MGE detailed information
MGE type: Conjugative plasmid MGE length: 146575 bp
Accession: NZ_CP010187 Location: 1..146575 Organism: Escherichia coli strain M6 Replicon: plasmid A
Accession: NZ_CP010187 Location: 1..146575 Organism: Escherichia coli strain M6 Replicon: plasmid A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RG56_RS26855 () | 46..465 | + | 420 | Protein_0 | IS110 family transposase | - |
| RG56_RS26860 () | 493..819 | - | 327 | Protein_1 | protein ImpB | - |
| RG56_RS26865 () | 819..1256 | - | 438 | WP_073519984.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| RG56_RS26870 () | 1253..1501 | - | 249 | WP_073519983.1 | DinI-like family protein | - |
| RG56_RS26880 () | 1895..2791 | + | 897 | WP_106423823.1 | DUF1281 domain-containing protein | - |
| RG56_RS26885 () | 3106..4032 | + | 927 | WP_073519982.1 | hypothetical protein | - |
| RG56_RS26890 () | 4157..5029 | - | 873 | WP_073519981.1 | HTH-type transcriptional regulator MetR | VF |
| RG56_RS26895 () | 5154..5861 | + | 708 | WP_073519980.1 | AzlC family ABC transporter permease | - |
| RG56_RS26900 () | 5858..6166 | + | 309 | WP_073519979.1 | AzlD domain-containing protein | - |
| RG56_RS26905 () | 6209..6904 | + | 696 | WP_073519978.1 | alpha/beta hydrolase | - |
| RG56_RS28365 () | 7007..7979 | - | 973 | Protein_10 | IS110 family transposase ISOt5 | Transposase |
| RG56_RS26920 () | 8558..9034 | + | 477 | Protein_11 | antirestriction protein ArdA | - |
| RG56_RS29365 () | 9096..9233 | + | 138 | WP_172944237.1 | hypothetical protein | - |
| RG56_RS26925 () | 9480..9734 | + | 255 | WP_160537948.1 | DNA polymerase III subunit theta | - |
| RG56_RS29010 () | 9911..10132 | - | 222 | WP_154813206.1 | hypothetical protein | - |
| RG56_RS29370 () | 10197..10346 | - | 150 | WP_157920373.1 | hypothetical protein | - |
| RG56_RS26930 () | 10417..10974 | + | 558 | WP_073519975.1 | single-stranded DNA-binding protein | - |
| RG56_RS26935 () | 11026..11268 | + | 243 | WP_073519974.1 | DUF905 domain-containing protein | - |
| RG56_RS26940 () | 11338..13335 | + | 1998 | WP_073519973.1 | ParB/RepB/Spo0J family partition protein | - |
| RG56_RS26945 () | 13376..13810 | + | 435 | WP_097455818.1 | conjugation system SOS inhibitor PsiB | - |
| RG56_RS26950 () | 13807..14536 | + | 730 | Protein_20 | plasmid SOS inhibition protein A | - |
| RG56_RS26955 () | 14533..14847 | + | 315 | WP_073519971.1 | theronine dehydrogenase | - |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| - () | 14827..15004 | + | 178 | NuclAT_0 | - | Antitoxin Detail |
| RG56_RS26965 () | 15057..15218 | + | 162 | WP_073519970.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| RG56_RS28370 () | 15392..15766 | + | 375 | WP_171769349.1 | hypothetical protein | - |
| RG56_RS29020 () | 15951..16362 | - | 412 | Protein_24 | hypothetical protein | - |
| RG56_RS26985 () | 16659..17003 | + | 345 | WP_073519969.1 | hypothetical protein | - |
| RG56_RS26990 () | 17147..17968 | + | 822 | WP_073519968.1 | DUF945 domain-containing protein | - |
| RG56_RS26995 () | 18264..18773 | - | 510 | WP_073519994.1 | hypothetical protein | VF |
| RG56_RS27000 () | 19197..19583 | + | 387 | WP_073519967.1 | relaxosome protein TraM | - |
| RG56_RS27005 () | 19772..20194 | + | 423 | WP_073519966.1 | PAS domain-containing protein | - |
| RG56_RS27010 () | 20551..20778 | + | 228 | WP_073519965.1 | conjugal transfer relaxosome protein TraY | - |
| RG56_RS27015 () | 20812..21171 | + | 360 | WP_073519964.1 | type IV conjugative transfer system pilin TraA | - |
| RG56_RS27020 () | 21186..21497 | + | 312 | WP_073519963.1 | type IV conjugative transfer system protein TraL | - |
| RG56_RS27025 () | 21519..22085 | + | 567 | WP_073519962.1 | type IV conjugative transfer system protein TraE | - |
| RG56_RS27030 () | 22096..22803 | + | 708 | WP_149025695.1 | type-F conjugative transfer system secretin TraK | - |
| RG56_RS27035 () | 22803..24251 | + | 1449 | WP_073519960.1 | conjugal transfer protein TraB | - |
| RG56_RS27040 () | 24220..24804 | + | 585 | WP_073519959.1 | conjugal transfer protein TraP | - |
| RG56_RS27045 () | 24758..25111 | + | 354 | WP_077897972.1 | conjugal transfer protein TrbD | - |
| RG56_RS27050 () | 25108..25623 | + | 516 | WP_073519958.1 | type IV conjugative transfer system lipoprotein TraV | - |
| RG56_RS27055 () | 25758..25979 | + | 222 | WP_073519957.1 | conjugal transfer protein TraR | - |
| RG56_RS27060 () | 25972..26448 | + | 477 | WP_073519956.1 | hypothetical protein | - |
| RG56_RS27065 () | 26445..26915 | + | 471 | WP_073519955.1 | hypothetical protein | - |
| RG56_RS27070 () | 26912..27307 | + | 396 | WP_073519954.1 | hypothetical protein | - |
| RG56_RS27075 () | 27325..29952 | + | 2628 | WP_073519953.1 | type IV secretion system protein TraC | - |
| RG56_RS27080 () | 29949..30335 | + | 387 | WP_073519952.1 | type-F conjugative transfer system protein TrbI | - |
| RG56_RS27085 () | 30332..30964 | + | 633 | WP_073519951.1 | type-F conjugative transfer system protein TraW | - |
| RG56_RS27090 () | 30961..31953 | + | 993 | WP_073519950.1 | conjugal transfer pilus assembly protein TraU | - |
| RG56_RS27095 () | 31962..32600 | + | 639 | WP_073519949.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| RG56_RS27100 () | 32597..32977 | + | 381 | WP_073519948.1 | hypothetical protein | - |
| RG56_RS27105 () | 33213..35096 | + | 1884 | WP_077897973.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| RG56_RS27110 () | 35108..35575 | + | 468 | WP_073519947.1 | hypothetical protein | - |
| RG56_RS27115 () | 35586..36329 | + | 744 | WP_073519946.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| RG56_RS27120 () | 36343..36708 | + | 366 | WP_073519945.1 | hypothetical protein | - |
| RG56_RS27130 () | 37094..37381 | + | 288 | WP_073519943.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| RG56_RS27135 () | 37362..37916 | + | 555 | WP_073519942.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| RG56_RS27140 () | 37929..38420 | + | 492 | WP_073519941.1 | hypothetical protein | - |
| RG56_RS27150 () | 38825..40243 | + | 1419 | WP_073519939.1 | conjugal transfer protein TraH | - |
| RG56_RS27155 () | 40240..43092 | + | 2853 | WP_073519938.1 | conjugal transfer mating pair stabilization protein TraG | - |
| RG56_RS27160 () | 43113..43610 | + | 498 | WP_073519937.1 | surface exclusion protein | - |
| RG56_RS27165 () | 43642..44373 | + | 732 | WP_123006582.1 | complement resistance protein TraT | - |
| RG56_RS27170 () | 44970..47123 | + | 2154 | WP_073519936.1 | type IV conjugative transfer system coupling protein TraD | - |
| RG56_RS27175 () | 47123..52393 | + | 5271 | WP_073519935.1 | Multifunctional conjugation protein TraI | Relaxase |
| RG56_RS27180 () | 52410..53144 | + | 735 | WP_073519934.1 | conjugal transfer pilus acetylase TraX | - |
| RG56_RS27185 () | 53199..53759 | + | 561 | Protein_63 | fertility inhibition protein FinO | - |
| RG56_RS27190 () | 53895..54101 | + | 207 | WP_073519933.1 | hypothetical protein | - |
| RG56_RS29530 () | 54373..54474 | - | 102 | Protein_65 | transposase | - |
| RG56_RS27195 () | 54621..55505 | + | 885 | WP_034173833.1 | alpha/beta hydrolase | - |
| RG56_RS27200 () | 55530..56258 | - | 729 | WP_034173832.1 | transcriptional regulator NanR | - |
| RG56_RS27205 () | 56328..57413 | + | 1086 | WP_077897982.1 | hypothetical protein | - |
| RG56_RS27210 () | 57550..58449 | + | 900 | WP_073519990.1 | N-acetylneuraminate lyase | - |
| RG56_RS27215 () | 58509..59384 | + | 876 | WP_073519989.1 | N-acetylmannosamine kinase | - |
| RG56_RS27220 () | 59455..60921 | + | 1467 | WP_073519932.1 | MFS transporter | - |
| RG56_RS27225 () | 60937..61746 | + | 810 | WP_073519931.1 | alpha/beta hydrolase | - |
| RG56_RS27230 () | 61800..62510 | + | 711 | WP_073519930.1 | N-acetylneuraminic acid channel protein | - |
| RG56_RS27235 () | 62520..63629 | + | 1110 | WP_073519929.1 | N-acetylneuraminate epimerase | - |
| RG56_RS27240 () | 64150..64371 | - | 222 | Protein_75 | IS1 family transposase IS1N | Transposase |
| RG56_RS27245 () | 64370..64558 | - | 189 | Protein_76 | transposase | - |
| RG56_RS27255 () | 64962..65534 | + | 573 | WP_073519927.1 | hypothetical protein | - |
| RG56_RS27260 () | 65568..66788 | + | 1221 | WP_073519926.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| RG56_RS27265 () | 66790..68943 | + | 2154 | WP_073519925.1 | peptidase domain-containing ABC transporter | - |
| RG56_RS27270 () | 68987..69721 | + | 735 | WP_073519924.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| RG56_RS27275 () | 69776..70336 | + | 561 | Protein_81 | fertility inhibition protein FinO | - |
| RG56_RS29375 () | 70491..70685 | - | 195 | WP_157916191.1 | hypothetical protein | - |
| RG56_RS27285 () | 70925..71385 | + | 461 | Protein_83 | thermonuclease family protein | - |
| RG56_RS27290 () | 71431..71640 | + | 210 | WP_032334801.1 | hemolysin expression modulator Hha | - |
| RG56_RS27295 () | 71678..72268 | + | 591 | WP_032334802.1 | DUF2726 domain-containing protein | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| - () | 72441..72497 | - | 57 | NuclAT_1 | - | - |
| RG56_RS27305 () | 72546..72695 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | - |
| RG56_RS27310 () | 72896..73153 | + | 258 | WP_073519922.1 | replication regulatory protein RepA | - |
| RG56_RS27320 () | 73385..73459 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| RG56_RS27325 () | 73452..74309 | + | 858 | WP_073528052.1 | incFII family plasmid replication initiator RepA | - |
| RG56_RS29380 () | 75011..75169 | + | 159 | WP_073519919.1 | hypothetical protein | - |
| RG56_RS27345 () | 75224..75493 | + | 270 | WP_073519918.1 | hypothetical protein | Antitoxin Detail |
| RG56_RS27350 () | 75490..75705 | + | 216 | WP_073519917.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG56_RS27355 () | 75857..76162 | + | 306 | WP_073521420.1 | hypothetical protein | - |
| RG56_RS27360 () | 76159..76431 | - | 273 | WP_046201741.1 | hypothetical protein | - |
| RG56_RS29385 () | 76424..76747 | - | 324 | Protein_95 | recombinase family protein | - |
| RG56_RS27380 () | 78030..78665 | + | 636 | WP_073519914.1 | CPBP family intramembrane metalloprotease | - |
| RG56_RS27385 () | 78768..80021 | + | 1254 | WP_073519913.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| RG56_RS27390 () | 80021..82210 | + | 2190 | WP_073519912.1 | peptidase domain-containing ABC transporter | - |
| RG56_RS27400 () | 82722..85769 | - | 3048 | Protein_99 | Tn3 family transposase ISPsy42 | Transposase |
| RG56_RS27405 () | 85919..86496 | + | 578 | Protein_100 | Tn3 family transposase ISPsy39 | Transposase |
| RG56_RS27410 () | 86489..86761 | + | 273 | WP_046201741.1 | hypothetical protein | - |
| RG56_RS27415 () | 86799..86993 | - | 195 | Protein_102 | hypothetical protein | - |
| RG56_RS27420 () | 87678..88097 | + | 420 | WP_073519911.1 | Exc2 family lipoprotein | - |
| RG56_RS27425 () | 88467..88820 | + | 354 | WP_077897977.1 | hypothetical protein | - |
| RG56_RS27430 () | 88832..89230 | + | 399 | WP_073519910.1 | hypothetical protein | - |
| RG56_RS27440 () | 89664..90238 | - | 575 | Protein_106 | IS481 family transposase ISErsp1 | Transposase |
| RG56_RS27445 () | 90322..90507 | - | 186 | WP_077897978.1 | LacI family transcriptional regulator | - |
| RG56_RS27450 () | 90541..90918 | - | 378 | WP_157916187.1 | GntR family transcriptional regulator | - |
| RG56_RS27455 () | 91711..95814 | + | 4104 | WP_073528053.1 | Serine protease pic autotransporter | VF |
| RG56_RS29060 () | 96056..97132 | + | 1077 | Protein_110 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG56_RS29065 () | 97154..98347 | + | 1194 | WP_095374788.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| RG56_RS27465 () | 98572..99210 | - | 639 | WP_073519905.1 | ParB N-terminal domain-containing protein | - |
| RG56_RS27470 () | 99195..100427 | - | 1233 | WP_073519904.1 | phosphoadenosine phosphosulfate reductase | - |
| RG56_RS28390 () | 100951..101164 | + | 214 | Protein_114 | IS1 family transposase | - |
| RG56_RS28395 () | 101313..102070 | + | 758 | Protein_115 | IS3 family transposase | - |
| RG56_RS28400 () | 102102..102365 | - | 264 | WP_077897983.1 | HNH endonuclease | - |
| RG56_RS27495 () | 102418..103430 | + | 1013 | Protein_117 | IS21 family transposase IS100kyp | Transposase |
| RG56_RS27500 () | 103441..104196 | + | 756 | WP_187655892.1 | IS21 family transposase IS100kyp | Transposase |
| RG56_RS27505 () | 104280..104789 | - | 510 | Protein_119 | HNH endonuclease | - |
| RG56_RS29070 () | 104912..105152 | - | 241 | Protein_120 | transposase zinc-binding domain-containing protein | - |
| RG56_RS27515 () | 105938..106237 | + | 300 | WP_073519900.1 | Major pilu subunit operon regulatory protein PapB | VF |
| RG56_RS27520 () | 106245..106787 | + | 543 | WP_073519899.1 | hypothetical protein | VF |
| RG56_RS27525 () | 106802..109246 | + | 2445 | WP_073519898.1 | Outer membrane usher protein YraJ | VF |
| RG56_RS27530 () | 109239..110015 | + | 777 | WP_073519897.1 | Chaperone protein FaeE | VF |
| RG56_RS27535 () | 110050..110541 | + | 492 | WP_073519896.1 | hypothetical protein | VF |
| RG56_RS27540 () | 110763..111560 | + | 798 | WP_073519895.1 | hypothetical protein | - |
| RG56_RS27545 () | 111758..112555 | + | 798 | WP_073519894.1 | hypothetical protein | VF |
| RG56_RS27550 () | 112585..113349 | + | 765 | WP_073519893.1 | hypothetical protein | VF |
| RG56_RS27555 () | 113366..114127 | + | 762 | WP_073519892.1 | hypothetical protein | VF |
| RG56_RS27560 () | 114369..114653 | - | 285 | WP_077897980.1 | Major pilu subunit operon regulatory protein PapB | VF |
| RG56_RS27565 () | 114737..118666 | - | 3930 | WP_073519890.1 | Serine protease EspC | VF |
| RG56_RS27575 () | 119588..120013 | + | 426 | Protein_132 | IS3 family transposase ISEc16 | Transposase |
| RG56_RS28405 () | 120289..121288 | + | 1000 | Protein_133 | colicin transporter | - |
| RG56_RS27600 () | 121618..121887 | + | 270 | Protein_134 | transcriptional regulator | - |
| RG56_RS29080 () | 122223..122329 | + | 107 | Protein_135 | IS110 family transposase | - |
| RG56_RS27605 () | 122331..122540 | + | 210 | Protein_136 | hypothetical protein | - |
| RG56_RS27610 () | 122793..123642 | - | 850 | Protein_137 | hypothetical protein | - |
| RG56_RS27620 () | 124324..124470 | + | 147 | WP_073519886.1 | serine/threonine protein kinase | - |
| RG56_RS27625 () | 124633..125373 | + | 741 | WP_073519885.1 | site-specific integrase | - |
| RG56_RS27630 () | 125658..126635 | - | 978 | WP_000361618.1 | RepB family plasmid replication initiator protein | - |
| RG56_RS29085 () | 127285..127565 | - | 281 | Protein_141 | IS3 family transposase ISKpn37 | Transposase |
| RG56_RS27650 () | 127564..127851 | - | 288 | WP_001270417.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| RG56_RS27655 () | 127848..128099 | - | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| RG56_RS27660 () | 128264..128476 | - | 213 | WP_032334873.1 | hypothetical protein | - |
| RG56_RS27670 () | 128850..130055 | + | 1206 | WP_000817644.1 | Plasmid partition protein A | VF |
| RG56_RS27675 () | 130052..131014 | + | 963 | WP_000756325.1 | ParB/RepB/Spo0J family partition protein | - |
| RG56_RS28410 () | 131248..132004 | + | 757 | Protein_147 | IS4 family transposase ISEc13 | Transposase |
| RG56_RS29390 () | 132118..132593 | + | 476 | Protein_148 | DUF1281 domain-containing protein | - |
| RG56_RS27705 () | 132933..134078 | + | 1146 | WP_073519881.1 | IS21 family transposase IS21 | Transposase |
| RG56_RS27710 () | 134078..134626 | + | 549 | Protein_150 | IS21 family transposase IS21 | Transposase |
| RG56_RS27720 () | 134938..136710 | + | 1773 | WP_073519780.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| RG56_RS27725 () | 136723..145842 | + | 9120 | Protein_152 | contact-dependent inhibition effector tRNA nuclease | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|