MGE detailed information

MGE type: Conjugative plasmid        MGE length: 152425 bp
Accession: NZ_CP023835        Location: 1..152425         Organism: Escherichia coli strain 4/2-1       Replicon: plasmid p4_2_1.1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRT37_RS22810 () 1..756 + 756 WP_000852146.1 replication initiation protein RepE -
CRT37_RS22815 () 1344..2510 + 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
CRT37_RS22820 () 2510..3481 + 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
CRT37_RS22830 () 4219..5121 + 903 WP_064766247.1 DUF1281 domain-containing protein -
CRT37_RS22835 () 5125..5429 + 305 Protein_4 hypothetical protein -
CRT37_RS22840 () 5506..6189 + 684 WP_032181561.1 DNA methylase -
CRT37_RS22845 () 6190..6411 + 222 WP_001104873.1 hypothetical protein -
CRT37_RS22850 () 6425..6859 + 435 WP_001546462.1 DUF1380 family protein -
CRT37_RS22855 () 6904..7674 + 771 WP_001006251.1 hypothetical protein -
CRT37_RS22870 () 8211..8513 + 303 WP_001666994.1 antirestriction protein -
CRT37_RS22875 () 8560..8982 + 423 WP_000271685.1 DUF1380 family protein -
CRT37_RS22880 () 8979..9170 + 192 WP_001027495.1 hypothetical protein -
CRT37_RS24275 () 9442..9690 - 249 WP_071781657.1 hypothetical protein -
CRT37_RS22890 () 10202..10432 + 231 WP_000218642.1 hypothetical protein -
CRT37_RS22895 () 10484..11845 + 1362 WP_000199439.1 DUF3560 domain-containing protein -
CRT37_RS22900 () 11893..12458 + 566 Protein_15 class I SAM-dependent methyltransferase -
CRT37_RS22905 () 12484..12696 + 213 WP_001348622.1 hypothetical protein -
CRT37_RS24385 () 13106..13312 + 207 WP_000275856.1 hypothetical protein -
CRT37_RS22930 () 13990..15891 + 1902 WP_000936285.1 group II intron reverse transcriptase/maturase -
CRT37_RS22935 () 16041..16538 + 498 WP_042039995.1 single-stranded DNA-binding protein -
CRT37_RS22940 () 16606..16839 + 234 WP_000005990.1 DUF905 family protein -
CRT37_RS22945 () 16867..17064 + 198 Protein_21 hypothetical protein -
CRT37_RS22950 () 17119..17553 + 435 WP_000845937.1 conjugation system SOS inhibitor PsiB -
CRT37_RS22955 () 17550..18269 + 720 WP_001276238.1 plasmid SOS inhibition protein A -
CRT37_RS24280 () 18281..18469 - 189 WP_001299721.1 hypothetical protein -
- () 18281..18478 + 198 NuclAT_0 - -
- () 18281..18478 + 198 NuclAT_0 - -
- () 18281..18478 + 198 NuclAT_0 - -
- () 18281..18478 + 198 NuclAT_0 - -
CRT37_RS22960 () 18526..19895 + 1370 WP_085947770.1 IS3 family transposase IS150 Transposase
- () 19920..19951 + 32 NuclAT_1 - Antitoxin Detail
- () 19920..19951 + 32 NuclAT_1 - Antitoxin Detail
- () 19920..19951 + 32 NuclAT_1 - Antitoxin Detail
- () 19920..19951 + 32 NuclAT_1 - Antitoxin Detail
CRT37_RS22965 () 19995..20153 + 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
CRT37_RS22980 () 21074..21361 + 288 WP_000107535.1 hypothetical protein -
CRT37_RS22985 () 21479..22300 + 822 WP_001234426.1 DUF945 domain-containing protein -
CRT37_RS22990 () 22597..23199 - 603 WP_013362798.1 hypothetical protein VF
CRT37_RS22995 () 23520..23903 + 384 WP_001151524.1 relaxosome protein TraM -
CRT37_RS23000 () 24090..24779 + 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
CRT37_RS23005 () 24878..25273 + 396 WP_001309237.1 conjugal transfer relaxosome protein TraY -
CRT37_RS23010 () 25306..25671 + 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
CRT37_RS23015 () 25686..25997 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
CRT37_RS23020 () 26019..26585 + 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
CRT37_RS23025 () 26596..27300 + 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
CRT37_RS23030 () 27300..28727 + 1428 WP_000146685.1 conjugal transfer protein TraB -
CRT37_RS23035 () 28717..29307 + 591 WP_000002787.1 conjugal transfer protein TraP -
CRT37_RS23040 () 29261..29491 + 231 WP_001352845.1 conjugal transfer protein TrbD -
CRT37_RS23045 () 29503..29754 + 252 WP_001038342.1 conjugal transfer protein TrbG -
CRT37_RS23050 () 29751..30266 + 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
CRT37_RS23055 () 30401..30622 + 222 WP_001278689.1 conjugal transfer protein TraR -
CRT37_RS23060 () 30782..33409 + 2628 WP_001064245.1 type IV secretion system protein TraC -
CRT37_RS23065 () 33406..33792 + 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
CRT37_RS23070 () 33789..34421 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
CRT37_RS23075 () 34418..35410 + 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
CRT37_RS23080 () 35419..36057 + 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
CRT37_RS23085 () 36054..37862 + 1809 WP_000821840.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CRT37_RS23090 () 37889..38146 + 258 WP_000864312.1 conjugal transfer protein TrbE -
CRT37_RS23095 () 38139..38882 + 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
CRT37_RS23100 () 38969..40189 + 1221 WP_000343760.1 ISL3 family transposase ISKox3 Transposase
CRT37_RS23105 () 40220..40561 + 342 WP_000556794.1 conjugal transfer protein TrbA -
CRT37_RS23110 () 40542..40877 - 336 WP_000415571.1 hypothetical protein -
CRT37_RS23115 () 40958..41242 + 285 WP_000624105.1 type-F conjugative transfer system pilin chaperone TraQ -
CRT37_RS23120 () 41229..41783 + 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CRT37_RS23125 () 41713..42087 + 375 WP_071788165.1 P-type conjugative transfer protein TrbJ -
CRT37_RS23130 () 42041..42433 + 393 WP_000164675.1 F-type conjugal transfer protein TrbF -
CRT37_RS23135 () 42420..43793 + 1374 WP_021518370.1 conjugal transfer protein TraH -
CRT37_RS23140 () 43790..46615 + 2826 WP_001553826.1 conjugal transfer mating pair stabilization protein TraG -
CRT37_RS23145 () 46612..47121 + 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
CRT37_RS23150 () 47135..47866 + 732 WP_000850424.1 complement resistance protein TraT -
CRT37_RS23155 () 48118..50298 + 2181 WP_013362804.1 type IV conjugative transfer system coupling protein TraD -
CRT37_RS23160 () 50298..55418 + 5121 WP_013362805.1 Multifunctional conjugation protein TraI Relaxase
CRT37_RS23165 () 55438..56184 + 747 WP_023149624.1 conjugal transfer pilus acetylase TraX -
CRT37_RS23170 () 56239..56799 + 561 WP_000139363.1 fertility inhibition protein FinO -
CRT37_RS23175 () 56933..57145 + 213 WP_005012601.1 hypothetical protein -
CRT37_RS24390 () 57446..57535 - 90 Protein_67 IS1 family transposase -
CRT37_RS23190 () 57590..58267 + 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
CRT37_RS23195 () 58267..58614 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
CRT37_RS23200 () 58634..60205 + 1572 WP_023149734.1 IS66 family transposase ISCro1 Transposase
CRT37_RS23205 () 60243..60859 - 617 Protein_71 IS1 family transposase IS1G Transposase
CRT37_RS23210 () 60960..61142 + 183 WP_000968309.1 hypothetical protein -
- () 61281..61342 - 62 NuclAT_2 - Antitoxin Detail
- () 61281..61342 - 62 NuclAT_2 - Antitoxin Detail
- () 61281..61342 - 62 NuclAT_2 - Antitoxin Detail
- () 61281..61342 - 62 NuclAT_2 - Antitoxin Detail
CRT37_RS23220 () 61329..61535 + 207 WP_015387399.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
CRT37_RS23225 () 61819..62076 + 258 WP_000083833.1 replication regulatory protein RepA -
CRT37_RS23235 () 62312..62386 + 75 WP_032336874.1 RepA leader peptide Tap -
CRT37_RS23240 () 62379..62825 + 447 Protein_76 incFII family plasmid replication initiator RepA -
CRT37_RS23245 () 62771..63253 - 483 Protein_77 VENN motif pre-toxin domain-containing protein -
CRT37_RS23250 () 64146..65366 + 1221 WP_000410951.1 arginine deiminase -
CRT37_RS23255 () 65377..66288 + 912 WP_000440183.1 carbamate kinase -
CRT37_RS23260 () 66373..67377 + 1005 WP_000154545.1 Ornithine carbamoyltransferase VF
CRT37_RS23265 () 67425..68828 + 1404 WP_000514417.1 YfcC family protein -
CRT37_RS23270 () 68909..69388 + 480 WP_001496175.1 ArgR family transcriptional regulator -
CRT37_RS23275 () 69452..69793 - 342 Protein_83 transposase -
CRT37_RS23280 () 69745..69966 - 222 WP_000080227.1 IS66 family transposase ISEc43 Transposase
CRT37_RS23285 () 69997..70347 - 351 WP_000624725.1 IS66 family transposase ISEc47 Transposase
CRT37_RS23290 () 70344..70706 - 363 WP_059330006.1 IS66 family transposase ISEc23 Transposase
CRT37_RS23295 () 70815..71512 - 698 Protein_87 IS1 family transposase IS1S Transposase
CRT37_RS23300 () 71545..72123 + 579 WP_032152936.1 DUF2726 domain-containing protein -
CRT37_RS23305 () 72536..72889 - 354 WP_000005489.1 hypothetical protein -
CRT37_RS23310 () 73361..74383 - 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
CRT37_RS23320 () 74788..75045 + 258 WP_000083821.1 replication regulatory protein RepA -
CRT37_RS23330 () 75280..75354 + 75 WP_001365705.1 RepA leader peptide Tap -
CRT37_RS23335 () 75347..76204 + 858 WP_124759836.1 incFII family plasmid replication initiator RepA -
CRT37_RS23350 () 78457..79110 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
CRT37_RS23355 () 79203..79460 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
CRT37_RS23360 () 79393..79794 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
CRT37_RS23365 () 80043..80458 + 416 Protein_98 IS1 family transposase -
CRT37_RS23370 () 80494..81039 - 546 Protein_99 Tn3 family transposase TnpA_Tn3 Transposase
CRT37_RS23375 () 81105..81809 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CRT37_RS24285 () 81922..81987 - 66 Protein_101 EAL domain-containing protein -
CRT37_RS23385 () 82031..82336 - 306 WP_000130000.1 hypothetical protein Relaxase
CRT37_RS23390 () 82347..83552 - 1206 WP_000184001.1 chromate efflux transporter -
CRT37_RS23395 () 83708..83911 - 204 WP_000376616.1 hypothetical protein -
CRT37_RS23405 () 84039..84878 - 840 WP_000259031.1 Dihydropteroate synthase ARG
CRT37_RS23410 () 84872..85219 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
CRT37_RS23415 () 85425..86213 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
CRT37_RS23420 () 86344..86817 - 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
CRT37_RS23425 () 86975..87655 + 681 Protein_109 IS91 family transposase ISAzo26 Transposase
CRT37_RS23430 () 87720..88424 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CRT37_RS23435 () 88568..89122 + 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
CRT37_RS23440 () 89253..90083 + 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
CRT37_RS23445 () 90221..90661 + 441 Protein_113 CatB-related O-acetyltransferase -
CRT37_RS23450 () 90715..91419 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CRT37_RS23455 () 91526..92386 + 861 WP_000557452.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
CRT37_RS23460 () 92399..92941 + 543 WP_002063889.1 AAA family ATPase -
CRT37_RS23465 () 93033..94081 + 1049 Protein_117 IS3 family transposase ISKpn11 Transposase
CRT37_RS23470 () 94135..94839 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CRT37_RS23475 () 94904..97147 - 2244 Protein_119 Tn3 family transposase TnpA_Tn3 Transposase
CRT37_RS23480 () 97161..97493 + 333 WP_001393253.1 WbuC family cupin fold metalloprotein -
CRT37_RS23485 () 97540..98415 - 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
CRT37_RS23490 () 98671..99933 - 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
CRT37_RS23495 () 100139..100333 - 195 Protein_123 Tn3 family transposase TnpA_Tn3 Transposase
CRT37_RS24395 () 100497..100652 + 156 Protein_124 recombinase family protein -
CRT37_RS23505 () 100706..101410 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
CRT37_RS23510 () 101472..101992 - 521 Protein_126 IS1 family transposase -
CRT37_RS24400 () 102192..102305 + 114 Protein_127 IS6 family transposase -
CRT37_RS23525 () 102455..102613 + 159 WP_000449408.1 DsbA family protein -
CRT37_RS23530 () 102603..103109 + 507 WP_000949452.1 protein disulfide oxidoreductase -
CRT37_RS23535 () 103292..104107 + 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
CRT37_RS23545 () 104454..106340 + 1887 WP_000118029.1 FTR1 family iron permease -
CRT37_RS23550 () 106381..106908 + 528 WP_000178050.1 iron transporter -
CRT37_RS23555 () 107012..108391 + 1380 WP_000119836.1 DUF2318 domain-containing protein -
CRT37_RS23560 () 108394..109677 + 1284 WP_000964653.1 ABC transporter permease -
CRT37_RS23565 () 109667..110797 + 1131 WP_000729219.1 ABC transporter permease -
CRT37_RS23570 () 110802..111497 + 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
CRT37_RS23575 () 111484..111969 + 486 WP_001267176.1 TlpA family protein disulfide reductase -
CRT37_RS23580 () 111994..112479 + 486 WP_000874189.1 hypothetical protein -
CRT37_RS23585 () 112601..113233 + 633 Protein_139 histidine-type phosphatase -
CRT37_RS23590 () 113383..113487 - 105 Protein_140 IS5/IS1182 family transposase -
CRT37_RS23595 () 113622..114326 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CRT37_RS23600 () 114351..114725 + 375 WP_024193849.1 IS66 family transposase ISKpn24 Transposase
CRT37_RS23605 () 114774..115719 + 946 Protein_143 IS66 family transposase ISEc8 Transposase
CRT37_RS23615 () 115805..116827 + 1023 WP_000255956.1 IS21 family transposase IS100kyp Transposase
CRT37_RS23620 () 116824..117606 + 783 WP_001317493.1 IS21 family transposase IS100kyp Transposase
CRT37_RS23625 () 117674..118282 + 609 Protein_146 IS66 family transposase ISEc22 Transposase
CRT37_RS23630 () 118345..119136 - 792 WP_000977394.1 DUF4198 domain-containing protein -
CRT37_RS23635 () 119143..121113 - 1971 WP_001496335.1 Hemin receptor VF
CRT37_RS23640 () 121395..121831 + 437 Protein_149 IS3 family transposase IS2 Transposase
CRT37_RS23645 () 122356..122628 + 273 WP_001322642.1 adhesin biosynthesis transcription regulatory family protein -
CRT37_RS23650 () 123074..123249 + 176 Protein_151 IS3 family transposase -
CRT37_RS23655 () 123475..124644 - 1170 WP_001072358.1 hypothetical protein -
CRT37_RS23660 () 125011..125199 + 189 WP_001309252.1 hypothetical protein -
CRT37_RS23665 () 125320..126060 + 741 WP_001066953.1 tyrosine-type recombinase/integrase -
CRT37_RS23670 () 126345..127322 - 978 WP_000361611.1 RepB family plasmid replication initiator protein -
CRT37_RS23680 () 128068..128391 + 324 Protein_156 IS21 family transposase IS21 Transposase
CRT37_RS24405 () 128393..128497 + 105 Protein_157 AAA family ATPase -
CRT37_RS23690 () 128558..129071 + 514 Protein_158 DUF4113 domain-containing protein -
CRT37_RS23695 () 129251..129948 - 698 Protein_159 IS1 family transposase IS1G Transposase
CRT37_RS23705 () 130304..131218 + 915 WP_000949005.1 Putative metal ABC transporter substrate-binding protein Hpf VF
CRT37_RS23710 () 131218..132045 + 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
CRT37_RS23715 () 132042..132899 + 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
CRT37_RS23720 () 132896..133753 + 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
CRT37_RS23730 () 134242..134655 + 414 Protein_164 phosphopyruvate hydratase -
CRT37_RS23740 () 134996..135376 + 381 WP_001318207.1 fluoride efflux transporter CrcB -
CRT37_RS23745 () 135756..136949 - 1194 WP_000095526.1 MFS transporter -
CRT37_RS23750 () 137085..138809 + 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
CRT37_RS23755 () 138810..139757 + 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
CRT37_RS23760 () 139757..141499 + 1743 WP_001015721.1 Aerobactin synthase VF
CRT37_RS23765 () 141496..142773 + 1278 WP_000750130.1 L-lysine N6-monooxygenase VF
CRT37_RS23770 () 142855..145056 + 2202 WP_000973519.1 Ferric aerobactin receptor VF
CRT37_RS23775 () 145582..146268 + 687 Protein_172 IS1 family transposase IS1S Transposase
CRT37_RS23780 () 146522..147544 - 1023 WP_000361402.1 helicase UvrD -
CRT37_RS23785 () 147529..149094 - 1566 WP_001128474.1 AAA family ATPase -
CRT37_RS23790 () 149169..149585 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin -
CRT37_RS23795 () 149582..149812 - 231 WP_001261286.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
CRT37_RS23805 () 150372..150590 + 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA -
CRT37_RS23810 () 150592..150897 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB -
CRT37_RS23815 () 150898..151704 + 807 WP_000016970.1 site-specific integrase -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance