MGE detailed information
MGE type: Conjugative plasmid MGE length: 107188 bp
Accession: NZ_CP027439 Location: 1..107188 Organism: Escherichia coli strain 2012C-4221 Replicon: plasmid unnamed2
Accession: NZ_CP027439 Location: 1..107188 Organism: Escherichia coli strain 2012C-4221 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6W65_RS25975 () | 2032..2925 | - | 894 | WP_106907053.1 | HTH-type transcriptional regulator PgrR | VF |
| C6W65_RS25980 () | 3068..3838 | + | 771 | WP_106907055.1 | SDR family oxidoreductase | - |
| C6W65_RS25985 () | 3881..4936 | - | 1056 | WP_106907163.1 | NAD(P)-dependent alcohol dehydrogenase | - |
| C6W65_RS25990 () | 5014..5403 | - | 390 | Protein_4 | D-threitol dehydrogenase | VF |
| C6W65_RS25995 () | 5575..6273 | - | 699 | Protein_5 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| C6W65_RS26000 () | 6366..7193 | - | 828 | WP_106907057.1 | SDR family oxidoreductase | - |
| C6W65_RS26005 () | 7260..8408 | - | 1149 | WP_106907059.1 | iron-containing alcohol dehydrogenase | - |
| C6W65_RS26010 () | 8542..9498 | + | 957 | WP_199851544.1 | HTH-type transcriptional regulator DmlR | VF |
| C6W65_RS26015 () | 9824..10600 | - | 777 | WP_106907061.1 | NAD-dependent glycerol dehydrogenase | VF |
| C6W65_RS26020 () | 10631..10924 | - | 294 | WP_106907063.1 | Dabb family protein | - |
| C6W65_RS26025 () | 10936..11997 | - | 1062 | WP_106907065.1 | NAD(P)-dependent alcohol dehydrogenase | - |
| C6W65_RS26030 () | 12146..13105 | + | 960 | WP_106907067.1 | HTH-type transcriptional regulator DmlR | VF |
| C6W65_RS26035 () | 13741..14070 | + | 330 | WP_000344277.1 | hypothetical protein | - |
| C6W65_RS26040 () | 14109..14579 | + | 471 | Protein_14 | hypothetical protein | - |
| C6W65_RS26045 () | 14618..15831 | + | 1214 | WP_106907069.1 | IS3 family transposase ISCfr6 | Transposase |
| C6W65_RS26055 () | 16087..16521 | + | 435 | WP_000429590.1 | hypothetical protein | - |
| C6W65_RS26060 () | 16518..17300 | + | 783 | WP_001418814.1 | site-specific integrase | - |
| C6W65_RS26065 () | 18130..18441 | + | 312 | WP_078405668.1 | hypothetical protein | - |
| C6W65_RS26070 () | 18602..19003 | + | 402 | WP_000171282.1 | hypothetical protein | - |
| C6W65_RS27080 () | 19121..19450 | + | 330 | WP_001334906.1 | hypothetical protein | - |
| C6W65_RS26080 () | 19646..19903 | + | 258 | WP_106907072.1 | hypothetical protein | - |
| C6W65_RS26085 () | 19999..20445 | - | 447 | WP_000616196.1 | hypothetical protein | - |
| C6W65_RS26090 () | 20563..21042 | + | 480 | WP_106907074.1 | peptidase M14 | - |
| C6W65_RS26095 () | 21294..21491 | + | 198 | WP_077631139.1 | AraC family transcriptional regulator | - |
| C6W65_RS26100 () | 21654..21941 | - | 288 | WP_000222786.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| C6W65_RS26105 () | 21938..22189 | - | 252 | WP_001120171.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| C6W65_RS26110 () | 22413..22952 | + | 540 | WP_106907077.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| C6W65_RS26115 () | 23338..24204 | + | 867 | WP_000172786.1 | AAA family ATPase | - |
| C6W65_RS26120 () | 24204..25235 | + | 1032 | WP_106907079.1 | ParB/RepB/Spo0J family partition protein | - |
| C6W65_RS26125 () | 25235..25672 | + | 438 | WP_000843285.1 | hypothetical protein | - |
| C6W65_RS26970 () | 25669..25992 | + | 324 | WP_153645668.1 | hypothetical protein | - |
| C6W65_RS26135 () | 26075..27349 | - | 1275 | WP_106907081.1 | Y-family DNA polymerase | - |
| C6W65_RS26140 () | 27349..27771 | - | 423 | WP_047089913.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| C6W65_RS26145 () | 28252..29139 | + | 888 | WP_000066222.1 | RepB family plasmid replication initiator protein | - |
| C6W65_RS27085 () | 29684..29986 | + | 303 | WP_199851545.1 | antirestriction protein | - |
| C6W65_RS26160 () | 30033..30455 | + | 423 | WP_106907019.1 | DUF1380 family protein | - |
| C6W65_RS26165 () | 30452..30643 | + | 192 | WP_106907018.1 | hypothetical protein | - |
| C6W65_RS26180 () | 31626..31856 | + | 231 | WP_106907084.1 | hypothetical protein | - |
| C6W65_RS26185 () | 31908..33269 | + | 1362 | WP_106907086.1 | DUF3560 domain-containing protein | - |
| C6W65_RS26190 () | 33316..33879 | + | 564 | WP_001346267.1 | class I SAM-dependent methyltransferase | - |
| C6W65_RS26195 () | 33965..34427 | - | 463 | Protein_41 | hypothetical protein | - |
| C6W65_RS27090 () | 34497..34703 | + | 207 | WP_000275848.1 | hypothetical protein | - |
| C6W65_RS26210 () | 34729..35262 | + | 534 | WP_106907088.1 | single-stranded DNA-binding protein | - |
| C6W65_RS26215 () | 35325..35558 | + | 234 | WP_021564200.1 | DUF905 family protein | - |
| C6W65_RS26220 () | 35622..37580 | + | 1959 | WP_106907090.1 | ParB/RepB/Spo0J family partition protein | - |
| C6W65_RS26225 () | 37635..38069 | + | 435 | WP_000845926.1 | conjugation system SOS inhibitor PsiB | - |
| C6W65_RS26230 () | 38066..38785 | + | 720 | WP_106907092.1 | plasmid SOS inhibition protein A | - |
| - () | 38797..39021 | + | 225 | NuclAT_0 | - | - |
| - () | 38797..39021 | + | 225 | NuclAT_0 | - | - |
| - () | 38797..39021 | + | 225 | NuclAT_0 | - | - |
| - () | 38797..39021 | + | 225 | NuclAT_0 | - | - |
| - () | 38954..39019 | + | 66 | - | - | Antitoxin Detail |
| C6W65_RS26240 () | 39065..39223 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| C6W65_RS27095 () | 39577..39789 | - | 213 | WP_162491396.1 | hypothetical protein | - |
| C6W65_RS26260 () | 40138..40425 | + | 288 | WP_000107538.1 | hypothetical protein | - |
| C6W65_RS26265 () | 40543..41364 | + | 822 | WP_158709101.1 | DUF945 domain-containing protein | - |
| C6W65_RS26270 () | 41661..42251 | - | 591 | WP_168926342.1 | hypothetical protein | VF |
| C6W65_RS26275 () | 42540..42923 | + | 384 | WP_046788507.1 | relaxosome protein TraM | - |
| C6W65_RS26280 () | 43110..43799 | + | 690 | WP_000283380.1 | conjugal transfer transcriptional regulator TraJ | - |
| C6W65_RS26285 () | 43898..44293 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| C6W65_RS26290 () | 44326..44685 | + | 360 | WP_000994781.1 | type IV conjugative transfer system pilin TraA | - |
| C6W65_RS26295 () | 44700..45011 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| C6W65_RS26300 () | 45033..45599 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| C6W65_RS26305 () | 45610..46314 | + | 705 | WP_158709102.1 | type-F conjugative transfer system secretin TraK | - |
| C6W65_RS26310 () | 46314..47741 | + | 1428 | WP_106907096.1 | conjugal transfer protein TraB | - |
| C6W65_RS26315 () | 47731..48318 | + | 588 | WP_106907098.1 | conjugal transfer protein TraP | - |
| C6W65_RS26320 () | 48272..48625 | + | 354 | WP_087906540.1 | conjugal transfer protein TrbD | - |
| C6W65_RS26325 () | 48618..48869 | + | 252 | WP_023181039.1 | conjugal transfer protein TrbG | - |
| C6W65_RS26330 () | 48866..49381 | + | 516 | WP_097749533.1 | type IV conjugative transfer system lipoprotein TraV | - |
| C6W65_RS26335 () | 49516..49737 | + | 222 | WP_106907100.1 | conjugal transfer protein TraR | - |
| C6W65_RS26340 () | 49730..50203 | + | 474 | WP_158709098.1 | hypothetical protein | - |
| C6W65_RS26980 () | 50528..50890 | + | 363 | WP_029400175.1 | hypothetical protein | - |
| C6W65_RS26355 () | 51016..53646 | + | 2631 | WP_106907105.1 | type IV secretion system protein TraC | - |
| C6W65_RS26360 () | 53643..54029 | + | 387 | WP_106907107.1 | type-F conjugative transfer system protein TrbI | - |
| C6W65_RS26365 () | 54026..54658 | + | 633 | WP_106907109.1 | type-F conjugative transfer system protein TraW | - |
| C6W65_RS26370 () | 54655..55647 | + | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| C6W65_RS26375 () | 55656..56294 | + | 639 | WP_106907112.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| C6W65_RS26380 () | 56291..58099 | + | 1809 | WP_106907114.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| C6W65_RS26385 () | 58126..58383 | + | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| C6W65_RS26390 () | 58376..59119 | + | 744 | WP_158709099.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| C6W65_RS26395 () | 59135..59482 | + | 348 | WP_106907118.1 | conjugal transfer protein TrbA | - |
| C6W65_RS26400 () | 59601..59885 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C6W65_RS26405 () | 59872..60417 | + | 546 | WP_106907120.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C6W65_RS26410 () | 60347..60709 | + | 363 | WP_011251381.1 | P-type conjugative transfer protein TrbJ | - |
| C6W65_RS26415 () | 60709..62082 | + | 1374 | WP_001137358.1 | conjugal transfer protein TraH | - |
| C6W65_RS26420 () | 62079..64904 | + | 2826 | WP_001007030.1 | conjugal transfer mating pair stabilization protein TraG | - |
| C6W65_RS26425 () | 64901..65410 | + | 510 | WP_106907123.1 | conjugal transfer entry exclusion protein TraS | - |
| C6W65_RS26430 () | 65424..66155 | + | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| C6W65_RS26435 () | 66408..68570 | + | 2163 | WP_052944470.1 | type IV conjugative transfer system coupling protein TraD | - |
| C6W65_RS26440 () | 68570..73840 | + | 5271 | WP_106907125.1 | Multifunctional conjugation protein TraI | Relaxase |
| C6W65_RS26445 () | 73860..74606 | + | 747 | WP_050947963.1 | conjugal transfer pilus acetylase TraX | - |
| C6W65_RS26450 () | 74661..75221 | + | 561 | WP_033803061.1 | fertility inhibition protein FinO | - |
| C6W65_RS26455 () | 75357..75569 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| C6W65_RS26460 () | 75815..76276 | + | 462 | WP_106907127.1 | thermonuclease family protein | - |
| C6W65_RS26465 () | 76322..76531 | + | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| C6W65_RS26470 () | 76570..77160 | + | 591 | WP_024228807.1 | DUF2726 domain-containing protein | - |
| C6W65_RS26475 () | 77400..77660 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| C6W65_RS26485 () | 77884..77958 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| C6W65_RS26490 () | 77951..78808 | + | 858 | WP_000130961.1 | incFII family plasmid replication initiator RepA | - |
| C6W65_RS27100 () | 79512..79670 | + | 159 | WP_062873149.1 | hypothetical protein | - |
| C6W65_RS26505 () | 79725..79994 | + | 270 | WP_048889353.1 | hypothetical protein | - |
| C6W65_RS26510 () | 80018..80149 | + | 132 | Protein_97 | 3'-5' exonuclease | - |
| C6W65_RS26515 () | 80110..80568 | + | 459 | WP_106907169.1 | hypothetical protein | - |
| C6W65_RS26520 () | 81272..82045 | - | 774 | WP_106907131.1 | tannase/feruloyl esterase family alpha/beta hydrolase | - |
| C6W65_RS26525 () | 82211..82756 | - | 546 | WP_106907133.1 | isopentenyl-diphosphate Delta-isomerase | - |
| C6W65_RS26530 () | 82850..83566 | - | 717 | WP_106907135.1 | DUF554 domain-containing protein | - |
| C6W65_RS26535 () | 83584..84153 | - | 570 | WP_106907171.1 | UbiX family flavin prenyltransferase | - |
| C6W65_RS26540 () | 84179..85651 | - | 1473 | WP_106907137.1 | UbiD family decarboxylase | - |
| C6W65_RS26545 () | 85817..86761 | + | 945 | WP_106907173.1 | LysR family transcriptional regulator | - |
| C6W65_RS26550 () | 86893..87339 | + | 447 | WP_096959008.1 | YhbP family protein | - |
| C6W65_RS26555 () | 87761..88923 | + | 1163 | Protein_106 | IS3 family transposase ISEal1 | Transposase |
| C6W65_RS26560 () | 89652..90203 | + | 552 | WP_096037716.1 | hypothetical protein | VF |
| C6W65_RS26565 () | 90276..91076 | - | 801 | WP_106907139.1 | Outer membrane protein A | VF |
| C6W65_RS26570 () | 91110..93008 | - | 1899 | WP_158709100.1 | Autotransporter adhesin SadA | VF |
| C6W65_RS26575 () | 94058..94228 | + | 171 | WP_106907143.1 | ESPR domain-containing protein | - |
| C6W65_RS26580 () | 94281..94616 | + | 336 | WP_106907145.1 | Serine protease pic autotransporter | VF |
| C6W65_RS26585 () | 94705..95148 | + | 444 | WP_106907147.1 | hypothetical protein | - |
| C6W65_RS27105 () | 95159..95365 | + | 207 | WP_106907149.1 | Serine protease pic autotransporter | VF |
| C6W65_RS26595 () | 95313..95828 | + | 516 | WP_199851543.1 | Serine protease pic autotransporter | VF |
| C6W65_RS26600 () | 96838..96957 | - | 120 | Protein_115 | hypothetical protein | - |
| C6W65_RS26605 () | 97384..97641 | + | 258 | Protein_116 | hypothetical protein | - |
| C6W65_RS26610 () | 97606..97893 | - | 288 | WP_106907153.1 | NAD(P)H-binding protein | - |
| C6W65_RS26615 () | 98139..99332 | + | 1194 | WP_106907176.1 | multidrug effflux MFS transporter | - |
| C6W65_RS26620 () | 99489..99968 | + | 480 | Protein_119 | cupin domain-containing protein | - |
| C6W65_RS26625 () | 99946..100707 | + | 762 | WP_047626660.1 | carboxymuconolactone decarboxylase family protein | - |
| C6W65_RS26630 () | 100717..101301 | + | 585 | WP_106907155.1 | flavodoxin | - |
| C6W65_RS26635 () | 101410..102168 | + | 759 | Protein_122 | alpha/beta fold hydrolase | - |
| C6W65_RS26640 () | 102171..102793 | + | 623 | Protein_123 | aldo/keto reductase | - |
| C6W65_RS26645 () | 102860..103909 | + | 1050 | WP_106907157.1 | NAD(P)-dependent alcohol dehydrogenase | - |
| C6W65_RS26650 () | 104181..104435 | + | 255 | WP_106907159.1 | DUF1471 domain-containing protein | - |
| C6W65_RS26655 () | 104504..104845 | + | 342 | WP_106907161.1 | Multiple antibiotic resistance protein MarA | VF |
| C6W65_RS26660 () | 104874..106043 | + | 1170 | WP_106907178.1 | Multidrug efflux pump subunit AcrA | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|