MGE detailed information
MGE type: Conjugative plasmid MGE length: 98067 bp
Accession: NZ_CP007135 Location: 1..98067 Organism: Escherichia coli O145:H28 str. RM12761 Replicon: plasmid pO145-12761
Accession: NZ_CP007135 Location: 1..98067 Organism: Escherichia coli O145:H28 str. RM12761 Replicon: plasmid pO145-12761
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECRM12761_RS27810 () | 41..2701 | + | 2661 | WP_000770131.1 | Metalloprotease StcE | VF |
| ECRM12761_RS27815 () | 2785..3660 | + | 876 | WP_001368871.1 | Type II secretion system protein C | VF |
| ECRM12761_RS27820 () | 3661..5631 | + | 1971 | WP_013009342.1 | Type II secretion system protein D | VF |
| ECRM12761_RS27825 () | 5628..7130 | + | 1503 | WP_001418198.1 | Type II secretion system protein E | VF |
| ECRM12761_RS27830 () | 7132..8355 | + | 1224 | WP_001173149.1 | Type II secretion system protein F | VF |
| ECRM12761_RS27835 () | 8386..8820 | + | 435 | WP_001231213.1 | Type II secretion system protein G | VF |
| ECRM12761_RS27840 () | 8817..9368 | + | 552 | WP_000082928.1 | type II secretion system minor pseudopilin GspH | - |
| ECRM12761_RS27845 () | 9383..9730 | + | 348 | WP_001420206.1 | Type II secretion system protein I | VF |
| ECRM12761_RS27850 () | 9727..10326 | + | 600 | WP_000082784.1 | Type II secretion system protein J | VF |
| ECRM12761_RS27855 () | 10323..11300 | + | 978 | WP_000842183.1 | Putative type II secretion system protein K | VF |
| ECRM12761_RS27860 () | 11339..12511 | + | 1173 | WP_071526091.1 | Type II secretion system protein L | VF |
| ECRM12761_RS27865 () | 12498..13010 | + | 513 | WP_025380709.1 | Type II secretion system protein M | VF |
| ECRM12761_RS27880 () | 13031..14244 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
| ECRM12761_RS27885 () | 14326..15159 | + | 834 | WP_025380710.1 | Type 4 prepilin-like proteins leader peptide-processing enzyme | VF |
| ECRM12761_RS27890 () | 15253..15654 | + | 402 | WP_001222320.1 | GspS family T2SS pilot lipoprotein variant EptO | - |
| ECRM12761_RS31885 () | 15729..15944 | + | 216 | Protein_15 | IS3 family transposase IS1203 | Transposase |
| ECRM12761_RS32860 () | 16243..16536 | + | 294 | Protein_16 | hypothetical protein | - |
| ECRM12761_RS27905 () | 16765..17013 | + | 249 | WP_000083841.1 | replication regulatory protein RepA | - |
| ECRM12761_RS33050 () | 17036..17143 | + | 108 | Protein_18 | incFII family plasmid replication initiator RepA | - |
| ECRM12761_RS27915 () | 18099..18349 | + | 251 | Protein_19 | antitoxin | - |
| ECRM12761_RS27920 () | 18346..18633 | + | 288 | WP_000222761.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ECRM12761_RS27925 () | 18737..19327 | + | 591 | WP_000594717.1 | Serine acetyltransferase | VF |
| ECRM12761_RS28545 () | 19431..20047 | + | 617 | Protein_22 | hypothetical protein | - |
| ECRM12761_RS27935 () | 20072..20365 | + | 294 | WP_000633741.1 | hypothetical protein | - |
| ECRM12761_RS27940 () | 20574..20705 | - | 132 | WP_106898824.1 | Serine protease EspP | VF |
| ECRM12761_RS27945 () | 20914..21523 | + | 610 | Protein_25 | Tn3 family transposase TnpR_ISMpo10 | Transposase |
| ECRM12761_RS27950 () | 21504..22190 | + | 687 | Protein_26 | Tn3 family transposase TnpA_ISPa40 | Transposase |
| ECRM12761_RS27955 () | 22349..22645 | + | 297 | WP_000766060.1 | hypothetical protein | - |
| ECRM12761_RS27960 () | 22645..23832 | + | 1188 | WP_025380712.1 | IS91 family transposase ISEc37 | Transposase |
| ECRM12761_RS30945 () | 24021..24173 | - | 153 | Protein_29 | IS3 family transposase IS1203 | Transposase |
| ECRM12761_RS27970 () | 25161..25382 | + | 222 | WP_000907893.1 | hypothetical protein | - |
| ECRM12761_RS27975 () | 25649..26470 | + | 822 | WP_001302199.1 | polysaccharide deacetylase family protein | - |
| ECRM12761_RS27980 () | 26470..27576 | + | 1107 | WP_000975743.1 | glycosyltransferase family 4 protein | - |
| ECRM12761_RS27985 () | 27670..29391 | + | 1722 | WP_000550559.1 | phosphoethanolamine transferase CptA | - |
| ECRM12761_RS27990 () | 29465..30463 | + | 999 | WP_077629919.1 | Lipid A biosynthesis myristoyltransferase | VF |
| ECRM12761_RS32705 () | 30516..30704 | + | 189 | Protein_35 | hypothetical protein | - |
| ECRM12761_RS28000 () | 30767..32306 | - | 1540 | Protein_36 | IS66 family transposase ISEc8 | Transposase |
| ECRM12761_RS28005 () | 32356..32703 | - | 348 | WP_000612632.1 | IS66 family transposase ISEc8 | Transposase |
| ECRM12761_RS28010 () | 32700..33080 | - | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| ECRM12761_RS28015 () | 33243..33668 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| ECRM12761_RS28020 () | 33665..34015 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| ECRM12761_RS28025 () | 34046..35659 | + | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| ECRM12761_RS28030 () | 35770..36330 | - | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| ECRM12761_RS28035 () | 36433..37293 | - | 861 | WP_000704529.1 | putative protein YcjY | VF |
| ECRM12761_RS28040 () | 37352..38098 | - | 747 | WP_000205715.1 | conjugal transfer pilus acetylase TraX | - |
| ECRM12761_RS28045 () | 38118..43388 | - | 5271 | WP_025380714.1 | Multifunctional conjugation protein TraI | Relaxase |
| ECRM12761_RS28050 () | 43388..45541 | - | 2154 | WP_001369365.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECRM12761_RS28055 () | 45793..46524 | - | 732 | WP_000782454.1 | complement resistance protein TraT | - |
| ECRM12761_RS28060 () | 46573..47058 | - | 486 | WP_000605868.1 | hypothetical protein | - |
| ECRM12761_RS28065 () | 47074..49635 | - | 2562 | Protein_49 | conjugal transfer mating pair stabilization protein TraG | - |
| ECRM12761_RS28075 () | 49685..50898 | + | 1214 | WP_136952279.1 | IS3 family transposase IS629 | Transposase |
| ECRM12761_RS33055 () | 50945..51214 | - | 270 | Protein_51 | hypothetical protein | - |
| ECRM12761_RS30970 () | 51207..51428 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| ECRM12761_RS28085 () | 51563..52078 | - | 516 | WP_021532964.1 | type IV conjugative transfer system lipoprotein TraV | - |
| ECRM12761_RS28090 () | 52075..52326 | - | 252 | WP_001038348.1 | conjugal transfer protein TrbG | - |
| ECRM12761_RS28095 () | 52319..52672 | - | 354 | WP_071826576.1 | DUF2689 domain-containing protein | - |
| ECRM12761_RS28100 () | 52626..53213 | - | 588 | WP_025380716.1 | conjugal transfer protein TraP | - |
| ECRM12761_RS28105 () | 53203..54630 | - | 1428 | WP_025380717.1 | conjugal transfer protein TraB | - |
| ECRM12761_RS28110 () | 54630..55334 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| ECRM12761_RS28115 () | 55345..55911 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| ECRM12761_RS28120 () | 55933..56244 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| ECRM12761_RS28125 () | 56259..56618 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| ECRM12761_RS28130 () | 56652..56879 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| ECRM12761_RS28135 () | 56974..57660 | - | 687 | WP_025380718.1 | PAS domain-containing protein | - |
| ECRM12761_RS28140 () | 57851..58234 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| ECRM12761_RS28145 () | 58511..59158 | + | 648 | WP_122994606.1 | hypothetical protein | VF |
| ECRM12761_RS28150 () | 59455..60276 | - | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| ECRM12761_RS28155 () | 60394..60681 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| ECRM12761_RS28170 () | 61603..61761 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 61805..62029 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 61805..62029 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 61805..62029 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 61805..62029 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| ECRM12761_RS32820 () | 61841..62029 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| ECRM12761_RS28180 () | 62041..62760 | - | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| ECRM12761_RS28185 () | 62757..63191 | - | 435 | WP_025380720.1 | conjugation system SOS inhibitor PsiB | - |
| ECRM12761_RS30980 () | 63246..63443 | - | 198 | Protein_72 | hypothetical protein | - |
| ECRM12761_RS28190 () | 63471..63704 | - | 234 | WP_025380721.1 | DUF905 family protein | - |
| ECRM12761_RS28195 () | 63767..64306 | - | 540 | WP_025380722.1 | single-stranded DNA-binding protein | - |
| ECRM12761_RS33060 () | 64332..64538 | - | 207 | WP_000547944.1 | hypothetical protein | - |
| ECRM12761_RS28205 () | 65147..65338 | - | 192 | WP_001027500.1 | hypothetical protein | - |
| ECRM12761_RS28210 () | 65335..65799 | - | 465 | WP_044697612.1 | DUF1380 family protein | - |
| ECRM12761_RS28215 () | 65799..66101 | - | 303 | WP_072128865.1 | antirestriction protein | - |
| ECRM12761_RS33065 () | 66642..66959 | - | 318 | Protein_79 | hypothetical protein | - |
| ECRM12761_RS33070 () | 66952..67038 | - | 87 | Protein_80 | adenine-specific DNA-methyltransferase | - |
| ECRM12761_RS31905 () | 67115..67420 | - | 306 | WP_033810170.1 | hypothetical protein | - |
| ECRM12761_RS32825 () | 67424..67840 | - | 417 | Protein_82 | DUF1281 domain-containing protein | - |
| ECRM12761_RS28235 () | 67721..68534 | + | 814 | Protein_83 | hypothetical protein | - |
| ECRM12761_RS28240 () | 68602..68967 | + | 366 | WP_000091308.1 | hypothetical protein | - |
| ECRM12761_RS28245 () | 68967..70154 | + | 1188 | WP_025380712.1 | IS91 family transposase ISEc37 | Transposase |
| ECRM12761_RS28250 () | 70367..70546 | - | 180 | WP_000526859.1 | hypothetical protein | VF |
| ECRM12761_RS28255 () | 70749..71123 | + | 375 | WP_001368887.1 | hypothetical protein | - |
| ECRM12761_RS32730 () | 71434..71595 | - | 162 | Protein_88 | epoxyqueuosine reductase QueH | - |
| ECRM12761_RS28680 () | 71646..71786 | + | 141 | Protein_89 | serine/threonine protein kinase | - |
| ECRM12761_RS28265 () | 71910..72650 | + | 741 | WP_001066926.1 | IS91 family transposase ISMno23 | Transposase |
| ECRM12761_RS28280 () | 74195..75172 | - | 978 | WP_000361617.1 | RepB family plasmid replication initiator protein | - |
| ECRM12761_RS32735 () | 75818..76106 | - | 289 | Protein_93 | integrase core domain-containing protein | - |
| ECRM12761_RS28290 () | 76291..77478 | - | 1188 | WP_025380712.1 | IS91 family transposase ISEc37 | Transposase |
| ECRM12761_RS28295 () | 77478..77843 | - | 366 | WP_000091308.1 | hypothetical protein | - |
| ECRM12761_RS33075 () | 77929..78051 | - | 123 | Protein_96 | IS3 family transposase | - |
| ECRM12761_RS28300 () | 78053..78340 | - | 288 | WP_001270421.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| ECRM12761_RS28305 () | 78337..78588 | - | 252 | WP_001132893.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| ECRM12761_RS32830 () | 78762..79079 | - | 318 | WP_157910106.1 | hypothetical protein | - |
| ECRM12761_RS28315 () | 79306..80511 | + | 1206 | WP_000817642.1 | Plasmid partition protein A | VF |
| ECRM12761_RS28320 () | 80508..81470 | + | 963 | WP_000756329.1 | ParB/RepB/Spo0J family partition protein | - |
| ECRM12761_RS28325 () | 81610..81978 | - | 369 | Protein_102 | DUF4113 domain-containing protein | - |
| ECRM12761_RS28330 () | 82166..83353 | - | 1188 | WP_025380712.1 | IS91 family transposase ISEc37 | Transposase |
| ECRM12761_RS28335 () | 83353..83718 | - | 366 | WP_000091308.1 | hypothetical protein | - |
| ECRM12761_RS28345 () | 83809..84305 | + | 497 | Protein_105 | IS3 family transposase IS629 | Transposase |
| ECRM12761_RS28350 () | 84828..85343 | + | 516 | WP_000839950.1 | Hemolysin-activating lysine-acyltransferase HlyC | VF |
| ECRM12761_RS28355 () | 85345..88341 | + | 2997 | WP_000217745.1 | Hemolysin, chromosomal | VF |
| ECRM12761_RS28360 () | 88391..90511 | + | 2121 | WP_000987096.1 | Alpha-hemolysin translocation ATP-binding protein HlyB | VF |
| ECRM12761_RS28365 () | 90515..91954 | + | 1440 | WP_001213545.1 | Hemolysin secretion protein D, chromosomal | VF |
| ECRM12761_RS32745 () | 92021..92188 | + | 168 | Protein_110 | hypothetical protein | - |
| ECRM12761_RS28370 () | 92202..92855 | - | 654 | Protein_111 | IS3 family transposase ISEc48 | Transposase |
| ECRM12761_RS28375 () | 92894..94432 | - | 1539 | WP_025380726.1 | IS66 family transposase ISEc8 | Transposase |
| ECRM12761_RS28380 () | 94482..94829 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| ECRM12761_RS28385 () | 94826..95206 | - | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| ECRM12761_RS28390 () | 95367..95579 | + | 213 | WP_032257629.1 | ANR family transcriptional regulator | - |
| ECRM12761_RS28395 () | 95825..96219 | + | 395 | Protein_116 | thermonuclease family protein | - |
| ECRM12761_RS32750 () | 96582..96725 | - | 144 | Protein_117 | IS3 family transposase | - |
| ECRM12761_RS28400 () | 96728..96871 | - | 144 | Protein_118 | IS3 family transposase IS911 | Transposase |
| ECRM12761_RS31055 () | 96948..97621 | + | 674 | Protein_119 | DDE-type integrase/transposase/recombinase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|