MGE detailed information
MGE type: Conjugative plasmid MGE length: 115013 bp
Accession: NZ_AP023199 Location: 1..115013 Organism: Escherichia coli strain TUM18780 Replicon: plasmid pMTY18780-2
Accession: NZ_AP023199 Location: 1..115013 Organism: Escherichia coli strain TUM18780 Replicon: plasmid pMTY18780-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUV22_RS24480 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| HUV22_RS24485 () | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| HUV22_RS24490 () | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| HUV22_RS24495 () | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| HUV22_RS24500 () | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| HUV22_RS24505 () | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| HUV22_RS24510 () | 7653..9194 | + | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| HUV22_RS24515 () | 9209..9955 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| HUV22_RS24520 () | 10009..10170 | - | 162 | WP_174402698.1 | integrase core domain-containing protein | - |
| HUV22_RS24525 () | 10354..11567 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| HUV22_RS24530 () | 11715..11983 | - | 269 | Protein_10 | IS3 family transposase ISLad1 | Transposase |
| HUV22_RS24535 () | 12040..12737 | + | 698 | Protein_11 | IS1 family transposase | - |
| HUV22_RS24540 () | 12748..12951 | - | 204 | WP_001259759.1 | colicin V family bacteriocin | - |
| HUV22_RS24545 () | 12929..13165 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| HUV22_RS24550 () | 13629..13910 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| HUV22_RS24555 () | 14083..14250 | + | 168 | Protein_15 | colicin-B | - |
| HUV22_RS24560 () | 14268..14795 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| HUV22_RS24565 () | 15039..15854 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| HUV22_RS24570 () | 15904..16257 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| HUV22_RS24580 () | 16435..17226 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| HUV22_RS24585 () | 17223..17912 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| HUV22_RS24590 () | 17956..18306 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| HUV22_RS24595 () | 18851..19939 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| HUV22_RS24600 () | 19941..22166 | + | 2226 | WP_000698737.1 | phage T7 exclusion protein | - |
| HUV22_RS24605 () | 22216..23115 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| HUV22_RS24610 () | 23105..23395 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| HUV22_RS24615 () | 23691..23921 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| HUV22_RS24620 () | 23918..24334 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HUV22_RS24625 () | 24496..26634 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| HUV22_RS24630 () | 26988..27245 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| HUV22_RS24635 () | 27245..27835 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| HUV22_RS24640 () | 28098..29654 | + | 1557 | Protein_31 | AAA family ATPase | - |
| HUV22_RS24645 () | 29846..30463 | + | 618 | WP_000521603.1 | hypothetical protein | - |
| HUV22_RS24650 () | 30756..31835 | - | 1080 | WP_001089727.1 | permease | - |
| HUV22_RS24655 () | 31940..32263 | + | 324 | WP_001175594.1 | helix-turn-helix domain-containing protein | - |
| HUV22_RS24660 () | 32364..32744 | + | 381 | Protein_35 | NAD(P)H-dependent oxidoreductase | - |
| HUV22_RS24665 () | 32797..33501 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUV22_RS24670 () | 33567..35081 | + | 1515 | Protein_37 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUV22_RS24675 () | 35139..35381 | + | 243 | WP_000844627.1 | transposase | - |
| HUV22_RS24680 () | 35413..36048 | - | 636 | WP_039045916.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HUV22_RS24685 () | 36154..37353 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| HUV22_RS24690 () | 37385..38269 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| HUV22_RS24695 () | 38407..38814 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| HUV22_RS24700 () | 38806..40479 | + | 1674 | Protein_43 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUV22_RS24705 () | 40434..41138 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUV22_RS24710 () | 41204..41488 | + | 285 | Protein_45 | IS6 family transposase IS26 | Transposase |
| HUV22_RS24715 () | 41542..41760 | + | 219 | Protein_46 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUV22_RS24720 () | 41803..42737 | - | 935 | Protein_47 | IS3 family transposase ISEc36 | Transposase |
| HUV22_RS24725 () | 42808..43512 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUV22_RS24730 () | 43566..43784 | + | 219 | Protein_49 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUV22_RS24735 () | 43827..44761 | - | 935 | Protein_50 | IS3 family transposase ISEc36 | Transposase |
| HUV22_RS24740 () | 44832..45536 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUV22_RS24745 () | 45602..46147 | + | 546 | Protein_52 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUV22_RS24750 () | 46183..46598 | - | 416 | Protein_53 | IS1 family transposase | - |
| HUV22_RS24755 () | 46847..47248 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HUV22_RS24760 () | 47181..47438 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HUV22_RS24765 () | 47531..48184 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HUV22_RS24770 () | 48282..48422 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| HUV22_RS24775 () | 49123..49980 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| HUV22_RS24780 () | 49973..50455 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| HUV22_RS24785 () | 50448..50522 | - | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| HUV22_RS24790 () | 50754..51011 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| HUV22_RS24795 () | 51295..51501 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 51488..51549 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 51488..51549 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 51488..51549 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 51488..51549 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| HUV22_RS24800 () | 51805..51879 | - | 75 | Protein_63 | endonuclease | - |
| HUV22_RS24805 () | 52125..52337 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| HUV22_RS24810 () | 52473..53033 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| HUV22_RS24815 () | 53136..53996 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| HUV22_RS24820 () | 54055..54801 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| HUV22_RS24825 () | 54821..60091 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| HUV22_RS24830 () | 60173..60400 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| HUV22_RS24835 () | 60400..60798 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| HUV22_RS24840 () | 60807..62960 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| HUV22_RS24845 () | 63213..63944 | - | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| HUV22_RS24850 () | 63976..64473 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| HUV22_RS24855 () | 64489..67311 | - | 2823 | WP_174402699.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HUV22_RS24860 () | 67308..68681 | - | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| HUV22_RS24865 () | 68681..69094 | - | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| HUV22_RS24870 () | 69048..69389 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| HUV22_RS24875 () | 69319..69864 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HUV22_RS24880 () | 69851..70135 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HUV22_RS24885 () | 70216..70530 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| HUV22_RS24890 () | 70532..70879 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| HUV22_RS24895 () | 70895..71638 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HUV22_RS24900 () | 71631..71888 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| HUV22_RS24905 () | 71915..73723 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HUV22_RS24910 () | 73720..74358 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HUV22_RS24915 () | 74367..75359 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| HUV22_RS24920 () | 75356..75988 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| HUV22_RS24925 () | 75985..76371 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| HUV22_RS24930 () | 76368..78995 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| HUV22_RS24935 () | 79155..79376 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| HUV22_RS24940 () | 79511..80026 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HUV22_RS24945 () | 80023..80274 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| HUV22_RS24950 () | 80286..80516 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| HUV22_RS24955 () | 80470..81060 | - | 591 | WP_001376242.1 | conjugal transfer protein TraP | - |
| HUV22_RS24960 () | 81050..82477 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| HUV22_RS24965 () | 82477..83181 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| HUV22_RS24970 () | 83192..83758 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| HUV22_RS24975 () | 83780..84091 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HUV22_RS24980 () | 84106..84471 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| HUV22_RS24985 () | 84504..84899 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| HUV22_RS24990 () | 84998..85687 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| HUV22_RS24995 () | 85874..86257 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| HUV22_RS25000 () | 86578..87180 | + | 603 | WP_174402700.1 | hypothetical protein | VF |
| HUV22_RS25005 () | 87477..88298 | - | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| HUV22_RS25010 () | 88416..88703 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HUV22_RS25020 () | 89624..89782 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 89826..90050 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 89826..90050 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 89826..90050 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 89826..90050 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| HUV22_RS25025 () | 89862..90050 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| HUV22_RS25030 () | 90062..90781 | - | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| HUV22_RS25035 () | 90778..91212 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| HUV22_RS25040 () | 91267..91464 | - | 198 | Protein_110 | hypothetical protein | - |
| HUV22_RS25045 () | 91492..91725 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| HUV22_RS25050 () | 91793..92332 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| HUV22_RS25055 () | 92358..92564 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| HUV22_RS25065 () | 93660..94631 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HUV22_RS25070 () | 94631..95797 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| HUV22_RS25075 () | 96097..96794 | - | 698 | Protein_116 | IS1 family transposase IS1S | Transposase |
| HUV22_RS25080 () | 97279..99480 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| HUV22_RS25085 () | 99562..100839 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| HUV22_RS25090 () | 100836..102578 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| HUV22_RS25095 () | 102578..103526 | - | 949 | Protein_120 | N(6)-hydroxylysine O-acetyltransferase | VF |
| HUV22_RS25100 () | 103527..105251 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| HUV22_RS25105 () | 105387..106580 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| HUV22_RS25110 () | 106960..107340 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| HUV22_RS25115 () | 107681..108094 | - | 414 | Protein_124 | phosphopyruvate hydratase | - |
| HUV22_RS25120 () | 108092..108349 | + | 258 | Protein_125 | Tn3 family transposase | - |
| HUV22_RS25125 () | 108583..109440 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| HUV22_RS25130 () | 109437..110294 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| HUV22_RS25135 () | 110291..111118 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| HUV22_RS25140 () | 111118..112032 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| HUV22_RS25145 () | 112388..113085 | + | 698 | Protein_130 | IS1 family transposase IS1S | Transposase |
| HUV22_RS25150 () | 113265..113778 | - | 514 | Protein_131 | DUF4113 domain-containing protein | - |
| HUV22_RS25155 () | 113839..113943 | - | 105 | Protein_132 | AAA family ATPase | - |
| HUV22_RS25160 () | 113945..114268 | - | 324 | Protein_133 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|