MGE detailed information
MGE type: Conjugative plasmid MGE length: 133438 bp
Accession: NZ_CP027311 Location: 1..133438 Organism: Escherichia coli strain 2014C-4135 Replicon: plasmid unnamed
Accession: NZ_CP027311 Location: 1..133438 Organism: Escherichia coli strain 2014C-4135 Replicon: plasmid unnamed
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6N22_RS25485 () | 1584..2018 | + | 435 | WP_000845873.1 | conjugation system SOS inhibitor PsiB | - |
| C6N22_RS25490 () | 2015..2734 | + | 720 | WP_044863095.1 | plasmid SOS inhibition protein A | - |
| - () | 2746..2957 | + | 212 | NuclAT_0 | - | Antitoxin Detail |
| - () | 2746..2957 | + | 212 | NuclAT_0 | - | Antitoxin Detail |
| - () | 2746..2957 | + | 212 | NuclAT_0 | - | Antitoxin Detail |
| - () | 2746..2957 | + | 212 | NuclAT_0 | - | Antitoxin Detail |
| C6N22_RS25495 () | 3010..3171 | + | 162 | WP_001332444.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| C6N22_RS26630 () | 3472..3750 | - | 279 | Protein_4 | hypothetical protein | - |
| C6N22_RS25515 () | 4157..4354 | + | 198 | WP_170923508.1 | hypothetical protein | - |
| C6N22_RS25520 () | 4473..5294 | + | 822 | WP_044862944.1 | DUF945 domain-containing protein | - |
| C6N22_RS25525 () | 5590..6180 | - | 591 | WP_199852244.1 | hypothetical protein | VF |
| C6N22_RS25530 () | 6514..6897 | + | 384 | WP_044862945.1 | relaxosome protein TraM | - |
| C6N22_RS25535 () | 7084..7773 | + | 690 | WP_044862946.1 | conjugal transfer transcriptional regulator TraJ | - |
| C6N22_RS25540 () | 7872..8267 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| C6N22_RS25545 () | 8300..8665 | + | 366 | WP_000994782.1 | type IV conjugative transfer system pilin TraA | - |
| C6N22_RS25550 () | 8680..8991 | + | 312 | WP_000012126.1 | type IV conjugative transfer system protein TraL | - |
| C6N22_RS25555 () | 9013..9579 | + | 567 | WP_044862947.1 | type IV conjugative transfer system protein TraE | - |
| C6N22_RS25560 () | 9590..10294 | + | 705 | WP_148936010.1 | type-F conjugative transfer system secretin TraK | - |
| C6N22_RS25565 () | 10294..11721 | + | 1428 | WP_050866955.1 | conjugal transfer protein TraB | - |
| C6N22_RS25570 () | 11711..12301 | + | 591 | WP_050866956.1 | conjugal transfer protein TraP | - |
| C6N22_RS25575 () | 12255..12485 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| C6N22_RS25580 () | 12497..12748 | + | 252 | WP_044862950.1 | conjugal transfer protein TrbG | - |
| C6N22_RS25585 () | 12745..13260 | + | 516 | WP_044862951.1 | type IV conjugative transfer system lipoprotein TraV | - |
| C6N22_RS25590 () | 13395..13616 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| C6N22_RS25595 () | 13776..16403 | + | 2628 | WP_044862953.1 | type IV secretion system protein TraC | - |
| C6N22_RS25600 () | 16400..16786 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| C6N22_RS25605 () | 16783..17415 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| C6N22_RS25610 () | 17412..18404 | + | 993 | WP_024226181.1 | conjugal transfer pilus assembly protein TraU | - |
| C6N22_RS25615 () | 18413..19051 | + | 639 | WP_044862954.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| C6N22_RS25620 () | 19048..20855 | + | 1808 | Protein_26 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| C6N22_RS25625 () | 20882..21139 | + | 258 | WP_044862956.1 | conjugal transfer protein TrbE | - |
| C6N22_RS25630 () | 21132..21874 | + | 743 | Protein_28 | type-F conjugative transfer system pilin assembly protein TraF | - |
| C6N22_RS25635 () | 21890..22237 | + | 348 | WP_044862957.1 | conjugal transfer protein TrbA | - |
| C6N22_RS25640 () | 22356..22640 | + | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C6N22_RS25645 () | 22627..23181 | + | 555 | WP_044862958.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C6N22_RS25650 () | 23111..23453 | + | 343 | Protein_32 | P-type conjugative transfer protein TrbJ | - |
| C6N22_RS25655 () | 23407..23832 | + | 426 | WP_072044805.1 | F-type conjugal transfer protein TrbF | - |
| C6N22_RS25660 () | 23819..25192 | + | 1374 | WP_044862960.1 | conjugal transfer protein TraH | - |
| C6N22_RS25665 () | 25189..28002 | + | 2814 | WP_050866957.1 | conjugal transfer mating pair stabilization protein TraG | - |
| C6N22_RS25670 () | 28027..28524 | + | 498 | WP_038341570.1 | surface exclusion protein | - |
| C6N22_RS25675 () | 28556..29287 | + | 732 | WP_158707433.1 | complement resistance protein TraT | - |
| C6N22_RS25680 () | 29491..29970 | + | 480 | WP_106904134.1 | hypothetical protein | - |
| C6N22_RS25685 () | 30252..32540 | + | 2289 | WP_106904131.1 | Coupling protein TraD | VF |
| C6N22_RS25690 () | 32540..37809 | + | 5270 | Protein_40 | Multifunctional conjugation protein TraI | Relaxase |
| C6N22_RS25695 () | 37829..38575 | + | 747 | WP_000205707.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| C6N22_RS25700 () | 38657..39025 | + | 369 | WP_000722534.1 | NirD/YgiW/YdeI family stress tolerance protein | - |
| C6N22_RS25705 () | 39061..39618 | + | 558 | WP_044863028.1 | fertility inhibition protein FinO | - |
| C6N22_RS25715 () | 40718..41179 | + | 462 | WP_044863027.1 | thermonuclease family protein | - |
| C6N22_RS25720 () | 41282..41665 | + | 384 | WP_001109064.1 | hypothetical protein | - |
| - () | 41840..41901 | - | 62 | NuclAT_1 | - | - |
| - () | 41840..41901 | - | 62 | NuclAT_1 | - | - |
| - () | 41840..41901 | - | 62 | NuclAT_1 | - | - |
| - () | 41840..41901 | - | 62 | NuclAT_1 | - | - |
| C6N22_RS25730 () | 41888..42094 | + | 207 | WP_032186826.1 | type I toxin-antitoxin system Hok family toxin | - |
| C6N22_RS25735 () | 42378..42635 | + | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| C6N22_RS25740 () | 42871..42945 | + | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| C6N22_RS25745 () | 42938..43795 | + | 858 | WP_044863026.1 | incFII family plasmid replication initiator RepA | - |
| C6N22_RS26635 () | 44534..44758 | + | 225 | WP_072097550.1 | hypothetical protein | - |
| C6N22_RS25765 () | 44771..45010 | + | 240 | WP_000859017.1 | MarR family transcriptional regulator | - |
| C6N22_RS25775 () | 45624..47390 | + | 1767 | WP_044863025.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| C6N22_RS25780 () | 47403..51945 | + | 4543 | Protein_53 | tRNA nuclease CdiA | VF |
| C6N22_RS25785 () | 51977..53590 | - | 1614 | WP_044863092.1 | IS66 family transposase ISEc23 | Transposase |
| C6N22_RS25790 () | 53621..53971 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| C6N22_RS25795 () | 53968..54393 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| C6N22_RS25800 () | 54480..59540 | + | 5061 | Protein_57 | tRNA nuclease CdiA | VF |
| C6N22_RS25815 () | 60030..60707 | - | 678 | WP_044808430.1 | hypothetical protein | - |
| C6N22_RS25820 () | 60866..61252 | + | 387 | WP_044808429.1 | thermonuclease family protein | - |
| C6N22_RS25825 () | 61749..65648 | + | 3900 | WP_050866954.1 | Serine protease EspP | VF |
| C6N22_RS25835 () | 66154..66519 | + | 366 | WP_044527404.1 | hypothetical protein | - |
| C6N22_RS25840 () | 66529..66720 | + | 192 | WP_024219659.1 | hypothetical protein | - |
| C6N22_RS25845 () | 66751..67062 | + | 312 | WP_029365223.1 | hypothetical protein | - |
| C6N22_RS25850 () | 67181..67645 | + | 465 | WP_077786731.1 | IS3 family transposase ISEcB1 | Transposase |
| C6N22_RS25860 () | 68002..68700 | - | 699 | WP_044808426.1 | lactate utilization protein C | - |
| C6N22_RS25865 () | 68705..70120 | - | 1416 | WP_000054157.1 | iron-sulfur cluster-binding protein | - |
| C6N22_RS25870 () | 70131..70850 | - | 720 | WP_001102132.1 | (Fe-S)-binding protein | - |
| C6N22_RS25875 () | 70900..72456 | - | 1557 | WP_044808425.1 | L-lactate permease | - |
| C6N22_RS25880 () | 72911..73075 | - | 165 | Protein_69 | IS1 family transposase IS1N | Transposase |
| C6N22_RS25885 () | 73105..73355 | - | 251 | Protein_70 | transposase | - |
| C6N22_RS25890 () | 73365..73670 | - | 306 | Protein_71 | IS3 family transposase ISLad1 | Transposase |
| C6N22_RS25895 () | 73687..74072 | - | 386 | Protein_72 | transposase | - |
| C6N22_RS25900 () | 74211..74708 | - | 498 | Protein_73 | IS21 family transposase IS100 | Transposase |
| C6N22_RS25905 () | 74705..75705 | - | 1001 | Protein_74 | IS21 family transposase IS100kyp | Transposase |
| C6N22_RS25910 () | 75812..76137 | - | 326 | Protein_75 | IS3 family transposase ISEal1 | Transposase |
| C6N22_RS25915 () | 76682..76984 | + | 303 | WP_071827458.1 | Major pilu subunit operon regulatory protein PapB | VF |
| C6N22_RS25920 () | 77042..78310 | + | 1269 | WP_033817121.1 | TolC family protein | - |
| C6N22_RS25925 () | 78307..80454 | + | 2148 | WP_001620877.1 | Toxin RTX-I translocation ATP-binding protein | VF |
| C6N22_RS25930 () | 80514..81761 | + | 1248 | WP_001620879.1 | HlyD family type I secretion periplasmic adaptor subunit | - |
| C6N22_RS25935 () | 81979..93552 | + | 11574 | WP_106904132.1 | hypothetical protein | - |
| C6N22_RS25940 () | 93631..95499 | + | 1869 | WP_033817154.1 | Lipase | VF |
| C6N22_RS25945 () | 95751..96320 | + | 570 | WP_028985823.1 | hypothetical protein | - |
| C6N22_RS25950 () | 96479..97270 | - | 792 | WP_001774400.1 | DUF4198 domain-containing protein | - |
| C6N22_RS25955 () | 97289..99259 | - | 1971 | WP_028985821.1 | Hemin receptor | VF |
| C6N22_RS25965 () | 100721..100993 | + | 273 | WP_071827457.1 | Major pilu subunit operon regulatory protein PapB | VF |
| C6N22_RS25970 () | 101328..101986 | + | 659 | Protein_86 | transposase | - |
| C6N22_RS25975 () | 102006..102289 | + | 284 | Protein_87 | IS3 family transposase | - |
| C6N22_RS25980 () | 102568..103737 | - | 1170 | WP_044863044.1 | hypothetical protein | - |
| C6N22_RS25990 () | 104395..105135 | + | 741 | WP_044863041.1 | tyrosine-type recombinase/integrase | - |
| C6N22_RS25995 () | 105378..106355 | - | 978 | WP_044808417.1 | RepB family plasmid replication initiator protein | - |
| C6N22_RS26005 () | 107261..108530 | + | 1270 | Protein_91 | colicin-Ia | - |
| C6N22_RS26010 () | 108552..108887 | - | 336 | WP_001080730.1 | colicin 1A immunity protein | - |
| C6N22_RS26020 () | 109016..109363 | + | 348 | WP_000142441.1 | hypothetical protein | - |
| C6N22_RS26025 () | 109381..109971 | - | 591 | WP_000194574.1 | hypothetical protein | - |
| C6N22_RS26030 () | 109971..110228 | - | 258 | WP_000343085.1 | hypothetical protein | - |
| C6N22_RS26035 () | 110557..111009 | + | 453 | WP_000670961.1 | dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase | VF |
| C6N22_RS26040 () | 111042..112574 | - | 1533 | WP_032308905.1 | NAD(P)-binding domain-containing protein | - |
| C6N22_RS26045 () | 112571..112840 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| C6N22_RS26050 () | 112842..113858 | - | 1017 | WP_000583427.1 | Gfo/Idh/MocA family oxidoreductase | - |
| C6N22_RS26055 () | 113858..114688 | - | 831 | WP_016230897.1 | HAD-IIB family hydrolase | - |
| C6N22_RS26060 () | 114672..115910 | - | 1239 | WP_024178320.1 | 3-oxo-glucose-6-phosphate:glutamate aminotransferase | VF |
| C6N22_RS26065 () | 116503..117549 | + | 1047 | WP_024232765.1 | SIR2 family protein | - |
| C6N22_RS26070 () | 117546..119354 | + | 1809 | WP_044863035.1 | ATP-binding protein | - |
| C6N22_RS26075 () | 120019..120237 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| C6N22_RS26080 () | 120239..120544 | + | 306 | WP_050866971.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| C6N22_RS26085 () | 120545..121354 | + | 810 | WP_000016979.1 | site-specific integrase | - |
| C6N22_RS26090 () | 121492..121767 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| C6N22_RS26095 () | 121761..122405 | - | 645 | WP_000633911.1 | AAA family ATPase | - |
| C6N22_RS26100 () | 122634..123605 | + | 972 | WP_001103694.1 | hypothetical protein | - |
| C6N22_RS26105 () | 123610..124002 | + | 393 | WP_000340833.1 | plasmid partitioning/stability family protein | - |
| C6N22_RS26115 () | 124007..125272 | - | 1266 | Protein_111 | translesion error-prone DNA polymerase V subunit UmuC | - |
| C6N22_RS26120 () | 125272..125709 | - | 438 | WP_032219119.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| C6N22_RS26125 () | 125706..125954 | - | 249 | WP_019842136.1 | DinI-like family protein | - |
| C6N22_RS26135 () | 126372..127274 | + | 903 | WP_135279999.1 | DUF1281 domain-containing protein | - |
| C6N22_RS26140 () | 127271..127582 | + | 312 | WP_032219116.1 | hypothetical protein | - |
| C6N22_RS26145 () | 127659..128342 | + | 684 | WP_050866973.1 | DNA methylase | - |
| C6N22_RS26150 () | 128343..128564 | + | 222 | WP_001104885.1 | hypothetical protein | - |
| C6N22_RS26155 () | 128578..129012 | + | 435 | WP_040072501.1 | DUF1380 family protein | - |
| C6N22_RS26490 () | 129057..129827 | + | 771 | WP_044863077.1 | hypothetical protein | - |
| C6N22_RS26170 () | 130367..130669 | + | 303 | WP_001436678.1 | antirestriction protein | - |
| C6N22_RS26175 () | 130716..131135 | + | 420 | WP_000271711.1 | DUF1380 family protein | - |
| C6N22_RS26180 () | 131135..131326 | + | 192 | WP_001027497.1 | hypothetical protein | - |
| C6N22_RS26200 () | 132111..132650 | + | 540 | WP_044863124.1 | single-stranded DNA-binding protein | - |
| C6N22_RS26205 () | 132713..132946 | + | 234 | WP_000005988.1 | DUF905 family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|