NZ_CP0241401..166233

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 166233 bp
Accession: NZ_CP024140        Location: 1..166233         Organism: Escherichia coli strain 14EC020       Replicon: plasmid p14EC020b


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR537_RS25875 () 127..420 + 294 WP_000738422.1 increased serum survival lipoprotein Iss -
CR537_RS25880 () 478..677 - 200 Protein_1 lysis system i-spanin subunit Rz -
CR537_RS25890 () 1231..2330 + 1100 Protein_2 IS481 family transposase ISKpn28 Transposase
CR537_RS25900 () 3566..4681 + 1116 WP_001318220.1 Elloramycin glycosyltransferase ElmGT VF
CR537_RS25905 () 4821..8480 + 3660 WP_001111199.1 Multidrug efflux ATP-binding/permease protein VF
CR537_RS25910 () 8584..9813 + 1230 WP_001552738.1 Enterochelin esterase VF
CR537_RS25915 () 9898..10854 + 957 WP_000271276.1 Ferri-bacillibactin esterase BesA VF
CR537_RS25920 () 10899..13076 - 2178 WP_001222186.1 Ferric enterobactin receptor VF
CR537_RS25925 () 13411..14108 - 698 Protein_8 IS1 family transposase -
CR537_RS27200 () 14160..14234 - 75 Protein_9 colicin -
CR537_RS27205 () 14212..14448 - 237 WP_014640552.1 colicin V immunity protein -
CR537_RS25940 () 14912..15193 - 282 WP_001105066.1 hypothetical protein -
CR537_RS25945 () 15366..15533 + 168 Protein_12 colicin-B -
CR537_RS25950 () 15551..16078 - 528 WP_000203272.1 colicin B immunity protein -
CR537_RS25960 () 16322..17137 + 816 WP_001312845.1 lipid II-degrading bacteriocin colicin M -
CR537_RS25965 () 17187..17540 - 354 WP_000864812.1 colicin M immunity protein -
CR537_RS25970 () 17718..18509 - 792 WP_000016493.1 site-specific integrase -
CR537_RS25975 () 18506..19195 - 690 WP_000796228.1 hypothetical protein -
CR537_RS25980 () 19239..19589 - 351 WP_000493380.1 hypothetical protein -
CR537_RS25985 () 20271..21266 + 996 WP_000246635.1 hypothetical protein -
CR537_RS25990 () 21270..22202 + 933 WP_000991830.1 hypothetical protein -
CR537_RS25995 () 22500..23588 + 1089 WP_000952231.1 hypothetical protein -
CR537_RS26000 () 23590..24459 + 870 WP_000253407.1 hypothetical protein -
CR537_RS26005 () 24516..26081 - 1566 WP_000741348.1 ATP-binding protein -
CR537_RS26015 () 26389..26619 + 231 WP_001261287.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
CR537_RS26020 () 26616..27032 + 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
CR537_RS26025 () 27194..29332 - 2139 WP_000350635.1 AAA family ATPase -
CR537_RS26030 () 29686..29943 + 258 WP_000343085.1 hypothetical protein -
CR537_RS26035 () 29943..30533 + 591 WP_000194575.1 hypothetical protein -
CR537_RS26040 () 30796..32352 + 1557 WP_024126035.1 AAA family ATPase -
CR537_RS26045 () 32542..33159 + 618 WP_000521603.1 hypothetical protein -
CR537_RS26050 () 33452..34531 - 1080 WP_063117293.1 permease -
CR537_RS26055 () 34636..34959 + 324 WP_001175594.1 helix-turn-helix domain-containing protein -
CR537_RS26060 () 35060..35440 + 381 Protein_33 NAD(P)H-dependent oxidoreductase -
CR537_RS26065 () 35493..36197 - 705 WP_001067834.1 IS6 family transposase IS26 Transposase
CR537_RS26070 () 36263..37702 + 1440 Protein_35 Tn3 family transposase TnpA_TnAs1 Transposase
CR537_RS26075 () 37657..38361 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CR537_RS26085 () 38427..38711 + 285 Protein_37 IS6 family transposase IS26 Transposase
CR537_RS26090 () 38901..39716 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
CR537_RS26095 () 39867..40571 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CR537_RS26105 () 40618..40686 + 69 Protein_40 macrolide transporter -
CR537_RS26110 () 40832..41695 + 864 WP_000612791.1 SDR family oxidoreductase -
CR537_RS26115 () 41733..41978 + 246 WP_001354008.1 GrpB family protein -
CR537_RS26120 () 42447..43238 + 792 WP_000034420.1 Dihydropteroate synthase ARG
CR537_RS27355 () 43241..43516 - 276 WP_109023896.1 hypothetical protein -
CR537_RS26125 () 43518..44153 + 636 Protein_45 IS256 family transposase IS406 Transposase
CR537_RS26135 () 44402..44875 - 474 Protein_46 HAD-IB family hydrolase -
CR537_RS26140 () 44929..45633 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CR537_RS26145 () 45703..46176 - 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
CR537_RS26150 () 46332..47216 + 885 Protein_49 IS91 family transposase ISAzo26 Transposase
CR537_RS26155 () 47278..47982 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
CR537_RS26160 () 48035..48466 - 432 Protein_51 Tn3 family transposase TnpR_TnAs3 Transposase
CR537_RS27210 () 48592..48942 - 351 WP_000454193.1 DUF3330 domain-containing protein -
CR537_RS26170 () 49145..50158 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
CR537_RS26175 () 50325..51167 + 843 WP_001456218.1 alpha/beta fold putative hydrolase EstX -
CR537_RS26190 () 51468..52172 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CR537_RS27215 () 52178..52318 + 141 WP_001044210.1 hypothetical protein -
CR537_RS26200 () 52804..53541 + 738 WP_001366550.1 Tn3 family transposase TnpR_TnEc1 Transposase
CR537_RS26205 () 53538..53762 + 225 WP_000743213.1 hypothetical protein -
CR537_RS26210 () 53973..55466 + 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
CR537_RS27360 () 55935..56381 + 447 Protein_60 DUF3363 domain-containing protein -
CR537_RS26220 () 56598..57812 + 1215 WP_000214121.1 Bicyclomycin resistance protein ARG
CR537_RS26225 () 57840..58145 + 306 WP_001255015.1 HTH-type transcriptional regulator CynR VF
CR537_RS26230 () 58257..58445 + 189 Protein_63 IS91 family transposase -
CR537_RS26235 () 58412..59611 - 1200 WP_000804063.1 Tetracycline resistance protein, class C ARG
CR537_RS26240 () 59717..60367 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
CR537_RS26245 () 60399..60641 - 243 WP_000844627.1 transposase -
CR537_RS26255 () 60947..61783 - 837 WP_000480968.1 hypothetical protein ARG
CR537_RS26260 () 61783..62586 - 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
CR537_RS26265 () 62647..63462 - 816 WP_001043260.1 Dihydropteroate synthase ARG
CR537_RS26270 () 63624..64484 - 861 WP_000027057.1 Beta-lactamase TEM ARG
CR537_RS26275 () 64667..65152 - 486 Protein_71 Tn3 family transposase TnpR_Tn3 Transposase
CR537_RS26280 () 65196..65900 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CR537_RS26285 () 65937..67064 - 1128 WP_014837927.1 DUF3883 domain-containing protein -
CR537_RS26290 () 67115..67342 - 228 WP_000248278.1 hypothetical protein -
CR537_RS26295 () 67366..67557 + 192 WP_000951934.1 hypothetical protein -
CR537_RS26300 () 68039..68581 - 543 WP_000587837.1 AAA family ATPase -
CR537_RS26305 () 68594..69454 - 861 WP_000557454.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
CR537_RS26315 () 69597..70502 + 906 Protein_78 IS4 family transposase IS10R Transposase
CR537_RS26320 () 70551..71255 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
CR537_RS26325 () 71314..74313 + 3000 WP_072834372.1 Tn3 family transposase TnpA_Tn3 Transposase
CR537_RS26330 () 74347..74436 - 90 Protein_81 mercuric transport protein -
CR537_RS26335 () 74508..74942 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
CR537_RS26345 () 75338..75739 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
CR537_RS27220 () 75672..75929 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
CR537_RS26350 () 76022..76675 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
CR537_RS26360 () 77397..77822 + 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
CR537_RS26365 () 77819..78169 + 351 WP_000624717.1 IS66 family transposase IS682 Transposase
CR537_RS26370 () 78200..79792 + 1593 WP_001593684.1 IS66 family transposase ISEc23 Transposase
CR537_RS26375 () 79888..80235 - 348 WP_000612556.1 IS66 family transposase ISEc8 Transposase
CR537_RS26380 () 80232..80612 - 381 WP_001171523.1 IS66 family transposase ISEc8 Transposase
CR537_RS26390 () 81389..82246 - 858 WP_000774297.1 incFII family plasmid replication initiator RepA -
CR537_RS26395 () 82239..82721 - 483 WP_181726436.1 hypothetical protein -
CR537_RS26400 () 82714..82788 - 75 WP_001442103.1 RepA leader peptide Tap -
CR537_RS26410 () 83020..83277 - 258 WP_000083845.1 replication regulatory protein RepA -
CR537_RS26415 () 83561..83767 - 207 WP_001351576.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 83754..83815 + 62 NuclAT_1 - Antitoxin Detail
- () 83754..83815 + 62 NuclAT_1 - Antitoxin Detail
- () 83754..83815 + 62 NuclAT_1 - Antitoxin Detail
- () 83754..83815 + 62 NuclAT_1 - Antitoxin Detail
CR537_RS27365 () 84071..84145 - 75 Protein_96 endonuclease -
CR537_RS26425 () 84391..84603 - 213 WP_001299730.1 ANR family transcriptional regulator -
CR537_RS26430 () 84739..85299 - 561 WP_000139315.1 fertility inhibition protein FinO -
CR537_RS26435 () 85402..86262 - 861 WP_000704514.1 putative protein YcjY VF
CR537_RS26440 () 86321..87067 - 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
CR537_RS26445 () 87087..92357 - 5271 WP_000986962.1 Multifunctional conjugation protein TraI Relaxase
CR537_RS26450 () 92439..92666 + 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
CR537_RS26455 () 92666..93064 + 399 WP_000911313.1 tRNA(fMet)-specific endonuclease VapC Toxin Detail
CR537_RS26460 () 93073..95226 - 2154 WP_000009324.1 type IV conjugative transfer system coupling protein TraD -
CR537_RS26465 () 95479..96210 - 732 WP_023565183.1 complement resistance protein TraT -
CR537_RS26470 () 96242..96739 - 498 WP_000605857.1 entry exclusion protein -
CR537_RS26475 () 96755..99577 - 2823 WP_001007018.1 conjugal transfer mating pair stabilization protein TraG -
CR537_RS26480 () 99574..100947 - 1374 WP_001517790.1 conjugal transfer protein TraH -
CR537_RS26485 () 100947..101360 - 414 WP_001324104.1 F-type conjugal transfer protein TrbF -
CR537_RS26490 () 101314..101655 - 342 WP_001443031.1 P-type conjugative transfer protein TrbJ -
CR537_RS26495 () 101585..102130 - 546 WP_000059851.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CR537_RS26500 () 102117..102401 - 285 WP_000624109.1 type-F conjugative transfer system pilin chaperone TraQ -
CR537_RS26505 () 102482..102796 + 315 WP_001324103.1 hypothetical protein -
CR537_RS26510 () 102798..103145 - 348 WP_001287910.1 conjugal transfer protein TrbA -
CR537_RS26515 () 103161..103904 - 744 WP_001030393.1 type-F conjugative transfer system pilin assembly protein TraF -
CR537_RS26520 () 103897..104154 - 258 WP_000864318.1 conjugal transfer protein TrbE -
CR537_RS26525 () 104181..105989 - 1809 WP_000821841.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CR537_RS26530 () 105986..106624 - 639 WP_000777700.1 type-F conjugative transfer system pilin assembly protein TrbC -
CR537_RS26535 () 106633..107625 - 993 WP_000830183.1 conjugal transfer pilus assembly protein TraU -
CR537_RS26540 () 107622..108254 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
CR537_RS26545 () 108251..108637 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
CR537_RS26550 () 108634..111261 - 2628 WP_001064245.1 type IV secretion system protein TraC -
CR537_RS26555 () 111421..111642 - 222 WP_001278689.1 conjugal transfer protein TraR -
CR537_RS26560 () 111777..112292 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
CR537_RS26565 () 112289..112540 - 252 WP_001038342.1 conjugal transfer protein TrbG -
CR537_RS27370 () 112552..112701 - 150 WP_101980575.1 conjugal transfer protein TrbD -
CR537_RS26585 () 113997..114587 - 591 WP_001376242.1 conjugal transfer protein TraP -
CR537_RS26590 () 114577..116004 - 1428 WP_000146685.1 conjugal transfer protein TraB -
CR537_RS26595 () 116004..116708 - 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
CR537_RS26600 () 116719..117285 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
CR537_RS26605 () 117307..117618 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
CR537_RS26610 () 117633..117998 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
CR537_RS26615 () 118031..118426 - 396 WP_001309237.1 conjugal transfer relaxosome protein TraY -
CR537_RS26620 () 118525..119214 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
CR537_RS26625 () 119401..119784 - 384 WP_001151524.1 relaxosome protein TraM -
CR537_RS26630 () 120105..120707 + 603 WP_000243712.1 hypothetical protein VF
CR537_RS26635 () 121004..121825 - 822 WP_001234426.1 DUF945 domain-containing protein -
CR537_RS26640 () 121943..122230 - 288 WP_000107535.1 hypothetical protein -
CR537_RS26655 () 123151..123309 - 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 123353..123577 - 225 NuclAT_0 - Antitoxin Detail
- () 123353..123577 - 225 NuclAT_0 - Antitoxin Detail
- () 123353..123577 - 225 NuclAT_0 - Antitoxin Detail
- () 123353..123577 - 225 NuclAT_0 - Antitoxin Detail
CR537_RS27225 () 123389..123577 + 189 WP_001299721.1 hypothetical protein -
CR537_RS26660 () 123589..124308 - 720 WP_001276238.1 plasmid SOS inhibition protein A -
CR537_RS26665 () 124305..124739 - 435 WP_000845936.1 conjugation system SOS inhibitor PsiB -
CR537_RS26670 () 124794..124991 - 198 Protein_144 hypothetical protein -
CR537_RS26675 () 125019..125252 - 234 WP_000005987.1 DUF905 family protein -
CR537_RS26680 () 125320..125859 - 540 WP_000290840.1 single-stranded DNA-binding protein -
CR537_RS27375 () 125885..126091 - 207 WP_000275856.1 hypothetical protein -
CR537_RS26705 () 127230..128201 - 972 WP_000817028.1 ParB/RepB/Spo0J family plasmid partition protein -
CR537_RS26710 () 128201..129367 - 1167 WP_001238646.1 Sporulation initiation inhibitor protein Soj VF
CR537_RS26715 () 129667..130364 - 698 Protein_150 IS1 family transposase IS1S Transposase
CR537_RS26730 () 130849..133050 - 2202 WP_000973520.1 Ferric aerobactin receptor VF
CR537_RS26735 () 133132..134409 - 1278 WP_000750130.1 L-lysine N6-monooxygenase VF
CR537_RS26740 () 134406..136148 - 1743 WP_001015721.1 Aerobactin synthase VF
CR537_RS26745 () 136148..137095 - 948 WP_000011910.1 N(6)-hydroxylysine O-acetyltransferase VF
CR537_RS26750 () 137096..138820 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
CR537_RS26755 () 138956..140149 + 1194 WP_000095526.1 MFS transporter -
CR537_RS26760 () 140529..140909 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
CR537_RS26770 () 141250..141663 - 414 Protein_158 phosphopyruvate hydratase -
CR537_RS26780 () 142152..143009 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
CR537_RS26785 () 143006..143863 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
CR537_RS26790 () 143860..144687 - 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
CR537_RS26795 () 144687..145601 - 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
CR537_RS26810 () 145957..146654 + 698 Protein_163 IS1 family transposase IS1S Transposase
CR537_RS26815 () 146834..147347 - 514 Protein_164 DUF4113 domain-containing protein -
CR537_RS27380 () 147408..147512 - 105 Protein_165 AAA family ATPase -
CR537_RS26825 () 147514..147837 - 324 Protein_166 IS21 family transposase IS21 Transposase
CR537_RS26835 () 148583..149560 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
CR537_RS26840 () 149845..150585 - 741 WP_001066954.1 tyrosine-type recombinase/integrase -
CR537_RS26845 () 150706..150894 - 189 WP_065203495.1 serine/threonine protein kinase -
CR537_RS26850 () 151268..152170 - 903 WP_001312822.1 hypothetical protein VF
CR537_RS26855 () 152239..153348 - 1110 WP_000771475.1 SDR family oxidoreductase -
CR537_RS26865 () 153781..154734 - 954 WP_000280980.1 Protease 7 VF
CR537_RS26880 () 156007..156165 - 159 WP_001312823.1 integrase core domain-containing protein -
CR537_RS26885 () 156349..156651 + 303 Protein_174 IS3 family transposase IS1203 Transposase
CR537_RS26890 () 156707..157404 + 698 Protein_175 IS1 family transposase IS1G Transposase
CR537_RS26895 () 157398..157679 - 282 WP_072834405.1 hypothetical protein -
CR537_RS26900 () 157820..159646 - 1827 WP_001339650.1 AAA family ATPase -
CR537_RS26905 () 159649..160134 - 486 WP_001015823.1 hypothetical protein -
CR537_RS26910 () 160124..161224 - 1101 WP_072714138.1 hypothetical protein -
CR537_RS26915 () 161754..161903 - 150 Protein_180 IS3 family transposase IS2 Transposase
CR537_RS26920 () 162081..163274 - 1194 WP_000450494.1 GTP-binding protein -
CR537_RS26930 () 164497..165733 - 1237 Protein_182 IS3 family transposase IS2 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance