MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 108281 bp
Accession: NZ_AP023225 Location: 1..108281 Organism: Escherichia coli strain YJ1 Replicon: plasmid pYJ1-NDM5
Accession: NZ_AP023225 Location: 1..108281 Organism: Escherichia coli strain YJ1 Replicon: plasmid pYJ1-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HXS59_RS23245 () | 217..858 | - | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| HXS59_RS23250 () | 1098..1418 | - | 321 | Protein_1 | IS1380 family transposase ISEcp1 | Transposase |
| HXS59_RS23255 () | 1431..1991 | + | 561 | WP_000147567.1 | recombinase family protein | - |
| HXS59_RS23260 () | 1994..4465 | + | 2472 | Protein_3 | Tn3-like element TnAs3 family transposase | - |
| HXS59_RS23265 () | 4612..5471 | - | 860 | Protein_4 | Beta-lactamase TEM-12 | ARG |
| HXS59_RS23270 () | 5654..5992 | - | 339 | Protein_5 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HXS59_RS23275 () | 6056..6760 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HXS59_RS23280 () | 7142..8017 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| HXS59_RS23285 () | 8064..8396 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| HXS59_RS23290 () | 8410..10653 | + | 2244 | Protein_9 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HXS59_RS23295 () | 10718..11422 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HXS59_RS23300 () | 11476..11916 | - | 441 | Protein_11 | CatB-related O-acetyltransferase | - |
| HXS59_RS23305 () | 12054..12884 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| HXS59_RS23310 () | 13015..13569 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| HXS59_RS23315 () | 13713..14417 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HXS59_RS23320 () | 14480..16825 | + | 2346 | Protein_15 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| HXS59_RS23325 () | 16962..17363 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HXS59_RS23330 () | 17296..17553 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HXS59_RS23335 () | 17646..18299 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HXS59_RS23340 () | 19239..20096 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| HXS59_RS23345 () | 20089..20163 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| HXS59_RS23910 () | 20160..20294 | - | 135 | Protein_21 | protein CopA/IncA | - |
| HXS59_RS23350 () | 20525..22069 | + | 1545 | WP_176486343.1 | IS21 family transposase ISEc12 | Transposase |
| HXS59_RS23355 () | 22084..22830 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| HXS59_RS23360 () | 22990..23244 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| HXS59_RS23365 () | 23541..23675 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 23720..23780 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 23720..23780 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 23720..23780 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 23720..23780 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| HXS59_RS23370 () | 23747..24033 | - | 287 | Protein_26 | DUF2726 domain-containing protein | - |
| HXS59_RS23375 () | 24546..24758 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| HXS59_RS23380 () | 24889..25449 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| HXS59_RS23385 () | 25504..26250 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| HXS59_RS23390 () | 26270..28663 | - | 2394 | Protein_30 | Multifunctional conjugation protein TraI | Relaxase |
| HXS59_RS23395 () | 28633..29715 | - | 1083 | WP_060621339.1 | DUF3560 domain-containing protein | - |
| HXS59_RS23400 () | 29767..29997 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| HXS59_RS23405 () | 31032..31223 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| HXS59_RS23410 () | 31220..31360 | - | 141 | WP_162752839.1 | hypothetical protein | - |
| HXS59_RS23415 () | 31360..31641 | - | 282 | WP_136512299.1 | DUF1380 family protein | - |
| HXS59_RS23420 () | 31688..31990 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| HXS59_RS23425 () | 32530..33306 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| HXS59_RS23430 () | 33357..33791 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| HXS59_RS23435 () | 33805..34026 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| HXS59_RS23440 () | 34027..34710 | - | 684 | WP_000086185.1 | DNA methylase | - |
| HXS59_RS23445 () | 34787..35091 | - | 305 | Protein_41 | hypothetical protein | - |
| HXS59_RS23450 () | 35095..35997 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HXS59_RS23455 () | 36864..37835 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HXS59_RS23460 () | 37835..39001 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| HXS59_RS23465 () | 39589..40344 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| HXS59_RS23470 () | 41118..41924 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| HXS59_RS23475 () | 41925..42230 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| HXS59_RS23480 () | 42232..42450 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| HXS59_RS23485 () | 43084..43281 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| HXS59_RS23490 () | 43278..43562 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| HXS59_RS23495 () | 43582..44715 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| HXS59_RS23500 () | 44978..48097 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| HXS59_RS23505 () | 48404..48634 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| HXS59_RS23510 () | 48631..49047 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HXS59_RS23515 () | 49209..51347 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| HXS59_RS23520 () | 51812..52807 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| HXS59_RS23525 () | 52811..53743 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| HXS59_RS23530 () | 53880..54577 | - | 698 | Protein_58 | IS1 family transposase IS1G | Transposase |
| HXS59_RS23535 () | 54791..57907 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| HXS59_RS23540 () | 58029..59312 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| HXS59_RS23545 () | 59309..60865 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| HXS59_RS23550 () | 61048..61269 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HXS59_RS23555 () | 61269..61649 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| HXS59_RS23560 () | 61654..61833 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| HXS59_RS23565 () | 61861..62220 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| HXS59_RS23570 () | 62144..62557 | + | 414 | Protein_66 | IS3 family transposase ISLad1 | Transposase |
| HXS59_RS23575 () | 63353..64330 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| HXS59_RS23580 () | 64615..65355 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| HXS59_RS23585 () | 65476..65658 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| HXS59_RS23590 () | 66001..66308 | - | 308 | Protein_70 | type II toxin-antitoxin system ParD family antitoxin | - |
| HXS59_RS23595 () | 66801..67673 | + | 873 | WP_104989445.1 | hypothetical protein | - |
| HXS59_RS23600 () | 67707..68404 | + | 698 | Protein_72 | IS1 family transposase IS1R | Transposase |
| HXS59_RS23605 () | 68420..68539 | + | 120 | Protein_73 | ArsR family transcriptional regulator | - |
| HXS59_RS23610 () | 68517..69140 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| HXS59_RS23615 () | 69222..70427 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| HXS59_RS23620 () | 70540..71133 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| HXS59_RS23625 () | 71267..71971 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| HXS59_RS23630 () | 72025..72390 | - | 366 | Protein_78 | chromate transporter | - |
| HXS59_RS23635 () | 72546..72749 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| HXS59_RS23640 () | 72877..73716 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| HXS59_RS23645 () | 73710..74057 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| HXS59_RS23650 () | 74221..75012 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HXS59_RS23655 () | 75018..75308 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HXS59_RS23660 () | 75420..75917 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HXS59_RS23665 () | 76062..76928 | + | 867 | Protein_85 | class 1 integron integrase IntI1 | - |
| HXS59_RS23670 () | 76983..77687 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HXS59_RS23675 () | 77852..78145 | + | 294 | Protein_87 | IS30 family transposase ISAba125 | Transposase |
| HXS59_RS23680 () | 78246..79058 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| HXS59_RS23685 () | 79062..79427 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| HXS59_RS23690 () | 79432..80070 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| HXS59_RS23695 () | 80081..81112 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| HXS59_RS23700 () | 81425..82966 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| HXS59_RS23705 () | 83371..84209 | - | 839 | Protein_93 | Dihydropteroate synthase | ARG |
| HXS59_RS23710 () | 84203..84550 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| HXS59_RS23715 () | 84756..85544 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HXS59_RS23720 () | 85675..86148 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| HXS59_RS23725 () | 86306..87319 | + | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| HXS59_RS23730 () | 87522..87668 | + | 147 | Protein_98 | EAL domain-containing protein | - |
| HXS59_RS23735 () | 87721..88425 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HXS59_RS23740 () | 88584..88865 | - | 282 | Protein_100 | transposase zinc-binding domain-containing protein | - |
| HXS59_RS23745 () | 89012..89872 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HXS59_RS23750 () | 90055..90246 | - | 192 | Protein_102 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HXS59_RS23755 () | 90310..91014 | + | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HXS59_RS23760 () | 91069..91914 | - | 846 | Protein_104 | IS4 family transposase IS10R | Transposase |
| HXS59_RS23765 () | 92024..92986 | - | 963 | Protein_105 | IS4 family transposase IS10R | Transposase |
| HXS59_RS23770 () | 93129..93989 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| HXS59_RS23775 () | 94002..94544 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| HXS59_RS23780 () | 95026..95217 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| HXS59_RS23785 () | 95241..95468 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| HXS59_RS23790 () | 95519..96646 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| HXS59_RS23795 () | 96683..97387 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HXS59_RS23800 () | 97509..98423 | + | 915 | WP_023063803.1 | hypothetical protein | ARG |
| HXS59_RS23805 () | 98420..99658 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| HXS59_RS23810 () | 99658..100242 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| HXS59_RS23815 () | 100735..101499 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| HXS59_RS23820 () | 101639..102343 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HXS59_RS23825 () | 102404..103240 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| HXS59_RS23830 () | 103240..104043 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HXS59_RS23835 () | 104104..104919 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| HXS59_RS23840 () | 105227..106078 | - | 852 | WP_000240536.1 | replication protein | - |
| HXS59_RS23845 () | 106065..106784 | - | 720 | Protein_121 | AAA family ATPase | - |
| HXS59_RS23850 () | 106834..107538 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HXS59_RS23855 () | 107602..108273 | + | 672 | Protein_123 | Tn3 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|