MGE detailed information
MGE type: Mobilizable plasmid MGE length: 112467 bp
Accession: NZ_CP028796 Location: 1..112467 Organism: Klebsiella pneumoniae strain WCHKP040035 Replicon: plasmid pKPC2_040035
Accession: NZ_CP028796 Location: 1..112467 Organism: Klebsiella pneumoniae strain WCHKP040035 Replicon: plasmid pKPC2_040035
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6M51_RS00345 () | 1221..1607 | + | 387 | WP_012311408.1 | hypothetical protein | - |
| C6M51_RS00350 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| C6M51_RS00355 () | 2670..3134 | + | 465 | WP_012602143.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| C6M51_RS00360 () | 3131..3235 | + | 105 | WP_012602142.1 | hypothetical protein | - |
| C6M51_RS00365 () | 3328..3426 | + | 99 | Protein_6 | glycosyltransferase | - |
| C6M51_RS00370 () | 3383..3798 | + | 416 | Protein_7 | IS1 family transposase IS1R | Transposase |
| C6M51_RS00375 () | 3834..4379 | - | 546 | Protein_8 | Tn3 family transposase TnpA_Tn3 | Transposase |
| C6M51_RS00380 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS00385 () | 5219..5410 | + | 192 | Protein_10 | IS1380 family transposase | - |
| C6M51_RS00390 () | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| C6M51_RS00395 () | 6615..7538 | + | 924 | WP_012579081.1 | IS5 family transposase IS903B | Transposase |
| C6M51_RS00400 () | 7595..8692 | + | 1098 | Protein_13 | TonB-dependent receptor | - |
| C6M51_RS00405 () | 8760..9209 | - | 450 | Protein_14 | chemotaxis protein | - |
| C6M51_RS00410 () | 9230..9343 | + | 114 | Protein_15 | integrase | - |
| C6M51_RS00415 () | 9289..9993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS00420 () | 10193..10282 | + | 90 | Protein_17 | recombinase | - |
| C6M51_RS00425 () | 10449..11039 | - | 591 | Protein_18 | IS91 family transposase ISSbo1 | Transposase |
| C6M51_RS00430 () | 11104..11808 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS00435 () | 11859..12476 | - | 618 | Protein_20 | IS91 family transposase ISSbo1 | Transposase |
| C6M51_RS00440 () | 12486..12674 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| C6M51_RS00445 () | 12766..13302 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| C6M51_RS00450 () | 13485..14345 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| C6M51_RS00455 () | 14515..15270 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| C6M51_RS00460 () | 15351..15668 | - | 318 | Protein_25 | sodium:proton antiporter | - |
| C6M51_RS00465 () | 15720..16424 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS00470 () | 16415..16555 | + | 141 | WP_071557810.1 | hypothetical protein | - |
| C6M51_RS00475 () | 16571..17068 | + | 498 | Protein_28 | hypothetical protein | - |
| C6M51_RS00480 () | 17346..17477 | - | 132 | Protein_29 | transposase | - |
| C6M51_RS00485 () | 18004..18238 | + | 235 | Protein_30 | plasmid stabilization protein | - |
| C6M51_RS00490 () | 18366..18647 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| C6M51_RS00495 () | 18770..19120 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| C6M51_RS00500 () | 19123..20085 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| C6M51_RS00505 () | 20232..20525 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| C6M51_RS00510 () | 20466..20645 | - | 180 | WP_072109530.1 | hypothetical protein | - |
| C6M51_RS00515 () | 20602..21285 | + | 684 | WP_000085883.1 | DNA methylase | - |
| C6M51_RS00520 () | 21286..21507 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| C6M51_RS00525 () | 21521..21955 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| C6M51_RS00530 () | 22006..22231 | + | 226 | Protein_39 | hypothetical protein | - |
| C6M51_RS00535 () | 22655..23227 | + | 573 | WP_011161242.1 | YubH family protein | - |
| C6M51_RS00540 () | 23200..23625 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| C6M51_RS00545 () | 23672..24094 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| C6M51_RS00550 () | 24091..24282 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| C6M51_RS00555 () | 24596..26263 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| C6M51_RS00560 () | 27143..27400 | - | 258 | WP_015059006.1 | hypothetical protein | - |
| C6M51_RS00565 () | 27663..27893 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| C6M51_RS00570 () | 27945..29306 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| C6M51_RS00575 () | 29353..29916 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| C6M51_RS00580 () | 29827..30021 | - | 195 | WP_071528982.1 | hypothetical protein | - |
| C6M51_RS00585 () | 30002..30463 | - | 462 | WP_001479900.1 | hypothetical protein | - |
| C6M51_RS00590 () | 30620..30739 | + | 120 | WP_001127499.1 | hypothetical protein | - |
| C6M51_RS00595 () | 30726..31292 | + | 567 | WP_010891337.1 | single-stranded DNA-binding protein | - |
| C6M51_RS00600 () | 31350..31583 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| C6M51_RS00605 () | 31644..33667 | + | 2024 | Protein_54 | hypothetical protein | - |
| C6M51_RS00610 () | 33736..34170 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| C6M51_RS00615 () | 34167..34886 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 34898..35122 | + | 225 | NuclAT_0 | - | - |
| - () | 34898..35122 | + | 225 | NuclAT_0 | - | - |
| - () | 34898..35122 | + | 225 | NuclAT_0 | - | - |
| - () | 34898..35122 | + | 225 | NuclAT_0 | - | - |
| C6M51_RS00620 () | 35020..35324 | + | 305 | Protein_57 | type I toxin-antitoxin system hok family toxin | - |
| C6M51_RS00625 () | 35547..35765 | + | 219 | WP_001309236.1 | hypothetical protein | - |
| C6M51_RS00630 () | 35781..36013 | + | 233 | Protein_59 | hypothetical protein | - |
| C6M51_RS00635 () | 35940..36176 | - | 237 | WP_012881134.1 | hypothetical protein | - |
| C6M51_RS00640 () | 36239..36535 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| C6M51_RS00645 () | 36616..37467 | + | 852 | WP_085959725.1 | DUF945 domain-containing protein | - |
| C6M51_RS00650 () | 37764..38411 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| C6M51_RS00655 () | 38688..39071 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| C6M51_RS00660 () | 39202..39948 | + | 747 | WP_077249350.1 | PAS domain-containing protein | - |
| C6M51_RS00665 () | 40042..40269 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| C6M51_RS00670 () | 40303..40668 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| C6M51_RS00675 () | 40683..40994 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| C6M51_RS00680 () | 41016..41582 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| C6M51_RS00685 () | 41626..42297 | + | 672 | WP_001340581.1 | type-F conjugative transfer system secretin TraK | - |
| C6M51_RS00690 () | 42297..42554 | + | 258 | WP_101307356.1 | IS6 family transposase IS15 | Transposase |
| C6M51_RS00695 () | 42566..43270 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS00700 () | 43333..43647 | - | 315 | Protein_73 | hypothetical protein | - |
| C6M51_RS00705 () | 43640..44892 | - | 1253 | Protein_74 | four-carbon acid sugar kinase family protein | - |
| C6M51_RS00710 () | 44904..45806 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| C6M51_RS00715 () | 46067..46828 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| C6M51_RS00720 () | 46849..47709 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| C6M51_RS00725 () | 47630..47869 | - | 240 | WP_099093179.1 | hypothetical protein | - |
| C6M51_RS00730 () | 47950..49848 | - | 1899 | Protein_79 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| C6M51_RS00735 () | 49914..50618 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS00740 () | 50564..50734 | - | 171 | Protein_81 | adenine-specific DNA-methyltransferase | - |
| C6M51_RS00745 () | 50658..51131 | + | 474 | WP_014343468.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| C6M51_RS00750 () | 51254..52234 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| C6M51_RS00755 () | 52510..53391 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| C6M51_RS00760 () | 53641..54522 | - | 882 | Protein_85 | IS1182 family transposase ISKpn6 | Transposase |
| C6M51_RS00765 () | 54626..54922 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
| C6M51_RS00770 () | 55251..55676 | - | 426 | WP_013213989.1 | antirestriction protein | - |
| C6M51_RS00775 () | 55787..56065 | - | 279 | WP_013213990.1 | hypothetical protein | - |
| C6M51_RS00780 () | 56599..57216 | - | 618 | Protein_89 | replication protein | - |
| C6M51_RS00785 () | 57608..58168 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| C6M51_RS00790 () | 58172..59245 | + | 1074 | Protein_91 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| C6M51_RS00795 () | 59233..59352 | + | 120 | Protein_92 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| C6M51_RS00800 () | 59298..60002 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS00805 () | 60067..61275 | - | 1209 | Protein_94 | transposase | - |
| C6M51_RS00810 () | 61207..61380 | + | 174 | Protein_95 | resolvase | - |
| C6M51_RS00815 () | 61314..62021 | - | 708 | WP_000204520.1 | putative signaling protein | VF |
| C6M51_RS00820 () | 62018..62254 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| C6M51_RS00825 () | 62251..62613 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| C6M51_RS00830 () | 62631..64325 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| C6M51_RS00835 () | 64377..64799 | - | 423 | WP_107331976.1 | organomercurial transporter MerC | - |
| C6M51_RS00840 () | 64835..65110 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| C6M51_RS00845 () | 65124..65474 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| C6M51_RS00850 () | 65546..65980 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| C6M51_RS00855 () | 66059..67063 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| C6M51_RS00860 () | 67343..67615 | - | 273 | Protein_105 | IS5 family transposase ISPan1 | Transposase |
| C6M51_RS00865 () | 67644..68341 | - | 698 | Protein_106 | IS1 family transposase ISKpn14 | Transposase |
| C6M51_RS00870 () | 68597..69619 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| C6M51_RS00875 () | 69604..71166 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| C6M51_RS00880 () | 71240..71656 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| C6M51_RS00885 () | 71653..71883 | - | 231 | WP_001261282.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| C6M51_RS00890 () | 71867..72301 | + | 435 | WP_015493090.1 | hypothetical protein | - |
| C6M51_RS00895 () | 72462..73406 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| C6M51_RS00900 () | 73485..73835 | + | 351 | WP_032738650.1 | hypothetical protein | - |
| C6M51_RS00905 () | 73893..74414 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| C6M51_RS00910 () | 74460..74663 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| C6M51_RS00915 () | 74693..75697 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| C6M51_RS00920 () | 75881..76660 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| C6M51_RS00925 () | 76706..76963 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| C6M51_RS00930 () | 77741..78607 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| C6M51_RS00935 () | 79037..79303 | - | 267 | Protein_120 | hypothetical protein | - |
| C6M51_RS00940 () | 79717..80922 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| C6M51_RS00945 () | 80919..81896 | + | 978 | WP_086523286.1 | ParB/RepB/Spo0J family partition protein | - |
| C6M51_RS00950 () | 81978..83249 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| C6M51_RS00955 () | 83249..83680 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| C6M51_RS00960 () | 83839..84090 | + | 252 | WP_009483812.1 | hypothetical protein | - |
| C6M51_RS00965 () | 84090..85574 | + | 1485 | WP_004152765.1 | group II intron reverse transcriptase/maturase | - |
| C6M51_RS00970 () | 85823..86794 | + | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| C6M51_RS00975 () | 86797..87468 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| C6M51_RS00980 () | 87531..87761 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| C6M51_RS00985 () | 88198..88899 | + | 702 | WP_001568041.1 | DNA methylase | - |
| C6M51_RS00990 () | 88899..89120 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| C6M51_RS00995 () | 89130..89549 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| C6M51_RS01000 () | 89603..90370 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| C6M51_RS01005 () | 91051..91479 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| C6M51_RS01010 () | 91522..92028 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| C6M51_RS01015 () | 92071..92262 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| C6M51_RS01020 () | 92450..92704 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| C6M51_RS01025 () | 92739..93059 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| C6M51_RS01030 () | 93091..93195 | + | 105 | Protein_139 | DNA polymerase III subunit theta | - |
| C6M51_RS01035 () | 93428..93647 | - | 220 | Protein_140 | hypothetical protein | - |
| C6M51_RS01040 () | 93631..93720 | + | 90 | WP_099130656.1 | single-stranded DNA-binding protein | - |
| C6M51_RS01045 () | 93739..93966 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| C6M51_RS01050 () | 94058..94288 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| C6M51_RS01055 () | 94340..95695 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| C6M51_RS01060 () | 95743..96306 | + | 564 | WP_014343514.1 | methyltransferase | - |
| C6M51_RS01065 () | 96201..96521 | - | 321 | WP_004161756.1 | hypothetical protein | - |
| C6M51_RS01070 () | 96640..96901 | - | 262 | Protein_147 | hypothetical protein | - |
| C6M51_RS01075 () | 96816..97035 | - | 220 | Protein_148 | hypothetical protein | - |
| C6M51_RS01080 () | 97139..97681 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| C6M51_RS01085 () | 97730..97978 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| C6M51_RS01090 () | 98048..100105 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| C6M51_RS01095 () | 100150..100581 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| C6M51_RS01100 () | 100578..101306 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| C6M51_RS01105 () | 101303..101629 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| C6M51_RS01110 () | 101685..102059 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| C6M51_RS01115 () | 102120..102230 | - | 111 | Protein_156 | protein sok | - |
| C6M51_RS01120 () | 102287..102445 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| C6M51_RS01125 () | 103138..103410 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| C6M51_RS01130 () | 103407..103757 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| C6M51_RS01135 () | 103772..104089 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| C6M51_RS01140 () | 104487..104756 | - | 270 | Protein_161 | hypothetical protein | - |
| C6M51_RS01145 () | 104930..105286 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| C6M51_RS01150 () | 105347..105559 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| C6M51_RS01155 () | 105570..105794 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| C6M51_RS01160 () | 105875..106195 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| C6M51_RS01165 () | 106185..106463 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| C6M51_RS01170 () | 106467..106571 | + | 105 | Protein_167 | transcriptional regulator | - |
| C6M51_RS01175 () | 106594..106791 | - | 198 | Protein_168 | hypothetical protein | - |
| C6M51_RS01180 () | 107149..107853 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C6M51_RS01185 () | 107917..108078 | + | 162 | Protein_170 | DNA helicase | - |
| C6M51_RS01190 () | 108098..108844 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| C6M51_RS01195 () | 108899..109459 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| C6M51_RS01200 () | 109591..109791 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| C6M51_RS01205 () | 110177..110776 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| C6M51_RS01210 () | 110940..111170 | + | 231 | WP_001736714.1 | hypothetical protein | - |
| C6M51_RS01215 () | 111193..111420 | - | 228 | Protein_176 | hypothetical protein | - |
| - () | 111371..111430 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 111371..111430 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 111371..111430 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 111371..111430 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| C6M51_RS01220 () | 111475..111624 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| C6M51_RS01225 () | 111908..112156 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| C6M51_RS01230 () | 112157..112366 | - | 210 | WP_064765370.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|