MGE detailed information
MGE type: Conjugative plasmid MGE length: 120653 bp
Accession: NZ_CP008715 Location: 1..120653 Organism: Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis Replicon: plasmid pEC648_1
Accession: NZ_CP008715 Location: 1..120653 Organism: Escherichia coli strain ST648 isolate Pleural Effusion of Patients with Empyema Thoracis Replicon: plasmid pEC648_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FH07_RS24950 () | 17..838 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| FH07_RS24955 () | 957..1244 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| FH07_RS28905 () | 1269..1475 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| FH07_RS24970 () | 1796..2767 | + | 972 | WP_000082158.1 | IS110 family transposase ISSm3 | Transposase |
| FH07_RS24980 () | 3255..3446 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| FH07_RS24985 () | 3443..3865 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| FH07_RS24990 () | 3912..4214 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| FH07_RS28660 () | 4754..5530 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| FH07_RS25000 () | 5581..6015 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| FH07_RS25005 () | 6029..6250 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| FH07_RS25010 () | 6251..6934 | - | 684 | WP_000086185.1 | DNA methylase | - |
| FH07_RS28060 () | 7011..7315 | - | 305 | Protein_11 | hypothetical protein | - |
| FH07_RS25020 () | 7319..8221 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| FH07_RS25025 () | 8831..9802 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FH07_RS25030 () | 9802..10968 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| FH07_RS25035 () | 11556..12311 | - | 756 | WP_024946706.1 | replication initiation protein RepE | - |
| FH07_RS25040 () | 13085..13891 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| FH07_RS25045 () | 13892..14197 | - | 306 | WP_060684530.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| FH07_RS25050 () | 14199..14417 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| FH07_RS25055 () | 14984..15496 | + | 513 | WP_000151784.1 | hypothetical protein | - |
| FH07_RS25060 () | 15530..16663 | - | 1134 | WP_001542067.1 | DUF3800 domain-containing protein | - |
| FH07_RS28665 () | 16830..17604 | - | 775 | Protein_21 | hypothetical protein | - |
| FH07_RS25075 () | 17617..18117 | - | 501 | WP_000528931.1 | hypothetical protein | - |
| FH07_RS25080 () | 18382..18612 | + | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| FH07_RS25085 () | 18609..19025 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FH07_RS25090 () | 19070..22865 | - | 3796 | Protein_25 | pcar | - |
| FH07_RS25095 () | 23246..23476 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| FH07_RS25100 () | 23473..23889 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FH07_RS25105 () | 23964..25529 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| FH07_RS25110 () | 25514..26483 | + | 970 | Protein_29 | DNA helicase UvrD | - |
| FH07_RS27290 () | 26737..27434 | - | 698 | Protein_30 | IS1 family transposase IS1S | Transposase |
| FH07_RS25120 () | 27790..28704 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| FH07_RS25125 () | 28704..29531 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| FH07_RS25130 () | 29528..30385 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| FH07_RS25135 () | 30382..31239 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| FH07_RS28070 () | 31473..31730 | - | 258 | Protein_35 | Tn3 family transposase | - |
| FH07_RS25140 () | 31728..32141 | + | 414 | Protein_36 | phosphopyruvate hydratase | - |
| FH07_RS25150 () | 32482..32862 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| FH07_RS25155 () | 33242..34435 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| FH07_RS25160 () | 34571..36295 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| FH07_RS25165 () | 36296..37243 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| FH07_RS25170 () | 37243..38985 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| FH07_RS25175 () | 38982..40259 | + | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| FH07_RS25180 () | 40341..42542 | + | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| FH07_RS25185 () | 42922..43619 | + | 698 | Protein_44 | IS1 family transposase IS1S | Transposase |
| FH07_RS25190 () | 43799..44312 | - | 514 | Protein_45 | DUF4113 domain-containing protein | - |
| FH07_RS28670 () | 44373..44477 | - | 105 | Protein_46 | AAA family ATPase | - |
| FH07_RS25195 () | 44479..44802 | - | 324 | Protein_47 | IS21 family transposase IS21 | Transposase |
| FH07_RS25210 () | 45548..46525 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| FH07_RS25215 () | 46810..47550 | - | 741 | WP_060684531.1 | tyrosine-type recombinase/integrase | - |
| FH07_RS28675 () | 47671..47853 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| FH07_RS27315 () | 48196..48503 | - | 308 | Protein_51 | type II toxin-antitoxin system ParD family antitoxin | - |
| FH07_RS25235 () | 48996..50166 | + | 1171 | Protein_52 | hypothetical protein | - |
| FH07_RS28680 () | 50199..50327 | + | 129 | Protein_53 | IS481 family transposase | - |
| FH07_RS25240 () | 50362..50655 | - | 294 | WP_001105060.1 | hypothetical protein | - |
| FH07_RS25245 () | 50761..51036 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| FH07_RS25250 () | 51036..51320 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| FH07_RS25255 () | 51925..52677 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| FH07_RS25260 () | 52723..53675 | - | 953 | Protein_58 | 2-keto-3-deoxygluconate transporter | - |
| FH07_RS25265 () | 53708..54088 | - | 381 | WP_024946717.1 | Rid family detoxifying hydrolase | - |
| FH07_RS25270 () | 54113..55003 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| FH07_RS25275 () | 55236..55430 | - | 195 | WP_000796505.1 | hypothetical protein | - |
| FH07_RS25280 () | 55404..55844 | + | 441 | Protein_62 | zinc-binding dehydrogenase | - |
| FH07_RS25285 () | 55975..56853 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| FH07_RS25290 () | 56843..57730 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| FH07_RS25295 () | 57741..58565 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| FH07_RS25300 () | 58571..59644 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| FH07_RS25305 () | 59637..60947 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| FH07_RS25310 () | 61006..61314 | - | 309 | Protein_68 | IS4 family transposase ISEc13 | Transposase |
| FH07_RS27325 () | 61391..61624 | - | 234 | Protein_69 | Tn3 family transposase | - |
| FH07_RS25315 () | 61646..62842 | - | 1197 | Protein_70 | IS3 family transposase | - |
| FH07_RS25325 () | 62867..63571 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| FH07_RS25330 () | 63625..67212 | + | 3588 | Protein_72 | Multifunctional conjugation protein TraI | Relaxase |
| FH07_RS25335 () | 67232..67978 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| FH07_RS25340 () | 68033..68593 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| FH07_RS25345 () | 68725..68937 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| FH07_RS25350 () | 69450..69736 | + | 287 | Protein_76 | DUF2726 domain-containing protein | - |
| - () | 69703..69763 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69703..69763 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69703..69763 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69703..69763 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| FH07_RS25355 () | 69808..69942 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FH07_RS27335 () | 70239..70349 | + | 111 | Protein_78 | replication protein | - |
| FH07_RS25360 () | 70418..71200 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| FH07_RS25365 () | 71197..72219 | - | 1023 | WP_000255944.1 | IS21 family transposase IS100kyp | Transposase |
| FH07_RS27340 () | 72300..72452 | + | 153 | WP_072258247.1 | replication protein A | - |
| FH07_RS29035 () | 72558..72692 | + | 135 | Protein_82 | protein CopA/IncA | - |
| FH07_RS25370 () | 72689..72763 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| FH07_RS25375 () | 72756..73613 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| FH07_RS28690 () | 74553..75208 | + | 656 | Protein_85 | CPBP family intramembrane metalloprotease | - |
| FH07_RS28695 () | 75264..75521 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FH07_RS25390 () | 75454..75855 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FH07_RS25395 () | 76140..76337 | + | 198 | Protein_88 | DUF262 domain-containing protein | - |
| FH07_RS27355 () | 76392..76490 | + | 99 | Protein_89 | IS1 family transposase | - |
| FH07_RS25400 () | 76640..77501 | - | 862 | Protein_90 | Beta-lactamase TEM | ARG |
| FH07_RS25405 () | 77684..78241 | - | 558 | WP_060684534.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FH07_RS25415 () | 78565..79269 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FH07_RS25420 () | 79334..80014 | - | 681 | Protein_93 | IS91 family transposase ISAzo26 | Transposase |
| FH07_RS25425 () | 80172..80645 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| FH07_RS25430 () | 80776..81564 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| FH07_RS25435 () | 81770..82117 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| FH07_RS25440 () | 82111..82950 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| FH07_RS25445 () | 83078..83281 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| FH07_RS25450 () | 83437..84642 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| FH07_RS25455 () | 84653..84957 | + | 305 | Protein_100 | helix-turn-helix transcriptional regulator | - |
| FH07_RS28910 () | 85001..85066 | + | 66 | Protein_101 | EAL domain-containing protein | - |
| FH07_RS25460 () | 85184..85948 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| FH07_RS25470 () | 86441..87025 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| FH07_RS25475 () | 87025..88263 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| FH07_RS25480 () | 88260..89165 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| FH07_RS25490 () | 89325..90022 | + | 698 | Protein_106 | IS1 family transposase IS1R | Transposase |
| FH07_RS27380 () | 90019..90282 | + | 264 | WP_049802299.1 | antibiotic biosynthesis monooxygenase | - |
| FH07_RS25495 () | 90275..90661 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| FH07_RS25500 () | 90669..91355 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| FH07_RS25505 () | 91333..91956 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| FH07_RS25510 () | 92038..93243 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| FH07_RS25515 () | 93356..93949 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| FH07_RS25520 () | 94108..94719 | - | 612 | Protein_113 | IS1 family transposase | - |
| FH07_RS29040 () | 94919..95032 | + | 114 | Protein_114 | IS6 family transposase | - |
| FH07_RS25530 () | 95182..95340 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| FH07_RS25535 () | 95330..95836 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| FH07_RS25540 () | 96019..96834 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| FH07_RS25545 () | 97181..99067 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| FH07_RS25550 () | 99108..99635 | + | 528 | WP_000178050.1 | iron transporter | - |
| FH07_RS25555 () | 99739..101118 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| FH07_RS25560 () | 101121..102404 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| FH07_RS25565 () | 102394..103524 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| FH07_RS25570 () | 103529..104224 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| FH07_RS25575 () | 104211..104696 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| FH07_RS25580 () | 104721..105206 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| FH07_RS25585 () | 105328..105858 | + | 531 | Protein_126 | histidine-type phosphatase | - |
| FH07_RS25590 () | 105917..106621 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| FH07_RS25595 () | 106690..108375 | - | 1686 | Protein_128 | Multifunctional conjugation protein TraI | Relaxase |
| FH07_RS25600 () | 108375..110564 | - | 2190 | WP_024946705.1 | type IV conjugative transfer system coupling protein TraD | - |
| FH07_RS25605 () | 110561..111340 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| FH07_RS25610 () | 111543..112274 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| FH07_RS25615 () | 112306..112803 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| FH07_RS25620 () | 112822..115641 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| FH07_RS25625 () | 115638..117011 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| FH07_RS25630 () | 116998..117423 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| FH07_RS25635 () | 117371..117718 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| FH07_RS25640 () | 117648..118193 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FH07_RS25645 () | 118180..118464 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FH07_RS25650 () | 118591..118911 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| FH07_RS25655 () | 118959..119656 | - | 698 | Protein_140 | IS1 family transposase IS1G | Transposase |
| FH07_RS25660 () | 119771..120373 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|