MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 142988 bp
Accession: NZ_CP025427 Location: 1..142988 Organism: Enterococcus faecium strain SC4 Replicon: plasmid p2
Accession: NZ_CP025427 Location: 1..142988 Organism: Enterococcus faecium strain SC4 Replicon: plasmid p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CX663_RS15660 () | 1..488 | + | 488 | Protein_0 | initiator RepB protein | - |
| CX663_RS15665 () | 523..1290 | + | 768 | WP_010729833.1 | replication initiation protein | - |
| CX663_RS15670 () | 1482..1880 | + | 399 | WP_002320781.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| CX663_RS15675 () | 2187..2560 | - | 374 | Protein_3 | hypothetical protein | - |
| CX663_RS15680 () | 2582..2959 | - | 378 | WP_002350538.1 | hypothetical protein | - |
| CX663_RS15685 () | 2949..3344 | - | 396 | WP_002320784.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| CX663_RS15690 () | 3411..3596 | - | 186 | WP_002320785.1 | type II toxin-antitoxin system HicA family toxin | - |
| CX663_RS15695 () | 3678..3932 | - | 255 | WP_002347534.1 | hypothetical protein | - |
| CX663_RS15700 () | 3954..4190 | - | 237 | WP_002347535.1 | hypothetical protein | - |
| CX663_RS15705 () | 4206..4490 | - | 285 | WP_002347536.1 | hypothetical protein | - |
| CX663_RS15710 () | 4593..4775 | - | 183 | WP_002347537.1 | hypothetical protein | - |
| CX663_RS15715 () | 4984..5523 | - | 540 | WP_025192470.1 | hypothetical protein | - |
| CX663_RS15720 () | 5636..5902 | - | 267 | WP_010729835.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CX663_RS15725 () | 5904..6125 | - | 222 | WP_010729836.1 | DUF1778 domain-containing protein | - |
| CX663_RS15735 () | 6351..7169 | + | 819 | WP_002360989.1 | AAA family ATPase | - |
| CX663_RS15740 () | 7173..7469 | + | 297 | WP_002320793.1 | hypothetical protein | - |
| CX663_RS15745 () | 7651..8004 | - | 354 | WP_010729838.1 | hypothetical protein | - |
| CX663_RS15750 () | 8024..9079 | - | 1056 | WP_010729839.1 | ParM/StbA family protein | - |
| CX663_RS15755 () | 9295..9693 | + | 399 | WP_002352899.1 | hypothetical protein | - |
| CX663_RS16815 () | 9696..9869 | + | 174 | WP_002320797.1 | hypothetical protein | - |
| CX663_RS16820 () | 11846..12019 | - | 174 | WP_002320797.1 | hypothetical protein | - |
| CX663_RS15770 () | 12022..12420 | - | 399 | WP_002352899.1 | hypothetical protein | - |
| CX663_RS15775 () | 12636..13691 | + | 1056 | WP_010729839.1 | ParM/StbA family protein | - |
| CX663_RS15780 () | 13711..14064 | + | 354 | WP_010729838.1 | hypothetical protein | - |
| CX663_RS15785 () | 14246..14542 | - | 297 | WP_002320793.1 | hypothetical protein | - |
| CX663_RS15790 () | 14546..15364 | - | 819 | WP_002360989.1 | AAA family ATPase | - |
| CX663_RS15800 () | 15590..15811 | + | 222 | WP_010729836.1 | DUF1778 domain-containing protein | - |
| CX663_RS15805 () | 15813..16079 | + | 267 | WP_010729835.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CX663_RS15810 () | 16192..16731 | + | 540 | WP_025192470.1 | hypothetical protein | - |
| CX663_RS15815 () | 16940..17122 | + | 183 | WP_002347537.1 | hypothetical protein | - |
| CX663_RS15820 () | 17225..17509 | + | 285 | WP_002347536.1 | hypothetical protein | - |
| CX663_RS15825 () | 17525..17761 | + | 237 | WP_002347535.1 | hypothetical protein | - |
| CX663_RS15830 () | 17783..18037 | + | 255 | WP_002347534.1 | hypothetical protein | - |
| CX663_RS15835 () | 18119..18304 | + | 186 | WP_002320785.1 | type II toxin-antitoxin system HicA family toxin | - |
| CX663_RS15840 () | 18371..18766 | + | 396 | WP_002320784.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| CX663_RS15845 () | 18756..19133 | + | 378 | WP_002350538.1 | hypothetical protein | - |
| CX663_RS15850 () | 19155..19529 | + | 375 | WP_002347532.1 | hypothetical protein | - |
| CX663_RS15855 () | 19836..20234 | - | 399 | WP_002320781.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| CX663_RS15860 () | 20426..21193 | - | 768 | WP_010729833.1 | replication initiation protein | - |
| CX663_RS15865 () | 21228..22451 | - | 1224 | WP_044383777.1 | RepB family plasmid replication initiator protein | - |
| CX663_RS15870 () | 23432..24235 | + | 804 | WP_010729683.1 | replication initiation protein | - |
| CX663_RS15875 () | 24820..25275 | + | 456 | WP_002320776.1 | hypothetical protein | - |
| CX663_RS15880 () | 25394..26452 | + | 1059 | WP_010729682.1 | hypothetical protein | - |
| CX663_RS15885 () | 26494..28443 | + | 1950 | WP_010729681.1 | ATP-dependent Clp protease ATP-binding subunit | - |
| CX663_RS15890 () | 28446..32087 | + | 3642 | WP_010729680.1 | DUF3659 domain-containing protein | - |
| CX663_RS15895 () | 32487..32825 | + | 339 | WP_002347431.1 | hypothetical protein | - |
| CX663_RS15905 () | 33176..35332 | + | 2157 | WP_002347429.1 | hypothetical protein | - |
| CX663_RS15910 () | 35344..35577 | + | 234 | WP_002320768.1 | LPXTG cell wall anchor domain-containing protein | - |
| CX663_RS15915 () | 35567..36433 | + | 867 | WP_002320767.1 | hypothetical protein | - |
| CX663_RS15920 () | 36448..38418 | + | 1971 | WP_002320766.1 | hypothetical protein | - |
| CX663_RS15925 () | 38585..38812 | + | 228 | WP_002320765.1 | hypothetical protein | - |
| CX663_RS15930 () | 38809..39303 | + | 495 | WP_010729679.1 | hypothetical protein | - |
| CX663_RS15935 () | 39478..39813 | + | 336 | WP_010729677.1 | hypothetical protein | - |
| CX663_RS15940 () | 39948..41399 | + | 1452 | WP_199559758.1 | IS1182 family transposase ISEfa7 | Transposase |
| CX663_RS15945 () | 41629..43212 | - | 1584 | WP_010729675.1 | hypothetical protein | - |
| CX663_RS15950 () | 43334..43918 | + | 585 | WP_002347505.1 | hypothetical protein | - |
| CX663_RS15955 () | 43929..44174 | + | 246 | WP_002347506.1 | hypothetical protein | - |
| CX663_RS15960 () | 44180..44902 | + | 723 | WP_010729674.1 | hypothetical protein | - |
| CX663_RS15965 () | 45033..45776 | + | 744 | WP_010729673.1 | hypothetical protein | - |
| CX663_RS15970 () | 45782..46147 | + | 366 | WP_010729672.1 | hypothetical protein | - |
| CX663_RS15975 () | 46163..46693 | + | 531 | WP_010729671.1 | hypothetical protein | - |
| CX663_RS15980 () | 46855..47223 | + | 369 | WP_010729669.1 | hypothetical protein | - |
| CX663_RS15985 () | 47414..47674 | + | 261 | WP_010729668.1 | hypothetical protein | - |
| CX663_RS15990 () | 48292..49092 | + | 801 | WP_010729667.1 | hypothetical protein | - |
| CX663_RS15995 () | 49129..49311 | + | 183 | WP_010729666.1 | hypothetical protein | - |
| CX663_RS16000 () | 49501..49788 | + | 288 | WP_010729665.1 | hypothetical protein | - |
| CX663_RS16005 () | 49879..50118 | + | 240 | WP_025481138.1 | hypothetical protein | - |
| CX663_RS16010 () | 50246..50575 | + | 330 | WP_010729841.1 | hypothetical protein | - |
| CX663_RS16015 () | 50628..51459 | + | 832 | Protein_68 | hypothetical protein | - |
| CX663_RS16020 () | 51474..51791 | + | 318 | WP_002347440.1 | hypothetical protein | - |
| CX663_RS16025 () | 51794..52026 | + | 233 | Protein_70 | hypothetical protein | - |
| CX663_RS16030 () | 52141..52617 | - | 477 | WP_010729846.1 | hypothetical protein | - |
| CX663_RS16035 () | 52743..54074 | + | 1332 | WP_025481139.1 | amidase | - |
| CX663_RS16040 () | 54099..54626 | + | 528 | WP_010729848.1 | hypothetical protein | - |
| CX663_RS16045 () | 54613..55176 | + | 564 | WP_010729849.1 | hypothetical protein | - |
| CX663_RS16050 () | 55594..56331 | + | 738 | WP_010729850.1 | hypothetical protein | - |
| CX663_RS16055 () | 56348..56764 | - | 417 | WP_010729851.1 | hypothetical protein | - |
| CX663_RS16060 () | 57157..58404 | + | 1248 | WP_025481140.1 | C39 family peptidase | - |
| CX663_RS16065 () | 58674..61064 | + | 2391 | WP_010729853.1 | Cys-Gln thioester bond-forming surface protein | - |
| CX663_RS16070 () | 61113..62948 | + | 1836 | WP_010729854.1 | isopeptide-forming domain-containing fimbrial protein | - |
| CX663_RS16075 () | 63017..63880 | + | 864 | WP_025481141.1 | hypothetical protein | VF |
| CX663_RS16080 () | 63870..64949 | + | 1080 | WP_010729856.1 | hypothetical protein | VF |
| CX663_RS16085 () | 65288..66088 | + | 801 | WP_010729857.1 | hypothetical protein | - |
| CX663_RS16090 () | 66176..66982 | + | 807 | WP_101699775.1 | hypothetical protein | - |
| CX663_RS16095 () | 67213..68071 | + | 859 | Protein_84 | hypothetical protein | VF |
| CX663_RS16100 () | 68091..68417 | + | 327 | WP_101699777.1 | hypothetical protein | - |
| CX663_RS16105 () | 68451..69713 | + | 1263 | WP_101699778.1 | hypothetical protein | - |
| CX663_RS16110 () | 69793..71169 | + | 1377 | WP_101699780.1 | DNA translocase FtsK | - |
| CX663_RS16115 () | 71166..71795 | + | 630 | WP_101699782.1 | hypothetical protein | - |
| CX663_RS16120 () | 71807..72265 | + | 459 | WP_101699784.1 | hypothetical protein | - |
| CX663_RS16125 () | 72262..72741 | + | 480 | WP_101699785.1 | hypothetical protein | - |
| CX663_RS16130 () | 72880..73419 | + | 540 | WP_101699787.1 | hypothetical protein | - |
| CX663_RS16665 () | 74070..74123 | + | 54 | Protein_92 | hypothetical protein | - |
| CX663_RS16140 () | 74127..74726 | + | 600 | WP_002347460.1 | rhomboid family intramembrane serine protease | - |
| CX663_RS16145 () | 74742..75218 | + | 477 | WP_002347461.1 | hypothetical protein | - |
| CX663_RS16150 () | 75235..76137 | + | 903 | WP_002347462.1 | hypothetical protein | - |
| CX663_RS16155 () | 76210..76401 | + | 192 | WP_002320847.1 | hypothetical protein | - |
| CX663_RS16160 () | 76565..77152 | + | 588 | WP_002347463.1 | hypothetical protein | - |
| CX663_RS16165 () | 77152..78051 | + | 900 | WP_002347464.1 | RusA family crossover junction endodeoxyribonuclease | - |
| CX663_RS16170 () | 78051..78965 | + | 915 | WP_002347465.1 | hypothetical protein | - |
| CX663_RS16175 () | 79017..79232 | + | 216 | WP_002347466.1 | hypothetical protein | - |
| CX663_RS16180 () | 79418..79630 | + | 213 | WP_101699790.1 | hypothetical protein | - |
| CX663_RS16185 () | 79684..80364 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| CX663_RS16190 () | 80420..80677 | + | 258 | WP_002347171.1 | hypothetical protein | - |
| CX663_RS16195 () | 80775..80984 | + | 210 | WP_000527318.1 | peptide-binding protein | - |
| CX663_RS16200 () | 81001..81273 | + | 273 | WP_000301765.1 | antitoxin | Antitoxin Detail |
| CX663_RS16205 () | 81275..82138 | + | 864 | WP_001284311.1 | toxin zeta | Toxin Detail |
| CX663_RS16210 () | 82401..83138 | - | 738 | WP_001038796.1 | rRNA adenine N-6-methyltransferase | ARG |
| CX663_RS16215 () | 83263..83346 | - | 84 | WP_031929417.1 | 23S rRNA methyltransferase attenuator leader peptide ErmL | - |
| CX663_RS16220 () | 83395..83478 | - | 84 | Protein_109 | peptide-binding protein | - |
| CX663_RS16225 () | 83888..84682 | - | 795 | WP_001096887.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| CX663_RS16230 () | 84775..85026 | - | 252 | Protein_111 | GNAT family N-acetyltransferase | - |
| CX663_RS16235 () | 85271..86566 | + | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| CX663_RS16240 () | 86667..87575 | + | 909 | WP_002324522.1 | IS982 family transposase ISEfm1 | Transposase |
| CX663_RS16245 () | 87578..87826 | - | 249 | WP_002347175.1 | hypothetical protein | - |
| CX663_RS16250 () | 87823..88731 | - | 909 | WP_001255866.1 | Aminoglycoside 6-adenylyltransferase | ARG |
| CX663_RS16255 () | 88764..89498 | - | 735 | WP_000662263.1 | class I SAM-dependent methyltransferase | - |
| CX663_RS16260 () | 89479..90348 | - | 870 | WP_002303392.1 | nucleotidyltransferase domain-containing protein | Toxin Detail |
| CX663_RS16265 () | 90363..90587 | - | 225 | WP_002303393.1 | helix-turn-helix transcriptional regulator | Antitoxin Detail |
| CX663_RS16270 () | 90742..91422 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| CX663_RS16275 () | 91631..91843 | + | 213 | WP_002349227.1 | hypothetical protein | - |
| CX663_RS16280 () | 92005..92523 | + | 519 | WP_000357244.1 | YfbU family protein | - |
| CX663_RS16285 () | 92530..93042 | + | 513 | WP_000774078.1 | hypothetical protein | - |
| CX663_RS16290 () | 93313..93936 | + | 624 | WP_002288897.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| CX663_RS16295 () | 94032..94712 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| CX663_RS16300 () | 94910..95515 | + | 606 | WP_000599739.1 | cell filamentation protein | - |
| CX663_RS16305 () | 95531..96103 | + | 573 | WP_002303206.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| CX663_RS16310 () | 96399..97700 | - | 1302 | WP_002302440.1 | ISL3 family transposase ISEfa11 | Transposase |
| CX663_RS16320 () | 98077..98649 | - | 573 | WP_073120187.1 | IS3 family transposase ISBce13 | Transposase |
| CX663_RS16330 () | 99953..100207 | - | 255 | WP_002322130.1 | IS3 family transposase ISBce13 | Transposase |
| CX663_RS16335 () | 100318..100572 | - | 255 | WP_000199136.1 | IS3 family transposase ISBce13 | Transposase |
| CX663_RS16340 () | 100765..101040 | - | 276 | WP_001196543.1 | hypothetical protein | - |
| CX663_RS16345 () | 101012..101965 | - | 954 | WP_000429439.1 | ParA family protein | - |
| CX663_RS16350 () | 102577..104070 | + | 1494 | WP_000947691.1 | primase C-terminal domain-containing protein | - |
| CX663_RS16355 () | 104205..104519 | + | 315 | WP_002347145.1 | hypothetical protein | - |
| CX663_RS16360 () | 104557..105237 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| CX663_RS16365 () | 105464..106039 | + | 576 | WP_001226076.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| CX663_RS16370 () | 106261..107433 | - | 1173 | WP_002323245.1 | IS256 family transposase IS1542 | Transposase |
| CX663_RS16380 () | 107585..108280 | + | 696 | WP_001280781.1 | Transcriptional regulatory protein WalR | VF |
| CX663_RS16385 () | 108258..109412 | + | 1155 | WP_002305818.1 | VanA-type vancomycin resistance histidine kinase VanS | - |
| CX663_RS16390 () | 109627..110595 | + | 969 | WP_001059542.1 | D-specific alpha-keto acid dehydrogenase | ARG |
| CX663_RS16395 () | 110588..111619 | + | 1032 | WP_001079845.1 | Vancomycin/teicoplanin A-type resistance protein VanA | ARG |
| CX663_RS16400 () | 111625..112233 | + | 609 | WP_000402347.1 | D-alanyl-D-alanine dipeptidase | ARG |
| CX663_RS16405 () | 112409..113089 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| CX663_RS16410 () | 113197..114108 | + | 912 | WP_001812592.1 | D-Ala-D-Ala carboxypeptidase VanY-A | - |
| CX663_RS16415 () | 114261..114746 | + | 486 | WP_000516404.1 | glycopeptide resistance protein VanZ-A | - |
| CX663_RS16420 () | 115033..115362 | - | 330 | WP_000754864.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CX663_RS16425 () | 115667..115996 | + | 330 | WP_000629052.1 | hypothetical protein | - |
| CX663_RS16430 () | 115986..116273 | + | 288 | WP_000312841.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CX663_RS16435 () | 116552..117115 | - | 564 | WP_000017403.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| CX663_RS16440 () | 117308..117880 | - | 573 | WP_002293724.1 | HAD-IIIA family hydrolase | - |
| CX663_RS16445 () | 118668..119243 | + | 576 | WP_002293722.1 | hypothetical protein | - |
| CX663_RS16450 () | 119426..120178 | - | 753 | WP_002325566.1 | IS21 family transposase ISBmu3 | Transposase |
| CX663_RS16455 () | 120178..121719 | - | 1542 | WP_010730990.1 | IS21 family transposase ISSpu5 | Transposase |
| CX663_RS16465 () | 122633..123097 | + | 465 | WP_010730988.1 | DUF5626 family protein | - |
| CX663_RS16470 () | 123094..123618 | - | 525 | WP_079158058.1 | helix-turn-helix transcriptional regulator | - |
| CX663_RS16475 () | 123668..124303 | - | 636 | WP_010730987.1 | Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU | VF |
| CX663_RS16480 () | 124365..125045 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| CX663_RS16485 () | 125349..126392 | + | 1044 | WP_002347500.1 | C39 family peptidase | - |
| CX663_RS16490 () | 126565..126789 | + | 225 | WP_002347499.1 | hypothetical protein | - |
| CX663_RS16495 () | 126792..127049 | + | 258 | WP_025478710.1 | hypothetical protein | - |
| CX663_RS16500 () | 127151..127504 | + | 354 | WP_101699793.1 | hypothetical protein | - |
| CX663_RS16505 () | 127557..128351 | + | 795 | WP_002347496.1 | hypothetical protein | - |
| CX663_RS16510 () | 128380..129498 | + | 1119 | WP_002347495.1 | hypothetical protein | - |
| CX663_RS16515 () | 129531..129851 | + | 321 | WP_002321530.1 | hypothetical protein | - |
| CX663_RS16520 () | 130106..130795 | + | 690 | WP_002347494.1 | hypothetical protein | - |
| CX663_RS16525 () | 130796..130999 | + | 204 | WP_002350561.1 | hypothetical protein | - |
| CX663_RS16530 () | 131019..132647 | + | 1629 | WP_002347493.1 | hypothetical protein | - |
| CX663_RS16535 () | 132698..133069 | + | 372 | WP_002347492.1 | hypothetical protein | - |
| CX663_RS16540 () | 133254..133658 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| CX663_RS16545 () | 133675..134823 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| CX663_RS16550 () | 135045..135245 | + | 201 | WP_002347491.1 | hypothetical protein | - |
| CX663_RS16555 () | 135379..136605 | + | 1227 | WP_002350689.1 | hypothetical protein | - |
| CX663_RS16560 () | 137202..137597 | + | 396 | Protein_174 | type VI secretion protein ImpB | - |
| CX663_RS16825 () | 137675..138714 | + | 1040 | Protein_175 | IS630 family transposase | - |
| CX663_RS16570 () | 138727..139665 | + | 939 | Protein_176 | type VI secretion protein ImpB | - |
| CX663_RS16575 () | 139658..140005 | + | 348 | WP_002347528.1 | hypothetical protein | - |
| CX663_RS16585 () | 140356..141177 | + | 822 | WP_002347527.1 | nucleotidyltransferase domain-containing protein | - |
| CX663_RS16590 () | 141197..141757 | + | 561 | WP_002320756.1 | SLATT domain-containing protein | - |
| CX663_RS16595 () | 142646..142988 | + | 343 | Protein_180 | DNA repair protein RadC | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|