MGE detailed information
MGE type: Conjugative plasmid MGE length: 94613 bp
Accession: NZ_AP023236 Location: 1..94613 Organism: Escherichia coli strain YJ6 Replicon: plasmid pYJ6-NDM5
Accession: NZ_AP023236 Location: 1..94613 Organism: Escherichia coli strain YJ6 Replicon: plasmid pYJ6-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HXS64_RS22355 () | 1..255 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| HXS64_RS22360 () | 493..567 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| HXS64_RS22365 () | 560..1417 | + | 858 | WP_060591631.1 | incFII family plasmid replication initiator RepA | - |
| HXS64_RS22370 () | 2356..3009 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HXS64_RS22375 () | 3102..3359 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HXS64_RS22380 () | 3292..3693 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HXS64_RS22385 () | 3942..4357 | + | 416 | Protein_6 | IS1 family transposase IS1R | Transposase |
| HXS64_RS22390 () | 4393..4938 | - | 546 | Protein_7 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HXS64_RS22395 () | 5004..5708 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HXS64_RS22400 () | 5720..7201 | - | 1482 | WP_024210412.1 | IS91 family transposase ISVsa3 | Transposase |
| HXS64_RS22405 () | 7428..7769 | - | 342 | WP_023909256.1 | 60 kDa chaperonin 2 | VF |
| HXS64_RS22410 () | 7730..8179 | - | 450 | WP_013362817.1 | hypothetical protein | - |
| HXS64_RS22415 () | 8694..8864 | - | 171 | WP_170852050.1 | rRNA adenine methyltransferase | - |
| HXS64_RS22420 () | 8809..9546 | - | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| HXS64_RS22425 () | 9672..9767 | - | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| HXS64_RS22430 () | 9902..10606 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HXS64_RS22435 () | 10728..11642 | + | 915 | WP_023063803.1 | hypothetical protein | ARG |
| HXS64_RS22440 () | 11639..12877 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| HXS64_RS22445 () | 12877..13461 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| HXS64_RS22450 () | 13649..14413 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| HXS64_RS22455 () | 14715..15272 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HXS64_RS22460 () | 15455..16315 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HXS64_RS22465 () | 16485..17240 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| HXS64_RS22470 () | 17321..17869 | - | 549 | WP_014342204.1 | cation:proton antiporter | - |
| HXS64_RS22475 () | 17932..18282 | + | 351 | Protein_24 | 60 kDa chaperonin | VF |
| HXS64_RS22480 () | 18476..18691 | - | 216 | Protein_25 | IS6 family transposase IS26 | Transposase |
| HXS64_RS22485 () | 18743..19447 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HXS64_RS22490 () | 19612..19905 | + | 294 | Protein_27 | IS30 family transposase | - |
| HXS64_RS22495 () | 20006..20818 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| HXS64_RS22500 () | 20822..21187 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| HXS64_RS22505 () | 21192..21830 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| HXS64_RS22510 () | 21841..22872 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| HXS64_RS22515 () | 23185..24726 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| HXS64_RS22520 () | 25131..25970 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| HXS64_RS22525 () | 25964..26311 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| HXS64_RS22530 () | 26475..27266 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HXS64_RS22535 () | 27272..27562 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HXS64_RS22540 () | 27674..28171 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HXS64_RS22545 () | 28316..29182 | + | 867 | Protein_38 | IS91 family transposase ISAzo26 | Transposase |
| HXS64_RS22550 () | 29237..29941 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HXS64_RS22555 () | 30007..31521 | + | 1515 | Protein_40 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HXS64_RS22560 () | 31590..32474 | + | 885 | WP_001345827.1 | hypothetical protein | - |
| HXS64_RS22565 () | 32470..32639 | + | 170 | Protein_42 | resolvase | - |
| HXS64_RS22570 () | 32646..32813 | - | 168 | WP_001430249.1 | hypothetical protein | - |
| HXS64_RS22575 () | 32985..35660 | - | 2676 | WP_015059139.1 | hypothetical protein | - |
| HXS64_RS22580 () | 35963..36964 | + | 1002 | WP_000138753.1 | DUF4238 domain-containing protein | - |
| HXS64_RS22585 () | 37189..37651 | - | 463 | Protein_46 | hypothetical protein | - |
| HXS64_RS22590 () | 37760..38110 | - | 351 | WP_001430247.1 | plasmid partitioning/stability family protein | - |
| HXS64_RS22595 () | 38113..39075 | - | 963 | WP_000959875.1 | plasmid segregation protein ParM | - |
| HXS64_RS22600 () | 39207..39515 | + | 309 | WP_039021875.1 | hypothetical protein | - |
| HXS64_RS22605 () | 39592..40275 | + | 684 | WP_000085889.1 | DNA methylase | - |
| HXS64_RS22610 () | 40276..40497 | + | 222 | WP_001104902.1 | hypothetical protein | - |
| HXS64_RS22615 () | 40510..40944 | + | 435 | WP_000274504.1 | DUF1380 family protein | - |
| HXS64_RS22620 () | 40989..41759 | + | 771 | WP_001006207.1 | hypothetical protein | - |
| HXS64_RS22625 () | 42242..42544 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| HXS64_RS22630 () | 42591..43013 | + | 423 | WP_000271684.1 | DUF1380 family protein | - |
| HXS64_RS22635 () | 43010..43201 | + | 192 | WP_039021874.1 | hypothetical protein | - |
| HXS64_RS22640 () | 43515..45182 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| HXS64_RS22645 () | 46582..46812 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| HXS64_RS22650 () | 46864..48225 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| HXS64_RS22655 () | 48272..48835 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| HXS64_RS22665 () | 49684..50211 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| HXS64_RS22670 () | 50269..50502 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| HXS64_RS22675 () | 50563..52586 | + | 2024 | Protein_63 | ParB/RepB/Spo0J family partition protein | - |
| HXS64_RS22680 () | 52655..53089 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HXS64_RS22685 () | 53086..53805 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 53817..54041 | + | 225 | NuclAT_0 | - | - |
| - () | 53817..54041 | + | 225 | NuclAT_0 | - | - |
| - () | 53817..54041 | + | 225 | NuclAT_0 | - | - |
| - () | 53817..54041 | + | 225 | NuclAT_0 | - | - |
| HXS64_RS22690 () | 53826..54005 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - () | 53974..54039 | + | 66 | - | - | Antitoxin Detail |
| HXS64_RS22695 () | 54085..54243 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HXS64_RS22700 () | 54481..54858 | - | 378 | Protein_68 | hypothetical protein | - |
| HXS64_RS22705 () | 55158..55454 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| HXS64_RS22710 () | 55565..56386 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| HXS64_RS22715 () | 56683..57285 | - | 603 | WP_000243713.1 | hypothetical protein | VF |
| HXS64_RS22720 () | 57608..57991 | + | 384 | WP_001354030.1 | relaxosome protein TraM | - |
| HXS64_RS22725 () | 58185..58856 | + | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| HXS64_RS22730 () | 58993..59220 | + | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| HXS64_RS22735 () | 59253..59612 | + | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
| HXS64_RS22740 () | 59627..59938 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| HXS64_RS22745 () | 59960..60526 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| HXS64_RS22750 () | 60513..61241 | + | 729 | WP_001230772.1 | type-F conjugative transfer system secretin TraK | - |
| HXS64_RS22755 () | 61241..62692 | + | 1452 | WP_000146675.1 | conjugal transfer protein TraB | - |
| HXS64_RS22760 () | 62661..63248 | + | 588 | WP_001444176.1 | conjugal transfer protein TraP | - |
| HXS64_RS22765 () | 63187..63555 | + | 369 | WP_001315561.1 | conjugal transfer protein TrbD | - |
| HXS64_RS22770 () | 63552..64067 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HXS64_RS22775 () | 64202..64423 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| HXS64_RS22780 () | 64416..64892 | + | 477 | WP_000549587.1 | hypothetical protein | - |
| HXS64_RS22785 () | 64972..65190 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| HXS64_RS22790 () | 65218..65565 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| HXS64_RS22795 () | 65691..68321 | + | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| HXS64_RS22800 () | 68318..68704 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| HXS64_RS22805 () | 68701..69333 | + | 633 | WP_001203728.1 | type-F conjugative transfer system protein TraW | - |
| HXS64_RS22810 () | 69330..70322 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| HXS64_RS22815 () | 70352..70657 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| HXS64_RS22820 () | 70666..71304 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HXS64_RS22825 () | 71301..73151 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HXS64_RS22830 () | 73178..73435 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| HXS64_RS22835 () | 73428..74171 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HXS64_RS22840 () | 74185..74529 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| HXS64_RS22845 () | 74648..74932 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HXS64_RS22850 () | 74919..75464 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HXS64_RS22855 () | 75394..75741 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| HXS64_RS22860 () | 75689..76114 | + | 426 | WP_001444237.1 | F-type conjugal transfer protein TrbF | - |
| HXS64_RS22865 () | 76101..77474 | + | 1374 | WP_000944331.1 | conjugal transfer protein TraH | - |
| HXS64_RS22870 () | 77471..80293 | + | 2823 | WP_001007039.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HXS64_RS22875 () | 80309..80794 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| HXS64_RS22880 () | 80843..81574 | + | 732 | WP_000782451.1 | complement resistance protein TraT | - |
| HXS64_RS22885 () | 81777..82514 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| HXS64_RS22890 () | 82565..84826 | + | 2262 | WP_046072940.1 | type IV conjugative transfer system coupling protein TraD | - |
| HXS64_RS22895 () | 84826..90096 | + | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| HXS64_RS22900 () | 90116..90862 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| HXS64_RS22905 () | 90921..91781 | + | 861 | WP_000704523.1 | putative protein YcjY | VF |
| HXS64_RS22910 () | 91884..92444 | + | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| HXS64_RS22915 () | 92573..92785 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| HXS64_RS22950 () | 93030..93491 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| HXS64_RS22925 () | 93537..93746 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| HXS64_RS22930 () | 93784..94374 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|