MGE detailed information
MGE type: Conjugative plasmid MGE length: 149732 bp
Accession: NZ_CP014489 Location: 1..149732 Organism: Escherichia coli strain G749 Replicon: plasmid pG749_1
Accession: NZ_CP014489 Location: 1..149732 Organism: Escherichia coli strain G749 Replicon: plasmid pG749_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AVR74_RS24270 () | 295..555 | - | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| AVR74_RS24275 () | 795..1385 | - | 591 | WP_000766816.1 | DUF2726 domain-containing protein | - |
| AVR74_RS24280 () | 1424..1633 | - | 210 | WP_001514235.1 | hemolysin expression modulator Hha | - |
| AVR74_RS24290 () | 1764..2461 | + | 698 | Protein_5 | IS1 family transposase IS1S | Transposase |
| AVR74_RS24295 () | 2477..2917 | - | 441 | Protein_6 | thermonuclease family protein | - |
| AVR74_RS24300 () | 3162..3374 | - | 213 | WP_001371875.1 | ANR family transcriptional regulator | - |
| AVR74_RS24305 () | 3507..4067 | - | 561 | WP_000840464.1 | fertility inhibition protein FinO | - |
| AVR74_RS24310 () | 4170..5030 | - | 861 | WP_000704522.1 | hypothetical protein | VF |
| AVR74_RS24315 () | 5089..5835 | - | 747 | WP_000205766.1 | conjugal transfer pilus acetylase TraX | - |
| AVR74_RS29315 () | 5855..11123 | - | 5269 | Protein_11 | Multifunctional conjugation protein TraI | Relaxase |
| AVR74_RS24325 () | 11123..13276 | - | 2154 | WP_001369365.1 | type IV conjugative transfer system coupling protein TraD | - |
| AVR74_RS24330 () | 13529..14260 | - | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| AVR74_RS24335 () | 14274..14783 | - | 510 | WP_000628099.1 | conjugal transfer entry exclusion protein TraS | - |
| AVR74_RS24340 () | 14780..17605 | - | 2826 | WP_001007045.1 | conjugal transfer mating pair stabilization protein TraG | - |
| AVR74_RS24345 () | 17602..18975 | - | 1374 | WP_001137358.1 | conjugal transfer protein TraH | - |
| AVR74_RS24350 () | 18975..19337 | - | 363 | WP_010379880.1 | P-type conjugative transfer protein TrbJ | - |
| AVR74_RS24355 () | 19267..19812 | - | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| AVR74_RS24360 () | 19799..20083 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| AVR74_RS24365 () | 20202..20549 | - | 348 | WP_001287677.1 | conjugal transfer protein TrbA | - |
| AVR74_RS24370 () | 20565..21308 | - | 744 | WP_001514239.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| AVR74_RS24375 () | 21301..21558 | - | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| AVR74_RS24380 () | 21585..23393 | - | 1809 | WP_000821846.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| AVR74_RS24385 () | 23390..24028 | - | 639 | WP_000777693.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| AVR74_RS24390 () | 24037..25029 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| AVR74_RS24395 () | 25026..25658 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| AVR74_RS24400 () | 25655..26041 | - | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| AVR74_RS24405 () | 26038..28665 | - | 2628 | WP_001064252.1 | type IV secretion system protein TraC | - |
| AVR74_RS27645 () | 28825..29046 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| AVR74_RS24410 () | 29181..29696 | - | 516 | WP_000809841.1 | type IV conjugative transfer system lipoprotein TraV | - |
| AVR74_RS24415 () | 29693..29944 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| AVR74_RS24420 () | 29956..30186 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| AVR74_RS24425 () | 30140..30730 | - | 591 | WP_000002796.1 | conjugal transfer protein TraP | - |
| AVR74_RS24430 () | 30720..32147 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| AVR74_RS24435 () | 32147..32851 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| AVR74_RS24440 () | 32862..33428 | - | 567 | WP_000399785.1 | type IV conjugative transfer system protein TraE | - |
| AVR74_RS24445 () | 33450..33761 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| AVR74_RS24450 () | 33776..34141 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| AVR74_RS24455 () | 34174..34569 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| AVR74_RS24460 () | 34668..35357 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| AVR74_RS24465 () | 35544..35927 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| AVR74_RS24470 () | 36261..36851 | + | 591 | Protein_42 | hypothetical protein | VF |
| AVR74_RS24475 () | 37147..37968 | - | 822 | WP_001234468.1 | DUF945 domain-containing protein | - |
| AVR74_RS24480 () | 38087..38374 | - | 288 | WP_000107520.1 | hypothetical protein | - |
| AVR74_RS29320 () | 38675..38972 | + | 298 | Protein_45 | hypothetical protein | - |
| AVR74_RS24495 () | 39273..39434 | - | 162 | WP_001332444.1 | type I toxin-antitoxin system Hok family toxin | - |
| - () | 39487..39698 | - | 212 | NuclAT_0 | - | - |
| - () | 39487..39698 | - | 212 | NuclAT_0 | - | - |
| - () | 39487..39698 | - | 212 | NuclAT_0 | - | - |
| - () | 39487..39698 | - | 212 | NuclAT_0 | - | - |
| AVR74_RS24505 () | 39710..40429 | - | 720 | WP_000994098.1 | plasmid SOS inhibition protein A | - |
| AVR74_RS24510 () | 40426..40860 | - | 435 | WP_000845922.1 | conjugation system SOS inhibitor PsiB | - |
| AVR74_RS24515 () | 40915..42873 | - | 1959 | WP_000117202.1 | ParB/RepB/Spo0J family partition protein | - |
| AVR74_RS24520 () | 42937..43170 | - | 234 | WP_000005988.1 | DUF905 family protein | - |
| AVR74_RS24525 () | 43133..43765 | - | 633 | WP_000290818.1 | single-stranded DNA-binding protein | - |
| AVR74_RS24535 () | 44066..44485 | + | 420 | WP_015056142.1 | hypothetical protein | - |
| AVR74_RS24540 () | 44571..45134 | - | 564 | WP_001332335.1 | class I SAM-dependent methyltransferase | - |
| AVR74_RS24545 () | 45182..46543 | - | 1362 | WP_000170680.1 | DUF3560 domain-containing protein | - |
| AVR74_RS24550 () | 46595..46825 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| AVR74_RS29325 () | 47503..47831 | + | 329 | Protein_56 | pilus assembly protein | - |
| AVR74_RS24560 () | 47819..48001 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| AVR74_RS24565 () | 48001..48462 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| AVR74_RS24570 () | 48462..48764 | - | 303 | WP_072256028.1 | antirestriction protein | - |
| AVR74_RS24575 () | 49289..50260 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| AVR74_RS24580 () | 50521..50733 | - | 213 | WP_000092896.1 | hypothetical protein | - |
| AVR74_RS24585 () | 50746..51320 | - | 575 | Protein_62 | hypothetical protein | - |
| AVR74_RS29330 () | 51389..51727 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| AVR74_RS24595 () | 52367..53338 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| AVR74_RS24600 () | 53338..54504 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| AVR74_RS24605 () | 54804..55501 | - | 698 | Protein_66 | IS1 family transposase IS1S | Transposase |
| AVR74_RS24610 () | 56026..58227 | - | 2202 | WP_000973517.1 | Ferric aerobactin receptor | VF |
| AVR74_RS24615 () | 58309..59586 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| AVR74_RS24620 () | 59583..61325 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| AVR74_RS24625 () | 61325..62272 | - | 948 | WP_000011907.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| AVR74_RS24630 () | 62273..63997 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| AVR74_RS24635 () | 64133..65326 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| AVR74_RS24640 () | 65706..66086 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| AVR74_RS24650 () | 66427..66840 | - | 414 | Protein_74 | phosphopyruvate hydratase | - |
| AVR74_RS28390 () | 66838..67095 | + | 258 | Protein_75 | Tn3 family transposase | - |
| AVR74_RS24655 () | 67329..68186 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| AVR74_RS24660 () | 68183..69041 | - | 859 | Protein_77 | iron/manganese ABC transporter permease subunit SitC | - |
| AVR74_RS24665 () | 69038..69865 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| AVR74_RS24670 () | 69865..70779 | - | 915 | WP_001514243.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| AVR74_RS24675 () | 71135..71832 | + | 698 | Protein_80 | IS1 family transposase IS1S | Transposase |
| AVR74_RS24680 () | 72012..72525 | - | 514 | Protein_81 | DUF4113 domain-containing protein | - |
| AVR74_RS29335 () | 72586..72690 | - | 105 | Protein_82 | AAA family ATPase | - |
| AVR74_RS24685 () | 72692..73015 | - | 324 | Protein_83 | IS21 family transposase IS21 | Transposase |
| AVR74_RS24700 () | 73761..74738 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| AVR74_RS24705 () | 75023..75763 | - | 741 | WP_001514245.1 | tyrosine-type recombinase/integrase | - |
| AVR74_RS24710 () | 75884..76072 | - | 189 | WP_001332052.1 | hypothetical protein | - |
| AVR74_RS24715 () | 76446..77348 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| AVR74_RS24720 () | 77417..78526 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| AVR74_RS24730 () | 78959..79912 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| AVR74_RS27705 () | 81185..81343 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| AVR74_RS24750 () | 81527..82740 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| AVR74_RS24755 () | 82888..83213 | - | 326 | Protein_92 | IS3 family transposase ISLad1 | Transposase |
| AVR74_RS24760 () | 84194..85381 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| AVR74_RS24765 () | 85378..87318 | + | 1941 | WP_000733252.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| AVR74_RS24770 () | 87322..88692 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| AVR74_RS24775 () | 89166..89360 | + | 195 | Protein_96 | IS200-IS605 family transposase IS200C | Transposase |
| AVR74_RS24780 () | 89489..90430 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| AVR74_RS27720 () | 90665..92054 | - | 1390 | Protein_98 | ISNCY family transposase ISKpn21 | Transposase |
| AVR74_RS28890 () | 92364..92513 | - | 150 | Protein_99 | IS3 family transposase IS2 | Transposase |
| AVR74_RS24805 () | 92691..93884 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| AVR74_RS24825 () | 96963..97256 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| AVR74_RS24830 () | 97314..97513 | - | 200 | Protein_103 | lysis protein | - |
| AVR74_RS28410 () | 98067..99166 | + | 1100 | Protein_104 | IS481 family transposase ISKpn28 | Transposase |
| AVR74_RS24850 () | 100402..101517 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| AVR74_RS24855 () | 101657..105316 | + | 3660 | WP_001442133.1 | Multidrug efflux ATP-binding/permease protein | VF |
| AVR74_RS24860 () | 105420..106649 | + | 1230 | WP_000933672.1 | Enterochelin esterase | VF |
| AVR74_RS24865 () | 106734..107690 | + | 957 | WP_000271277.1 | Ferri-bacillibactin esterase BesA | VF |
| AVR74_RS24870 () | 107735..109912 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| AVR74_RS24880 () | 110767..111801 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| AVR74_RS24885 () | 112361..112669 | - | 309 | WP_000377483.1 | hypothetical protein | - |
| AVR74_RS24890 () | 112768..112950 | - | 183 | WP_001514250.1 | hypothetical protein | Toxin Detail |
| AVR74_RS24895 () | 112947..113144 | - | 198 | WP_001324224.1 | toxin-antitoxin system protein | Antitoxin Detail |
| AVR74_RS24900 () | 113826..115100 | + | 1275 | WP_000489608.1 | HlyD family secretion protein | - |
| AVR74_RS24905 () | 115075..117189 | + | 2115 | WP_001183604.1 | peptidase domain-containing ABC transporter | - |
| AVR74_RS24910 () | 117359..117670 | - | 312 | WP_001259758.1 | colicin V | - |
| AVR74_RS29120 () | 117648..117884 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| AVR74_RS27775 () | 118045..118822 | + | 778 | Protein_118 | Gfo/Idh/MocA family oxidoreductase | - |
| AVR74_RS24930 () | 118824..119093 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| AVR74_RS24935 () | 119090..119356 | + | 267 | WP_001017350.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| AVR74_RS24940 () | 119412..119864 | - | 453 | WP_000670963.1 | N-acetyltransferase | - |
| AVR74_RS24945 () | 120157..120417 | + | 261 | WP_000343091.1 | hypothetical protein | - |
| AVR74_RS24950 () | 120414..121004 | + | 591 | WP_001518980.1 | hypothetical protein | - |
| AVR74_RS24955 () | 121024..121281 | - | 258 | WP_000142431.1 | hypothetical protein | - |
| AVR74_RS24960 () | 121410..121745 | + | 336 | WP_001080729.1 | colicin 1A immunity protein | - |
| AVR74_RS24965 () | 121767..123647 | - | 1881 | WP_001283335.1 | colicin | - |
| AVR74_RS24970 () | 123833..124680 | - | 848 | Protein_127 | 3'-5' exonuclease | - |
| AVR74_RS24975 () | 124726..125007 | - | 282 | WP_000969996.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| AVR74_RS24980 () | 125004..125273 | - | 270 | WP_000079941.1 | hypothetical protein | Antitoxin Detail |
| AVR74_RS24985 () | 125917..128883 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| AVR74_RS24990 () | 128887..129447 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| AVR74_RS29135 () | 129623..129973 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| AVR74_RS25005 () | 130176..131189 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| AVR74_RS25010 () | 131345..131818 | + | 474 | WP_001317507.1 | Dihydrofolate reductase type 1 | ARG |
| AVR74_RS25015 () | 131970..132674 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| AVR74_RS25020 () | 132738..133076 | + | 339 | Protein_136 | Tn3 family transposase TnpR_Tn3 | Transposase |
| AVR74_RS25025 () | 133259..134119 | + | 861 | WP_061158039.1 | Beta-lactamase TEM | ARG |
| AVR74_RS27805 () | 134266..134547 | + | 282 | Protein_138 | transposase zinc-binding domain-containing protein | - |
| AVR74_RS25030 () | 134717..135421 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| AVR74_RS25035 () | 135471..136190 | + | 720 | Protein_140 | AAA family ATPase | - |
| AVR74_RS25040 () | 136177..137147 | + | 971 | Protein_141 | replication protein C | - |
| AVR74_RS25045 () | 137338..138153 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| AVR74_RS25050 () | 138214..139017 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| AVR74_RS25055 () | 139017..139853 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| AVR74_RS25060 () | 139914..140618 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| AVR74_RS25065 () | 140769..141584 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| AVR74_RS25070 () | 141774..142478 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| AVR74_RS25075 () | 142543..143793 | - | 1251 | Protein_148 | transposase | - |
| AVR74_RS25080 () | 143868..144536 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| AVR74_RS25085 () | 144572..144808 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| AVR74_RS25090 () | 144805..145167 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| AVR74_RS25095 () | 145185..146879 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| AVR74_RS25100 () | 146931..147353 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| AVR74_RS25105 () | 147389..147664 | - | 276 | WP_061158040.1 | mercury resistance system periplasmic binding protein MerP | - |
| AVR74_RS25110 () | 147678..148028 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| AVR74_RS25115 () | 148100..148534 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|