MGE detailed information
MGE type: Conjugative plasmid MGE length: 117599 bp
Accession: NZ_CP038455 Location: 1..117599 Organism: Escherichia coli strain EC-129 Replicon: plasmid pEC129_2
Accession: NZ_CP038455 Location: 1..117599 Organism: Escherichia coli strain EC-129 Replicon: plasmid pEC129_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4Z89_RS24575 () | 1..978 | + | 978 | WP_072652232.1 | RepB family plasmid replication initiator protein | - |
| E4Z89_RS24580 () | 1263..1994 | - | 732 | WP_072652233.1 | tyrosine-type recombinase/integrase | - |
| E4Z89_RS24585 () | 2224..2928 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E4Z89_RS24595 () | 3403..4416 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| E4Z89_RS24600 () | 4708..5262 | + | 555 | WP_063840321.1 | hypothetical protein | ARG |
| E4Z89_RS24605 () | 5341..5814 | + | 474 | WP_001749985.1 | Dihydrofolate reductase type 1 | ARG |
| E4Z89_RS24610 () | 5995..6840 | + | 846 | WP_001749984.1 | Streptomycin 3''-adenylyltransferase | ARG |
| E4Z89_RS24615 () | 6957..7304 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| E4Z89_RS24620 () | 7298..8137 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| E4Z89_RS24625 () | 8542..10083 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| E4Z89_RS24630 () | 10410..10595 | + | 186 | WP_046788536.1 | hypothetical protein | - |
| E4Z89_RS24635 () | 10676..11431 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| E4Z89_RS24640 () | 11601..12461 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| E4Z89_RS24645 () | 12644..13003 | - | 360 | Protein_13 | Tn3 family transposase TnpR_Tn3 | Transposase |
| E4Z89_RS24650 () | 13057..13761 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E4Z89_RS24655 () | 13994..14854 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| E4Z89_RS24660 () | 14867..15409 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| E4Z89_RS24665 () | 15891..16082 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| E4Z89_RS24670 () | 16106..16333 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| E4Z89_RS24675 () | 16384..17520 | + | 1137 | WP_000080861.1 | DUF3883 domain-containing protein | - |
| E4Z89_RS24680 () | 17635..19005 | + | 1371 | WP_000971921.1 | IS1182 family transposase ISCfr1 | Transposase |
| E4Z89_RS24685 () | 19826..20686 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| E4Z89_RS24695 () | 20917..21753 | - | 837 | WP_001495812.1 | hypothetical protein | ARG |
| E4Z89_RS24700 () | 21753..22556 | - | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| E4Z89_RS24705 () | 22617..23432 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| E4Z89_RS24715 () | 23762..23938 | + | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| E4Z89_RS24720 () | 24120..25124 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| E4Z89_RS24725 () | 25203..28169 | - | 2967 | WP_072652147.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| E4Z89_RS24730 () | 28172..28486 | - | 315 | Protein_28 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| E4Z89_RS24740 () | 28540..29244 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E4Z89_RS24745 () | 29314..29787 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| E4Z89_RS24750 () | 29943..30956 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| E4Z89_RS24760 () | 31159..31509 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| E4Z89_RS24765 () | 31685..32245 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| E4Z89_RS26630 () | 32249..32620 | + | 372 | Protein_34 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| E4Z89_RS26635 () | 32600..32845 | + | 246 | WP_041937891.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| E4Z89_RS24775 () | 32877..33527 | - | 651 | WP_038989485.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| E4Z89_RS24780 () | 33633..34832 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| E4Z89_RS24785 () | 34864..35748 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| E4Z89_RS24790 () | 35886..36293 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| E4Z89_RS24795 () | 36282..38033 | + | 1752 | Protein_40 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| E4Z89_RS24800 () | 38248..40020 | - | 1773 | WP_001262767.1 | DUF262 domain-containing protein | - |
| E4Z89_RS24805 () | 40305..40706 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| E4Z89_RS24810 () | 40639..40896 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| E4Z89_RS24815 () | 40989..41642 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| E4Z89_RS24825 () | 42581..43438 | - | 858 | WP_072652179.1 | incFII family plasmid replication initiator RepA | - |
| E4Z89_RS24830 () | 43431..43505 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| E4Z89_RS24840 () | 43742..43996 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| E4Z89_RS24845 () | 44236..44826 | - | 591 | WP_063101963.1 | DUF2726 domain-containing protein | - |
| E4Z89_RS24850 () | 44865..45073 | - | 209 | Protein_49 | hemolysin expression modulator Hha | - |
| E4Z89_RS24855 () | 45119..45580 | - | 462 | WP_072652178.1 | thermonuclease family protein | - |
| E4Z89_RS26640 () | 45542..45643 | - | 102 | Protein_51 | nuclease | - |
| E4Z89_RS24860 () | 45822..46034 | - | 213 | WP_072652177.1 | hypothetical protein | - |
| E4Z89_RS24865 () | 46165..46725 | - | 561 | WP_000139345.1 | fertility inhibition protein FinO | - |
| E4Z89_RS24870 () | 46780..47526 | - | 747 | WP_001825166.1 | conjugal transfer pilus acetylase TraX | - |
| E4Z89_RS24875 () | 47546..52816 | - | 5271 | WP_072652176.1 | Multifunctional conjugation protein TraI | Relaxase |
| E4Z89_RS24880 () | 52816..54987 | - | 2172 | WP_072652175.1 | type IV conjugative transfer system coupling protein TraD | - |
| E4Z89_RS24885 () | 55038..55778 | - | 741 | WP_021514832.1 | hypothetical protein | - |
| E4Z89_RS24890 () | 55981..56712 | - | 732 | WP_000782451.1 | complement resistance protein TraT | - |
| E4Z89_RS24895 () | 56761..57246 | - | 486 | WP_000605868.1 | hypothetical protein | - |
| E4Z89_RS24900 () | 57262..60084 | - | 2823 | WP_072859393.1 | conjugal transfer mating pair stabilization protein TraG | - |
| E4Z89_RS24905 () | 60081..61454 | - | 1374 | WP_021532658.1 | conjugal transfer protein TraH | - |
| E4Z89_RS24910 () | 61454..61816 | - | 363 | WP_071587080.1 | P-type conjugative transfer protein TrbJ | - |
| E4Z89_RS24915 () | 61746..62291 | - | 546 | WP_044804936.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| E4Z89_RS24920 () | 62278..62559 | - | 282 | WP_000549795.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| E4Z89_RS24925 () | 62675..63418 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| E4Z89_RS24930 () | 63411..63668 | - | 258 | WP_000864341.1 | conjugal transfer protein TrbE | - |
| E4Z89_RS24935 () | 63695..65545 | - | 1851 | WP_072652173.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| E4Z89_RS24940 () | 65542..66180 | - | 639 | WP_000777692.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| E4Z89_RS24945 () | 66189..67181 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| E4Z89_RS24950 () | 67178..67810 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| E4Z89_RS24955 () | 67807..68193 | - | 387 | WP_000214096.1 | type-F conjugative transfer system protein TrbI | - |
| E4Z89_RS24960 () | 68190..70820 | - | 2631 | WP_000069764.1 | type IV secretion system protein TraC | - |
| E4Z89_RS26645 () | 70946..71122 | - | 177 | WP_159048805.1 | hypothetical protein | - |
| E4Z89_RS24965 () | 71179..72201 | + | 1023 | WP_001349747.1 | IS21 family transposase IS100kyp | Transposase |
| E4Z89_RS24970 () | 72201..72980 | + | 780 | WP_001323403.1 | IS21 family transposase IS100kyp | Transposase |
| E4Z89_RS24975 () | 73046..73267 | - | 222 | Protein_76 | hypothetical protein | - |
| E4Z89_RS24980 () | 73349..74317 | - | 969 | WP_013087110.1 | IS5 family transposase IS903B | Transposase |
| E4Z89_RS24990 () | 74656..75129 | - | 474 | WP_053895102.1 | hypothetical protein | - |
| E4Z89_RS24995 () | 75122..75535 | - | 414 | WP_000549581.1 | hypothetical protein | - |
| E4Z89_RS25000 () | 75528..75749 | - | 222 | WP_072652238.1 | conjugal transfer protein TraR | - |
| E4Z89_RS25005 () | 75884..76399 | - | 516 | WP_000809874.1 | type IV conjugative transfer system lipoprotein TraV | - |
| E4Z89_RS25010 () | 76396..76764 | - | 369 | WP_001315561.1 | conjugal transfer protein TrbD | - |
| E4Z89_RS25015 () | 76703..77293 | - | 591 | WP_000002784.1 | conjugal transfer protein TraP | - |
| E4Z89_RS25020 () | 77283..78710 | - | 1428 | WP_000146657.1 | conjugal transfer protein TraB | - |
| E4Z89_RS25025 () | 78710..79414 | - | 705 | WP_148724787.1 | type-F conjugative transfer system secretin TraK | - |
| E4Z89_RS25030 () | 79425..79991 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| E4Z89_RS25035 () | 80013..80324 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| E4Z89_RS25040 () | 80339..80698 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| E4Z89_RS25045 () | 80732..80959 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| E4Z89_RS25050 () | 81053..81739 | - | 687 | WP_001825184.1 | PAS domain-containing protein | - |
| E4Z89_RS25055 () | 81930..82313 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| E4Z89_RS25060 () | 82590..83237 | + | 648 | WP_000614935.1 | hypothetical protein | VF |
| E4Z89_RS25065 () | 83534..84355 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| E4Z89_RS25070 () | 84473..84760 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| E4Z89_RS25075 () | 84785..84991 | - | 207 | WP_000547971.1 | hypothetical protein | - |
| E4Z89_RS25090 () | 85682..85840 | - | 159 | WP_034169443.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 85884..86108 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 85884..86108 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 85884..86108 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 85884..86108 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| E4Z89_RS26650 () | 85920..86108 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| E4Z89_RS25095 () | 86120..86839 | - | 720 | WP_050858785.1 | plasmid SOS inhibition protein A | - |
| E4Z89_RS25100 () | 86836..87270 | - | 435 | WP_032217500.1 | conjugation system SOS inhibitor PsiB | - |
| E4Z89_RS25105 () | 87325..89283 | - | 1959 | WP_072652246.1 | ParB/RepB/Spo0J family partition protein | - |
| E4Z89_RS25110 () | 89348..89581 | - | 234 | WP_000006030.1 | DUF905 family protein | - |
| E4Z89_RS25115 () | 89643..90182 | - | 540 | WP_009426937.1 | single-stranded DNA-binding protein | - |
| E4Z89_RS25120 () | 90208..90414 | - | 207 | WP_000547971.1 | hypothetical protein | - |
| E4Z89_RS25140 () | 91094..91657 | - | 564 | WP_001470147.1 | class I SAM-dependent methyltransferase | - |
| E4Z89_RS25145 () | 91705..93066 | - | 1362 | WP_050858699.1 | DUF3560 domain-containing protein | - |
| E4Z89_RS25150 () | 93118..93348 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| E4Z89_RS25160 () | 93864..94112 | + | 249 | WP_072048988.1 | hypothetical protein | - |
| E4Z89_RS25170 () | 94384..94575 | - | 192 | WP_045177269.1 | hypothetical protein | - |
| E4Z89_RS25175 () | 94572..94994 | - | 423 | WP_050858697.1 | DUF1380 family protein | - |
| E4Z89_RS25180 () | 95041..95343 | - | 303 | WP_077793411.1 | antirestriction protein | - |
| E4Z89_RS26655 () | 95879..96649 | - | 771 | WP_175393454.1 | hypothetical protein | - |
| E4Z89_RS25195 () | 96694..97128 | - | 435 | WP_000274456.1 | DUF1380 family protein | - |
| E4Z89_RS25200 () | 97142..97363 | - | 222 | WP_001104885.1 | hypothetical protein | - |
| E4Z89_RS25205 () | 97364..98047 | - | 684 | WP_000086160.1 | DNA methylase | - |
| E4Z89_RS25210 () | 98123..98428 | - | 306 | WP_032155763.1 | hypothetical protein | - |
| E4Z89_RS25215 () | 98432..99334 | - | 903 | WP_077872020.1 | DUF1281 domain-containing protein | - |
| E4Z89_RS25225 () | 99752..100000 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| E4Z89_RS25230 () | 99997..100434 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| E4Z89_RS25235 () | 100434..101705 | + | 1272 | WP_064198699.1 | Y-family DNA polymerase | - |
| E4Z89_RS25240 () | 101710..102102 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| E4Z89_RS25245 () | 102107..103078 | - | 972 | WP_001103697.1 | hypothetical protein | - |
| E4Z89_RS25250 () | 103307..103951 | + | 645 | WP_000633913.1 | AAA family ATPase | - |
| E4Z89_RS25255 () | 103945..104220 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| E4Z89_RS25260 () | 104412..104838 | - | 427 | Protein_124 | tyrosine-type recombinase/integrase | - |
| E4Z89_RS25265 () | 105018..105248 | + | 231 | Protein_125 | colicin-B | - |
| E4Z89_RS25270 () | 105365..105553 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| E4Z89_RS25275 () | 105563..106762 | + | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| E4Z89_RS25280 () | 106933..107931 | + | 999 | Protein_128 | MFS transporter | - |
| E4Z89_RS25285 () | 107903..108928 | + | 1026 | WP_000864945.1 | zinc-binding alcohol dehydrogenase family protein | - |
| E4Z89_RS25290 () | 108987..109658 | - | 672 | WP_046788564.1 | FadR family transcriptional regulator | - |
| E4Z89_RS25295 () | 109753..110295 | - | 543 | Protein_131 | GGDEF domain-containing protein | - |
| E4Z89_RS25300 () | 110312..111009 | - | 698 | Protein_132 | IS1 family transposase IS1R | Transposase |
| E4Z89_RS25305 () | 111061..111189 | - | 129 | Protein_133 | colicin M immunity protein | - |
| E4Z89_RS25310 () | 111361..112170 | - | 810 | WP_000016963.1 | site-specific integrase | - |
| E4Z89_RS25315 () | 112171..112476 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| E4Z89_RS25320 () | 112478..112696 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| E4Z89_RS25335 () | 113164..113859 | + | 696 | WP_072652234.1 | DNA-binding protein | - |
| E4Z89_RS25340 () | 113856..114476 | + | 621 | WP_072652229.1 | hypothetical protein | - |
| E4Z89_RS25345 () | 114473..115261 | + | 789 | WP_072652230.1 | DUF2971 domain-containing protein | - |
| E4Z89_RS25350 () | 115297..116037 | + | 741 | WP_072652231.1 | abortive infection family protein | - |
| E4Z89_RS25355 () | 116196..116825 | - | 630 | Protein_141 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|