical protein | - |
| FGY81_RS15940 () | 123614..124138 | - | 525 | WP_044383356.1 | DUF536 domain-containing protein | - |
| FGY81_RS15945 () | 124232..124912 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15950 () | 124974..125492 | + | 519 | WP_175415673.1 | hypothetical protein | - |
| FGY81_RS15960 () | 125873..126052 | + | 180 | WP_001120991.1 | hypothetical protein | - |
| FGY81_RS15965 () | 126183..126452 | + | 270 | WP_000388479.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| FGY81_RS15970 () | 126445..126702 | + | 258 | WP_000588503.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| FGY81_RS15975 () | 127161..128165 | + | 1005 | WP_000455809.1 | hypothetical protein | - |
| FGY81_RS15980 () | 128446..129126 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| FGY81_RS15985 () | 129181..129615 | + | 435 | Protein_161 | JAB domain-containing protein | - |
| FGY81_RS15990 () | 129641..130186 | + | 546 | WP_002320753.1 | hypothetical protein | - |
| FGY81_RS15995 () | 130187..130753 | + | 567 | WP_002320752.1 | hypothetical protein | - |
| FGY81_RS16000 () | 130768..131016 | + | 249 | WP_002350598.1 | hypothetical protein | - |
| FGY81_RS16005 () | 131036..131275 | + | 240 | WP_002320750.1 | hypothetical protein | - |
| FGY81_RS16015 () | 131646..131927 | + | 282 | WP_010733706.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| FGY81_RS16020 () | 131917..132258 | + | 342 | WP_002320747.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|