MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 145759 bp
Accession: NZ_CP025212 Location: 1..145759 Organism: Klebsiella pneumoniae strain HZW25 Replicon: plasmid unnamed1
Accession: NZ_CP025212 Location: 1..145759 Organism: Klebsiella pneumoniae strain HZW25 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CW753_RS26205 (CW753_26375) | 2..693 | + | 692 | Protein_0 | hypothetical protein | - |
| CW753_RS26210 (CW753_26380) | 741..1301 | + | 561 | Protein_1 | methyltransferase | - |
| CW753_RS26225 (CW753_26395) | 2135..2677 | + | 543 | WP_032431381.1 | single-stranded DNA-binding protein | - |
| CW753_RS26230 (CW753_26400) | 2726..2974 | + | 249 | WP_032431380.1 | DUF905 domain-containing protein | - |
| CW753_RS26235 (CW753_26405) | 3044..5100 | + | 2057 | Protein_4 | ParB/RepB/Spo0J family partition protein | - |
| CW753_RS26240 (CW753_26410) | 5145..5576 | + | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| CW753_RS26245 (CW753_26415) | 5573..6301 | + | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| CW753_RS26250 (CW753_26420) | 6298..6624 | + | 327 | WP_004194231.1 | hypothetical protein | - |
| CW753_RS26255 (CW753_26425) | 6680..7054 | + | 375 | WP_004182064.1 | hypothetical protein | - |
| CW753_RS26260 (CW753_26430) | 7172..8704 | - | 1533 | WP_004118819.1 | IS3 family transposase ISKpn38 | Transposase |
| CW753_RS26265 (CW753_26435) | 8793..10133 | + | 1341 | WP_000589001.1 | ISNCY family transposase ISCARN112 | Transposase |
| CW753_RS26270 (CW753_26440) | 10497..10679 | + | 183 | Protein_11 | IS110 family transposase ISCps4 | Transposase |
| CW753_RS26275 (CW753_26445) | 10735..11703 | - | 969 | WP_167553401.1 | IS5 family transposase IS903B | Transposase |
| CW753_RS26300 (CW753_26470) | 12537..12950 | - | 414 | WP_004182074.1 | helix-turn-helix domain-containing protein | - |
| CW753_RS26305 (CW753_26475) | 12951..13229 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| CW753_RS26310 (CW753_26480) | 13219..13539 | - | 321 | WP_094833316.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CW753_RS26315 (CW753_26485) | 13620..13844 | - | 225 | WP_020325128.1 | hypothetical protein | - |
| CW753_RS26320 (CW753_26490) | 13855..14067 | - | 213 | WP_020325129.1 | hypothetical protein | - |
| CW753_RS26325 (CW753_26495) | 14128..14484 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| CW753_RS26335 (CW753_26505) | 15120..15470 | - | 351 | WP_004182068.1 | hypothetical protein | - |
| CW753_RS26340 (CW753_26510) | 15467..15739 | - | 273 | WP_023317525.1 | hypothetical protein | - |
| CW753_RS26345 (CW753_26515) | 15929..16414 | + | 486 | WP_020277937.1 | hypothetical protein | - |
| CW753_RS26350 (CW753_26520) | 16579..16680 | - | 102 | Protein_22 | DUF5431 family protein | - |
| CW753_RS30040 | 16644..16736 | - | 93 | Protein_23 | Hok/Gef family protein | - |
| CW753_RS26355 (CW753_26525) | 16796..17830 | + | 1035 | Protein_24 | IS481 family transposase ISKpn28 | Transposase |
| CW753_RS26360 (CW753_26530) | 17897..18184 | - | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin Detail |
| CW753_RS26365 (CW753_26535) | 18184..18423 | - | 240 | WP_000534858.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin Detail |
| CW753_RS30045 | 18448..18552 | + | 105 | Protein_27 | hypothetical protein | - |
| CW753_RS26375 (CW753_26545) | 18686..19609 | - | 924 | WP_020277922.1 | cation diffusion facilitator family transporter | - |
| CW753_RS26380 (CW753_26550) | 19809..20381 | - | 573 | WP_001515348.1 | cytochrome b/b6 domain-containing protein | - |
| CW753_RS26385 (CW753_26555) | 20857..21975 | - | 1119 | Protein_30 | IS110 family transposase ISCps4 | Transposase |
| CW753_RS26390 (CW753_26560) | 22036..23004 | - | 969 | WP_077257689.1 | IS5 family transposase IS903B | Transposase |
| CW753_RS26395 (CW753_26565) | 23038..27669 | + | 4632 | Protein_32 | Multifunctional conjugation protein TraI | Relaxase |
| CW753_RS26400 (CW753_26570) | 27759..28484 | + | 726 | WP_040088251.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| CW753_RS26405 (CW753_26575) | 28556..29152 | + | 597 | WP_040088253.1 | fertility inhibition protein FinO | - |
| CW753_RS26410 (CW753_26580) | 29172..29519 | + | 348 | WP_040088254.1 | DUF6404 family protein | - |
| CW753_RS26415 (CW753_26585) | 29990..30634 | + | 645 | WP_040088255.1 | hypothetical protein | - |
| CW753_RS26420 (CW753_26590) | 30631..30741 | + | 111 | WP_071830736.1 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| CW753_RS26425 (CW753_26595) | 31013..32404 | - | 1392 | WP_040088256.1 | FAD-dependent oxidoreductase | - |
| CW753_RS26430 (CW753_26600) | 32401..32700 | - | 300 | WP_008103233.1 | (2Fe-2S)-binding protein | - |
| CW753_RS26435 (CW753_26605) | 32684..33811 | - | 1128 | WP_040088258.1 | FAD-dependent oxidoreductase | - |
| CW753_RS26440 (CW753_26610) | 34562..35350 | + | 789 | WP_134906156.1 | transporter substrate-binding domain-containing protein | - |
| CW753_RS26445 (CW753_26615) | 35372..36340 | + | 969 | WP_167553402.1 | IS5 family transposase IS903B | Transposase |
| CW753_RS26450 (CW753_26620) | 36462..37994 | + | 1533 | WP_015065592.1 | IS3 family transposase ISKpn38 | Transposase |
| CW753_RS26455 (CW753_26625) | 38153..38635 | - | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| CW753_RS26460 (CW753_26630) | 38623..38889 | - | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| CW753_RS26470 (CW753_26640) | 39334..39564 | - | 231 | WP_004206660.1 | hypothetical protein | - |
| CW753_RS26475 (CW753_26645) | 39578..39781 | - | 204 | WP_004213596.1 | HHA domain-containing protein | - |
| CW753_RS26480 (CW753_26650) | 39842..40333 | - | 492 | WP_015065591.1 | hypothetical protein | - |
| CW753_RS26485 (CW753_26655) | 40467..41501 | - | 1035 | WP_015065590.1 | hypothetical protein | - |
| CW753_RS26490 (CW753_26660) | 41803..42807 | - | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| CW753_RS26495 (CW753_26665) | 42886..44850 | - | 1965 | Protein_51 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| CW753_RS26505 (CW753_26680) | 45615..45824 | + | 210 | WP_077255705.1 | HTH-type transcriptional regulator PgrR | VF |
| CW753_RS26510 (CW753_26685) | 45893..46801 | - | 909 | WP_032413424.1 | LysR family transcriptional regulator | - |
| CW753_RS26515 (CW753_26690) | 47373..48194 | - | 822 | WP_015065586.1 | M55 family metallopeptidase | - |
| CW753_RS26520 (CW753_26695) | 48191..49234 | - | 1044 | WP_057058099.1 | P1 family peptidase | - |
| CW753_RS26525 (CW753_26700) | 49237..50106 | - | 870 | WP_015065584.1 | ABC transporter permease subunit | - |
| CW753_RS26530 (CW753_26705) | 50103..51035 | - | 933 | WP_015065583.1 | ABC transporter permease subunit | - |
| CW753_RS26535 (CW753_26710) | 51117..52658 | - | 1542 | WP_032413310.1 | glutathione ABC transporter substrate-binding protein | - |
| CW753_RS26540 (CW753_26715) | 52681..54546 | - | 1866 | WP_015065581.1 | Glutathione import ATP-binding protein GsiA | VF |
| CW753_RS26545 (CW753_26720) | 54562..55527 | - | 966 | WP_023328925.1 | L-Ala-D/L-Glu epimerase | - |
| CW753_RS26550 (CW753_26725) | 55529..56536 | - | 1008 | WP_032413314.1 | DUF1611 domain-containing protein | - |
| CW753_RS26555 (CW753_26730) | 56928..57317 | - | 390 | WP_015065578.1 | tautomerase family protein | - |
| CW753_RS26560 (CW753_26735) | 57437..58357 | + | 921 | WP_064175841.1 | HTH-type transcriptional regulator DmlR | VF |
| CW753_RS26565 (CW753_26740) | 58666..59647 | + | 982 | WP_000019450.1 | IS5 family transposase ISKpn26 | Transposase |
| CW753_RS26575 (CW753_26745) | 59796..60014 | + | 219 | Protein_66 | IS5 family transposase IS903 | Transposase |
| CW753_RS29645 | 60056..60199 | - | 144 | WP_159194436.1 | hypothetical protein | - |
| CW753_RS26580 (CW753_26750) | 60243..60737 | - | 495 | WP_013023776.1 | hypothetical protein | - |
| CW753_RS26585 (CW753_26755) | 60768..61334 | - | 567 | WP_013023777.1 | hypothetical protein | - |
| CW753_RS26590 (CW753_26760) | 61331..61594 | - | 264 | WP_064175861.1 | hypothetical protein | - |
| CW753_RS26595 (CW753_26765) | 61952..62302 | + | 351 | WP_004206664.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| CW753_RS26600 (CW753_26770) | 62354..62716 | + | 363 | WP_004206665.1 | arsenite efflux transporter metallochaperone ArsD | - |
| CW753_RS26605 (CW753_26775) | 62734..64485 | + | 1752 | WP_016151356.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| CW753_RS26610 (CW753_26780) | 64533..65822 | + | 1290 | WP_023292114.1 | arsenite efflux transporter membrane subunit ArsB | - |
| CW753_RS26615 (CW753_26785) | 65835..66260 | + | 426 | WP_007779002.1 | glutaredoxin-dependent arsenate reductase | - |
| CW753_RS26620 (CW753_26790) | 66293..66538 | - | 246 | Protein_76 | N-acetyltransferase | - |
| CW753_RS26625 (CW753_26795) | 66578..68116 | - | 1539 | WP_023290558.1 | IS66 family transposase ISKpn24 | Transposase |
| CW753_RS26630 (CW753_26800) | 68165..68512 | - | 348 | WP_080816676.1 | IS66 family transposase ISKpn24 | Transposase |
| CW753_RS26635 (CW753_26805) | 68509..68913 | - | 405 | WP_094326334.1 | IS66 family transposase ISKpn24 | Transposase |
| CW753_RS26640 (CW753_26815) | 69018..69116 | + | 99 | WP_004118688.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CW753_RS30050 (CW753_26820) | 69153..69315 | + | 163 | Protein_81 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CW753_RS26650 (CW753_26825) | 69495..69929 | - | 435 | WP_064175764.1 | copper resistance system metallochaperone PcoE | - |
| CW753_RS26655 (CW753_26830) | 70146..71546 | - | 1401 | Protein_83 | copper resistance membrane spanning protein PcoS | - |
| CW753_RS26660 (CW753_26835) | 71543..72223 | - | 681 | WP_009309896.1 | Transcriptional activator protein CopR | VF |
| CW753_RS26665 (CW753_26840) | 72278..73207 | - | 930 | WP_000998778.1 | copper resistance inner membrane protein PcoD | - |
| CW753_RS26670 (CW753_26845) | 73212..73592 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| CW753_RS26675 (CW753_26850) | 73632..74522 | - | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| CW753_RS26680 (CW753_26855) | 74528..76344 | - | 1817 | Protein_88 | multicopper oxidase PcoA | - |
| CW753_RS26685 (CW753_26860) | 76578..77027 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| CW753_RS26690 (CW753_26865) | 77316..78053 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| CW753_RS26695 (CW753_26870) | 78087..78284 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| CW753_RS26700 (CW753_26875) | 78325..80772 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| CW753_RS26705 (CW753_26880) | 80899..81339 | - | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| CW753_RS26710 (CW753_26885) | 81426..84572 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| CW753_RS26715 (CW753_26890) | 84583..85875 | - | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| CW753_RS26720 (CW753_26895) | 85989..86342 | - | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| CW753_RS26725 (CW753_26900) | 86371..87756 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| CW753_RS26730 (CW753_26905) | 87946..88626 | + | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| CW753_RS26735 (CW753_26910) | 88619..90094 | + | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| CW753_RS26740 (CW753_26915) | 90345..90776 | + | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| CW753_RS26745 (CW753_26920) | 91072..91614 | - | 543 | Protein_101 | ISL3 family transposase ISKpn25 | Transposase |
| CW753_RS26750 (CW753_26925) | 91630..92114 | - | 485 | Protein_102 | IS1 family transposase IS1X2 | Transposase |
| CW753_RS26755 (CW753_26930) | 92205..93412 | + | 1208 | WP_085955172.1 | IS3 family transposase ISEcl1 | Transposase |
| CW753_RS26760 (CW753_26940) | 93603..94300 | + | 698 | WP_223174975.1 | IS1 family transposase IS1X2 | Transposase |
| CW753_RS26765 (CW753_26945) | 94354..95946 | - | 1593 | WP_040216213.1 | IS66 family transposase ISKox1 | Transposase |
| CW753_RS26770 (CW753_26950) | 95977..96327 | - | 351 | WP_004189161.1 | IS66 family transposase ISKox1 | Transposase |
| CW753_RS26775 (CW753_26955) | 96324..96764 | - | 441 | WP_004189163.1 | IS66 family transposase ISKox1 | Transposase |
| CW753_RS26780 (CW753_26960) | 96986..98983 | + | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| CW753_RS26785 (CW753_26965) | 99046..100323 | + | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| CW753_RS26790 (CW753_26970) | 101306..101866 | - | 561 | Protein_110 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| CW753_RS26795 (CW753_26975) | 101901..102869 | + | 969 | WP_077257689.1 | IS5 family transposase IS903B | Transposase |
| CW753_RS26800 (CW753_26980) | 102915..103787 | - | 873 | WP_265735877.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| CW753_RS26805 (CW753_26985) | 104459..105426 | - | 968 | Protein_113 | IS5 family transposase IS903B | Transposase |
| CW753_RS26810 (CW753_26990) | 105494..105751 | + | 258 | WP_004197688.1 | hypothetical protein | - |
| CW753_RS26815 (CW753_26995) | 106424..107391 | - | 968 | Protein_115 | IS5 family transposase IS903B | Transposase |
| CW753_RS26825 (CW753_27005) | 107480..107635 | + | 156 | WP_194433545.1 | EAL domain-containing protein | - |
| CW753_RS26830 (CW753_27010) | 107748..108695 | - | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| CW753_RS26835 (CW753_27015) | 109839..110579 | + | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| CW753_RS26840 (CW753_27020) | 111297..112307 | - | 1011 | WP_004182030.1 | RepB family plasmid replication initiator protein | - |
| CW753_RS26845 (CW753_27025) | 113059..114225 | + | 1167 | WP_004182032.1 | Sporulation initiation inhibitor protein Soj | VF |
| CW753_RS26850 (CW753_27030) | 114225..115196 | + | 972 | WP_004182039.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| CW753_RS26860 (CW753_27040) | 116067..117183 | + | 1117 | Protein_122 | IS3 family transposase ISSen4 | Transposase |
| CW753_RS30195 | 117961..118206 | - | 246 | WP_000055351.1 | IS1 family transposase IS1A | Transposase |
| CW753_RS30200 | 118381..118656 | - | 276 | WP_000179213.1 | IS1-like element transposase | - |
| CW753_RS26870 (CW753_27055) | 118698..119114 | + | 417 | WP_196530244.1 | hypothetical protein | - |
| CW753_RS26875 (CW753_27060) | 119624..120904 | + | 1281 | WP_016246209.1 | DUF262 domain-containing protein | - |
| CW753_RS26880 (CW753_27065) | 120901..122853 | + | 1953 | WP_000037308.1 | DUF262 domain-containing protein | - |
| CW753_RS26885 (CW753_27070) | 123098..123349 | - | 252 | WP_004182043.1 | hypothetical protein | - |
| CW753_RS26890 (CW753_27075) | 123428..124699 | - | 1272 | WP_023157784.1 | Y-family DNA polymerase | - |
| CW753_RS26895 (CW753_27080) | 124699..125124 | - | 426 | WP_004182047.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CW753_RS26905 (CW753_27090) | 125526..127037 | + | 1512 | WP_160525772.1 | Group II intron-encoded protein LtrA | VF |
| CW753_RS26910 (CW753_27095) | 127271..127501 | + | 231 | WP_004118481.1 | hypothetical protein | - |
| CW753_RS26920 (CW753_27105) | 128021..128446 | + | 426 | WP_004118478.1 | antirestriction protein | - |
| CW753_RS26925 (CW753_27110) | 128683..128937 | + | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| CW753_RS26930 (CW753_27115) | 128972..129289 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| CW753_RS26935 (CW753_27120) | 130016..130243 | + | 228 | WP_004182050.1 | hypothetical protein | - |
| CW753_RS26940 (CW753_27125) | 130335..130565 | + | 231 | WP_032433725.1 | hypothetical protein | - |
| CW753_RS26945 (CW753_27130) | 130617..131971 | + | 1355 | Protein_138 | DUF3560 domain-containing protein | - |
| CW753_RS26950 (CW753_27135) | 132019..132582 | + | 564 | WP_004182054.1 | methyltransferase | - |
| CW753_RS26965 (CW753_27150) | 133417..133959 | + | 543 | WP_032431381.1 | single-stranded DNA-binding protein | - |
| CW753_RS26970 (CW753_27155) | 134008..134256 | + | 249 | WP_032431380.1 | DUF905 domain-containing protein | - |
| CW753_RS26975 (CW753_27160) | 134326..136383 | + | 2058 | WP_020277924.1 | ParB/RepB/Spo0J family partition protein | - |
| CW753_RS26980 (CW753_27165) | 136428..136859 | + | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| CW753_RS26985 (CW753_27170) | 136856..137584 | + | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| CW753_RS26990 (CW753_27175) | 137581..137907 | + | 327 | WP_004194231.1 | hypothetical protein | - |
| CW753_RS26995 (CW753_27180) | 137963..138337 | + | 375 | WP_004182064.1 | hypothetical protein | - |
| CW753_RS27000 (CW753_27185) | 138455..139987 | - | 1533 | WP_004118819.1 | IS3 family transposase ISKpn38 | Transposase |
| CW753_RS27005 (CW753_27190) | 140076..141416 | + | 1341 | WP_000589001.1 | ISNCY family transposase ISCARN112 | Transposase |
| CW753_RS27010 (CW753_27195) | 141780..141961 | + | 182 | Protein_149 | IS110 family transposase | - |
| CW753_RS27015 (CW753_27200) | 142016..142984 | - | 969 | WP_167553401.1 | IS5 family transposase IS903B | Transposase |
| CW753_RS27030 (CW753_27215) | 143834..144232 | - | 399 | Protein_151 | helix-turn-helix domain-containing protein | - |
| CW753_RS27035 (CW753_27220) | 144233..144511 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| CW753_RS27040 (CW753_27225) | 144501..144821 | - | 321 | WP_094833316.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CW753_RS27045 (CW753_27230) | 144902..145048 | - | 147 | WP_209300257.1 | hypothetical protein | - |
| CW753_RS27050 (CW753_27235) | 145136..145348 | - | 213 | WP_020325129.1 | hypothetical protein | - |
| CW753_RS27055 (CW753_27240) | 145409..145695 | - | 287 | Protein_156 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|