MGE detailed information
MGE type: Conjugative plasmid MGE length: 83922 bp
Accession: NZ_CP010138 Location: 1..83922 Organism: Escherichia coli strain D2 Replicon: plasmid A
Accession: NZ_CP010138 Location: 1..83922 Organism: Escherichia coli strain D2 Replicon: plasmid A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RG35_RS26220 () | 651..885 | + | 235 | Protein_0 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| RG35_RS24930 () | 1149..2129 | + | 981 | WP_000019449.1 | IS5 family transposase ISKpn26 | Transposase |
| RG35_RS26720 () | 2264..2494 | + | 231 | WP_094193301.1 | hypothetical protein | - |
| RG35_RS24940 () | 2617..2967 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| RG35_RS24945 () | 2970..3932 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| RG35_RS24950 () | 4079..4372 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| RG35_RS24960 () | 4449..5132 | + | 684 | WP_000085883.1 | DNA methylase | - |
| RG35_RS24965 () | 5133..5354 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| RG35_RS24970 () | 5368..5802 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| RG35_RS27240 () | 5853..6629 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| RG35_RS24985 () | 7170..7472 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| RG35_RS24990 () | 7519..7941 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| RG35_RS26725 () | 7938..8162 | + | 225 | WP_073544445.1 | hypothetical protein | - |
| RG35_RS25000 () | 8155..8493 | + | 339 | WP_073544446.1 | class I SAM-dependent methyltransferase | - |
| RG35_RS25025 () | 9363..9890 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| RG35_RS25030 () | 9946..10179 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| RG35_RS25035 () | 10238..12196 | + | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| RG35_RS25040 () | 12251..12685 | + | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| RG35_RS25045 () | 12682..13401 | + | 720 | WP_001276234.1 | plasmid SOS inhibition protein A | - |
| RG35_RS27090 () | 13413..13601 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 13413..13637 | + | 225 | NuclAT_0 | - | - |
| - () | 13413..13637 | + | 225 | NuclAT_0 | - | - |
| - () | 13413..13637 | + | 225 | NuclAT_0 | - | - |
| - () | 13413..13637 | + | 225 | NuclAT_0 | - | - |
| - () | 13570..13635 | + | 66 | - | - | Antitoxin Detail |
| RG35_RS25055 () | 13681..13839 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| RG35_RS25075 () | 14758..15045 | + | 288 | WP_000107537.1 | hypothetical protein | - |
| RG35_RS25080 () | 15166..15987 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| RG35_RS25085 () | 16284..16931 | - | 648 | WP_000614282.1 | hypothetical protein | VF |
| RG35_RS25095 () | 17217..17600 | + | 384 | WP_001151564.1 | relaxosome protein TraM | - |
| RG35_RS25100 () | 17794..18480 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| RG35_RS25105 () | 18574..18801 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| RG35_RS25110 () | 18835..19197 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| RG35_RS25115 () | 19202..19513 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| RG35_RS25120 () | 19535..20101 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| RG35_RS25125 () | 20112..20816 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| RG35_RS25130 () | 20816..22243 | + | 1428 | WP_000146638.1 | conjugal transfer protein TraB | - |
| RG35_RS25135 () | 22233..22817 | + | 585 | WP_000002795.1 | conjugal transfer protein TraP | - |
| RG35_RS25140 () | 22771..23124 | + | 354 | WP_071528018.1 | conjugal transfer protein TrbD | - |
| RG35_RS25145 () | 23117..23368 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| RG35_RS25150 () | 23365..23880 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| RG35_RS25155 () | 24015..24236 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| RG35_RS25160 () | 24396..27023 | + | 2628 | WP_001064239.1 | type IV secretion system protein TraC | - |
| RG35_RS25165 () | 27020..27406 | + | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| RG35_RS25170 () | 27403..28035 | + | 633 | WP_001203717.1 | type-F conjugative transfer system protein TraW | - |
| RG35_RS25175 () | 28032..29024 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| RG35_RS25180 () | 29054..29359 | + | 306 | WP_000224411.1 | hypothetical protein | - |
| RG35_RS25185 () | 29368..30006 | + | 639 | WP_001080257.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| RG35_RS25190 () | 30003..31811 | + | 1809 | WP_000821863.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| RG35_RS25195 () | 31838..32095 | + | 258 | WP_000864320.1 | conjugal transfer protein TrbE | - |
| RG35_RS25200 () | 32088..32831 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| RG35_RS25205 () | 32847..33185 | + | 339 | WP_001287905.1 | conjugal transfer protein TrbA | - |
| RG35_RS25210 () | 33312..33596 | + | 285 | WP_001448202.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| RG35_RS25215 () | 33583..34128 | + | 546 | WP_000059824.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| RG35_RS25220 () | 34058..34399 | + | 342 | WP_001448115.1 | P-type conjugative transfer protein TrbJ | - |
| RG35_RS25225 () | 34347..34772 | + | 426 | WP_001448114.1 | F-type conjugal transfer protein TrbF | - |
| RG35_RS25230 () | 34759..36132 | + | 1374 | WP_001137364.1 | conjugal transfer protein TraH | - |
| RG35_RS25235 () | 36129..38948 | + | 2820 | WP_001007057.1 | conjugal transfer mating pair stabilization protein TraG | - |
| RG35_RS25240 () | 38967..39464 | + | 498 | WP_000605861.1 | hypothetical protein | - |
| RG35_RS25245 () | 39496..40227 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| RG35_RS25250 () | 40480..42669 | + | 2190 | WP_001419971.1 | type IV conjugative transfer system coupling protein TraD | - |
| RG35_RS25255 () | 42669..47939 | + | 5271 | WP_000986934.1 | Multifunctional conjugation protein TraI | Relaxase |
| RG35_RS25260 () | 47959..48705 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| RG35_RS25265 () | 48764..49624 | + | 861 | WP_000704528.1 | putative protein YcjY | VF |
| RG35_RS25270 () | 49727..50287 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| RG35_RS25275 () | 50416..50628 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| RG35_RS25280 () | 50873..51334 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| RG35_RS25285 () | 51380..51589 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| RG35_RS25290 () | 51627..52217 | + | 591 | WP_000766805.1 | DUF2726 domain-containing protein | - |
| RG35_RS25295 () | 52457..52717 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| RG35_RS25305 () | 52942..53016 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| RG35_RS25310 () | 53009..53866 | + | 858 | WP_000130647.1 | incFII family plasmid replication initiator RepA | - |
| RG35_RS27245 () | 54567..54707 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| RG35_RS25320 () | 54805..55458 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| RG35_RS27095 () | 55551..55808 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| RG35_RS25330 () | 55741..56142 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| RG35_RS25335 () | 56427..57737 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| RG35_RS26235 () | 57766..57864 | + | 99 | Protein_72 | IS1 family transposase | - |
| RG35_RS25345 () | 58014..58874 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| RG35_RS25350 () | 59173..59877 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| RG35_RS25355 () | 59930..60436 | + | 507 | Protein_75 | transposase | - |
| RG35_RS25360 () | 60445..61305 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| RG35_RS25365 () | 61337..62536 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| RG35_RS25370 () | 62642..63268 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| RG35_RS25375 () | 63300..63536 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| RG35_RS25380 () | 63590..64426 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| RG35_RS25385 () | 64426..65229 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| RG35_RS25390 () | 65290..66105 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| RG35_RS25400 () | 66413..66589 | - | 177 | Protein_83 | replication protein C | - |
| RG35_RS25405 () | 66650..67354 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| RG35_RS25410 () | 67476..68381 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| RG35_RS25415 () | 68378..69616 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| RG35_RS25420 () | 69616..70200 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| RG35_RS25430 () | 70693..71457 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| RG35_RS27100 () | 71575..71640 | - | 66 | Protein_89 | EAL domain-containing protein | - |
| RG35_RS25440 () | 71684..71989 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| RG35_RS25445 () | 72000..73205 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| RG35_RS25450 () | 73361..73564 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| RG35_RS25460 () | 73692..74531 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| RG35_RS25465 () | 74525..74872 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| RG35_RS25470 () | 75078..75866 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| RG35_RS25475 () | 75997..76470 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| RG35_RS25480 () | 76628..77641 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| RG35_RS27250 () | 77844..77939 | + | 96 | Protein_98 | EAL domain-containing protein | - |
| RG35_RS25490 () | 77993..78697 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| RG35_RS25495 () | 78744..79043 | - | 300 | WP_052982969.1 | hypothetical protein | - |
| RG35_RS25500 () | 79056..79916 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| RG35_RS25505 () | 80059..81021 | + | 963 | Protein_102 | IS4 family transposase IS10R | Transposase |
| RG35_RS25510 () | 81131..82093 | + | 963 | Protein_103 | IS4 family transposase IS10R | Transposase |
| RG35_RS25515 () | 82203..83108 | + | 906 | Protein_104 | IS4 family transposase IS10R | Transposase |
| RG35_RS25520 () | 83157..83861 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|