MGE detailed information

MGE type: Conjugative plasmid        MGE length: 141411 bp
Accession: NZ_CP035847        Location: 1..141411         Organism: Escherichia coli strain TW10598       Replicon: plasmid pTW10598_141


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXA01_RS23755 (740) 740..961 + 222 WP_000872636.1 hypothetical protein -
EXA01_RS25655 (1292) 1292..1446 - 155 Protein_2 hypothetical protein -
EXA01_RS23765 (1961) 1961..2191 + 231 WP_000218642.1 hypothetical protein -
EXA01_RS23770 (2243) 2243..3604 + 1362 WP_000170687.1 DUF3560 domain-containing protein -
EXA01_RS23775 (3650) 3650..4213 + 564 WP_001297832.1 class I SAM-dependent methyltransferase -
EXA01_RS25660 (4299) 4299..4406 - 108 Protein_6 hypothetical protein -
EXA01_RS23780 (4407) 4407..4556 + 150 Protein_7 single-stranded DNA-binding domain protein -
EXA01_RS23785 (4613) 4613..4846 + 234 WP_000005971.1 DUF905 domain-containing protein -
EXA01_RS23790 (4910) 4910..6877 + 1968 WP_216311695.1 ParB/RepB/Spo0J family partition protein -
EXA01_RS23795 (6932) 6932..7366 + 435 WP_000845967.1 conjugation system SOS inhibitor PsiB -
EXA01_RS23800 (7363) 7363..8082 + 720 WP_000127019.1 plasmid SOS inhibition protein A -
EXA01_RS23805 (8079) 8079..8393 + 315 WP_000872087.1 hypothetical protein -
- (8342) 8342..8535 + 194 NuclAT_0 - -
- (8342) 8342..8535 + 194 NuclAT_0 - -
- (8342) 8342..8535 + 194 NuclAT_0 - -
- (8342) 8342..8535 + 194 NuclAT_0 - -
EXA01_RS25665 (8543) 8543..8695 + 153 Protein_13 FlmC family protein -
EXA01_RS23810 (8643) 8643..8762 + 120 WP_228769536.1 Hok/Gef family protein -
EXA01_RS23815 (9056) 9056..10627 - 1572 WP_000381401.1 IS66 family transposase ISCro1 Transposase
EXA01_RS23820 (10647) 10647..10994 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
EXA01_RS23825 (10994) 10994..11671 - 678 WP_001704819.1 IS66 family transposase ISCro1 Transposase
EXA01_RS23830 (11712) 11712..11939 + 228 WP_140159966.1 hypothetical protein -
EXA01_RS23845 (14308) 14308..14499 + 192 WP_122994480.1 ANR family transcriptional regulator -
EXA01_RS25670 (14655) 14655..14723 + 69 Protein_22 hypothetical protein -
EXA01_RS23855 (15976) 15976..16107 + 132 Protein_24 hypothetical protein -
EXA01_RS23860 (16207) 16207..16401 + 195 WP_047647374.1 transposase -
EXA01_RS23865 (16468) 16468..17490 + 1023 WP_001295213.1 IS21 family transposase IS100kyp Transposase
EXA01_RS23870 (17487) 17487..18269 + 783 WP_001317493.1 IS21 family transposase IS100kyp Transposase
EXA01_RS23875 (18543) 18543..18890 + 348 WP_000612591.1 IS66 family transposase ISEc8 Transposase
EXA01_RS23880 (18940) 18940..20478 + 1539 WP_000998103.1 IS66 family transposase ISEc8 Transposase
EXA01_RS23885 (20526) 20526..20693 + 168 Protein_30 IS91 family transposase ISSbo1 Transposase
EXA01_RS23890 (20755) 20755..21938 - 1184 Protein_31 IS3 family transposase ISKpn38 Transposase
EXA01_RS23895 (22023) 22023..22268 + 246 Protein_32 transposase -
EXA01_RS23900 (22330) 22330..23273 - 944 Protein_33 Lipid A biosynthesis myristoyltransferase 2 VF
EXA01_RS23905 (23338) 23338..24288 - 951 WP_086405437.1 virulence factor VirK -
EXA01_RS23910 (24293) 24293..25381 - 1089 WP_001528375.1 putative hexosyltransferase CapU -
EXA01_RS23915 (25384) 25384..26226 - 843 WP_162749921.1 polysaccharide deacetylase family protein -
EXA01_RS23920 (26470) 26470..27012 - 543 WP_000194544.1 hypothetical protein -
EXA01_RS23925 (27012) 27012..27269 - 258 WP_000343095.1 hypothetical protein -
EXA01_RS23930 (27791) 27791..28009 + 219 WP_000829078.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
EXA01_RS23935 (28011) 28011..28316 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
EXA01_RS23940 (28317) 28317..29123 + 807 WP_000016960.1 site-specific integrase -
EXA01_RS23945 (29301) 29301..29945 + 645 WP_001144037.1 ParA family protein -
EXA01_RS23950 (30032) 30032..30340 + 309 WP_000030204.1 molecular chaperone GroEL -
EXA01_RS25675 (30562) 30562..30939 + 378 WP_000897156.1 IS66 family transposase IS682 Transposase
EXA01_RS23955 (30975) 30975..31855 + 881 Protein_45 IS66 family transposase -
EXA01_RS23960 (32033) 32033..33162 - 1130 Protein_46 IS110 family transposase ISEc45 Transposase
EXA01_RS23965 (33223) 33223..33399 + 177 Protein_47 transposase domain-containing protein -
EXA01_RS23970 (33481) 33481..34646 + 1166 Protein_48 IS21 family transposase IS21 Transposase
EXA01_RS23975 (34646) 34646..35443 + 798 WP_000544814.1 IS21 family transposase IS21 Transposase
EXA01_RS23980 (35570) 35570..35822 + 253 Protein_50 IS3 family transposase -
EXA01_RS23985 (36301) 36301..37026 + 726 WP_001391304.1 Chaperone protein caf1M VF
EXA01_RS23990 (37001) 37001..39445 + 2445 WP_001394052.1 F1 capsule-anchoring protein VF
EXA01_RS23995 (39574) 39574..40053 + 480 WP_215250692.1 outer membrane usher CS3-2 domain protein -
EXA01_RS24000 (40075) 40075..40581 + 507 WP_013188494.1 CS3 fimbrial subunit A VF
EXA01_RS25680 (40835) 40835..41227 + 393 WP_000434829.1 IS3 family transposase ISPa31 Transposase
EXA01_RS24010 (41395) 41395..41760 + 366 WP_000124138.1 hypothetical protein -
EXA01_RS24015 (41760) 41760..42592 + 833 Protein_57 IS91 family transposase IS91 Transposase
EXA01_RS24020 (42961) 42961..43758 - 798 WP_000346363.1 CFA/I fimbrial subunit D VF
EXA01_RS24025 (43957) 43957..44150 + 194 Protein_59 ANR family transcriptional regulator -
EXA01_RS24035 (45244) 45244..46076 - 833 Protein_61 IS91 family transposase IS91 Transposase
EXA01_RS24040 (46076) 46076..46441 - 366 WP_000124138.1 hypothetical protein -
EXA01_RS24045 (46488) 46488..47306 + 819 Protein_63 IS630 family transposase -
EXA01_RS24050 (47865) 47865..48995 + 1131 WP_001394310.1 hypothetical protein -
EXA01_RS24055 (48992) 48992..50194 + 1203 WP_000836404.1 TolC family protein -
EXA01_RS24060 (50157) 50157..50924 + 768 WP_001394312.1 hypothetical protein -
EXA01_RS24065 (50917) 50917..51543 + 627 WP_000593828.1 ABC transporter ATP-binding protein -
EXA01_RS24070 (51724) 51724..52886 + 1163 Protein_68 IS3 family transposase ISEc17 Transposase
EXA01_RS24075 (53390) 53390..54624 + 1235 WP_164968891.1 IS3 family transposase IS2 Transposase
EXA01_RS24080 (54765) 54765..55121 + 357 WP_013188496.1 hypothetical protein -
EXA01_RS24085 (55283) 55283..55528 + 246 Protein_71 IS256 family transposase IS1414 Transposase
EXA01_RS24090 (55595) 55595..56758 + 1164 Protein_72 IS3 family transposase ISEc17 Transposase
EXA01_RS24095 (57027) 57027..58271 + 1245 WP_001416764.1 hypothetical protein -
EXA01_RS24100 (58343) 58343..58717 - 375 Protein_74 IS1 family transposase -
EXA01_RS24110 (59960) 59960..60893 - 934 Protein_76 IS91 family transposase ISEc37 Transposase
EXA01_RS24115 (60974) 60974..62146 + 1173 WP_000952425.1 IS21 family transposase ISEc62 Transposase
EXA01_RS24120 (62146) 62146..62940 + 795 WP_000544809.1 IS21 family transposase ISEc62 Transposase
EXA01_RS24125 (63004) 63004..63272 - 269 Protein_79 transposase zinc-binding domain-containing protein -
EXA01_RS24130 (63272) 63272..63637 - 366 WP_000124092.1 hypothetical protein -
EXA01_RS24135 (63719) 63719..64327 + 609 Protein_81 IS3 family transposase IS2 Transposase
EXA01_RS24140 (64530) 64530..66341 + 1812 WP_000260522.1 Heme/hemopexin transporter protein HuxB VF
EXA01_RS24145 (66431) 66431..70981 + 4551 WP_216311696.1 filamentous hemagglutinin N-terminal domain-containing protein -
EXA01_RS24150 (71006) 71006..71191 + 186 WP_000894830.1 hypothetical protein -
EXA01_RS24155 (71263) 71263..73176 + 1914 WP_001393184.1 UDP-glucose:protein N-beta-glucosyltransferase VF
EXA01_RS24160 (73173) 73173..73667 + 495 WP_001203081.1 DUF2919 family protein -
EXA01_RS24165 (73739) 73739..73963 - 225 Protein_87 IS21 family transposase ISEc12 Transposase
EXA01_RS24175 (74230) 74230..74562 - 333 Protein_88 IS256 family transposase IS1414 Transposase
EXA01_RS24180 (74600) 74600..74881 - 282 WP_000780221.1 helix-turn-helix transcriptional regulator -
EXA01_RS24185 (74862) 74862..75191 - 330 WP_000471255.1 type II toxin-antitoxin system RelE/ParE family toxin -
EXA01_RS24190 (75384) 75384..75803 - 420 Protein_91 IS3 family transposase ISBmu11 Transposase
EXA01_RS24195 (76180) 76180..76398 + 219 WP_013188501.1 Heat-stable enterotoxin A3/A4 VF
EXA01_RS24200 (76505) 76505..76755 + 251 Protein_93 IS5 family transposase IS903B Transposase
EXA01_RS24205 (77021) 77021..77215 - 195 Protein_94 transposase domain-containing protein -
EXA01_RS24210 (77276) 77276..78142 + 867 Protein_95 IS110 family transposase ISEc45 Transposase
EXA01_RS24215 (78186) 78186..78659 - 474 Protein_96 IS3 family transposase IS629 Transposase
EXA01_RS24220 (78749) 78749..80257 - 1509 WP_001189123.1 group II intron reverse transcriptase/maturase -
EXA01_RS24225 (80930) 80930..81669 - 740 Protein_98 IS3 family transposase IS629 Transposase
EXA01_RS24230 (81695) 81695..82069 - 375 WP_029238993.1 IS3 family transposase ISCARN101 Transposase
EXA01_RS24235 (82219) 82219..82710 - 492 Protein_100 IS91 family transposase ISSbo1 Transposase
EXA01_RS24240 (82691) 82691..82963 - 273 WP_000019162.1 hypothetical protein -
EXA01_RS24245 (83279) 83279..84055 + 777 WP_001378495.1 Heat-labile enterotoxin A chain VF
EXA01_RS24250 (84052) 84052..84426 + 375 WP_013188479.1 Heat-labile enterotoxin B chain VF
EXA01_RS24255 (84747) 84747..85643 - 897 Protein_104 IS3 family transposase ISSd1 Transposase
EXA01_RS24260 (85650) 85650..86801 - 1152 WP_001254933.1 IS30 family transposase IS30D Transposase
EXA01_RS25685 (86798) 86798..86878 - 81 Protein_106 hypothetical protein -
EXA01_RS24265 (86866) 86866..87222 + 357 Protein_107 IS3 family transposase IS911 Transposase
EXA01_RS24270 (87297) 87297..89264 + 1968 Protein_108 ParB/RepB/Spo0J family partition protein -
EXA01_RS24275 (89319) 89319..89753 + 435 WP_000845954.1 conjugation system SOS inhibitor PsiB -
EXA01_RS24280 (89750) 89750..90509 + 760 Protein_110 plasmid SOS inhibition protein A -
- (90481) 90481..90675 + 195 NuclAT_1 - -
- (90481) 90481..90675 + 195 NuclAT_1 - -
- (90481) 90481..90675 + 195 NuclAT_1 - -
- (90481) 90481..90675 + 195 NuclAT_1 - -
EXA01_RS25690 (90682) 90682..90831 + 150 Protein_111 plasmid maintenance protein Mok -
EXA01_RS24285 (90782) 90782..90898 + 117 WP_001323520.1 type I toxin-antitoxin system Hok family toxin -
EXA01_RS24290 (91136) 91136..91496 - 361 Protein_113 hypothetical protein -
EXA01_RS24295 (91813) 91813..92115 + 303 WP_001272235.1 hypothetical protein -
EXA01_RS24300 (92271) 92271..92558 + 288 WP_000107522.1 hypothetical protein -
EXA01_RS24305 (92674) 92674..93495 + 822 WP_001393327.1 DUF932 domain-containing protein -
EXA01_RS24310 (93791) 93791..94384 - 594 WP_077825896.1 hypothetical protein VF
EXA01_RS24315 (94716) 94716..95099 + 384 WP_000124827.1 conjugal transfer relaxosome DNA-binding protein TraM -
EXA01_RS24320 (95293) 95293..95964 + 672 WP_000283565.1 conjugal transfer transcriptional regulator TraJ -
EXA01_RS24325 (96101) 96101..96328 + 228 WP_000089263.1 conjugal transfer relaxosome protein TraY -
EXA01_RS24330 (96361) 96361..96723 + 363 WP_001098998.1 type IV conjugative transfer system pilin TraA -
EXA01_RS24335 (96728) 96728..97039 + 312 WP_000012113.1 type IV conjugative transfer system protein TraL -
EXA01_RS24340 (97061) 97061..97627 + 567 WP_000399782.1 type IV conjugative transfer system protein TraE -
EXA01_RS24345 (97614) 97614..98341 + 728 Protein_124 type-F conjugative transfer system secretin TraK -
EXA01_RS24350 (98494) 98494..98823 + 330 Protein_125 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
EXA01_RS24355 (98813) 98813..99127 + 315 WP_001417954.1 P-type conjugative transfer protein TrbJ -
EXA01_RS24360 (99081) 99081..99473 + 393 WP_000138370.1 F-type conjugal transfer protein TrbF -
EXA01_RS24365 (99460) 99460..100545 + 1086 Protein_128 conjugal transfer protein TraH -
EXA01_RS24370 (100572) 100572..103340 + 2769 WP_032323087.1 conjugal transfer mating-pair stabilization protein TraG -
EXA01_RS24375 (103373) 103373..103894 + 522 WP_000632667.1 conjugal transfer entry exclusion protein TraS -
EXA01_RS24380 (103940) 103940..104650 + 711 WP_240532620.1 conjugal transfer complement resistance protein TraT -
EXA01_RS24385 (104853) 104853..105590 + 738 WP_000199908.1 hypothetical protein -
EXA01_RS24390 (105675) 105675..106025 - 351 Protein_133 IS21 family transposase IS100kyp Transposase
EXA01_RS24395 (106019) 106019..106459 - 441 Protein_134 IS21 family transposase IS100kyp Transposase
EXA01_RS24400 (106583) 106583..108745 + 2163 WP_086405440.1 type IV conjugative transfer system coupling protein TraD -
EXA01_RS24405 (108745) 108745..109233 + 489 Protein_136 Multifunctional conjugation protein TraI Relaxase
EXA01_RS24410 (109228) 109228..109368 + 141 Protein_137 Multifunctional conjugation protein TraI Relaxase
EXA01_RS24415 (109427) 109427..110287 + 861 WP_000704511.1 putative protein YcjY VF
EXA01_RS24420 (110390) 110390..110950 + 561 WP_000840475.1 fertility inhibition protein FinO -
EXA01_RS25695 (111081) 111081..111194 + 114 Protein_140 hypothetical protein -
EXA01_RS24425 (111247) 111247..111924 + 678 WP_001704819.1 IS66 family transposase ISCro1 Transposase
EXA01_RS24430 (111924) 111924..112271 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
EXA01_RS24435 (112463) 112463..113053 + 591 Protein_143 IS66 family transposase ISCro1 Transposase
EXA01_RS24440 (113600) 113600..114226 + 627 WP_001393151.1 NYN domain-containing protein -
EXA01_RS24445 (114378) 114378..114968 + 591 WP_001393319.1 DUF2726 domain-containing protein -
EXA01_RS24450 (115208) 115208..115462 + 255 WP_000083830.1 replication regulatory protein RepA -
EXA01_RS24455 (115699) 115699..115773 + 75 WP_001365705.1 RepA leader peptide Tap -
EXA01_RS24460 (115766) 115766..116623 + 858 WP_000130971.1 incFII family plasmid replication initiator RepA -
EXA01_RS24465 (117594) 117594..117905 + 312 WP_000483538.1 type II toxin-antitoxin system RelE/ParE family toxin -
EXA01_RS24470 (117905) 117905..118192 + 288 WP_000865086.1 helix-turn-helix transcriptional regulator -
EXA01_RS24475 (118569) 118569..119078 + 510 WP_000115001.1 peptide deformylase -
EXA01_RS24480 (119093) 119093..119194 + 102 Protein_152 methionyl-tRNA formyltransferase -
EXA01_RS24485 (119383) 119383..119601 - 219 Protein_153 IS91 family transposase ISEc37 Transposase
EXA01_RS24490 (119688) 119688..119933 + 246 Protein_154 IS630 family transposase -
EXA01_RS24495 (119995) 119995..120939 - 945 WP_001420717.1 Lipid A biosynthesis myristoyltransferase 2 VF
EXA01_RS24500 (121004) 121004..121954 - 951 WP_001528378.1 virulence factor VirK -
EXA01_RS24505 (121959) 121959..123047 - 1089 WP_001528375.1 putative hexosyltransferase CapU -
EXA01_RS24510 (123050) 123050..123892 - 843 WP_162749921.1 polysaccharide deacetylase family protein -
EXA01_RS24515 (124136) 124136..124678 - 543 WP_000194543.1 hypothetical protein -
EXA01_RS24520 (124678) 124678..124935 - 258 WP_000343093.1 hypothetical protein -
EXA01_RS24525 (125380) 125380..125598 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
EXA01_RS24530 (125600) 125600..125905 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
EXA01_RS24535 (125930) 125930..126619 + 690 Protein_163 site-specific integrase -
EXA01_RS24540 (126949) 126949..127590 + 642 WP_000470631.1 Tn3 family transposase TnpR_TnEc1 Transposase
EXA01_RS24545 (128030) 128030..128710 - 681 WP_000452091.1 EAL domain-containing protein -
EXA01_RS24550 (128958) 128958..129661 + 704 Protein_166 helix-turn-helix domain-containing protein -
EXA01_RS24555 (130004) 130004..134098 - 4095 WP_001394776.1 Serine protease EatA VF
EXA01_RS24560 (134864) 134864..135225 - 362 Protein_168 Tn3 family transposase -
EXA01_RS24565 (135326) 135326..135565 + 240 WP_001355715.1 IS3 family transposase ISBope1 Transposase
EXA01_RS24570 (135594) 135594..136291 + 698 Protein_170 IS1 family transposase -
EXA01_RS24575 (136264) 136264..136404 + 141 Protein_171 IS3 family transposase -
EXA01_RS24580 (136566) 136566..137360 - 795 WP_000544809.1 IS21 family transposase ISEc62 Transposase
EXA01_RS24585 (137360) 137360..138532 - 1173 WP_000952425.1 IS21 family transposase ISEc62 Transposase
EXA01_RS25700 (138573) 138573..139034 + 462 WP_000900405.1 hypothetical protein -
EXA01_RS24595 (139102) 139102..139209 - 108 WP_253207249.1 hypothetical protein -
EXA01_RS24600 (139423) 139423..140403 + 981 WP_001218105.1 plasmid segregation protein ParM -
EXA01_RS24605 (140406) 140406..140828 + 423 WP_000774834.1 plasmid partitioning/stability family protein -
EXA01_RS24610 (140852) 140852..141142 + 291 WP_061092123.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance