NZ_CP0129591942964..2134107

MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 191144 bp
Accession: NZ_CP012959        Location: 1942964..2134107         Organism: Aggregatibacter actinomycetemcomitans strain 624       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACT75_RS09510 () 1938127..1938816 + 690 WP_005545584.1 protein TolQ -
ACT75_RS09515 () 1938902..1939324 + 423 WP_005542289.1 colicin uptake protein TolR -
ACT75_RS09520 () 1939341..1940489 + 1149 WP_005549166.1 cell envelope integrity protein TolA -
ACT75_RS09525 () 1940524..1941804 + 1281 WP_005544509.1 Tol-Pal system protein TolB -
ACT75_RS09530 () 1941819..1942286 + 468 WP_005544510.1 peptidoglycan-associated lipoprotein Pal -
ACT75_RS09550 () 1942991..1943512 + 522 WP_005562086.1 hypothetical protein VF
ACT75_RS09555 () 1943499..1944242 + 744 WP_005549806.1 type II secretion system protein J -
ACT75_RS09560 () 1944239..1944934 + 696 WP_005537951.1 DUF2572 family protein -
ACT75_RS09565 () 1944909..1945211 + 303 WP_005554585.1 DUF5374 domain-containing protein -
ACT75_RS09570 () 1945257..1948646 + 3390 WP_005537947.1 exodeoxyribonuclease V subunit gamma -
ACT75_RS09575 () 1948648..1949091 - 444 WP_005537944.1 Ribosomal-protein-alanine acetyltransferase VF
ACT75_RS09580 () 1949101..1949538 - 438 WP_005549811.1 DNA polymerase III subunit psi -
ACT75_RS09585 () 1949606..1950610 + 1005 WP_005537939.1 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC -
ACT75_RS12145 () 1950697..1950989 + 293 Protein_1890 PTS transporter subunit EIIB -
ACT75_RS09595 () 1951226..1951768 + 543 WP_005537932.1 hypothetical protein -
ACT75_RS09600 () 1951903..1953165 + 1263 WP_005537928.1 serine hydroxymethyltransferase -
ACT75_RS09605 () 1953482..1953934 + 453 WP_061866587.1 serine hydroxymethyltransferase -
ACT75_RS09610 () 1954272..1954778 + 507 WP_005545611.1 Leukotoxin-activating lysine-acyltransferase LtxC VF
ACT75_RS09615 () 1954791..1957958 + 3168 WP_005537925.1 Leukotoxin VF
ACT75_RS09620 () 1958027..1960150 + 2124 WP_005537924.1 Leukotoxin export ATP-binding protein LtxB VF
ACT75_RS09625 () 1960165..1961598 + 1434 WP_005545615.1 Leukotoxin export protein LtxD VF
ACT75_RS09630 () 1962009..1963889 + 1881 WP_005537917.1 PTS mannitol transporter subunit IICBA -
ACT75_RS09635 () 1963967..1965115 + 1149 WP_005537916.1 mannitol-1-phosphate 5-dehydrogenase -
ACT75_RS09640 () 1965193..1965705 + 513 WP_005537910.1 MltR family transcriptional regulator -
ACT75_RS09645 () 1965809..1966819 - 1011 WP_005537901.1 inositol 2-dehydrogenase -
ACT75_RS09650 () 1966822..1967718 - 897 WP_005537898.1 myo-inosose-2 dehydratase -
ACT75_RS09655 () 1967773..1969719 - 1947 WP_005595325.1 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) -
ACT75_RS09660 () 1970030..1971940 + 1911 WP_005537893.1 5-dehydro-2-deoxygluconokinase -
ACT75_RS09665 () 1971977..1972816 - 840 WP_005537890.1 MurR/RpiR family transcriptional regulator -
ACT75_RS09670 () 1973197..1973385 + 189 WP_005537883.1 hypothetical protein -
ACT75_RS12580 () 1973508..1974638 + 1131 WP_014702342.1 hypothetical protein -
ACT75_RS09680 () 1974675..1975325 + 651 WP_061866588.1 hypothetical protein -
ACT75_RS09685 () 1975500..1975682 + 183 WP_005550326.1 hypothetical protein -
ACT75_RS09690 () 1975958..1976533 + 576 WP_005553102.1 hypothetical protein -
ACT75_RS09695 () 1977101..1977370 + 270 WP_005540356.1 PTS sugar transporter subunit IIB -
ACT75_RS09700 () 1977387..1978742 + 1356 WP_005540354.1 PTS ascorbate transporter subunit IIC -
ACT75_RS09705 () 1978752..1979576 + 825 WP_005540352.1 transketolase -
ACT75_RS09710 () 1979566..1980510 + 945 WP_005540351.1 transketolase family protein -
ACT75_RS09715 () 1980677..1981627 - 951 WP_005549138.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase -
ACT75_RS09720 () 1981690..1982196 + 507 WP_005540347.1 endonuclease SmrB -
ACT75_RS09725 () 1982193..1984334 - 2142 WP_005540345.1 TIGR01666 family membrane protein -
ACT75_RS09730 () 1984343..1984816 - 474 WP_005540343.1 YccF domain-containing protein -
ACT75_RS09735 () 1984816..1985274 - 459 WP_005540341.1 methylglyoxal synthase -
ACT75_RS09740 () 1985337..1986017 - 681 WP_005549145.1 DUF2057 domain-containing protein -
ACT75_RS09745 () 1986162..1986434 + 273 WP_005540337.1 acylphosphatase -
ACT75_RS09750 () 1986409..1987257 - 849 WP_005540335.1 Manganese transport system membrane protein MntB VF
ACT75_RS09755 () 1987254..1988111 - 858 WP_005540332.1 iron ABC transporter permease subunit AfeC -
ACT75_RS09760 () 1988111..1989001 - 891 WP_005540330.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
ACT75_RS09765 () 1989001..1989882 - 882 WP_005540327.1 Putative metal ABC transporter substrate-binding protein Hpf VF
ACT75_RS09770 () 1989980..1990309 - 330 WP_014702540.1 TusE/DsrC/DsvC family sulfur relay protein -
ACT75_RS09775 () 1990395..1991057 - 663 WP_005540319.1 BAX inhibitor protein -
ACT75_RS09780 () 1991373..1991807 + 435 WP_005540317.1 CRISPR-associated endonuclease Cas3'' -
ACT75_RS09785 () 1991838..1993623 + 1786 Protein_1929 CRISPR-associated helicase Cas3' -
ACT75_RS09790 () 1993760..1996636 + 2877 WP_005540313.1 DEAD/DEAH box helicase -
ACT75_RS09795 () 1996666..1997259 + 594 WP_061866589.1 hypothetical protein -
ACT75_RS09800 () 1997243..1998184 + 942 WP_005540309.1 DUF4868 domain-containing protein -
ACT75_RS09805 () 1998198..1999934 + 1737 WP_005540307.1 site-specific DNA-methyltransferase -
ACT75_RS09810 () 2000061..2001095 + 1035 WP_005540305.1 virulence RhuM family protein -
ACT75_RS09815 () 2001092..2003809 + 2718 WP_005540302.1 DEAD/DEAH box helicase family protein -
ACT75_RS09820 () 2003924..2004598 + 675 WP_005540300.1 type I-C CRISPR-associated protein Cas5 -
ACT75_RS09825 () 2004595..2006372 + 1778 Protein_1937 type I-C CRISPR-associated protein Cas8c/Csd1 -
ACT75_RS09835 () 2006385..2007251 + 867 WP_005540292.1 type I-C CRISPR-associated protein Cas7/Csd2 -
ACT75_RS09840 () 2007396..2008046 + 651 WP_005540290.1 CRISPR-associated protein Cas4 -
ACT75_RS09845 () 2008073..2008816 + 744 WP_005540287.1 hypothetical protein -
ACT75_RS12585 () 2009143..2009295 + 153 Protein_1941 CRISPR-associated endonuclease Cas2 -
ACT75_RS09850 () 2010252..2010632 + 381 WP_005540283.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
ACT75_RS09855 () 2010654..2011658 + 1005 WP_005540280.1 thiamine ABC transporter substrate binding subunit -
ACT75_RS09860 () 2011667..2013295 + 1629 WP_005540278.1 thiamine/thiamine pyrophosphate ABC transporter permease ThiP -
ACT75_RS09865 () 2013279..2013926 + 648 WP_005540276.1 Thiamine import ATP-binding protein ThiQ VF
ACT75_RS09870 () 2013972..2014976 + 1005 WP_005540274.1 Biotin synthase VF
ACT75_RS09875 () 2015692..2016171 + 480 WP_005540269.1 leucine-responsive transcriptional regulator Lrp -
ACT75_RS09880 () 2016175..2018919 + 2745 WP_005595076.1 DNA translocase FtsK -
ACT75_RS09885 () 2019012..2019629 + 618 WP_005540265.1 outer membrane lipoprotein chaperone LolA -
ACT75_RS09890 () 2019642..2020982 + 1341 WP_005540264.1 replication-associated recombination protein A -
ACT75_RS09895 () 2021479..2023146 - 1668 WP_005540262.1 anaerobic C4-dicarboxylate transporter -
ACT75_RS09900 () 2023453..2024769 + 1317 WP_005540260.1 serine--tRNA ligase -
ACT75_RS09905 () 2024849..2025745 - 897 WP_005549823.1 cytidine deaminase -
ACT75_RS09910 () 2025869..2026966 - 1098 WP_005549825.1 extracellular solute-binding protein -
ACT75_RS09915 () 2027097..2027870 - 774 WP_005542482.1 spermidine/putrescine ABC transporter permease PotC -
ACT75_RS09920 () 2027870..2028730 - 861 WP_005542483.1 spermidine/putrescine ABC transporter permease PotB -
ACT75_RS09925 () 2028714..2029832 - 1119 WP_005542484.1 Spermidine/putrescine import ATP-binding protein PotA VF
ACT75_RS09930 () 2030096..2031340 + 1245 WP_005542485.1 peptidase T -
ACT75_RS09935 () 2031415..2034072 - 2658 WP_005542486.1 hypothetical protein VF
ACT75_RS09940 () 2034035..2035318 - 1284 WP_005542487.1 paraquat-inducible protein A -
ACT75_RS09945 () 2035521..2036147 + 627 WP_005542488.1 RNA chaperone ProQ -
ACT75_RS09950 () 2036221..2038278 + 2058 WP_005542489.1 carboxy terminal-processing peptidase -
ACT75_RS09955 () 2038356..2039864 + 1509 WP_005542490.1 L,D-transpeptidase family protein -
ACT75_RS09960 () 2039929..2040489 + 561 WP_005542491.1 YcbK family protein -
ACT75_RS09965 () 2040566..2041204 + 639 WP_005542492.1 MBL fold metallo-hydrolase -
ACT75_RS09970 () 2041483..2044290 + 2808 WP_044116053.1 2-oxoglutarate dehydrogenase E1 component -
ACT75_RS09975 () 2044416..2045639 + 1224 WP_005542495.1 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase -
ACT75_RS09980 () 2045825..2046994 + 1170 WP_005542496.1 ADP-forming succinate--CoA ligase subunit beta -
ACT75_RS09985 () 2047005..2047877 + 873 WP_005542497.1 succinate--CoA ligase subunit alpha -
ACT75_RS12880 () 2047910..2049202 + 1293 WP_014702551.1 hypothetical protein -
ACT75_RS09995 () 2049204..2049548 + 345 WP_005544611.1 hypothetical protein -
ACT75_RS10000 () 2049711..2050034 + 324 WP_005544613.1 hypothetical protein -
ACT75_RS10005 () 2050244..2052397 - 2154 WP_079254144.1 formate dehydrogenase subunit alpha -
ACT75_RS10015 () 2052599..2053792 - 1194 WP_005542183.1 Fic family protein -
ACT75_RS10020 () 2053920..2054381 - 462 WP_005542184.1 hydrogenase maturation peptidase HycI -
ACT75_RS10025 () 2054371..2054775 - 405 WP_005542185.1 formate hydrogenlyase maturation HycH family protein -
ACT75_RS10030 () 2054857..2055633 - 777 WP_005542186.1 NADH-quinone oxidoreductase subunit B family protein -
ACT75_RS10035 () 2055630..2056277 - 648 WP_005542187.1 4Fe-4S dicluster domain-containing protein -
ACT75_RS10040 () 2056291..2058021 - 1731 WP_005542188.1 hydrogenase large subunit -
ACT75_RS10045 () 2058041..2059579 - 1539 WP_005549755.1 hydrogenase 4 subunit F -
ACT75_RS10050 () 2059584..2060222 - 639 WP_005542193.1 hydrogenase 4 membrane subunit -
ACT75_RS10055 () 2060233..2061678 - 1446 WP_005542195.1 hydrogenase 4 subunit D -
ACT75_RS10060 () 2061691..2062653 - 963 WP_005542197.1 respiratory chain complex I subunit 1 family protein -
ACT75_RS10065 () 2062664..2064685 - 2022 WP_005542199.1 hydrogenase 4 subunit B -
ACT75_RS10070 () 2064719..2065318 - 600 WP_005549758.1 4Fe-4S dicluster domain-containing protein -
ACT75_RS10075 () 2065611..2067896 + 2286 WP_005542203.1 carbamoyltransferase HypF -
ACT75_RS10080 () 2068517..2069230 - 714 WP_005542205.1 formate dehydrogenase subunit gamma -
ACT75_RS10085 () 2069223..2070140 - 918 WP_167555044.1 formate dehydrogenase subunit beta -
ACT75_RS10090 () 2070151..2073240 - 3090 WP_143247869.1 formate dehydrogenase-N subunit alpha -
ACT75_RS10100 () 2073482..2074306 + 825 WP_005542212.1 formate dehydrogenase accessory sulfurtransferase FdhD -
ACT75_RS10105 () 2074355..2075353 + 999 WP_005542214.1 gluconate operon transcriptional repressor GntR -
ACT75_RS10110 () 2075423..2075941 - 519 WP_005542216.1 gluconokinase -
ACT75_RS10115 () 2076159..2077508 + 1350 WP_005542218.1 GntP family permease -
ACT75_RS10120 () 2077681..2079855 + 2175 WP_005542219.1 DNA helicase II -
ACT75_RS10125 () 2079987..2080814 - 828 WP_005542220.1 DNA ligase -
ACT75_RS10130 () 2080991..2081734 - 744 WP_005542222.1 YdcF family protein -
ACT75_RS10135 () 2081747..2082001 - 255 WP_005549367.1 Txe/YoeB family addiction module toxin Toxin Detail
ACT75_RS10140 () 2081998..2082249 - 252 WP_005552753.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin Detail
ACT75_RS10145 () 2082358..2083314 - 957 WP_005542226.1 polysaccharide pyruvyl transferase family protein -
ACT75_RS10150 () 2083311..2084834 - 1524 WP_005542228.1 hypothetical protein -
ACT75_RS10155 () 2084968..2085741 + 774 WP_180267045.1 hypothetical protein VF
ACT75_RS10160 () 2085750..2086940 + 1191 WP_005549375.1 hypothetical protein -
ACT75_RS10165 () 2086940..2087821 + 882 WP_005540377.1 PGL/p-HBAD biosynthesis glycosyltransferase VF
ACT75_RS10170 () 2087896..2088699 + 804 WP_005549377.1 UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase VF
ACT75_RS10175 () 2088701..2089843 + 1143 WP_005549378.1 lytic murein transglycosylase -
ACT75_RS10180 () 2089861..2090664 + 804 WP_005542405.1 exodeoxyribonuclease III -
ACT75_RS10185 () 2090664..2091452 + 789 WP_005542406.1 TIGR01619 family protein -
ACT75_RS12590 () 2091477..2092505 + 1029 WP_005542407.1 dTDP-glucose 4,6-dehydratase 2 VF
ACT75_RS10195 () 2092667..2093407 - 741 WP_005542409.1 hypothetical protein -
ACT75_RS10200 () 2093682..2094335 - 654 WP_005542410.1 GTP cyclohydrolase II -
ACT75_RS10205 () 2094412..2095152 + 741 WP_005542411.1 phosphatase PAP2 family protein -
ACT75_RS10210 () 2095203..2096117 + 915 WP_005542412.1 N-acetylglucosamine kinase -
ACT75_RS12205 () 2096174..2096759 - 586 Protein_2013 DUF1439 domain-containing protein -
ACT75_RS10225 () 2096847..2097482 + 636 WP_005542415.1 hypothetical protein -
ACT75_RS10230 () 2097548..2098288 + 741 WP_005542416.1 protein kinase family protein -
ACT75_RS10235 () 2098497..2099429 - 933 WP_005542418.1 acyl-CoA thioesterase II -
ACT75_RS10245 () 2099680..2101413 - 1734 WP_005542419.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
ACT75_RS10250 () 2101413..2103176 - 1764 WP_032998675.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD -
ACT75_RS10255 () 2103282..2104235 - 954 WP_005542421.1 thioredoxin-disulfide reductase -
ACT75_RS10260 () 2104295..2105152 - 858 WP_005542422.1 co-chaperone YbbN -
ACT75_RS10265 () 2105371..2105797 + 427 Protein_2021 IS4/IS5 family transposase -
ACT75_RS10270 () 2105872..2106603 - 732 WP_005542424.1 molybdopterin-synthase adenylyltransferase MoeB -
ACT75_RS10275 () 2106619..2107833 - 1215 WP_005542426.1 molybdopterin molybdotransferase MoeA -
ACT75_RS10280 () 2107962..2108618 + 657 WP_005542427.1 GTP cyclohydrolase I FolE -
ACT75_RS10285 () 2108719..2110161 - 1443 WP_005542428.1 serine-type D-Ala-D-Ala carboxypeptidase -
ACT75_RS10290 () 2110321..2110797 + 477 WP_005542429.1 transcription elongation factor GreA -
ACT75_RS10295 () 2110873..2111175 - 303 WP_005542430.1 ribosome assembly RNA-binding protein YhbY -
ACT75_RS10300 () 2111343..2111642 + 300 WP_005542431.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
ACT75_RS10305 () 2111639..2111935 + 297 WP_005542432.1 putative addiction module antidote protein Antitoxin Detail
ACT75_RS10310 () 2111968..2112582 - 615 WP_005542433.1 riboflavin synthase -
ACT75_RS10315 () 2112609..2114006 + 1398 WP_005542434.1 MATE family efflux transporter -
ACT75_RS10320 () 2114278..2116416 + 2139 WP_005542435.1 TonB-dependent siderophore receptor -
ACT75_RS10325 () 2116470..2118215 + 1746 WP_005542436.1 ABC transporter ATP-binding protein/permease -
ACT75_RS10330 () 2118329..2118808 - 480 WP_005542438.1 Cys-tRNA(Pro) deacylase -
ACT75_RS10335 () 2118869..2119840 + 972 WP_005542439.1 oxidoreductase -
ACT75_RS10340 () 2120446..2122179 - 1734 WP_005550377.1 arginine--tRNA ligase -
ACT75_RS10345 () 2122276..2122863 + 588 WP_014702560.1 VOC family protein -
ACT75_RS10350 () 2122905..2123360 + 456 WP_005542443.1 glycine zipper 2TM domain-containing protein -
ACT75_RS10355 () 2123501..2124583 + 1083 WP_005542444.1 peptide chain release factor 1 -
ACT75_RS10360 () 2124623..2125522 + 900 WP_005542445.1 peptide chain release factor N(5)-glutamine methyltransferase -
ACT75_RS10365 () 2125532..2126386 + 855 WP_005542446.1 2-dehydro-3-deoxyphosphooctonate aldolase VF
ACT75_RS10370 () 2126566..2127075 + 510 WP_005542447.1 Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase VF
ACT75_RS10375 () 2127244..2127429 + 186 WP_005581143.1 hypothetical protein -
ACT75_RS10380 () 2127473..2127724 - 252 WP_005542449.1 YcgL domain-containing protein -
ACT75_RS10385 () 2127808..2128470 + 663 WP_005542450.1 septum site-determining protein MinC -
ACT75_RS10390 () 2128492..2129037 - 546 WP_005542451.1 hypothetical protein -
ACT75_RS10395 () 2129261..2129728 - 468 WP_005542452.1 phosphohistidine phosphatase SixA -
ACT75_RS10400 () 2129741..2131078 - 1338 WP_005551246.1 phosphoglucosamine mutase -
ACT75_RS10405 () 2131106..2131933 - 828 WP_005552864.1 dihydropteroate synthase -
ACT75_RS10410 () 2132103..2133623 - 1521 WP_155719825.1 IS3 family transposase ISBce15 Transposase
ACT75_RS10415 () 2133665..2134039 - 375 WP_061866548.1 IS3 family transposase ISMmy3 Transposase
ACT75_RS12595 () 2134162..2134350 - 189 WP_143106533.1 hypothetical protein -
ACT75_RS10420 () 2134524..2134973 + 450 WP_005544663.1 type VI secretion protein ImpA -
ACT75_RS12600 () 2135040..2135111 - 72 WP_109091998.1 IS3 family transposase -
ACT75_RS12885 () 2135206..2135579 - 374 Protein_2055 transposase -
ACT75_RS10425 () 2135681..2137147 - 1467 WP_005544504.1 IMP dehydrogenase -
ACT75_RS10430 () 2137289..2138217 + 929 Protein_2057 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
ACT75_RS10435 () 2138308..2138511 + 204 WP_005551084.1 glycine zipper 2TM domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance