MGE detailed information
MGE type: Conjugative plasmid MGE length: 162357 bp
Accession: NZ_CP019251 Location: 1..162357 Organism: Escherichia coli strain 13KWH46 Replicon: plasmid p13KWH46-1
Accession: NZ_CP019251 Location: 1..162357 Organism: Escherichia coli strain 13KWH46 Replicon: plasmid p13KWH46-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BWI84_RS25270 () | 1..258 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| BWI84_RS25280 () | 490..564 | + | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| BWI84_RS25285 () | 557..1039 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| BWI84_RS25290 () | 1032..1889 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| BWI84_RS29145 () | 2590..2730 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| BWI84_RS25300 () | 2828..3470 | + | 643 | Protein_5 | CPBP family intramembrane metalloprotease | - |
| BWI84_RS25305 () | 3563..3820 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| BWI84_RS25310 () | 4027..5235 | - | 1209 | WP_000198533.1 | IS91 family transposase ISSbo1 | Transposase |
| BWI84_RS25315 () | 5216..5488 | - | 273 | WP_000019163.1 | hypothetical protein | - |
| BWI84_RS25325 () | 5541..5867 | + | 327 | WP_032194589.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| BWI84_RS25340 () | 6116..6813 | + | 698 | Protein_10 | IS1 family transposase IS1R | Transposase |
| BWI84_RS25345 () | 6920..7354 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| BWI84_RS25350 () | 7426..7776 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| BWI84_RS25355 () | 7790..8065 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| BWI84_RS25360 () | 8101..8523 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| BWI84_RS25365 () | 8575..10269 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| BWI84_RS25370 () | 10287..10649 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| BWI84_RS25375 () | 10646..10882 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| BWI84_RS25380 () | 10918..11586 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| BWI84_RS25390 () | 11661..12911 | + | 1251 | Protein_19 | DDE-type integrase/transposase/recombinase | - |
| BWI84_RS25395 () | 12976..13680 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI84_RS25400 () | 13870..14685 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BWI84_RS25405 () | 14836..15540 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI84_RS25410 () | 15601..16437 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| BWI84_RS25415 () | 16437..17240 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| BWI84_RS25420 () | 17301..18116 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| BWI84_RS25430 () | 18424..19275 | - | 852 | WP_000240536.1 | replication protein | - |
| BWI84_RS25435 () | 19262..19981 | - | 720 | Protein_27 | AAA family ATPase | - |
| BWI84_RS25445 () | 20031..20735 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI84_RS25455 () | 20801..20980 | + | 180 | Protein_29 | helix-turn-helix domain-containing protein | - |
| BWI84_RS25460 () | 21163..22023 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| BWI84_RS25465 () | 22172..22849 | + | 678 | Protein_31 | IS4 family transposase IS10R | Transposase |
| BWI84_RS25470 () | 22859..23230 | - | 372 | WP_035689358.1 | Transposon Tn10 TetD protein | VF |
| BWI84_RS25475 () | 23363..23956 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| BWI84_RS25480 () | 24069..25274 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| BWI84_RS25485 () | 25356..25979 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| BWI84_RS25490 () | 25957..26643 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| BWI84_RS25495 () | 26651..27037 | - | 387 | WP_000460653.1 | hypothetical protein | - |
| BWI84_RS25500 () | 27030..27350 | - | 321 | WP_000562367.1 | antibiotic biosynthesis monooxygenase | - |
| BWI84_RS25505 () | 27794..28999 | + | 1206 | WP_000599533.1 | sodium/glutamate symporter | - |
| BWI84_RS25510 () | 29230..29349 | + | 120 | Protein_40 | LysR family transcriptional regulator | - |
| BWI84_RS25515 () | 29365..30573 | - | 1209 | WP_148116933.1 | IS4 family transposase IS10R | Transposase |
| BWI84_RS25525 () | 30734..31393 | + | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| BWI84_RS25530 () | 31594..31971 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| BWI84_RS25535 () | 32038..35004 | - | 2967 | WP_148116990.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| BWI84_RS25540 () | 35007..35567 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| BWI84_RS28910 () | 35693..36043 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| BWI84_RS25550 () | 36246..37259 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| BWI84_RS25555 () | 37417..37890 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| BWI84_RS25560 () | 37964..38668 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| BWI84_RS25570 () | 38770..39249 | + | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| BWI84_RS25575 () | 39319..42471 | - | 3153 | WP_000347934.1 | Efflux pump membrane transporter BepE | VF |
| BWI84_RS25580 () | 42495..43670 | - | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| BWI84_RS25585 () | 43990..44693 | + | 704 | Protein_53 | IS6 family transposase IS26 | Transposase |
| BWI84_RS25590 () | 45028..45420 | + | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| BWI84_RS25595 () | 45740..46126 | - | 387 | WP_063102497.1 | bleomycin binding protein | - |
| BWI84_RS25605 () | 46320..47023 | - | 704 | Protein_56 | IS6 family transposase IS26 | Transposase |
| BWI84_RS25610 () | 47091..48389 | + | 1299 | Protein_57 | Tn3 family transposase TnpA_Tn3 | Transposase |
| BWI84_RS25615 () | 48425..49285 | - | 861 | Protein_58 | IS66 family transposase ISEc8 | Transposase |
| BWI84_RS25620 () | 49335..49682 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| BWI84_RS25625 () | 49679..50059 | - | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| BWI84_RS25630 () | 50135..51115 | - | 981 | WP_063099985.1 | NAD(P)-binding domain-containing protein | - |
| BWI84_RS25635 () | 51112..51381 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| BWI84_RS25640 () | 51383..52160 | - | 778 | Protein_63 | gfo/Idh/MocA family oxidoreductase | - |
| BWI84_RS28915 () | 52321..52557 | + | 237 | WP_001323890.1 | colicin V immunity protein | - |
| BWI84_RS25650 () | 52535..52846 | + | 312 | WP_001259758.1 | colicin V | - |
| BWI84_RS25655 () | 53016..55130 | - | 2115 | WP_001183604.1 | peptidase domain-containing ABC transporter | - |
| BWI84_RS25660 () | 55105..56379 | - | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| BWI84_RS25665 () | 57061..57258 | + | 198 | WP_001324224.1 | toxin-antitoxin system protein | Antitoxin Detail |
| BWI84_RS25670 () | 57255..57437 | + | 183 | WP_000969988.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| BWI84_RS25675 () | 57536..57844 | + | 309 | WP_000377483.1 | hypothetical protein | - |
| BWI84_RS25685 () | 58404..59438 | + | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| BWI84_RS25705 () | 60304..62481 | + | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| BWI84_RS25710 () | 62526..63482 | - | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| BWI84_RS25715 () | 63567..64796 | - | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| BWI84_RS25720 () | 64900..68559 | - | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| BWI84_RS25725 () | 68699..69814 | - | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| BWI84_RS25735 () | 71050..72149 | - | 1100 | Protein_77 | IS481 family transposase ISKpn28 | Transposase |
| BWI84_RS28920 () | 72760..72901 | + | 142 | Protein_78 | lysis system i-spanin subunit Rz | - |
| BWI84_RS25750 () | 72959..73252 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| BWI84_RS25760 () | 73832..74397 | + | 566 | Protein_80 | IS3 family transposase IS2 | Transposase |
| BWI84_RS25770 () | 75638..76366 | + | 729 | Protein_82 | IS3 family transposase IS2 | Transposase |
| BWI84_RS25780 () | 77608..78801 | + | 1194 | WP_000450494.1 | GTP-binding protein | - |
| BWI84_RS25785 () | 78979..79128 | + | 150 | Protein_84 | IS3 family transposase IS2 | Transposase |
| BWI84_RS25790 () | 79438..80827 | + | 1390 | Protein_85 | ISNCY family transposase ISKpn21 | Transposase |
| BWI84_RS25800 () | 81062..82003 | + | 942 | WP_000974762.1 | hypothetical protein | - |
| BWI84_RS25805 () | 82132..82326 | - | 195 | Protein_87 | IS200-IS605 family transposase IS200C | Transposase |
| BWI84_RS25815 () | 82800..84170 | - | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| BWI84_RS25820 () | 84174..86113 | - | 1940 | Protein_89 | Macrolide export ATP-binding/permease protein MacB | VF |
| BWI84_RS25825 () | 86110..87297 | - | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| BWI84_RS25830 () | 88278..88596 | + | 319 | Protein_91 | IS3 family transposase ISLad1 | Transposase |
| BWI84_RS25835 () | 88749..89949 | - | 1201 | Protein_92 | IS3 family transposase IS629 | Transposase |
| BWI84_RS25840 () | 90133..90291 | + | 159 | WP_001324039.1 | integrase core domain-containing protein | - |
| BWI84_RS25855 () | 91564..92516 | + | 953 | Protein_94 | Protease 7 | VF |
| BWI84_RS25865 () | 92949..94058 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| BWI84_RS25870 () | 94127..95029 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| BWI84_RS25875 () | 95403..95591 | + | 189 | WP_001324033.1 | hypothetical protein | - |
| BWI84_RS25880 () | 95712..96452 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| BWI84_RS25885 () | 96737..97714 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| BWI84_RS25895 () | 98460..98783 | + | 324 | Protein_100 | IS21 family transposase IS21 | Transposase |
| BWI84_RS29150 () | 98785..98889 | + | 105 | Protein_101 | AAA family ATPase | - |
| BWI84_RS25905 () | 98950..99463 | + | 514 | Protein_102 | DUF4113 domain-containing protein | - |
| BWI84_RS25910 () | 99643..100339 | - | 697 | Protein_103 | IS1 family transposase IS1S | Transposase |
| BWI84_RS25925 () | 100695..101609 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| BWI84_RS25930 () | 101609..102436 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| BWI84_RS25935 () | 102433..103290 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| BWI84_RS25940 () | 103287..104144 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| BWI84_RS25945 () | 104378..104635 | - | 258 | Protein_108 | Tn3 family transposase | - |
| BWI84_RS25950 () | 104633..105046 | + | 414 | Protein_109 | phosphopyruvate hydratase | - |
| BWI84_RS25960 () | 105387..105767 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| BWI84_RS25965 () | 106146..107339 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| BWI84_RS25970 () | 107475..109199 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| BWI84_RS25975 () | 109200..110147 | + | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| BWI84_RS25980 () | 110147..111889 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| BWI84_RS25985 () | 111886..113163 | + | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| BWI84_RS25990 () | 113245..115446 | + | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| BWI84_RS26005 () | 115931..116628 | + | 698 | Protein_117 | IS1 family transposase IS1S | Transposase |
| BWI84_RS26010 () | 116928..118094 | + | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| BWI84_RS26015 () | 118094..119065 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| BWI84_RS29155 () | 120204..120410 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| BWI84_RS26030 () | 120436..120975 | + | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| BWI84_RS26035 () | 121043..121276 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| BWI84_RS26040 () | 121304..121501 | + | 198 | Protein_123 | hypothetical protein | - |
| BWI84_RS26045 () | 121556..121990 | + | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| BWI84_RS26050 () | 121987..122706 | + | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| BWI84_RS28930 () | 122718..122906 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 122718..122942 | + | 225 | NuclAT_0 | - | - |
| - () | 122718..122942 | + | 225 | NuclAT_0 | - | - |
| - () | 122718..122942 | + | 225 | NuclAT_0 | - | - |
| - () | 122718..122942 | + | 225 | NuclAT_0 | - | - |
| BWI84_RS26055 () | 122986..123144 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| BWI84_RS26070 () | 124065..124352 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| BWI84_RS26075 () | 124470..125291 | + | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| BWI84_RS26080 () | 125588..126190 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| BWI84_RS26085 () | 126511..126894 | + | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| BWI84_RS26090 () | 127081..127770 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| BWI84_RS26095 () | 127869..128264 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| BWI84_RS26100 () | 128297..128662 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| BWI84_RS26105 () | 128677..128988 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| BWI84_RS26110 () | 129010..129576 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| BWI84_RS26115 () | 129587..130291 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| BWI84_RS26120 () | 130291..131718 | + | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| BWI84_RS26125 () | 131708..132298 | + | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| BWI84_RS26130 () | 132252..132605 | + | 354 | WP_071594066.1 | conjugal transfer protein TrbD | - |
| BWI84_RS26135 () | 132598..132849 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| BWI84_RS26140 () | 132846..133361 | + | 516 | WP_015059130.1 | type IV conjugative transfer system lipoprotein TraV | - |
| BWI84_RS26145 () | 133496..133717 | + | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| BWI84_RS26150 () | 133710..134186 | + | 477 | WP_015059129.1 | hypothetical protein | - |
| BWI84_RS26155 () | 134266..134480 | + | 215 | Protein_145 | hypothetical protein | - |
| BWI84_RS28935 () | 134508..134870 | + | 363 | WP_000836675.1 | hypothetical protein | - |
| BWI84_RS26165 () | 134996..137626 | + | 2631 | WP_000069764.1 | type IV secretion system protein TraC | - |
| BWI84_RS26170 () | 137623..138009 | + | 387 | WP_000214092.1 | type-F conjugative transfer system protein TrbI | - |
| BWI84_RS26175 () | 138006..138638 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| BWI84_RS26180 () | 138635..139627 | + | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| BWI84_RS26185 () | 139636..140274 | + | 639 | WP_000777692.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| BWI84_RS26190 () | 140271..142079 | + | 1809 | WP_000821821.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| BWI84_RS26195 () | 142106..142363 | + | 258 | WP_000864352.1 | conjugal transfer protein TrbE | - |
| BWI84_RS26200 () | 142356..143099 | + | 744 | WP_001430248.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| BWI84_RS26205 () | 143115..143462 | + | 348 | WP_001287891.1 | conjugal transfer protein TrbA | - |
| BWI84_RS26210 () | 143581..143865 | + | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| BWI84_RS26215 () | 143852..144397 | + | 546 | WP_000059821.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| BWI84_RS26220 () | 144327..144689 | + | 363 | WP_010379880.1 | P-type conjugative transfer protein TrbJ | - |
| BWI84_RS26225 () | 144689..146061 | + | 1373 | Protein_159 | conjugal transfer protein TraH | - |
| BWI84_RS26230 () | 146058..148880 | + | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| BWI84_RS26235 () | 148896..149393 | + | 498 | WP_000605857.1 | entry exclusion protein | - |
| BWI84_RS26240 () | 149425..150156 | + | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| BWI84_RS26245 () | 150409..152562 | + | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| BWI84_RS26250 () | 152571..152969 | - | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| BWI84_RS26255 () | 152969..153196 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| BWI84_RS26260 () | 153278..158548 | + | 5271 | WP_148116991.1 | Multifunctional conjugation protein TraI | Relaxase |
| BWI84_RS26265 () | 158568..159314 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| BWI84_RS26270 () | 159373..160233 | + | 861 | WP_000704514.1 | putative protein YcjY | VF |
| BWI84_RS26275 () | 160336..160896 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| BWI84_RS26280 () | 161032..161244 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| BWI84_RS29160 () | 161490..161564 | + | 75 | Protein_171 | endonuclease | - |
| - () | 161820..161881 | - | 62 | NuclAT_1 | - | - |
| - () | 161820..161881 | - | 62 | NuclAT_1 | - | - |
| - () | 161820..161881 | - | 62 | NuclAT_1 | - | - |
| - () | 161820..161881 | - | 62 | NuclAT_1 | - | - |
| BWI84_RS26290 () | 161868..162074 | + | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|