MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 97481 bp
Accession: NZ_CP026591 Location: 2053693..2151173 Organism: Clostridioides difficile strain CD-17-01474 Replicon: chromosome
Accession: NZ_CP026591 Location: 2053693..2151173 Organism: Clostridioides difficile strain CD-17-01474 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C3L34_RS09905 () | 2049183..2050433 | + | 1251 | Protein_1811 | DUF11 domain-containing protein | - |
| C3L34_RS09910 () | 2050743..2051024 | + | 282 | WP_009891898.1 | hypothetical protein | - |
| C3L34_RS09915 () | 2051110..2052132 | + | 1023 | WP_009891897.1 | hypothetical protein | - |
| C3L34_RS09920 () | 2052134..2052619 | + | 486 | WP_009891896.1 | PcfB family protein | - |
| C3L34_RS09925 () | 2052616..2053620 | + | 1005 | WP_104732836.1 | type IV secretory system conjugative DNA transfer family protein | - |
| C3L34_RS09930 () | 2053693..2055573 | + | 1881 | WP_012816185.1 | hypothetical protein ; Integrase | Integrase |
| C3L34_RS09935 () | 2055600..2055953 | + | 354 | WP_012816186.1 | TnpV protein | - |
| C3L34_RS09940 () | 2055970..2056269 | + | 300 | WP_004612693.1 | hypothetical protein | - |
| C3L34_RS09945 () | 2056297..2056665 | - | 369 | WP_012816188.1 | helix-turn-helix transcriptional regulator | - |
| C3L34_RS09950 () | 2056810..2056998 | + | 189 | WP_007884040.1 | helix-turn-helix domain-containing protein | - |
| C3L34_RS09955 () | 2056991..2057683 | + | 693 | WP_024738629.1 | Transcriptional regulatory protein WalR | VF |
| C3L34_RS09960 () | 2057689..2058606 | + | 918 | WP_012816190.1 | HAMP domain-containing histidine kinase | - |
| C3L34_RS09965 () | 2058741..2059667 | + | 927 | WP_104732837.1 | Daunorubicin/doxorubicin resistance ATP-binding protein DrrA | VF |
| C3L34_RS09970 () | 2059660..2060445 | + | 786 | WP_012816192.1 | ABC transporter permease | - |
| C3L34_RS09975 () | 2060448..2061227 | + | 780 | WP_002594767.1 | ABC transporter permease | - |
| C3L34_RS09980 () | 2061235..2061696 | + | 462 | WP_012816193.1 | hypothetical protein | - |
| C3L34_RS09990 () | 2062141..2062554 | + | 414 | WP_012816194.1 | hypothetical protein | - |
| C3L34_RS09995 () | 2062656..2063108 | + | 453 | WP_012816195.1 | sigma-24 (feci) | - |
| C3L34_RS10000 () | 2063119..2063580 | + | 462 | WP_009296689.1 | sigma-70 family RNA polymerase sigma factor | - |
| C3L34_RS10005 () | 2063609..2063899 | + | 291 | WP_024739841.1 | DUF3847 domain-containing protein | - |
| C3L34_RS10010 () | 2064086..2065531 | + | 1446 | WP_104732839.1 | MobA/MobL family protein | - |
| C3L34_RS10015 () | 2065639..2065929 | - | 291 | WP_002596328.1 | type II toxin-antitoxin system YafQ family toxin | Toxin Detail |
| C3L34_RS10020 () | 2065926..2066204 | - | 279 | WP_005924829.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin Detail |
| C3L34_RS10025 () | 2066331..2066729 | + | 399 | WP_012816198.1 | cysteine-rich VLP domain-containing protein | - |
| C3L34_RS10030 () | 2066843..2067577 | + | 735 | WP_012816199.1 | phage replisome organizer N-terminal domain-containing protein | - |
| C3L34_RS10035 () | 2067574..2068437 | + | 864 | WP_104732840.1 | IS21 family transposase ISBlo1 | Transposase |
| C3L34_RS10040 () | 2068481..2068675 | + | 195 | WP_104732841.1 | transposon-encoded TnpW family protein | - |
| C3L34_RS10045 () | 2068753..2069118 | + | 366 | WP_104732842.1 | hypothetical protein | - |
| C3L34_RS10050 () | 2069213..2069839 | + | 627 | Protein_1839 | TraM recognition domain-containing protein | - |
| C3L34_RS10055 () | 2069892..2070269 | + | 378 | WP_009891894.1 | TnpV protein | - |
| C3L34_RS10060 () | 2070283..2070564 | + | 282 | WP_009891893.1 | hypothetical protein | - |
| C3L34_RS10065 () | 2070686..2071534 | - | 849 | WP_009891891.1 | helix-turn-helix domain-containing protein | - |
| C3L34_RS10070 () | 2071900..2072193 | + | 294 | WP_021407349.1 | hypothetical protein | - |
| C3L34_RS10075 () | 2072177..2072482 | + | 306 | WP_074014306.1 | molecular chaperone | - |
| C3L34_RS10080 () | 2072910..2074154 | + | 1245 | WP_021422885.1 | hypothetical protein | - |
| C3L34_RS10085 () | 2074170..2074856 | + | 687 | WP_074014307.1 | DNA primase | - |
| C3L34_RS10090 () | 2074816..2076174 | + | 1359 | WP_009891879.1 | virulence-associated E family protein | - |
| C3L34_RS19815 () | 2076442..2076609 | + | 168 | WP_009891878.1 | hypothetical protein | - |
| C3L34_RS10095 () | 2076682..2078334 | + | 1653 | WP_012816204.1 | hypothetical protein ; Integrase | Integrase |
| C3L34_RS10100 () | 2078382..2078837 | - | 456 | WP_009901261.1 | hypothetical protein | - |
| C3L34_RS10105 () | 2078861..2080534 | - | 1674 | WP_009893984.1 | hypothetical protein ; Integrase | Integrase |
| C3L34_RS10110 () | 2080612..2080785 | - | 174 | WP_002604472.1 | transposon-encoded TnpW family protein | - |
| C3L34_RS10120 () | 2081244..2081486 | - | 243 | WP_002604473.1 | helix-turn-helix domain-containing protein | - |
| C3L34_RS10125 () | 2081470..2081907 | - | 438 | WP_002604474.1 | sigma-70 family RNA polymerase sigma factor | - |
| C3L34_RS10130 () | 2082381..2083364 | - | 984 | WP_002584956.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| C3L34_RS10135 () | 2083381..2083566 | - | 186 | WP_003431289.1 | hypothetical protein | - |
| C3L34_RS10140 () | 2084177..2084338 | + | 162 | Protein_1857 | helix-turn-helix transcriptional regulator | - |
| C3L34_RS10145 () | 2084609..2085319 | - | 711 | WP_009891854.1 | LytTR family DNA-binding domain-containing protein | - |
| C3L34_RS10150 () | 2085324..2085497 | - | 174 | WP_002576203.1 | helix-turn-helix domain-containing protein | - |
| C3L34_RS10155 () | 2085639..2085872 | + | 234 | Protein_1860 | conjugal transfer protein TraG | - |
| C3L34_RS10165 () | 2086036..2086347 | + | 312 | WP_009891846.1 | single-stranded DNA-binding protein | - |
| C3L34_RS10170 () | 2086351..2086509 | + | 159 | WP_042520385.1 | conjugal transfer protein | - |
| C3L34_RS10175 () | 2086665..2086937 | + | 273 | WP_009274451.1 | helix-turn-helix domain-containing protein | - |
| C3L34_RS10180 () | 2086897..2087274 | + | 378 | WP_009274452.1 | TnpV protein | - |
| C3L34_RS10185 () | 2087391..2087825 | + | 435 | WP_009274453.1 | MarR family transcriptional regulator | - |
| C3L34_RS10190 () | 2087818..2089119 | + | 1302 | WP_012816206.1 | multidrug transporter MatE | - |
| C3L34_RS10195 () | 2089213..2090019 | - | 807 | WP_012816207.1 | helix-turn-helix domain-containing protein | - |
| C3L34_RS10205 () | 2090503..2090691 | + | 189 | WP_055058411.1 | hypothetical protein | - |
| C3L34_RS10210 () | 2090688..2091029 | + | 342 | WP_003020305.1 | DeoR family transcriptional regulator | - |
| C3L34_RS10215 () | 2091022..2091318 | + | 297 | WP_012816208.1 | DUF3847 domain-containing protein | - |
| C3L34_RS19820 () | 2091618..2091761 | + | 144 | WP_009274458.1 | hypothetical protein | - |
| C3L34_RS10225 () | 2091949..2093529 | + | 1581 | WP_042520383.1 | MobA/MobL family protein | - |
| C3L34_RS10230 () | 2093595..2094239 | + | 645 | WP_042520382.1 | hypothetical protein | - |
| C3L34_RS10235 () | 2094208..2095545 | + | 1338 | WP_042520381.1 | virulence-associated E family protein | - |
| C3L34_RS10245 () | 2095787..2095984 | + | 198 | WP_004612761.1 | hypothetical protein | - |
| C3L34_RS10250 () | 2095985..2097655 | + | 1671 | WP_012816213.1 | hypothetical protein ; Integrase | Integrase |
| C3L34_RS10255 () | 2097746..2097829 | + | 84 | Protein_1877 | hypothetical protein | - |
| C3L34_RS10260 () | 2097849..2098712 | + | 864 | WP_009893980.1 | hypothetical protein | - |
| C3L34_RS10265 () | 2098730..2098990 | + | 261 | WP_009888259.1 | hypothetical protein | - |
| C3L34_RS10270 () | 2098994..2099383 | + | 390 | WP_009888260.1 | PrgI family protein | - |
| C3L34_RS10275 () | 2099295..2101724 | + | 2430 | WP_009888261.1 | ATP-binding protein | - |
| C3L34_RS10280 () | 2101728..2103860 | + | 2133 | WP_009888262.1 | CHAP domain-containing protein | - |
| C3L34_RS10285 () | 2103872..2104111 | + | 240 | WP_009888263.1 | hypothetical protein | - |
| C3L34_RS10290 () | 2104086..2105627 | + | 1542 | WP_009893977.1 | DUF4366 domain-containing protein | - |
| C3L34_RS10295 () | 2105722..2107428 | + | 1707 | WP_009893975.1 | DNA topoisomerase 3 | - |
| C3L34_RS10300 () | 2107513..2108316 | + | 804 | WP_004804477.1 | KilA-N domain-containing protein | - |
| C3L34_RS10305 () | 2108399..2117128 | + | 8730 | WP_009893973.1 | DEAD/DEAH box helicase family protein | - |
| C3L34_RS10310 () | 2117171..2117830 | + | 660 | WP_010826392.1 | hypothetical protein | - |
| C3L34_RS10315 () | 2117970..2118200 | + | 231 | WP_009889816.1 | helix-turn-helix transcriptional regulator | - |
| C3L34_RS10320 () | 2118403..2120025 | + | 1623 | WP_009889819.1 | AAA family ATPase | - |
| C3L34_RS10325 () | 2120022..2121089 | + | 1068 | WP_009889821.1 | UvrD-helicase domain-containing protein | - |
| C3L34_RS10330 () | 2121117..2121578 | + | 462 | WP_009889823.1 | hypothetical protein | - |
| C3L34_RS10335 () | 2121568..2122374 | + | 807 | WP_009889825.1 | PQQ-like beta-propeller repeat protein | - |
| C3L34_RS10340 () | 2122410..2123741 | - | 1332 | WP_009889829.1 | relaxase/mobilization nuclease domain-containing protein | - |
| C3L34_RS10345 () | 2123747..2124097 | - | 351 | WP_009889831.1 | plasmid mobilization relaxosome protein MobC | - |
| C3L34_RS10350 () | 2124431..2125588 | + | 1158 | WP_009893966.1 | TlpA family protein disulfide reductase | - |
| C3L34_RS19825 () | 2125667..2125762 | + | 96 | WP_196783929.1 | thioredoxin | - |
| C3L34_RS10360 () | 2125755..2126645 | + | 891 | WP_009889834.1 | 4Fe-4S binding protein | - |
| C3L34_RS10365 () | 2126664..2127941 | + | 1278 | WP_009889836.1 | ABC transporter permease | - |
| C3L34_RS10370 () | 2127951..2128607 | + | 657 | WP_003426165.1 | putative ABC transporter ATP-binding protein | VF |
| C3L34_RS10375 () | 2128607..2129983 | + | 1377 | WP_009893965.1 | ABC transporter permease | - |
| C3L34_RS10380 () | 2130081..2130734 | + | 654 | WP_009889840.1 | Transcriptional regulatory protein QseB | VF |
| C3L34_RS10385 () | 2130731..2132050 | + | 1320 | WP_009889841.1 | HAMP domain-containing histidine kinase | - |
| C3L34_RS10395 () | 2132574..2132984 | + | 411 | WP_003426191.1 | sigma-70 family RNA polymerase sigma factor | - |
| C3L34_RS10400 () | 2133473..2133625 | + | 153 | WP_003426199.1 | hypothetical protein | - |
| C3L34_RS19830 () | 2133726..2135375 | + | 1650 | Protein_1906 | Tn3 family transposase TnpR_ISAcsp1 | Transposase |
| C3L34_RS10405 () | 2135400..2138648 | + | 3249 | Protein_1907 | Tn3 family transposase TnpR_ISAcsp1 | Transposase |
| C3L34_RS10410 () | 2139105..2139452 | + | 348 | WP_003435528.1 | cupin domain-containing protein | - |
| C3L34_RS10415 () | 2139602..2140651 | - | 1050 | WP_003423932.1 | ABC transporter substrate-binding protein | - |
| C3L34_RS10420 () | 2141037..2141771 | + | 735 | WP_009889846.1 | class I SAM-dependent methyltransferase | - |
| C3L34_RS10425 () | 2141913..2142404 | - | 492 | WP_003428667.1 | prolyl-tRNA synthetase associated domain-containing protein | - |
| C3L34_RS10430 () | 2142753..2143136 | + | 384 | WP_009889847.1 | hypothetical protein | - |
| C3L34_RS10435 () | 2143642..2144025 | + | 384 | WP_003428669.1 | YtxH domain-containing protein | - |
| C3L34_RS10440 () | 2144027..2144377 | + | 351 | WP_003428670.1 | hypothetical protein | - |
| C3L34_RS10445 () | 2144471..2144929 | - | 459 | WP_003435468.1 | hypothetical protein | - |
| C3L34_RS10450 () | 2144974..2145762 | - | 789 | WP_003435466.1 | N-acetylmuramoyl-L-alanine amidase | - |
| C3L34_RS10455 () | 2145901..2146338 | - | 438 | WP_009889849.1 | dCMP deaminase | - |
| C3L34_RS10465 () | 2147160..2147669 | + | 510 | WP_009889853.1 | HTH-type transcriptional regulator ImmR | VF |
| C3L34_RS10480 () | 2148580..2149380 | - | 801 | WP_003435446.1 | ABC transporter permease | - |
| C3L34_RS10490 () | 2149575..2151173 | - | 1599 | WP_009893325.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| C3L34_RS10495 () | 2151501..2151677 | + | 177 | WP_009889863.1 | hypothetical protein | - |
| C3L34_RS10500 () | 2151851..2152981 | + | 1131 | WP_009893327.1 | iron-containing alcohol dehydrogenase | - |
| C3L34_RS10505 () | 2153222..2153572 | + | 351 | WP_009893329.1 | BMC domain-containing protein | - |
| C3L34_RS10510 () | 2153580..2154029 | + | 450 | WP_009889866.1 | EutP/PduV family microcompartment system protein | - |
| C3L34_RS10515 () | 2154131..2154706 | + | 576 | WP_003423977.1 | response regulator | - |
| C3L34_RS10520 () | 2154699..2156108 | + | 1410 | WP_009889869.1 | histidine kinase N-terminal domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|---|---|---|---|---|---|
| Clostridium difficile R20291 | Integrative and Conjugative Element | TA10095 | NC_013316 | 2043677..2141157 | 0 |