MGE detailed information
MGE type: Conjugative plasmid MGE length: 144225 bp
Accession: NZ_CP025626 Location: 1..144225 Organism: Escherichia coli strain SCEC020007 Replicon: plasmid pNDM5_020007
Accession: NZ_CP025626 Location: 1..144225 Organism: Escherichia coli strain SCEC020007 Replicon: plasmid pNDM5_020007
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C0634_RS26005 () | 1..858 | + | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| C0634_RS00590 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| C0634_RS26010 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| C0634_RS00595 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| C0634_RS00605 () | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| C0634_RS00610 () | 6263..6868 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| C0634_RS00615 () | 6892..7641 | - | 750 | Protein_7 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| C0634_RS00620 () | 7630..8037 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| C0634_RS00625 () | 8175..9059 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| C0634_RS00630 () | 9091..10290 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| C0634_RS00635 () | 10396..11046 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| C0634_RS00640 () | 11078..11320 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| C0634_RS00645 () | 11362..12876 | - | 1515 | Protein_13 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| C0634_RS00650 () | 12942..13646 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C0634_RS00655 () | 13701..14567 | - | 867 | Protein_15 | IS91 family transposase ISAzo26 | Transposase |
| C0634_RS00660 () | 14725..15198 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| C0634_RS00665 () | 15329..16117 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| C0634_RS00670 () | 16323..16670 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| C0634_RS00675 () | 16664..17503 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| C0634_RS00680 () | 17908..19449 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| C0634_RS00690 () | 19762..20793 | + | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| C0634_RS00695 () | 20804..21442 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| C0634_RS00700 () | 21447..21812 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| C0634_RS00705 () | 21816..22628 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| C0634_RS00710 () | 22729..23022 | - | 294 | Protein_25 | IS30 family transposase ISAba125 | Transposase |
| C0634_RS00715 () | 23187..23891 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C0634_RS00720 () | 23943..24536 | - | 594 | Protein_27 | LacI family DNA-binding transcriptional regulator | - |
| C0634_RS00725 () | 24694..25452 | - | 759 | Protein_28 | site-specific integrase | - |
| C0634_RS00735 () | 25543..26771 | + | 1229 | WP_152924612.1 | IS3 family transposase IS2 | Transposase |
| C0634_RS00740 () | 26756..27325 | + | 570 | WP_089634947.1 | hypothetical protein | - |
| C0634_RS00755 () | 28987..30654 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| C0634_RS00760 () | 30967..31158 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| C0634_RS00765 () | 31155..31577 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| C0634_RS00770 () | 31624..31926 | - | 303 | WP_001666994.1 | antirestriction protein | - |
| C0634_RS00780 () | 32463..33233 | - | 771 | WP_001006251.1 | hypothetical protein | - |
| C0634_RS00785 () | 33278..33712 | - | 435 | WP_001546462.1 | DUF1380 family protein | - |
| C0634_RS00790 () | 33726..33947 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| C0634_RS00795 () | 33948..34631 | - | 684 | WP_032181561.1 | DNA methylase | - |
| C0634_RS00800 () | 34708..35012 | - | 305 | Protein_39 | hypothetical protein | - |
| C0634_RS00805 () | 35016..35918 | - | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| C0634_RS00815 () | 36656..37627 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| C0634_RS00820 () | 37627..38793 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| C0634_RS00825 () | 39381..40136 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| C0634_RS00830 () | 40858..41664 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| C0634_RS00835 () | 41665..41970 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| C0634_RS00840 () | 41972..42190 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| C0634_RS00850 () | 42750..42980 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| C0634_RS00855 () | 42977..43393 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| C0634_RS00860 () | 43468..45033 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| C0634_RS00865 () | 45018..46040 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| C0634_RS00875 () | 46294..46991 | - | 698 | Protein_51 | IS1 family transposase IS1A | Transposase |
| C0634_RS00885 () | 47141..47838 | - | 698 | Protein_52 | IS1 family transposase IS1X2 | Transposase |
| C0634_RS26630 () | 48038..48151 | + | 114 | Protein_53 | IS6 family transposase | - |
| C0634_RS00905 () | 48301..48459 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| C0634_RS00910 () | 48449..48955 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| C0634_RS00915 () | 49138..49953 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| C0634_RS00925 () | 50300..52186 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| C0634_RS00930 () | 52227..52754 | + | 528 | WP_000178050.1 | iron transporter | - |
| C0634_RS00935 () | 52858..54237 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| C0634_RS00940 () | 54240..55523 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| C0634_RS00945 () | 55513..56643 | + | 1131 | WP_000729219.1 | ABC transporter permease | - |
| C0634_RS00950 () | 56648..57343 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| C0634_RS00955 () | 57330..57815 | + | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| C0634_RS00960 () | 57840..58325 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| C0634_RS00965 () | 58447..59079 | + | 633 | Protein_65 | histidine-type phosphatase | - |
| C0634_RS00970 () | 59229..59333 | - | 105 | Protein_66 | IS5/IS1182 family transposase | - |
| C0634_RS00975 () | 59367..61781 | - | 2415 | Protein_67 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| C0634_RS00980 () | 61839..62543 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| C0634_RS26410 () | 62596..62844 | - | 249 | Protein_69 | DUF3330 domain-containing protein | - |
| C0634_RS00995 () | 63047..64060 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| C0634_RS01000 () | 64205..64702 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| C0634_RS26030 () | 64814..65104 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| C0634_RS01005 () | 65110..65901 | + | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| C0634_RS01010 () | 66065..66412 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| C0634_RS01015 () | 66406..67245 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| C0634_RS01025 () | 67373..67576 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| C0634_RS01030 () | 67732..68937 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| C0634_RS01035 () | 68948..69253 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| C0634_RS26415 () | 69297..69362 | + | 66 | Protein_79 | EAL domain-containing protein | - |
| C0634_RS01045 () | 69480..70244 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| C0634_RS01060 () | 70737..71321 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| C0634_RS01065 () | 71321..72559 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| C0634_RS01070 () | 72556..73461 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| C0634_RS01080 () | 73583..74287 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C0634_RS01085 () | 74452..74745 | + | 294 | Protein_85 | IS30 family transposase ISAba125 | Transposase |
| C0634_RS01090 () | 74846..75658 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| C0634_RS01095 () | 75662..76027 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| C0634_RS01100 () | 76032..76670 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| C0634_RS01105 () | 76681..77712 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| C0634_RS01115 () | 78025..79566 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| C0634_RS01120 () | 79971..80810 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| C0634_RS01125 () | 80804..81151 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| C0634_RS01130 () | 81357..82145 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| C0634_RS01135 () | 82276..82749 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| C0634_RS01140 () | 82907..83773 | + | 867 | Protein_95 | IS91 family transposase ISAzo26 | Transposase |
| C0634_RS01145 () | 83828..84532 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C0634_RS01150 () | 84597..87050 | - | 2454 | Protein_97 | Tn3 family transposase TnpA_Tn3 | Transposase |
| C0634_RS01155 () | 87214..87771 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| C0634_RS01160 () | 87954..88814 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| C0634_RS01165 () | 88984..89739 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| C0634_RS01170 () | 89820..90368 | - | 549 | WP_014342204.1 | cation:proton antiporter | - |
| C0634_RS01175 () | 90431..90781 | + | 351 | Protein_102 | 60 kDa chaperonin | VF |
| C0634_RS01180 () | 90975..91679 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C0634_RS01190 () | 91744..92952 | + | 1209 | Protein_104 | alpha-galactosidase | - |
| C0634_RS01195 () | 93015..94292 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| C0634_RS01200 () | 94289..95722 | + | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| C0634_RS01205 () | 95917..97311 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
| C0634_RS01215 () | 97557..97661 | - | 105 | Protein_108 | thiosulfate reductase cytochrome B subunit | - |
| C0634_RS01225 () | 97718..98415 | + | 698 | Protein_109 | IS1 family transposase IS1A | Transposase |
| C0634_RS01230 () | 98431..99054 | + | 624 | WP_000912556.1 | potassium channel family protein | - |
| C0634_RS01235 () | 99139..99390 | + | 252 | Protein_111 | iron-containing alcohol dehydrogenase | - |
| C0634_RS01240 () | 99679..99996 | - | 318 | Protein_112 | IS110 family transposase IS1618 | Transposase |
| C0634_RS01245 () | 100151..100256 | + | 106 | Protein_113 | plasmid SOS inhibition protein A | - |
| - () | 100225..100415 | + | 191 | NuclAT_0 | - | - |
| - () | 100225..100415 | + | 191 | NuclAT_0 | - | - |
| - () | 100225..100415 | + | 191 | NuclAT_0 | - | - |
| - () | 100225..100415 | + | 191 | NuclAT_0 | - | - |
| C0634_RS01255 () | 101934..102092 | + | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | - |
| C0634_RS26420 () | 102760..102966 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| C0634_RS01265 () | 102991..103278 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| C0634_RS01270 () | 103397..104218 | + | 822 | WP_001234465.1 | DUF945 domain-containing protein | - |
| C0634_RS01275 () | 104514..105086 | - | 573 | WP_000949660.1 | hypothetical protein | VF |
| C0634_RS01280 () | 105456..105839 | + | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| C0634_RS01285 () | 106030..106677 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| C0634_RS01290 () | 106813..107028 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| C0634_RS01295 () | 107071..107436 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| C0634_RS01300 () | 107451..107762 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| C0634_RS01305 () | 107784..108350 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| C0634_RS01310 () | 108361..109065 | + | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| C0634_RS01315 () | 109065..110492 | + | 1428 | WP_001553836.1 | conjugal transfer protein TraB | - |
| C0634_RS01320 () | 110482..111072 | + | 591 | WP_087523585.1 | conjugal transfer protein TraP | - |
| C0634_RS26035 () | 111059..111196 | + | 138 | WP_001553834.1 | conjugal transfer protein TrbD | - |
| C0634_RS01325 () | 111218..111379 | + | 162 | WP_000741714.1 | conjugal transfer protein TrbD | - |
| C0634_RS01330 () | 111372..111623 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| C0634_RS01335 () | 111620..112135 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| C0634_RS01340 () | 112270..112491 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| C0634_RS01345 () | 112651..115278 | + | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| C0634_RS01350 () | 115275..115661 | + | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| C0634_RS01355 () | 115658..116290 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| C0634_RS01360 () | 116287..117279 | + | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| C0634_RS01365 () | 117288..117926 | + | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| C0634_RS01370 () | 117923..119731 | + | 1809 | WP_039023153.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| C0634_RS01375 () | 119758..120015 | + | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| C0634_RS01380 () | 120008..120751 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| C0634_RS01385 () | 120767..121114 | + | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| C0634_RS01390 () | 121233..121517 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C0634_RS01395 () | 121504..122049 | + | 546 | WP_016236310.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C0634_RS01400 () | 121979..122341 | + | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| C0634_RS01405 () | 122341..123714 | + | 1374 | WP_039023150.1 | conjugal transfer protein TraH | - |
| C0634_RS01410 () | 123711..126530 | + | 2820 | WP_039023149.1 | conjugal transfer mating pair stabilization protein TraG | - |
| C0634_RS01415 () | 126549..127046 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| C0634_RS01420 () | 127078..127809 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| C0634_RS01425 () | 128062..130296 | + | 2235 | WP_062914766.1 | type IV conjugative transfer system coupling protein TraD | - |
| C0634_RS01430 () | 130305..130703 | - | 399 | WP_039023147.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| C0634_RS01435 () | 130703..130930 | - | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| C0634_RS01440 () | 131012..136282 | + | 5271 | WP_039023145.1 | Multifunctional conjugation protein TraI | Relaxase |
| C0634_RS01450 () | 136558..138099 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| C0634_RS01455 () | 138114..138860 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| C0634_RS01460 () | 138888..139634 | + | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| C0634_RS01465 () | 139689..140249 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| C0634_RS01470 () | 140380..140589 | + | 210 | WP_039023209.1 | hypothetical protein | - |
| C0634_RS01475 () | 141001..141627 | + | 627 | WP_029702149.1 | hypothetical protein | - |
| C0634_RS01480 () | 141779..142348 | + | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| C0634_RS26570 () | 142723..142989 | + | 267 | WP_087757657.1 | hypothetical protein | - |
| - () | 143128..143189 | - | 62 | NuclAT_1 | - | - |
| - () | 143128..143189 | - | 62 | NuclAT_1 | - | - |
| - () | 143128..143189 | - | 62 | NuclAT_1 | - | - |
| - () | 143128..143189 | - | 62 | NuclAT_1 | - | - |
| C0634_RS01495 () | 143176..143382 | + | 207 | WP_032215358.1 | type I toxin-antitoxin system Hok family toxin | - |
| C0634_RS01500 () | 143666..143923 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|